The aim of this program is to provide practical experience in a wide range of scientific techniques related to pain research.

The three-hour program – 1 p.m. to 4 p.m. – includes the following offers on Friday, April 26th, 2024:

• Molecular players in pain resolution – behavioural and morphological analyses
• 3D Cell Culture
• RNA Sequencing Analysis and Single Cell
• Immunolabeling and imaging of skin biopsies

Courses are conceived and delivered by the principal investigators and/or scientific experts from their respective working groups.

For detailed information and event location, please refer to the Hands-on Classes program.

All sessions will be face-to-face and held in English (unless explicitly stated otherwise) promoting an interactive and immersive learning environment for all participants.

The two project leaders Univ.-Prof. Mirko Pham, MD, Clinic Director of Neuroradiology and Univ.-Prof. Cordula Matthies, MD, Deputy Clinic Director of Neurosurgery at the University Hospital Würzburg, will speak on the topic of "Gene-based neuropathies". The Clinician Scientists Eva Rampeltshammer, MD, and Simon Weiner, MD, as well as the doctoral student Annsophie Amann will also present their results on this topic.

Further information on project 2

Prof. Claudia Sommer, MD, Speaker of the CRU 5001 and Senior Consultant at the Department of Neurology of the University Hospital of Würzburg, together with Dr. Aikaterini Papagianni, MD, and the doctoral student Yuying Jin will give an update on the topic “Skin Platform” of the Service Project “Biosample-Analysis and Biosamples”.

Further information on Service Project “Biosample-Analysis and Biosamples”

Changes to ion channels due to genetic or acquired mutations in specific proteins can lead to a lowering of the excitation threshold of neurons. This promotes the transmission of pain impulses and thus the development of chronic pain. In his lecture "Building excitable membranes in sensory neurons," Prof. Dib-Hajj will report on his research expertise, focusing on molecular changes, particularly those observed in sodium ion channels.

Further details about Prof. Dr. Dib Hajj´s lecture in the flyer.

Prof. Dr. Sulayman Dib-Hajj is a neurologist and pain researcher at the Yale School of Medicine in Connecticut, USA. Through several publications on the topic of ion channels and their role in the development of chronic pain, he has earned worldwide recognition in the field. He will meet with members of CRU 5001 in May for personal knowledge and information exchange.

Further details about Prof. Dr. Dib-Hajj's visit.

Project leaders Univ.-Prof. Dr. Robert Kittel, Institute of Biology at the University of Leipzig, and Univ.-Prof. Heike Rittner, MD, Head of the Pain Centre at the University Hospital of Würzburg, will speak on the topic "Function of the adhesion GPCR CIRL in pain perception and pain relief" from Project 6 of the Clinical Research Unit 5001. The postdoc Dr. Mareike Selcho, and the doctoral students Mariam Atalla and Aishwarya Aravamudhan will also present their results on the same topic.

Further information on project 6

Speakers on the topic of "Bortezomib-induced polyneuropathy" are the project leaders Univ.-Prof. Martin Kortüm, holder of the Chair for Translational Myeloma Research, and Univ.-Prof. Claudia Sommer, Senior Consultant at the Department of Neurology of the University Hospital of Würzburg. The doctoral student Nadine Cebulla will present her results on the same topic.

Further information on project 1

The aim of this program is to provide practical experience in a wide range of scientific techniques related to pain research.

The three-hour program – 1 p.m. to 4 p.m. – includes the following offers on Friday, October 11th, 2024:

• Immunolabeling and imaging of skin biopsies
• Pharmacotherapy: compliance and drug safety in pain treatment
• Pain behavioural tests: troubleshooting

Courses are conceived and delivered by the principal investigators and/or scientific experts from their respective working groups.

For detailed information and event location, please refer to the Hands-on Classes program.

All sessions will be face-to-face and held in English (unless explicitly stated otherwise) promoting an interactive and immersive learning environment for all participants.

Project leader, Univ.-Prof. Claudia, Sommer, Senior Consultant at the Department of Neurology of the University Hospital of Würzburg, will speak on the topic "Influence of the social environment on pain perception”. The doctoral student Mona Hashemianahmadi will present her results on the same topic.

Further information on project 5

Project leaders Dr. Susanne Krug from the Charité - Universitätsmedizin Berlin and Univ.-Prof. Heike Rittner, MD, Head of the Pain Center at the University Hospital of Würzburg, will speak on the topic "Influence of netrin on the blood-nerve barrier". Postdoc Dr. Jeremy Chen and the doctoral student Lukas Knobe will also present their latest results.

Further information on Project 7