Our main focus is on:

  • Research on disease mechanisms for neuro­degenerative disorders, in particular motoneuron disorders.
  • Generation and analysis of cell culture and mouse ­models for motoneuron disease.
  • Development of therapeutic strategies for treatment of amyotrophic lateral sclerosis and spinal muscular ­atrophy.
  • Characterization and analysis of signalling p­athways for neuronal survival, differentiation, axon growth and neuronal cell death.
  • Genetic analysis of patients with motoneuron ­disease.
  • Participation in European (Euro-MOTOR) and
  • German Networks (MND-Disease Network, BMBF Dystonia Network, ForIPS) for Neuro­degenerative Disorders