Intervention and health services in ADHD

As part of the ESCAlife research network and the INTEGATE-ADHD study, the Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy (CAPPP) at Würzburg University Hospital is investigating the effectiveness of treatment, the quality of care, and the frequency of occurrence of ADHD in children and adolescents in Germany. This includes the search for biomarkers, for example to predict the course of the disease and to select individually tailored therapy options.


Our research network ESCAlife (Evidence-based Stepped Care of ADHD across the lifespan) includes four multi-center trials on psychotherapy of ADHD from kindergarten to adulthood (BMBF funding program “Research Network on Mental Diseases”). ESCAlife is managed by the Central Institute for Mental Health in Mannheim. The CAPPP Würzburg is the leading center of the controlled psychotherapy study for the treatment of ADHD in adolescents (ESCAadol) and is involved as a study center in trials on the treatment of ADHD in kindergarten and school age. Cross-sectional projects of ESCAlife serve to identify biomarkers that predict outcome. The ESCAlife research program will improve ADHD treatment algorithms through adaptive strategies that take into account age, gender, symptom severity, co-morbidity and treatment response. Our trials are carried out in routine outpatient clinical care in order to enable highly generalizable study results. These will be available from 2021.


In addition to evidence-based treatment strategies, improving the quality of care requires reliable knowledge of the prevalence of ADHD and the status of care in Germany. This is investigated by the CAPPP in cooperation with DAK-Gesundheit, the Robert Koch Institute, the University Medical Center Hamburg-Eppendorf, the Economic Research Institute WiFor and the Institute for Clinical Epidemiology and Biometry of the University of Würzburg in the network "ADHD in Germany - INTEGATE-ADHD" (funded by the innovation fund of the federal committee G-BA). The CAPPP is leading a project to compare the prevalence estimates of ADHD using registry entries, surveys and guideline-based clinical assessment. Other projects of INTEGRATE-ADHD are investigating the availability and use of care services for ADHD and health economics. INTEGRATE-ADHD will start in 2021.

KJPPP and ADHD research

With ESCAlife and INTEGRATE-ADHD, our research tradition on ADHD is continued, which includes the Clinical Research Group 125 from 2004 to 2009 (sponsored by the DFG) and the research network ADHDnet in the BMBF funding program "Research Networks on Psychotherapy" from 2006 to 2013.

Research Team

PD Dr. phil. Thomas Jans

Team ESCAlife-Coordination:
Prof. Dr. med. Marcel Romanos
Dr. rer. nat. Julia Geissler
Annette Nowak

Dr. rer. nat. Carsten Drepper
Zuzana Fouskova

Clinical stuff – psychotherapy:
Nadja Becker
Julia Gläser
Verena Hartlieb
Silke Hauck
Christin Heim
Kristin Möllers
Corinna Otte
Isabel Paul
Christin Scheiner

Clinical stuff – medical management:
Dr. med. Stefanie Fekete
Dr. med. Michaela Linke
Dr. med. Carolin Steinmetz

Clinical stuff – assessment:
Nadja Becker
Dr. med. Annalena Berner
Verena Hartlieb
Silke Hauck
Christin Heim
Corinna Otte
Isabel Paul

Auxiliary scientists:
Adrian Dernbach
Lea Zwilling
Lea Brosig

Prof. Dr. med. Marcel Romanos

Project management and assessments:
Dr. med. Annalena Berner
Dr. Vanessa Scholz
Leila Hetzke

Selected Publications

Geissler, J., Jans, T., Banaschewski, T., Becker, K., Renner, T., Brandeis, D., Döpfner, M., Dose, C., Hautmann, C., Holtmann, M., Jenkner, C., Millenet, S., Romanos, M. (2018)
Individualised short-term therapy for adolescents impaired by attention-deficit/hyperactivity disorder despite previous routine care treatment (ESCAadol) – Study protocol of a randomised controlled trial within the consortium ESCAlife
Trials 19(1), 254
Go to publication

Geissler JM, Vloet TD, Strom N, Jaite C, Graf E, Kappel V, Warnke A, Jacob C, Hennighausen K, Haack-Dees B, Schneider-Momm K, Matthies S, Rösler M, Retz W, Hänig S, Gontard A von, Sobanski E, Alm B, Hohmann S, Poustka L, Colla M, Gentschow L, Freitag CM, Häge A, Holtmann M, Becker K, Philipsen A, Jans T (2019)
Does helping mothers in multigenerational ADHD also help children in the long run? 2-year follow-up from baseline of the AIMAC randomized controlled multicentre trial
Eur Child Adolesc Psychiatry 64(2): 218
Go to publication

Häge, A., Alm, B., Banaschewski, T., Becker, K., Colla, M., Freitag, C., Geissler, J., von Gontard, A., Graf, E., Haack-Dees, B., Hänig, S., Hennighausen, K., Hohmann, S., Jacob, C., Jaite, C., Jennen-Steinmetz, C., Kappel, V., Matthies, S., Philipsen, A., Poustka, L., Retz, W., Rösler, M., Schneider-Momm, K., Sobanski, E., Vloet, T.D., Warnke, A., Jans, T. (2018)
Does the efficacy of parent-child training depend on maternal symptom improvement? Results from a randomized controlled trial on children and mothers both affected by attention-deficit/hyperactivity disorder (ADHD)
European Child & Adolescent Psychiatry 27(8), 1011–1021.
Go to publication

Jaite, C., van Noort, B.M., Vloet, T.D., Graf, E., Kappel, V., Geissler, J., Warnke, A., Jacob, C., Groß-Lesch, S., Hennighausen, K., Haack-Dees, B., Schneider-Momm, K., Philipsen, A., Matthies, S., Rösler, M., Retz, W., Hänig, S., von Gontard, A., Sobanski, E., Alm, B., Hohmann, S., Häge, A., Poustka, L., Colla, M., Gentschow, L., Freitag, C.M., Becker, K., Jans, T. (2019)
A multicentre randomized controlled trial on trans-generational attention deficit/hyperactivity disorder (ADHD) in mothers and children (AIMAC): an exploratory analysis of predictors and moderators of treatment outcome
Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie 47(1), 49–65.
Go to publication

Hautmann, C., Döpfner, M., Katzmann, J., Schürmann, S., Wolff Metternich-Kaizman, T., Jaite, C., Kappel, V., Geissler, J., Warnke, A., Jacob, C., Hennighausen, K., Haack-Dees, B., Schneider-Momm, K., Philipsen, A., Matthies, S., Rösler, M., Retz, W., von Gontard, A., Sobanski, E., Alm, B., Hohmann, S., Häge, A., Poustka, L., Colla, M., Gentschow, L., Freitag, C.M., Becker, K., Jans, T. (2018)
Sequential treatment of ADHD in mother and child (AIMAC study): importance of the treatment phases for intervention success in a randomized trial
BMC Psychiatry 18(1), 388
Go to publication


Portraitfoto von Dr. phil. Thomas Jans

Prof. Dr. phil.
Thomas Jans

Leitender Psychologe

+49 931 201-78010



Klinik und Poliklinik für KJPPP
Poliklinik und Privatambulanz
+49 931 201-78600

Zentrale Dienstnummer & Dienstarzt
+49 931 201-78888

Pforte Zentrum für Psychische Gesundheit
+49 931 201-76050

Sekretariat Tagesklinik
+49 931 250-8040

Prof. Dr. Marcel Romanos
+49 931 201-78000

Stellvertretende Direktion
PD Dr. Regina Taurines
+49 931 201-78010


Direktion / Prof. Dr. Marcel Romanos

PD Dr. Regina Taurines


+49 931 201-78040

+49 931 201-78620


Klinik und Poliklinik für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie des Universitätsklinikums | Margarete-Höppel-Platz 1 | 97080 Würzburg | Deutschland