Third-Party Funded Projects on Anxiety Disorders
BMBF-Network „Anxiety Disorders“ (Protect AD)
Local project leader P1 (adult RCT) and project leader P3 (virtual reality): Prof. Dr. Paul Pauli
Local project leader P2 (children's RCT): Prof. Dr. Marcel Romanos
Local project leader P4 (neuroimaging): Prof. Dr. Ulrike Lüken
Project leader P5 ((epi-)genetics): Prof. Dr. Jürgen Deckert, Prof. Dr. Dr. Katharina Domschke
Anxiety disorders represent the largest group of mental disorders and, if left untreated, can lead to chronification and other (mental) comorbidities. The further development and optimisation of psychotherapeutic treatment approaches is of great importance. The Federal Ministry of Education and Research (BMBF) is therefore promoting research into mental illnesses in a large-scale initiative. The research network "Anxiety Disorders" includes two large psychotherapy studies for children and adults with anxiety disorders. A total of seven centres participate in this study (Berlin, Bochum, Dresden, Greifswald, Marburg Münster, Würzburg).
According to new results of preclinical studies, extinction learning is the central mechanism of action of exposure-based cognitive behavioral therapies in anxiety disorders and also offers the possibility to increase the effectiveness of treatment through optimized extinction. Two multicenter clinical trials will investigate whether psychotherapy can be optimized by different elements. The clinical therapy study will be accompanied by several experimental add-on studies investigating underlying mechanisms, moderators and predictors of therapeutic success.
Further information can be found on the webseite of the research network.