AI for detecting polyps in real-life conditions

Colorectal cancer is one of the most common types of cancer in both men and women. Colonoscopy can detect precursor lesions for cancer, and the risk of disease can be minimized by removing these lesions during the procedure. Various factors affect the quality of colonoscopy examinations. In addition to good bowel preparation, the examiner’s adenoma detection rate is crucial.

Although artificial intelligence (AI) can provide remarkably good results for detecting polyps during colonoscopy (with computer-aided detection, CADe), many AI systems are trained using good-quality still images, which do not reflect conditions in real clinical scenarios. In this project, we developed an AI system for polyp detection, called ENDOMIND. This AI system uses deep learning to identify polyps during colonoscopy. To develop the system, we combined training material from six different centers, involving three different endoscope manufacturers. A team of advanced gastroenterologists and medical assistants was assembled in order to manually annotate more than 300,000 images, which were used to train the AI system. The dataset compiled consists of sequences of polyp images. It is of high quality, since the focus was on the polyp sequence during the first 1–3 seconds, which is decisive for detecting polyps in a real clinical scenario.

In addition, we built a software backbone that is able to apply the polyp detection system in real time during routine colonoscopies. We have demonstrated that the AI system developed in this way has state-of-the-art capabilities, as it was validated using an open-source benchmarking dataset and obtained the highest score in October 2021.

The research for this project is part of the “Baden-Württemberg Health-Care Location Forum” (Forum Gesundheitsstandort Baden-Württemberg), sponsored by the Ministry of Science, Research and Art of the state of Baden-Württemberg.

The project has been developed in collaboration with Prof. Dr. Frank Puppe, Head of the Chair for Artificial Intelligence and Knowledge Systems, Julius Maximilians University of Würzburg. Other participants include Prof. Dr. Dr. W.G. Zoller, Katharinenhospital Stuttgart, and Prof. Dr. J.F. Riemann, Stiftung LebensBlicke.

The CADe system (ENDOMIND) is freely available for research purposes.

Publication:
Fitting D. et al. (2022)
A video based benchmark data set (ENDOTEST) to evaluate computer-aided polyp detection systems.
Scandinavian Journal of Gastroenterology 2022
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Software download link

For any questions and additional explanations please feel free to contact the author Alexander Hann.
E-mail: hann_a@ ukw.de 


Funding

Logo Forum Gesundheitsstandort Baden-Württemberg
Logo Eva Mayr-Stihl Stiftung

Contact

Portraitfoto von PD Dr. med. Alexander Hann

PD Dr. med.
Alexander Hann

Head of the working group

+49 931 201-45918

Portraitfoto von Joel Troya


Joel Troya

Member of the working group

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Adrian Krenzer

Team InExEn

Portraitfoto von Michael Banck


Michael Banck

Member of the working group


Zita Saßmannshausen

Member of the working group

Portraitfoto von Boban Sudarevic


Boban Sudarevic

Member of the working group

Address

Medizinische Klinik und Poliklinik II | Gastroenterologie | Oberdürrbacher Straße 6 | Haus A4 | 97080 Würzburg | Deutschland

Auvera Haus | Grombühlstraße 12 | 97080 Würzburg | Deutschland

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