Third-Party Funded Projects on Anxiety Disorders

The Collaborative Research Centre Transregio 58 (SFB TRR 58) "Fear, Anxiety, Anxiety Disorders"

Speaker: Hans-Christian Pape (Physiology, Münster)
Local speaker: Paul Pauli (Institute of Psychology)
3. funding period 2016-2020

Further information on the SFB TRR 58 including a description of all subprojects can be found here.

At our hospital, we are working on the following subprojects:


The influence of early life stress on anxiety-like behavior: the significance of the pre- and postnatal phase for gene x environment interactions and the modifiability of its outcome later in life

Project leader: Norbert Sachser, Klaus-Peter Lesch und Thomas Seidenbecher


Stress-induced programming in serotonin (5-HT) system-modified mice: epigenetic editing as a strategy to cope with anxiety

Project leader: Daniel van den Hove, Klaus-Peter Lesch und Angelika Schmitt


Targetable (Epi)Genetic, Physiological and Neuroimaging Risk Markers of Anxiety Sensitivity: A Developmental, Cross-Disorder Prevention Study of Separation Anxiety and Panic Disorder

Project leader: Katharina Domschke, Susanne Neufang


Phasic and sustained fear in humans: neural basis and implication for anxiety disorders

Project leader: Martin Herrmann, Thomas Straube


Exposure treatment in anxiety disorders: proof of principle of an a priori response prediction approach

Project leader: Ulrike Lüken, Udo Dannlowksi


Gene-environment interactions, generalization and neural circuits in dimensional endophenotypes of fear and anxiety in adults and children: development and reversibility

Project leader: Katharina Domschke, Ulrike Lüken, Udo Dannlowski, Tina B. Lonsdorf, Marcel Romanos, Paul Pauli and Jürgen Deckert

Z02-Follow up after 4 resp. 8 years

Project duration: 2022-2025

Project leader: Julia Reinhardt, Andre Pittig and Angelika Erhardt-Lehmann

Working group members: Marcel Romanos, Jürgen Deckert and Theresa Troll

Head of Hospital

Portraitfoto von Prof. Dr. med. Jürgen Deckert

Prof. Dr. med.
Jürgen Deckert

Head of the Department of Psychiatry, Psychosomatics and Psychotherapy

+49 931 201-77000