Developmental trajectories of anxiety
The goal of our research group is to better understand the developmental trajectories of anxiety and anxiety disorders on different levels with the long-term goal to enhance therapeutic responses and to create preventive strategies.
SFB TRR 58
Within the SFB TRR 58/subproject Z02 the to date biggest sample of nearly 500 children and adolescents between 8 and 12 years underwent a fear conditioning and generalization paradigm and were characterized for psychological, environmental and genetic aspects. Most of these children were investigated again within a follow-up design to test which pathogenic parameters causes an anxiety disorder. Additionally, we investigate some further groups of participants – e.g. patients with anxiety disorders – with the same methods to compare the groups even with regard to prediction markers of anxiety and anxiety disorders.
For more information on the SFB TRR 58
PROTECT AD
Furthermore, within a multicenterBMBF study (PROTECT-AD „Differential Impact of Parental Participation on Intensified Exposure-Based Psychological Interventions in Anxiety Disorders in Children (PEACH)“) the differential impact of parental participation on intensified exposure-based psychological interventions in anxiety disorders in children aged 8 to 14 years with separation anxiety, specific phobia or social anxiety were investigated within a randomized investigation design. The therapeutic response will be measured after treatment and six month after treatment.
Research methods
Our research methods range from questionnaires, behavioral experiments (discriminative conditioning, generalization) to physiological and neural measures. Moreover, genetic and epigenetic markers of children and adolescents are of interest.
Research Team
Leader:
Prof. Dr. med. Marcel Romanos
Team:
Dr. rer. nat. Julia Reinhard, Post-Doktorandin
Anna Slyschak M.Sc., psychologische Doktorandin
Leonie Schneider B.Sc., Hilfswissenschaftlerin
Tania Mousikou, Hilfswissenschaftlerin
Anna Mittermeier, medizinische Doktorandin
Lillien Frey, medizinische Doktorandin
Jonas Daub, medizinischer Doktorand
Lisa Brandstetter, medizinische Doktorandin
Kimberly Mowat, medizinische Doktorandin
Julia Kühl, medizinische Doktorandin
Selected Publications
Schiele MA, Reinhard J, Reif A, Domschke K, Romanos M, Deckert J, Pauli P 2016
Developmental aspects of fear: Comparing the acquisition and generalization of conditioned fear in children and adults.
Developmental Psychobiology 58(4):471-481.
Go to publication
Reinhard J, Drepper C, Weber H, Schiele MA, Kneer K, Mittermeier A et al 2019
Anxiety risk SNPs on chromosome 2 modulate arousal in children in a fear generalization paradigm.
European Child & Adolescent Psychiatry 1-10
Go to publication
Contact
Telefon
Klinik und Poliklinik für KJPPP
Poliklinik und Privatambulanz
+49 931 201-78600
Zentrale Dienstnummer & Dienstarzt
+49 931 201-78888
Pforte Zentrum für Psychische Gesundheit
+49 931 201-76050
Sekretariat Tagesklinik
+49 931 250-8040
Direktion
Prof. Dr. Marcel Romanos
+49 931 201-78000
Stellvertretende Direktion
PD Dr. Regina Taurines
+49 931 201-78010
Anschrift
Klinik und Poliklinik für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie des Universitätsklinikums | Margarete-Höppel-Platz 1 | 97080 Würzburg | Deutschland