Hier finden Sie ausgewählte Publikationen zu Themenbereichen aus der Chirurgie I:

Flemming S, Burkard N, Renschler M, Vielmuth F, Meir M, Schick MA, Wunder C, Germer CT, Spindler V, Waschke J, Schlegel N. (2015) Soluble VEcadherin is involved in endothelial barrier breakdown in systemic inflammation and sepsis. Cardiovasc Res 107:32-44.

Jurowich CF, Otto C, Rikkala PR, Wagner N, Vrhovac I, Sabolic´ I, Germer CT, Koepsell H. (2015) Ileal Interposition in Rats with Experimental Type 2 Like Diabetes Improves Glycemic Control Independently of Glucose Absorption. J Diabetes Res 2015:490365.

Lutz M, Worschech A, Alb M, Gahn S, Bernhard L, Schwab M, Obermeir S, Einsele H, Kämmerer U, Heuschmann P, Klinker E, Otto C, Mielke S. (2015) Gender and pregnancy affect T cell response against tumor-associated antigens in healthy individuals: Results from a prospective study and implications for immunotherapy. Blood 125:261-272.

Seyfried F, Miras AD, Rotzinger L, Nordbeck A, Corteville C, Li JV, Schlegel N, Hankir M, Fenske W, Otto C, Jurowich C. (2015) Gastric bypass related effects on glucose control, β-cell function and morphometry in the obese Zucker rat. Obes Surg [Epub ahead of print].

Wiegering A, Uthe FW, Jamieson T, Ruoss Y, Hüttenrauch M, Küspert M, Pfann C, Nixon C, Herold S, Walz S, Taranets L, Germer CT, Rosenwald A, Sansom OJ, Eilers M. (2015) Targeting Translation Initiation Bypasses Signaling Crosstalk Mechanisms That Maintain High MYC Levels in Colorectal Cancer. Cancer Discov 5:768-781.

Publikationen 2014 und älter

Marshall A, Santollo J, Corteville C, Lutz TA, Daniels D. (2014) Roux-en-Y gastric bypass does not affect daily water intake or the drinking response to dipsogenic stimuli in rats. Am J Physiol Regul Integr Comp Physiol 307;2:R114-20.

López CL, Meyer T, Heuer S, Kranke P, Debus F, Wurmb T, Kühne CA. (2014) [In-hospital trauma management - beyond routine in trauma resuscitation]. Anasthesiol Intensivmed Notfallmed Schmerzther 49;9:544-53;quiz 554.

Folprecht G, Gruenberger T, Bechstein W, Raab HR, Weitz J, Lordick F, Hartmann JT, Stoehlmacher-Williams J, Lang H, Trarbach T, Liersch T, Ockert D, Jaeger D, Steger U, Suedhoff T, Rentsch A, Köhne CH. (2014) Survival of patients with initially unresectable colorectal liver metastases treated with FOLFOX/cetuximab or FOLFIRI/cetuximab in a multidisciplinary concept (CELIM study). Ann Oncol 25;5:1018-25.

Brinkhaus G, Lock JF, Malinowski M, Denecke T, Neuhaus P, Hamm B, Gebauer B, Stockmann M. (2014) CT-guided high-dose-rate brachytherapy of liver tumours does not impair hepatic function and shows high overall safety and favourable survival rates. Ann Surg Oncol 21;13:4284-92.

Esquivel J, Lowy AM, Markman M, Chua T, Pelz J, Baratti D, Baumgartner JM, Berri R, Bretcha-Boix P, Deraco M, Flores-Ayala G, Glehen O, Gomez-Portilla A, González-Moreno S, Goodman M, Halkia E, Kusamura S, Moller M, Passot G, Pocard M, Salti G, Sardi A, Senthil M, Spilioitis J, Torres-Melero J, Turaga K, Trout R. (2014) The American Society of Peritoneal Surface Malignancies (ASPSM) Multiinstitution Evaluation of the Peritoneal Surface Disease Severity Score (PSDSS) in 1,013 Patients with Colorectal Cancer with Peritoneal Carcinomatosis. Ann Surg Oncol 21;13:4195-201.

Hertlein T, Sturm V, Lorenz U, Sumathy K, Jakob P, Ohlsen K. (2014) Bioluminescence and 19F magnetic resonance imaging visualize the efficacy of lysostaphin alone and in combination with oxacillin against Staphylococcus aureus in murine thigh and catheter-associated infection models. Antimicrob Agents Chemother 58;3:1630-8.

Wiegering A, Isbert C, Dietz UA, Kunzmann V, Ackermann S, Kerscher A, Maeder U, Flentje M, Schlegel N, Reibetanz J, Germer CT, Klein I. (2014) Multimodal therapy in treatment of rectal cancer is associated with improved survival and reduced local recurrence - a retrospective analysis over two decades. BMC Cancer 14:816.

Zeidler C, Woelfle J, Draaken M, Mughal SS, Große G, Hilger AC, Dworschak GC, Boemers TM, Jenetzky E, Zwink N, Lacher M, Schmidt D, Schmiedeke E, Grasshoff-Derr S, Märzheuser S, Holland-Cunz S, Schäfer M, Bartels E, Keppler K, Palta M, Leonhardt J, Kujath C, Rißmann A, Nöthen MM, Reutter H, Ludwig M. (2014) Heterozygous FGF8 mutations in patients presenting cryptorchidism and multiple VATER/VACTERL features without limb anomalies. Birth Defects Res A Clin Mol Teratol 100;10:750-9.

Wilson BJ, Saab KR, Ma J, Schatton T, Pütz P, Zhan Q, Murphy GF, Gasser M, Waaga-Gasser AM, Frank NY, Frank MH. (2014) ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit. Cancer Res 74;15:4196-207.

Schlegel N, Waschke J. (2014) cAMP with other signaling cues converges on Rac1 to stabilize the endothelial barrier- a signaling pathway compromised in inflammation. Cell Tissue Res 355;3:587-96.

Dietz UA, Germer CT. (2014) [Complications of hernia surgery]. Chirurg 85;2:96.

von Rahden BH, Filser J, Seyfried F, Veldhoen S, Reimer S, Germer CT. (2014) [Diagnostics and therapy of achalasia]. Chirurg 85;12:1055-63.

Germer CT. (2014) [Diverticular disease of the colon]. Chirurg 85;4:280.

Wiegering A, Herrmann K, Bluemel C, Buck AK, Germer CT. (2014) [Importance of FDG-PET/CT for surgery of rectal cancer]. Chirurg 85;6:487-92.

Reibetanz J, Germer CT. (2014) [Influence of structured CEA determination and CT-scan to detect recurrence of colorectal cancer: results of the randomized clinical FACS study]. Chirurg 85;7:642.

Dietz UA, Wiegering A, Germer CT. (2014) [Intervention-specific complications of hernia surgery]. Chirurg 85;2:97-104.

Schlegel N, Flemming S, Meir M, Germer CT. (2014) [Is a different view on the pathophysiology of sepsis the key for novel therapeutic options?]. Chirurg 85;8:714-9.

Germer CT. (2014) [Laparoscopic oncological surgery of the lower gastrointestinal tract: state of evidence]. Chirurg 85;7:568-9.

Isbert C, Germer CT. (2014) [Open coloproctectomy with ileoanal J-pouch reconstruction].Chirurg 85;3:231-5.

von Rahden BH, Filser J, Reimer S, Inoue H, Germer CT. (2014) [Peroral endoscopic myotomy for treatment of achalasia. Literature review and own initial experience]. Chirurg 85;5:420-32.

Reibetanz J, Germer CT. (2014) [Sexual function disorders and micturition problems after laparoscopic and open rectal cancer surgery]. Chirurg 85;11:1015.

Jurowich C, Seyfried F, Germer CT. (2014) [Sigmoid diverticulitis: indications and timing of surgery]. Chirurg 85;4:304-7.

Corteville C, Fassnacht M, Bueter M. (2014) [Surgery as pluripotent instrument for metabolic disease. What are the mechanisms?]. Chirurg 85;11:963-8.

Kim M, Reibetanz J, Schlegel N, Krajinovic K, Köstler H, Germer CT, Isbert C. (2014) Recurrence after perineal rectosigmoidectomy: when and why? Colorectal Dis 16;11:920-4.

Malinowski M, Jara M, Lüttgert K, Orr J, Lock JF, Schott E, Stockmann M. (2014) Enzymatic liver function capacity correlates with disease severity of patients with liver cirrhosis: a study with the LiMAx test. Dig Dis Sci 59;12:2983-91.

Kruis W, Germer CT, Leifeld L, German Society for Gastroenterology, Digestive and Metabolic Diseases and The German Society for General and Visceral Surgery. (2014) Diverticular disease: guidelines of the german society for gastroenterology, digestive and metabolic diseases and the german society for general and visceral surgery. Digestion 90;3:190-207.

Peter S, Bultinck J, Myant K, Jaenicke LA, Walz S, Müller J, Gmachl M, Treu M, Boehmelt G, Ade CP, Schmitz W, Wiegering A, Otto C, Popov N, Sansom O, Kraut N, Eilers M. (2014) Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase. EMBO Mol Med 6;12:1525-41.

Klinge U, Dietz U, Fet N, Klosterhalfen B. (2014) Characterisation of the cellular infiltrate in the foreign body granuloma of textile meshes with its impact on collagen deposition. Hernia18;4:571-8.

Wiegering A, Sinha B, Spor L, Klinge U, Steger U, Germer CT, Dietz UA. (2014) Gentamicin for prevention of intraoperative mesh contamination: demonstration of high bactericide effect (in vitro) and low systemic bioavailability (in vivo). Hernia 18;5:691-700.

Dietz UA, Winkler MS, Härtel RW, Fleischhacker A, Wiegering A, Isbert C, Jurowich C, Heuschmann P, Germer CT. (2014) Importance of recurrence rating, morphology, hernial gap size, and risk factors in ventral and incisional hernia classification. Hernia 18;1:19-30.

Oesterreich B, Lorenz B, Schmitter T, Kontermann R, Zenn M, Zimmermann B, Haake M, Lorenz U, Ohlsen K. (2014) Characterization of the biological anti-staphylococcal functionality of hUK-66 IgG1, a humanized monoclonal antibody as substantial component for an immunotherapeutic approach. Hum Vaccin Immunother 10;4:926-37.

Jurowich CF, Seyfried F, Miras AD, Bueter M, Deckelmann J, Fassnacht M, Germer CT, Thalheimer A.(2014) Does bariatric surgery change olfactory perception? Results of the early postoperative course. Int J Colorectal Dis 29;2:253-60.

Wiegering A, Uthe FW, Hüttenrauch M, Mühling B, Linnebacher M, Krummenast F, Germer CT, Thalheimer A, Otto C. (2014) The impact of pyrvinium pamoate on colon cancer cell viability. Int J Colorectal Dis 29;10:1189-98.

Germer CT, Isbert C. (2014) [Operative therapy of chronic inflammatory bowel diseases. Indications and importance]. Internist (Berl) 55;8:918-24.

Esquivel J, Piso P, Verwaal V, Bachleitner-Hofmann T, Glehen O, González-Moreno S, Deraco M, Pelz J, Alexander R, Glockzin G. (2014) American Society of Peritoneal Surface Malignancies opinion statement on defining expectations from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with colorectal cancer. J Surg Oncol 110;7:777-8.

Prada-Villaverde A, Esquivel J, Lowy AM, Markman M, Chua T, Pelz J, Baratti D, Baumgartner JM, Berri R, Bretcha-Boix P, Deraco M, Flores-Ayala G, Glehen O, Gomez-Portilla A, González-Moreno S, Goodman M, Halkia E, Kusamura S, Moller M, Passot G, Pocard M, Salti G, Sardi A, Senthil M, Spiliotis J, Torres-Melero J, Turaga K, Trout R. (2014) The American Society of Peritoneal Surface Malignancies evaluation of HIPEC with Mitomycin C versus Oxaliplatin in 539 patients with colon cancer undergoing a complete cytoreductive surgery. J Surg Oncol 110;7:779-85.

Busch A, Reibetanz J, Flemming S, Steger U, Kellersmann R. (2014) Celiacobihepatic venous bypass for liver revascularization in a patient with intrahepatic contained rupture of a common hepatic artery aneurysm. J Vasc Surg 60;1:230-2.

Saisawat P, Kohl S, Hilger AC, Hwang DY, Yung Gee H, Dworschak GC, Tasic V, Pennimpede T, Natarajan S, Sperry E, Matassa DS, Staji? N, Bogdanovic R, de Blaauw I, Marcelis CL, Wijers CH, Bartels E, Schmiedeke E, Schmidt D, Märzheuser S, Grasshoff-Derr S, Holland-Cunz S, Ludwig M, Nöthen MM, Draaken M, Brosens E, Heij H, Tibboel D, Herrmann BG, Solomon BD, de Klein A, van Rooij IA, Esposito F, Reutter HM, Hildebrandt F. (2014) Whole-exome resequencing reveals recessive mutations in TRAP1 in individuals with CAKUT and VACTERL association. Kidney Int 85;6:1310-7.

Wiegering A, Endter F, Wiegering VA, Germer CT, Maroske J. (2014) Bowl obstruction due to an incomplete obliterated omphalomesenteric duct. Klein Padiatr 226;2:80-1.

Trebing J, Lang I, Chopra M, Salzmann S, Moshir M, Silence K, Riedel SS, Siegmund D, Beilhack A, Otto C, Wajant H. (2014) A novel llama antibody targeting Fn14 exhibits anti-metastatic activity in vivo. MAbs 6;1:297-308.

Semmlinger A, Fliesser M, Waaga-Gasser AM, Dragan M, Morton CO, Einsele H, Loeffler J. (2014) Fever-range temperature modulates activation and function of human dendritic cells stimulated with the pathogenic mould Aspergillus fumigatus. Med Mycol 52;4:438-44.

Johannes A, Kredel M, Zollhoefer B, Schlegel N, von Kirschbaum C, Brederlau J, Kranke P, Roewer N, Muellenbach R. (2014) Influence of apneic oxygenation and minimal tidal volumes on ventilator-associated lung injury. Minerva Anestesiol 80;5:526-36.

Gockel I, Becker J, Wouters MM, Niebisch S, Gockel HR, Hess T, Ramonet D, Zimmermann J, Vigo AG, Trynka G, de León AR, de la Serna JP, Urcelay E, Kumar V, Franke L, Westra HJ, Drescher D, Kneist W, Marquardt JU, Galle PR, Mattheisen M, Annese V, Latiano A, Fumagalli U, Laghi L, Cuomo R, Sarnelli G, Müller M, Eckardt AJ, Tack J, Hoffmann P, Herms S, Mangold E, Heilmann S, Kiesslich R, von Rahden BH, Allescher HD, Schulz HG, Wijmenga C, Heneka MT, Lang H, Hopfner KP, Nöthen MM, Boeckxstaens GE, de Bakker PI, Knapp M, Schumacher J. (2014) Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. Nat Genet 46;8:901-4.

Wiegering A, Korb D, Thalheimer A, Kämmerer U, Allmanritter J, Matthes N, Linnebacher M, Schlegel N, Klein I, Ergün S, Germer CT, Otto C. (2014) E7080 (lenvatinib), a multi-targeted tyrosine kinase inhibitor, demonstrates antitumor activities against colorectal cancer xenografts. Neoplasia 16;11:972-81.

Miras AD, Seyfried F, Phinikaridou A, Andia ME, Christakis I, Spector AC, Botnar RM, le Roux CW. (2014) Rats fed diets with different energy contribution from fat do not differ in adiposity. Obes Facts 7;5:302-10.

Seyfried F, Bueter M, Spliethoff K, Miras AD, Abegg K, Lutz TA, le Roux CW. (2014) Roux-en Y gastric bypass is superior to duodeno-jejunal bypass in improving glycaemic control in Zucker diabetic fatty rats. Obes Surg 24;11:1888-95.

Hensel F, Timmermann W, von Rahden BH, Rosenwald A, Brändlein S, Illert B. (2014) Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1. Oncol Rep 31;3:1059-66.

Flemming S, Schlegel N, Wunder C, Meir M, Baar W, Wollborn J, Roewer N, Germer CT, Schick MA. (2014) Phosphodiesterase 4 inhibition dose dependently stabilizes microvascular barrier functions and microcirculation in a rodent model of polymicrobial sepsis. Shock 41;6:537-45.

Bittner R, Bingener-Casey J, Dietz U, Fabian M, Ferzli GS, Fortelny RH, Köckerling F, Kukleta J, Leblanc K, Lomanto D, Misra MC, Bansal VK, Morales-Conde S, Ramshaw B, Reinpold W, Rim S, Rohr M, Schrittwieser R, Simon T, Smietanski M, Stechemesser B, Timoney M, Chowbey P, International Endohernia Society (IEHS). (2014) Guidelines for laparoscopic treatment of ventral and incisional abdominal wall hernias (International Endohernia Society (IEHS)-part 1. Surg Endosc 28;1:2-29.

Bittner R, Bingener-Casey J, Dietz U, Fabian M, Ferzli G, Fortelny R, Köckerling F, Kukleta J, LeBlanc K, Lomanto D, Misra M, Morales-Conde S, Ramshaw B, Reinpold W, Rim S, Rohr M, Schrittwieser R, Simon T, Smietanski M, Stechemesser B, Timoney M, Chowbey P. (2014) Guidelines for laparoscopic treatment of ventral and incisional abdominal wall hernias (International Endohernia Society [IEHS])-Part III. Surg Endosc 28;2:380-404.

Kannen V, Moreira MC, Waaga-Gasser AM, Modiano P, Elias Junior J, Fernandes CR, Garcia SB. (2014) Partial lipectomy reduces dimethylhydrazine-induced carcinogenic initiation in the colon of rats. Toxicology 316:9-13.

Busch A, Suellner J, Anger F, Meir M, Kickuth R, Lorenz U, Wildenauer R. (2014) Critical care of kyphoscoliotic type Ehlers-Danlos syndrome with recurrent vascular emergencies. Vasa 43;3:316-21.

Engelhardt M, Spech E, Diener H, Faller H, Augustin M, Debus ES. (2014) Validation of the disease-specific quality of life Wuerzburg Wound Score in patients with chronic leg ulcer. Vasa 43;5:372-9.

Steinbach C, Stockmann M, Jara M, Bednarsch J, Lock JF. (2014) Accidentally ingested toothpicks causing severe gastrointestinal injury: a practical guideline for diagnosis and therapy based on 136 case reports. World J Surg 38;2:371-7.

Leifeld L, Germer CT, Böhm S, Dumoulin FL, Häuser W, Kreis M, Labenz J, Lembcke B, Post S, Reinshagen M, Ritz JP, Sauerbruch T, Wedel T, von Rahden B, Kruis W. (2014) [S2k guidelines diverticular disease/diverticulitis]. Z Gastroenterol 52;7:663-710.

Keller K, Krenzer-Scheidemantel G, Meyer T. (2014) [A systematic analysis of the compression pressure in the compression therapy for scars in childhood with the help of the Kikuhime® pressure device]. Zentralbl Chir 139;6:638-42.

Thiede A, Zimmermann HJ. (2014) [Complications after secondary large intestine perforation: expert testimony and court decision]. Zentralbl Chir 139;4:374-8.

Thiede A, Zimmermann HJ. (2014) [Delayed listing as malpractice?]. Zentralbl Chir 139;2:146-50.

Hoefling K, Sperling P, Meyer T. (2014) [Time of operative treatment of maldescensus testis in childhood - wishes and reality]. Zentralbl Chir 139;6:627-31.

Thiede A, Zimmermann HJ. (2014) [Wound healing problems after iliac crest operation: appellate decision]. Zentralbl Chir 139;1:12-5.


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