Publications of CRC 1525

 

Publications 2025

Altieri D, Lorenz K, Epelman S (2025)
New Minimally Invasive Myocardial Ischemia/Reperfusion Approach
Circ Res. 2025 May 9;136(10):1110-1112.
Go to Publication

Aksentijevic D, Sedej S, Fauconnier J, Paillard M, Abdellatif M, Streckfuss-Bömeke K, Ventura-Clapier R, van der Velden J, de Boer RA, Bertero E, Dudek J, Sequeira V, Maack C (2025)
Mechano-energetic uncoupling in heart failure.
Nat Rev Cardiol. 2025 Oct; 22(10):773-797
Go to Publication

Ashour D, Appel M, Melika ET, Arampatzi P, Bischler T, Popiolkowski L, Hofmann U, Frantz S, Ramos GC (2025)
Immune reponses following myocardial infarction in aged mice.
In revision

Brand T, Baumgarten BT, Denzinger S, Reinders Y, Kleindl M, Schanbacher C, Funk F, Gedik N, Jabbasseh M, Kleinbongard P, Dudek J, Szendroedi J, Tolstik E, Schuh K, Krüger M, Dobrev D, Cuello F, Sickmann A, Schmitt JP, Lorenz K (2025)
From Ca2+dysregulation to heart failure: β-adrenoceptor activation by RKIP postpones molecular damages and subsequent cardiac dysfunction in mice carrying mutant PLNR9C by correction of aberrant Ca2+-handling.
Pharmacol Res. 2025 Jan; 211:107558
Go to Publication

Beyersdorf N, Afshar B, Pelin D, Bauser M, Kaiser E, Lamers J, Pätkau J, Heil M, Göpfert D, Hepp H, Al Hassan W, Kerkau T, Kerwagen F, Jahns R, Boivin-Jahns V, Frantz S, Ramos G, Hofmann U, Störk S, Morbach C (2025)
Cardioimmunologic response patterns after an acute heart failure event: Design & first results of AHF-Immunomonitoring
ESC Heart Fail 2025 Oct 30
Go to Publication

Dapergola E, Sustic M, Ashour D, Saliba E, Hofmann U, Frantz S, Ramos GC, Gasteiger G (2025)
Cytomegalovirus infection induces cardiac inflammation and exacerbates adverse tissue remodeling after myocardial infarction.
In submission

Ehlers G, Todtmann AM, Holsten L, Willers M, Heckmann J, Schoning J, Richter M, Heinemann AS, Pirr S, Heinz A, Dopfer C, Handler K, Becker M, Buchel J, Wockel A, von Kaisenberg C, Hansen G, Hiller K, Schultze JL, Hartel C, Kastenmuller W, Vaeth M, Ulas T, Viemann D (2025)
Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth.
Nature Communications; 16
Go to Publication 

Freitag A, Günther K, Campillo Prados M, Hochrein SM, Schmitz W, Sinning K, Zischinsky G, Klebl B, Ohlsen K, Morschhäuser J, Werz O, Jordan PM, Vaeth M (2025)
Glucose Metabolism Controls Oxidative Burst and Lipid Mediator Production in Neutrophils upon Microbial Challenge.
Go to Publication

Göb V, Zimmermann L, Hemmen K, Haarmann A, Heinze KG, Schuhmann MK, Stegner D (2025)
Platelet-Derived PDGF-A Disrupts Blood-Brain Barrier Integrity in Ischemic Stroke.
Arteriosclerosis, Thrombosis, and Vascular Biology 45(7)
Go to Publication

Grune J, Bajpai G, Ocak PT, Kaufmann E, Mentkowski K, Pabel S, Kumowski N, Pulous FE, Tran KA, Rohde D, Zhang S, Iwamoto Y, Wojtkiewicz GR, Vinegoni C, Green U, Swirski FK, Stone JR, Lennerz JK, Divangahi M, Hulsmans M, Nahrendorf M (2025)
Virus-Induced Acute Respiratory Distress Syndrome Causes Cardiomyopathy Through Eliciting Inflammatory Responses in the Heart.
Circulation; 150(1)
Go to Publication

Hackenbroch C, Cimen T, Gross C, Rubenzucker S, Burkard P, Groß N, Ahrends R, Girbl T, Stegner D (2025)
Neutrophil recruitment depends on platelet-derived leukotriene B4.
Blood Adv 2025; 9(9): 2226–2230
Go to Publication

Hanns P, Colpaert R, Castellanos-Martinez R, Weidner F, Beensen S, Matthias F, Xu L, Kuster GM, Schinner C (2025) 
Screening for pro-adhesive compounds and their relevance as therapeutic approach in Arrhythmogenic Cardiomyopathy.
bioRxiv
Go to Publication

Heron C, Lemarcis T, Laguerre O, Bundalo M, Valentin C, Valet M, Dumesnil A, Michel J, Mulder P, Zernecke A, Tardif V, Brakenhielm E (2025)
Blocking Interleukin-1β transiently limits left ventricular dilation and reduces cardiac lymphangiogenesis during pressure-overload in mice.
bioRxiv
Go to Publication

Hulsmans M, Schloss MJ, Lee IH, Bapat A, Iwamoto Y, Vinegoni C, Paccalet A, Yamazoe M, Grune J, Pabel S, Momin N, Seung H, Kumowski N, Pulous FE, Keller D, Bening C, Green U, Lennerz JK, Mitchell RN, Lewis A, Casadei B, Iborra-Egea O, Bayes-Genis A, Sossalla S, Ong CS, Pierson RN, Aster JC, Rohde D, Wojtkiewicz GR, Weissleder R, Swirski FK, Tellides G, Tolis G Jr, Melnitchouk S, Milan DJ, Ellinor PT, Naxerova K, Nahrendorf M. (2025)
Recruited macrophages elicit atrial fibrillation.
Science 2023 Jul 13; 381(6654):231-239
Go to Publication

Kumowski N, Pabel S, Grune J, Momin N, Ninh VK, Stengel L, Mentkowski KI, Iwamoto Y, Zheng Y, Lee I, Matthias J, Wirth JO, Pulous FE, Seung H, Paccalet A, Muse CG, Ting KKY, Delgado P, Lewis AJM, Kaushal V, Kreso A, Brown D, Hayat S, Kramann R, Swirski FK, Naxerova K, Propheter DC, Hooper LV, Moskowitz MA, King KR, Rosenthal N, Hulsmans M, Nahrendorf M (2025)
Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia.
Science 2025 Sep 4; 89(6764):1043-1048
Go to Publication

Kusch C*, Stegner D*, Johnson D, Nurden P, Burkard P, Bergmeier W, Onursal C, Navarro S, Hackenbroch C, Meub M, Gross Ca, Weiss LJ, Schenk J, Bender M, Andres O, Kastenmüller W, Heinze KG, Sauer M, Schulze H, Ley K, Nurden AT, Nieswandt B (2025)
Platelet-derived Integrin and Tetraspanin-enriched Tethers Exacerbate Severe Inflammation.
in revision

Liberale L, Tual-Chalot S, Sedej S, Ministrini S, Georgiopoulos G, Grunewald M, Bäck M, Bochaton-Piallat ML, Boon RA, Ramos GC, de Winther MPJ, Drosatos K, Evans PC, Ferguson JF, Forslund-Startceva SK, Goettsch C, Giacca M, Haendeler J, Kallikourdis M, Ketelhuth DFJ, Koenen RR, Lacolley P, Lutgens E, Maffia P, Miwa S, Monaco C, Montecucco F, Norata GD, Osto E, Richardson GD, Riksen NP, Soehnlein O, Spyridopoulos I, Van Linthout S, Vilahur G, Wentzel JJ, Andrés V, Badimon L, Benetos A, Binder CJ, Brandes RP, Crea F, Furman D, Gorbunova V, Guzik TJ, Hill JA, Lüscher TF, Mittelbrunn M, Nencioni A, Netea MG, Passos JF, Stamatelopoulos KS, Tavernarakis N, Ungvari Z, Wu JC, Kirkland JL, Camici GG, Dimmeler S, Kroemer G, Abdellatif M, Stellos K (2025)
Roadmap for alleviating the manifestations of ageing in the cardiovascular system.
Nature Reviews Cardiology 2025; 22:577–605
Go to Publication

Maack C, Dudek J, Bertero E, Tampakakis E, Vernon HJ (2025)
Mitochondrial cardiomyopathies: pathogenesis, diagnosis, and treatment.
European Heart Journal, 2025 October 21; 46(40):4060–4075
Go to Publication

Melika ET, Ashour D, Kyoungmin K, Nickel A, Hofmann U, Arias-Loza P, Chen X, Higuchi T, Maack C, Frantz S, Karlstaedt A, Ramos GC (2025)
Interferon gamma signaling drives cardiac metabolic rewiring.
In submission

Müller M, Schubert T, Welke C, Maske T, Patschkowski T, Donhauser E, Heinen-Weiler J, Hormann FL, Heiles S, Schulz TJ, Lengenfelder LA, Landwehrjohann L, Vogt ET, Stratmann B, Hense J, Lüdtke S, Düfer M, Tolstik E, Dierks J, Lorenz K, Huxohl T, Reil JC, Sequeira V, Schopfer FJ, Freeman BA, Rudolph V, Schlomann U, Klinke A. (2025)
Nitro-oleic acid enhances mitochondrial metabolism and ameliorates heart failure with preserved ejection fraction in mice.
Nat Commun. 2025 Apr 26; 16(1):3933.
Go to Publication

Nahrendorf M, Ginhoux F, Swirski FK (2025)
Immune system influence on physiology.
Science 2025 Aug 7; 389(6760):594-59
Go to Publication

Nieswandt B, Stegner D, Navarro S (2025)
EMA601 and glenzocimab: two glycoprotein VI inhibitory Fabs with different potency.
Go to Publication

Pepin ME, Konrad PJM, Nazir S, Bazgir F, Maack C, Nickel A, Gorman JM, Hohl M, Schreiter F, Dewenter M, de Britto Chaves Filho A, Schulze A, Karlstaedt A, Frey N, Seidman CE, Seidman JG, Backs J (2025)
Mitochondrial NNT Promotes Diastolic Dysfunction in Cardiometabolic HFpEF.
Circ Res 2025 Jun 6; 136(12):1564-1578
Go to Publication

Rebs S, Sedaghat-Hamedani F, Kayvanpour E, Dudek J, Berecic B, Eberl H, Hubscher D, Reich C, Klein T, Doose S, Nikolaev VO, Guan K, Hasenfuss G, Sauer M, Tiburcy M, Maack C, Meder B§, Streckfuss-Bömeke K (2025)
RBM20-variants induce distinct calcium handling and metabolic phenotypes in patient-specific stem cell models of dilated and non-compaction cardiomyopathy.
Go to Publication

Rizakou A†, Bauer M†, Delgobo M, Hofmann A, Heinrichs M, Reiter T, Werner R, Saliba AE, Jahns R, Jahns V, Nikolaev VO, Mariotti-Ferrandiz E, Ashour D, Frantz S§, Campos Ramos G (2025)
Characterization of ADRB1-specific TCR motifs in patients with myocardial infarction.
Go to Publication

Rizakou A, Bauer M, Delgobo M, Hofmann A, Heinrichs M, Siegel J, Krammer T, Saliba AE, Gouge KL, Jahns R, Boivin-Jahns V, Nikolaev V, Hofmann U, Mariotti-Ferrandiz E, Ashour D, Frantz S, Ramos GC (2025)
Tracking antigen-specific T cell responses in patients with myocardial infarction.
Go to Publication

Rizakou A, Rosa A, Sakalli E, Rizzo G, Burkard P, Arampatzi P, Beck S, Gundel S, Klapproth K, Bandi SR, Piollet M, Göb V, Stegner D, Zernecke A, Nieswandt B*, Cochain C (2025)
Platelets drive macrophage inflammatory activation in vitro.
J Leukoc Biol 2025 Aug 8; 117(8)
Go to Publication

Rizakou A, Weiss LJ, Sakalli ET, Giuseppe Rizzo, Beck S, Burkard P, Rosa A, Bandi SR, Piollet M, Göb V, Krammer T, Saliba AE, Stegner D, Zernecke A, Cochain C, Nieswandt B (2025)
Targeting the platelet GPIIbIIIa-GPVI axis minimally affect acute inflammation and cardiac repair in experimental permanent myocardial infarction.
Go to Publication

Schanbacher C, Goebeler M-E, Gerull B, Lorenz K
Targeting pathological ERK1/2 signaling in cancer and beyond.
Trends Mol Med . 2025 Sep 5
Go to Publication

Shing Fung Chan A, Greiner J, Brennan T, Agrawal A, Hemmer H, Sinning K, Marschhäuser L, Cheung WL, Iqbal Z, Klesen A, Seidel T, Vaeth M, Rog-Zielinska E, Kohl P, Schneider-Warme F and Grün D (2025)
Spatio-temporal dynamics of the fibrotic niche in cardiac repair.
BioRxiv 2024
Go to Publication

Siegel J, Beer D, Janjatovic S, Ashour D, Auer A, Zipp L, Kozuch E, Dudek J, Krammer T, Saliba AE, Cochain C, Störk S, Heuschmann P, Morbach C, Hofmann U, Frantz S, Wardemann H, Heinrichs M, Heinze KG, Streckfuss-Bömeke K, Ramos GC (2025)
Dissecting antibody responses to cardiac receptors in patients with myocardial infarction
Go to Publication

Sinning K, Hochrein SM, Gubert GF, Vaeth M (2025)
Metabolic Profiling of Activated T Lymphocytes Using Single-Cell Energetic Metabolism by Profiling Translation Inhibition.
Methods Mol Biol 2025; 2904:259-271
Go to Publication

Staudt S, Nikolka F, Perl M, Franz J, Leblay N, Yuan X-K, Larrayoz M, Lozano T, Warmuth L, Fante MA, Skorpskaite A, Fei T, Bromberg M, San Martin-Uriz P, Rodriguez-Madoz JR, Ziegler-Martin K, Adil-Gholam N, Benz P, Tran Huu P, Freitag F, Riester Z, Stein-Thoeringer C, Schmitt M, Kleigrewe K, Weber J, Mangold K, Ho P, Einsele H, Prosper F, Ellmeier W, Busch D, Visekruna A, Slingerland J, Shouval R, Hiller K, Lasarte JJ, Martinez-Climent JA, Pausch P, Neri P, van den Brink M, Poeck H, Hudecek M, Luu M (2025)
Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells.
bioRxiv
Go to Publication

Traub J, Schuhmann M, Hofmann U, Ramos G, Beyersdorf N, Frantz S, Stoerk S, Stoll G, Frey A (2025)
High interleukin-8 serum levels independently predict long-term all-cause mortality in chronic heart failure.
medRxiv
Go to Publication

Waschke J, Amagai M, Becker C, Delmar M, Duru F, Garrod DR, Gerull B, Green KJ, Hertl M, Kowalczyk AP, Niessen CM, Nusrat A, Schinner C, Schlegel N, Sivasankar S, Vielmuth F, Spindler V (2025)  
Meeting report – Alpine desmosome disease meeting 2024: advances and emerging topics in desmosomes and related diseases. 
J Cell Sci 2025; 138(2)
Go to Publication

Williams T, Groß R, Arias-Loza AP, Nordbeck P, Noerpel M, Cirnu A, Kimmel L, DiyaaEldin D, Ramos G, Waschke J, Higuchi T, Gerull B (2025)
Insights from [18F]-FDG PET Imaging in Jup-Associated Arrhythmogenic Cardiomyopathy.
J Am Heart Assoc. 2025; 13:e038331
Go to Publication

Wu H, Lu Y, Sun D, Miao Z, Chen S, Xia W, Chen Y, Yu Y, Zhang W, Chen W, Stegner D, Lo SH, Wen A (2025)
CircFUT8 promotes proplatelet formation by interacting with IGF2BP2 and stabilizing TNS1 mRNA in megakaryocytes.
Blood 2024; 144(Supplement 1):1166.
Go to Publication

Xu A, Weissman D, Ermer KJ, Bertero E, Federspiel JM, Stadler F, Grünler E, Tangos M, Zervou S, Waddingham MT, Pearson JT, Reil JC, Scholtz S, Dudek J, Kohlhaas M, Nickel A, Carrier L, Eschenhagen T, Michels M, Dos Remedios C, Lal S, Prates Roma L, Hamdani N, Kuster D, Falcão-Pires I, Johnson CN, Lygate CA, van der Velden J, Maack C, Sequeira V (2025)
Hypercontractility and Oxidative Stress Drive Creatine Kinase Dysfunction in Hypertrophic Cardiomyopathy.
In press

Zhao X, Hochrein S, Eckstein M, Wu H, Sinning K, Ermer KJ, Puhl S, Eilers M, Schmitz W, Stigloher C, Claypool SM, Maack C, Dudek J, Vaeth M (2025)
Tafazzin-Mediated Cardiolipin Remodeling Controls Metabolic Stress Response and Effector Function of Inflammatory T Cells.
bioRxiv
Go to Publication

 

In submission (*). † Shared authorship. § Shared senior authorship

Publications 2024

Agrawal A, Thomann S, Basu S, Grün D (2024)
NiCo identifies extrinsic drivers of cell state modulation by niche covariation analysis.
Nat Commun, 2024 Dec 5;15(1):10628
Go to Publication

Ascheid D, Baumann M, Pinnecker J, Friedrich M, Szi-Marton D, Medved C, Bundalo M, Ortmann V, Öztürk A, Nandigama R, Hemmen K, Ergün S, Zernecke A, Hirth M, Heinze KG§, Henke E§ (2024)
A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy.
Nat Commun. 2024 Apr 27;15(1):3599
Go to Publication

Ashour D, Le Gouge K, Rainer PP, Mariotti-Ferrandiz E, Ramos GC (2024)
Exploring T Cell Receptor Repertoires in Myocardial Diseases.
Circ Res. 2024 Jun 7;134(12):1808-1823
Go to Publication

Asquith NL, Carminita E, Camacho V, Rodriguez-Romera A, Stegner D, Freire D, Becker IC, Machlus KR, Khan A, Italiano JE Jr (2024)
The bone marrow is the primary site of thrombopoiesis.
Blood 2024; 143(3): 272-278
Go to Publication

Bielenberg M, Kurelic R, Frantz S, Nikolaev VO (2024)
A mini-review: phosphodiesterases in charge to balance intracellular cAMP during T-cell activation.
Front Immunol. 2024 Mar 8:15:1365484
Go to Publication

Brand T, Lukannek AK, Jahns V, Jahns R, Lorenz K (2024) 
From "contraindicated" to "first line" – Current mechanistic insights beyond canonical β-receptor signaling.
Current Opinion in Pharmacology, Volume 76, June 2024, 102458
Go to Publication

Bundalo M, Vorlova S, Ulrich J, Barbieri R, Richter L, Höna L, Egg M, Bock J, Schäfer S, Amézaga Solé N, Rosa A, Rizzo G, Cochain C, Kastenmüller W, Henke E, Skryabin BV, Rozhdestvensky TS, Wildgruber M, Lorenz M, Kuhn M, Zernecke A (2024)
Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis.
bioRxiv
Go to Publication

Cachorro E, Günscht M, Schubert M, Sadek MS, Siegert J, Dutt F, Bauermeister C, Quickert S, Berning H, Nowakowski F, Lämmle S, Firneburg R, Luo X, Künzel SR, Klapproth E, Mirtschink P, Mayr M, Dewenter M, Vettel C, Heijman J, Lorenz K, Guan K, El-Armouche A (2024)
TREM2 protects from atherosclerosis by limiting necrotic core formation.
Nat Cardiovasc Res. 2024 Mar;3(3):269-282
Go to Publication

Cachorro E, Günscht M, Schubert M, Sadek MS, Siegert J, Dutt F, Bauermeister C, Quickert S, Berning H, Nowakowski F, Lämmle S, Firneburg R, Luo X, Künzel SR, Klapproth E, Mirtschink P, Mayr M, Dewenter M, Vettel C, Heijman J, Lorenz K, Guan K, El-Armouche A, Wagner M, Kämmerer S. (2024)
CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2.
Circ Res. 2023 Feb 17;132(4):400-414
Go to Publication

Chan, ASF, Greiner, J, Brennan T, Agrawal A, Hemmer H, Sinning K, Marschhäuser L, Cheung JWL, Iqbal Z, Klesen A, Seidel T, Vaeth M, Rog-Zielinska E, Kohl P, Schneider-Warme F, Grün, D (2024) 
Spatio-temporal dynamics of the fibrotic niche in cardiac repair.
Go to Publication

Chen X, Werner R A, Koshino K, Nose N, Mühlig S, Rowe S P, Pomper M G, Lapa C, Decker M*, Higuchi T* (2024)
Molecular imaging-derived biomarker of cardiac nerve integrity - Introducing high NET affinity PET probe 18F-AF78.
Theranostics 2022, 12(9), 4446-4458
Go to Publication

Dreher N*, Dörrler A-L*, Kraus S, Higuchi T, Serfling SE, Samnick S, Einsele H, Grigoleit GU, Buck AK, Werner RA (2024)
C-X-C Motif Chemokine Receptor 4-Targeted Radioligand Therapy in Hematological Malignancies – Myeloablative Effects, Anti-Lymphoma Activity and Safety Profile.
Clin Nucl Med. 2024 Feb 1;49(2):146-151
Go to Publication

Dreher N, Hahner S, Fuss CT, Schlotelburg W, Hartrampf PE, Serfling SE, Schirbel A, Samnick S, Higuchi T, Weich A, Lapa C, Rosenwald A, Buck AK, Kircher S, Werner RA (2024)
CXCR4-directed PET/CT with [(68) Ga]Ga-pentixafor in solid tumors-a comprehensive analysis of imaging findings and comparison with histopathology.
Eur J Nucl Med Mol Imaging, 2024 Apr;51(5):1383-1394
Go to Publication

Fender J, Klöcker J, Boivin-Jahns V, Ravens U, Jahns R, Lorenz K (2024)
Cardiac glycosides-quo vaditis?-past, present, and future?
Naunyn Schmiedebergs Arch Pharmacol. 2024 Dec;397(12):9521-9531
Go to Publication

Geist D, Hönes GS, Grund SC, Pape J, Siemes D, Spangenberg P, Tolstik E, Dörr S, Spielmann N, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Mittag J, Engel DR, Führer D, Lorenz K, Moeller LC (2024)
Canonical and Noncanonical Contribution of Thyroid Hormone Receptor Isoforms Alpha and Beta to Cardiac Hypertrophy and Heart Rate in Male Mice.
Thyroid. 2024 Jun;34(6):785-795
Go to Publication

Hilgendorf I, Frantz S, Frangogiannis NG (2024)
Repair of the Infarcted Heart: Cellular Effectors, Molecular Mechanisms and Therapeutic Opportunities.
Circ Res. 2024 Jun 7;134(12):1718-1751
Go to Publication

Janz A, Walz K, Cirnu A, Surjanto J, Urlaub D, Leskien M, Kohlhaas M, Nickel A, Brand T, Nose N, Wörsdörfer P, Wagner N, Higuchi T, Maack C, Dudek J, Lorenz K, Klopocki E, Ergün S, Duff HJ, Gerull B (2024)
Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes.
Mol Metab. 2024 Jan;79:101859
Go to Publication

Kammerer J, Cirnu A, Williams T, Hasselmeier M, Nörpel M, Chen R, Gerull B (2024)
Macro-based collagen quantification and segmentation in picrosirius red-stained heart sections using light microscopy.
Biol Methods Protoc. 2024 Apr 27;9(1):bpae027
Go to Publication

Kerp H, Gassen J, Grund SC, Hönes GS, Dörr S, Mittag J, Härting N, Kaiser F, Moeller LC, Lorenz K§, Führer D§ (2024)
Cardiac recovery from pressure overload is not altered by thyroid hormone status in old mice. 
Front Endocrinol (Lausanne) 2024 Feb 22;15:1339741
Go to Publication

Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, Künzel SR, Kämmerer S, Günscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L, Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M, El-Armouche A (2024)
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
Nat Commun. 2022 Dec 10;13(1):7648
Go to Publication

Kohlhaas M, Sequeira V, Parikh S, Dietl A, Richter O, Bay J, Bertero E, Schwemmlein J, Tian Q, Friedrich FW, Flenner F, Nickel AG, Alscher F, Nanadikar MS, Venkataraman R, Baudenbacher FJ, Kappl R, Johnson V, Roma LP, Kasakow A, Hohl M, Laufs U, Hoth M, Katschinski DM, Böhm M, Lipp P, Carrier L, Eschenhagen T, Knollmann BC, Maack C. (2024) 
Mitochondrial reactive oxygen species cause arrhythmias in hypertrophic cardiomyopathy.
Go to Publication

Kolczyńska-Matysiak K, Karwen T, Loeffler M, Hawro I, Kassouf T, Stegner D, Sumara G. (2024)
Dense but not alpha granules of platelets are required for insulin secretion from pancreatic β cells.
BBRC, Volume 734, 19 November 2024:150753
Go to Publication

Kollmann A, Lohr D, Ankenbrand MJ, Bille M, Terekhov M, Hock M, Elabyad I, Baltes S, Reiter T, Schnitter F, Bauer WR, Hofmann U, Schreiber LM (2024)
Cardiac function in a large animal model of myocardial infarction at 7 T: deep learning based automatic segmentation increases reproducibility.
BBRC, 2024 May 14;14(1):11009
Go to Publication

Lavillegrand JR, Al-Rifai R, Thietart S, Guyon T, Vandestienne M, Cohen R, Duval V, Zhong X, Yen D, Ozturk M, Negishi Y, Konkel J, Pinteaux E, Lenoir O, Vilar J, Laurans L, Esposito B, Bredon M, Sokol H, Diedisheim M, Saliba AE, Zernecke A, Cochain C, Haub J, Tedgui A, Speck NA, Taleb S, Mhlanga MM, Schlitzer A, Riksen NP, Ait-Oufella H (2024)
Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming.
Nature. 2024 Oct;634(8033):447-456
Go to Publication

Li Y, Díaz I, Martín-Valls G, Beyersdorf N and Mateu E (2024)
Systemic CD4 cytotoxic T cells improve protection against PRRSV-1 transplacental infection.
Front Immunol. 2023; 13:1020227
Go to Publication

Liebich A, Bundschuh RA, Pfob CH, Kircher M, Wienand G, Raake P, Nekolla SG, Schottelius M, Higuchi T, Rieger M, Lapa C (2024) 
(99m)Tc]-PentixaTec SPECT/CT for Imaging of Chemokine Receptor 4 Expression After Myocardial Infarction.
Circ Cardiovasc Imaging, 2024 Nov;17(11):e016992
Go to Publication

Lohr D, Kollmann A, Bille M, Terekhov M, Elabyad I, Hock M, Baltes S, Reiter T, Schnitter F, Bauer WR, Hofmann U, Schreiber LM (2024)
Precision imaging of cardiac function and scar size in acute and chronic porcine myocardial infarction using ultrahigh-field MRI.
Commun Med (Lond). 2024 Jul 18;4(1):146.*
Go to Publication

Navarro S, Talucci I, Göb V, Hartmann S, Beck S, Orth V, Stoll G, Maric HM, Stegner D, Nieswandt B (2024)
The humanized platelet glycoprotein VI Fab inhibitor EMA601 protects from arterial thrombosis and ischaemic stroke in mice.
Eur Heart J. 45(43):4582-4597
Go to Publication

Navarro S, Vögtle T, Groß N, Preu J, Englert M, Nieswandt B, Bösl MR, Stegner D. (2024) 
Mutations of the dimerization site of glycoprotein (GP) VI result in abolished expression.
Thrombosis Research, Volume 232, December 2023:89-92
Go to Publication

Piollet M, Porsch F, Rizzo G, Kapser F, Schulz DJJ, Kiss MG, Schlepckow K, Morenas-Rodriguez E, Sen MO, Gropper J, Bandi SR, Schäfer S, Krammer T, Leipold AM, Hoke M, Ozsvár-Kozma M, Beneš H, Schillinger M, Minar E, Roesch M, Göderle L, Hladik A, Knapp S, Colonna M, Martini R, Saliba AE, Haass C, Zernecke A#+, Binder CJ#+, Cochain C (2024)
TREM2 protects from atherosclerosis by limiting necrotic core formation.
Go to Publication

Raabe J, Wittig I, Laurette P, Stathopoulou K, Brand T, Schulze T, Klampe B, Orthey E, Cabrera-Orefice A, Meisterknecht J, Thiemann E, Laufer SD, Shibamiya A, Reinsch M, Fuchs S, Kaiser J, Yang J, Zehr S, Wrona KM, Lorenz K, Lukowski R, Hansen A, Gilsbach R, Brandes RP, Ulmer BM, Eschenhagen T, Cuello F.  (2024)
Physioxia rewires mitochondrial complex composition to protect stem cell viability.
Redox Biology, Volume 77, November 2024:103352
Go to Publication

Reyat JS, Sommerfeld LC, O'Reilly M, Roth Cardoso V, Thiemann E, Khan AO, O'Shea C, Harder S, Müller C, Barlow J, Stapley RJ, Chua W, Kabir SN, Grech O, Hummel O, Hübner N, Kääb S, Mont L, Hatem SN, Winters J, Zeemering S, Morgan NV, Rayes J, Gehmlich K, Stoll M, Brand T, Schweizer M, Piasecki A, Schotten U, Gkoutos GV, Lorenz K, Cuello F, Kirchhof P, Fabritz L (2024)
PITX2 deficiency leads to atrial mitochondrial dysfunction.
Cardiovasc Res. 2024 Dec 4;120(15):1907-1923
Go to Publication

Richter L, Bauer M, Bernsen C, Vogel E, Mahmud Z, Saliba AE, Schulz R, Frantz S, Ashour D, Ramos GC (2024)
Identification of a novel myosin antigen activating CD8+ T cells in C57BL/6 mice.
bioRxiv; 2024.
Go to Publication

Rodríguez-Soacha D A, Steinmüller S A M, Isbilir A, Fender J, Deventer M H, Ramirez Y, Tutov A, Sotriffer C, Stove C P, Lorenz K, Lohse M, Hislop J, Decker M* (2024)
Development of an indole-amide-based photopharmacological tool compound acting as a selective cannabinoid receptor subtype 1 “cis-on” agonist.
ACS Chem. Neurosci. 2022, 13(16):2410-2435
Go to Publication

Schäfer S, Gogiraju R, Rösch M, Kerstan Y, Beck L, Garbisch J, Saliba AE, Gisterå A, Hermanns HM, Boon L, Kastenmüller W, Schäfer K, Cochain C, Zernecke A (2024)
CD8+ T Cells Drive Plaque Smooth Muscle Cell Dedifferentiation in Experimental Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2024 44(8):1852-1872
Go to Publication

Schnitter F, Stangl F, Noeske E, Bille M, Stadtmüller A, Vogt N, Sicklinger F, Leuschner F, Frey A, Schreiber L, Frantz S, Beyersdorf N, Ramos G, Gladow N, Hofmann U (2024)
Characterizing the immune response to myocardial infarction in pigs.
Basic Res Cardiol. 2024; 119(3):453-479
Go to Publication/a>

Schorr K, Chen X, Sasaki T, Arias-Loza AP, Lang J, Higuchi T, Goepferich A. (2024) 
Rethinking Thin-Layer Chromatography for Screening Technetium-99m Radiolabeled Polymer Nanoparticles.
ACS Pharmacol Transl Sci, 2024 Aug 30;7(9):2604-2611
Go to Publication

Sink A, Gerwe H, Hübner H, Boivin-Jahns V, Fender J, Lorenz K, Gmeiner P, Decker M* (2024)
Photo-Adrenalines: b2-Adrenergic receptor agonists as molecular probes for the study of spatiotemporal adrenergic signaling”.
Chem. Eur. J. 2024
Go to Publication

Spatz P, Chen X, Reichau K, Huber ME, Mühlig S, Matsusaka Y, Schiedel M, Higuchi T, Decker M (2024)
Development and Initial Characterization of the First 18F-CXCR2-Targeting Radiotracer for PET Imaging of Neutrophils.
J Med Chem 2024 Apr 25;67(8):6327-6343
Go to Publication

Staudt S, Nikolka F, Perl M, Franz J, Leblay N, Yuan X, Warmuth L, Fante MA, Skorpskaite A, Fei T, Bromberg Maria, San Martin-Uriz P, Rodriguez-Madoz JR, Ziegler-Martin K, Adil Gholam N, Benz P, Tran Huu P, Stein-Thoeringer C, Schmitt M, Kleigrewe K, Freitag F, Riester R, Weber J, Mangold K, Einsele H, Prosper P, Ellmeier W, Busch D, Visekruna V, Slingerland J, Shouval R, Hiller H, van den Brink M, Pausch P, Neri P, Hudecek M, Poeck H, Luu M+ (2024)
Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells.
bioRxiv
Go to Publication

Steinmüller S A M, Fender J, Deventer M H, Tutov A, Lorenz K, Stove C P, Hislop J N, Decker M* (2024)
Visible light photoswitchable benzimidazole azo-arenes as β-arrestin2-biased selective cannabinoid 2 receptor agonists.
Angew. Chem. Int. Ed. 2023, 62(49), e202306176 – selected for frontispiece picture
Go to Publication

Tolstik E, Lehnart SE, Soeller C, Lorenz K, Sacconi L. (2024)
Cardiac multiscale bioimaging: from nano- through micro- to mesoscales.
Trends Biotechnol. 2024 Feb;42(2):212-227
Go to Publication

Torcellan T, Friedrich C, Doucet-Ladevèze R, Ossner T, Solé VV, Riedmann S, Ugur M, Imdahl F, Rosshart SP, Arnold SJ, Gomez de Agüero M, Gagliani N, Flavell RA, Backes S, Kastenmüller W, Gasteiger G. (2024) 
Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection.
Immunity
Immunity, 2024 Jan 9;57(1):124-140.e7
Go to Publication

Traub J, Beyersdorf N, Sell R, Frantz S, Störk S, Stoll G, Frey A (2025)
Plasma levels of sTREM2 in chronic heart failure: predictors and prognostic relevance.
Am J Physiol Heart Circ Physiol, 328(3):H594-H602
Go to Publication

Traub J, Hettesheimer D, Pinter J, Sahitim F, Fette G, Henneges C, Morbach C, Herrmann S, Puppe F, Frey A, Störk S, Christa M (2024)
Spontaneous echo contrast in the left atrial appendage is linked to a higher risk of thromboembolic events and mortality in patients with atrial fibrillation.
Int J Cardiol Heart Vasc, 56:101590
Go to Publication

Traub J, Homola G, Morbach C, Sell R, Göpfert D, Frantz S, Pham M, Stoll G, Störk S, Frey, A (2024)
Long-term cognitive and brain morphologic changes in chronic heart failure: Results of the Cognition. Matters-HF study.
ESC Heart Fail, 11(5):3191-3199
Go to Publication

Traub J, Otto M, Monoranu C M , Oeckl  P, Homola G, Radaković D, Pham M, Störk S, Stoll G, Frey, A (2024)
Increasing Phosphorylated Tau Protein Serum Levels in the Course of Chronic Heart Failure.
JACC Heart Fail, 12(8), 1494-1496
Go to Publication

Traub J, Schürmann P, Schmitt D, Gassenmaier T, Fette G, Frantz S, Störk S, Beyersdorf N, Boivin-Jahns V, Jahns R, Hofmann U, Frey A
Features of metabolic syndrome and inflammation independently affect left ventricular function early after first myocardial infarction
Int J Cardiol. 2023;370:43-50
Go to Publication

Traub J, Schuhmann M K, Sell R, Frantz S, Störk S, Stoll G, Frey A (2024)
S100B Serum Levels in Chronic Heart Failure Patients: A Multifaceted Biomarker Linking Cardiac and Cognitive Dysfunction. 
Int J Mol Sci, 25(16):9094
Go to Publication

Tutov A, Chen X, Werner R A, Mühlig S, Zimmermann T, Nose N, Koshino K, Lapa C, Decker M*, Higuchi T* (2024)
Rationalizing binding modes of radiotracers targeting norepinephrine transporter after initial translational studies
Pharmaceutics 2023, 15(2):690
Go to Publication

Wagenhäuser I, Almanzar G, Förg F B, Stein A, Eiter I, Reusch J, Mees J, Herzog A, Vogel U, Frey A, Lâm T T, Schubert-Unkmeir A, Dölken L, Kurzai O, Frantz S, Gabel A, Petri N, Prelog M, Krone M. (2024)
Heterologous and homologous COVID-19 mRNA vaccination schemes for induction of basic immunity show similar immunogenicity regarding long-term spike-specific cellular immunity in healthcare workers.
Vaccine, 42(21):126132
Go to Publication

Weissman D, Dudek J, Sequeira V, Maack C. (2024) 
Fabry Disease: Cardiac Implications and Molecular Mechanisms.
Curr Heart Fail Rep, 2024 Apr;21(2):81-100
Go to Publication

Werner F, Naruke T, Sülzenbrück L, Schäfer S, Rösch M, Völker K, Krebes L, Abeßer M, Möllmann D, Baba HA, Schweda F, Zernecke A, Kuhn (2024)
Auto/Paracrine C-Type Natriuretic Peptide/Cyclic GMP Signaling Prevents Endothelial Dysfunction. 
Int J Mol Sci, 25(14):7800
Go to Publication

Zhang Y, Vandestienne M, Lavillegrand JR, Joffre J, Santos-Zas I, Lavelle A, Zhong X, Le Goff W, Guérin M, Al-Rifai R, Laurans L, Bruneval P, Guérin C, Diedisheim M, Migaud M, Puel A, Lanternier F, Casanova JL, Cochain C, Zernecke A, Saliba AE, Mokry M, Silvestre JS, Tedgui A, Mallat Z, Taleb S, Lenoir O, Vindis C, Camus SM, Sokol H, Ait-Oufella H (2024)
Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy
Nat Commun. 2023 Aug 1;14(1):4622
ZGo to Publication

In submission (*). † Shared authorship. § Shared senior authorship

Publications 2023

Ashour DE, Rebs S, Arampatzi P, Saliba AE, Dudek J, Schulz R, Hofmann U, Frantz S, Cochain C, Streckfuß-Bömeke, Ramos GC (2023)
An interferon gamma response signature links myocardial aging and immunosenescence.
Cardiovasc Res.;119(14):2458-2468
Go to Publication

Bazgir F, Nau J, Nakhaei-Rad S, Amin E, Wolf MJ, Saucerman JJ, Lorenz K, Ahmadian MR (2023)
The Microenvironment of the Pathogenesis of Cardiac Hypertrophy.
Cells. 2023 Jul 4;12(13):1780
Go to Publication

Beck S, Öftering P, Li R, Hemmen K, Nagy M, Wang Y, Zarpellon A, Schuhmann MK, Stoll G, Ruggeri ZM, Heinze KG, Heemskerk JWM, Ruf W, Stegner D, Nieswandt B (2023)
Platelet glycoprotein V spatio-temporally controls fibrin formation.
Nat Cardiovasc Res. 2023 Apr;2(4):368-382
ZGo to Publication

Buck AK, Grigoleit GU, Kraus S, Schirbel A, Heinsch M, Dreher N, Higuchi T, Lapa C, Hänscheid H, Samnick S, Einsele H, Serfling SE, Werner RA (2023)
C-X-C Motif Chemokine Receptor 4-Targeted Radioligand Therapy in Patients with Advanced T-Cell Lymphoma.
The Journal of Nuclear Medicine (JNM) 2023 Jan; 64(1): 34-39
Go to Publication

Buck AK, Serfling SE, Kraus S, Samnick S, Dreher N, Higuchi T, Rasche L, Einsele H, Werner RA (2023)
Theranostics in Hematooncology
J Nucl Med. 2023 Jun 8:jnumed.122.265199
Go to Publication

Cachorro E, Günscht M, Schubert M, Sadek MS, Siegert J, Dutt F, Bauermeister C, Quickert S, Berning H, Nowakowski F, Lämmle S, Firneburg R, Luo X, Künzel SR, Klapproth E, Mirtschink P, Mayr M, Dewenter M, Vettel C, Heijman J, Lorenz K, Guan K, El-Armouche A, Wagner M, Kämmerer S (2023)
CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2.
Circ Res. 2023 Feb 17;132(4):400-414
Go to Publication

Campos Ramos G, Hudecek M (2023)
The era of in vivo T cell engineering
Med. 2022 Feb 11;3(2):85-86
Go to Publication

Chen R, Buchmann S, Kroth A, Arias-Loza AP, Kohlhaas M, Wagner N, Grüner G, Nickel A, Cirnu A, Williams T, Maack C, Ergün S, Frantz S, Gerull B (2023)
Mechanistic Insights of the LEMD2 p.L13R Mutation and Its Role in Cardiomyopathy
Circ Res. 2023 Jan 20;132(2):e43-e58.
Go to Publication

Chen Z, Väth M, Eckstein M, Delgobo M, Ramos G, Frantz S, Hofmann U, Gladow N (2023)
Characterization of the effect of the GLUT-1 inhibitor BAY-876 on T cells and macrophages.
Eur J Pharmacol. 2023 Feb 2;175552
Go to Publication

Chowdhury A, Boshnakovska A, Aich A, Methi A, Vergel Leon AM, Silbern I, Lüchtenborg C, Cyganek L, Prochazka J, Sedlacek R, Lindovsky J, Wachs D, Nichtova Z, Zudova D, Koubkova G, Fischer A, Urlaub H, Brügger B, Katschinski DM, Dudek J, Rehling P (2023)
Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome
EMBO Mol Med 15(9):e17399
Go to Publication

de Jonckheere B, Kollotzek F, Münzer P, Göb V, Fischer M, Mott K, Coman C, Troppmair NN, Manke MC, Zdanyte M, Harm T, Sigle M, Kopczynski D, Bileck A, Gerner C, Hoffmann N, Heinzmann D, Assinger A, Gawaz M, Stegner D, Schulze H, Borst O*, Ahrends R (2023)
Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation.
Nat Cardiovasc Res 2023; 2: 835-852
Go to Publication

Delgobo M, Weiß E, Ashour D, Richter L, Popiolkowski L, Arampatzi P, Stangl V, Arias-Loza P, Mariotti-Ferrandiz E, Rainer PP, Saliba AE, Ludewig B, Hofmann U, Frantz S and Campos Ramos G (2023)
Myocardial Milieu Favors Local Differentiation of Regulatory T Cells
Circulation Research. 2023;132:565–582
Go to Publication

Dolejsi T, Delgobo M, Schuetz T, Tortola L, Heinze KG, Hofmann U, Frantz S, Bauer A, Ruschitzka F, Penninger JM, Campos Ramos G, Haubner BJ (2023)
Adult T-cells impair neonatal cardiac regeneration.
Eur Heart J. 2022 Jul 21;43(28):2698-2709
Go to Publication

Hapke N, Heinrichs M, Ashour D, Vogel E, Hofmann U, Frantz S, Campos Ramos G (2023)
Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarction
J Mol Cell Cardiol. 2022 Dec;173:25-29
Go to Publication

Hartrampf PE, Kosmala A, Serfling SE, Bundschuh L, Higuchi T, Lapa C, Rowe SP, Matsusaka Y, Weich A, Buck AK, Bundschuh RA, Werner RA (2023)
Interobserver Agreement Rates on C-X-C Motif Chemokine Receptor 4-Directed Molecular Imaging and Therapy.
Clin Nucl Med. 2023 Mar 22
Go to Publication

Higuchi T, Hartrampf PE, Buck AK, Pomper MG, Rowe SP, Serfling SE, Werner RA (2023)
Role of Functional SPECT and PET in Renal Emergencies
Semin Nucl Med. 2023 May 24:S0001-2998(23)00031-4
Go to Publication

Higuchi T, Werner RA (2023)
Unfolding the cardioprotective potential of sigma-1 receptor-directed molecular imaging
J Nucl Cardiol. 2023 Apr;30(2):662-664
Go to Publication

Hulsmans M, Schloss MJ, Lee IH, Bapat A, Iwamoto Y, Vinegoni C, Paccalet A, Yamazoe M, Grune J, Pabel S, Momin N, Seung H, Kumowski N, Pulous FE, Keller D, Bening C, Green U, Lennerz JK, Mitchell RN, Lewis A, Casadei B, Iborra-Egea O, Bayes-Genis A, Sossalla S, Ong CS, Pierson RN, Aster JC, Rohde D, Wojtkiewicz GR, Weissleder R, Swirski FK, Tellides G, Tolis G, Jr., Melnitchouk S, Milan DJ, Ellinor PT, Naxerova K, Nahrendorf M. (2023) 
Recruited macrophages elicit atrial fibrillation.
Sci Immunol. 2023 Nov 24;8(89):eadj5789
Go to Publication

Göpfert D, Traub J, Sell R, Homola GA, Vogt M, Pham M, Frantz S, Störk S, Stoll G, Frey A (2023)
Profiles of cognitive impairment in chronic heart failure-A cluster analytic approach
Front Hum Neurosci. 2023 Apr 20
Go to Publication

Janz A, Walz K, Cirnu A, Surjanto J, Urlaub D, Leskien M, Kohlhaas M, Nickel A, Brand T, Nose N, Wörsdörfer P, Wagner N, Higuchi T, Maack C, Dudek J, Lorenz K, Klopocki E, Ergün S, Duff HJ, Gerull B (2023)
Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes
Mol Metab.:101859
Go to Publication

Kaminski A, Hager FT, Kopplin L, Ticconi F, Leufgen A, Vendelova E, Rüttger L, Gasteiger G, Cerovic V, Kastenmüller W, Pabst O, Ugur M. (2023)
Resident regulatory T cells reflect the immune history of individual lymph nodes.
Sci Immunol 2023 Nov 24; 8(89)
Go to Publication

Klingenberg R, Holtkamp F, Grün D, Frey A, Jahns V, Jahns R, Gassenmaier T, Hamm CW, Frantz S, Keller T (2023)
Use of serial changes in biomarkers vs. baseline levels to predict left ventricular remodelling after STEMI.
ESC Heart Failure 2023 Feb; 10(1): 432-441
Go to Publication

Kosmala A, Seifert S, Schneid S, Dreher N, Higuchi T, Weich A, Serfling SE, Hartrampf PE, Einsele H, Buck AK, Topp MS, Duell J, Werner RA (2023)
Lymphoma-Sink Effect in Marginal Zone Lymphoma Based on CXCR4-Targeted Molecular Imaging
Mol Imaging Biol. 2023 Jun 7
Go to Publication

Kosmala A, Serfling SE, Michalski K, Lindner T, Schirbel A, Higuchi T, Hartrampf PE, Derlin T, Buck AK, Weich A, Werner RA (2023)
Molecular imaging of arterial fibroblast activation protein: association with calcified plaque burden and cardiovascular risk factors
Eur J Nucl Med Mol Imaging. 2023 May 6
Go to Publication

Kosmala A, Serfling SE, Schlötelburg W, Lindner T, Michalski K, Schirbel A, Higuchi T, Hartrampf PE, Buck AK, Weich A, Werner RA (2023)
High Interobserver Agreement on PSMA PET/CT Even in the Absence of Clinical Data.
Clin Nucl Med. 2023 Mar 1;48(3):207-212.
Go to Publication

Kosmala A, Serfling SE, Schlötelburg W, Lindner T, Michalski K, Schirbel A, Higuchi T, Hartrampf PE, Buck AK, Weich A, Werner RA (2023)
Impact of 68 Ga-FAPI-04 PET/CT on Staging and Therapeutic Management in Patients with Digestive System Tumors.
Clinical Nuclear Medicine 2023 Jan 1; 48(1): 35-42
Go to Publication

Krause J, Nickel A, Madsen A, Aitken-Buck HM, Stoter A M S, Schrapers J, Ojeda F, Geiger K, Kern M, Kohlhaas M, Bertero E, Hofmockel P, Hübner F, Assum I, Heinig M, Müller C, Hansen A, Krause T, Park DD, Just S, Aïssi D, Börnigen D, Lindner D, Friedrich N, Alhussini K, Bening C, Schnabel RB, Karakas M, Iacoviello L, Salomaa V, Linneberg A, Tunstall-Pedoe H, Kuulasmaa K, Kirchhof P, Blankenberg S, Christ T, Eschenhagen T, Lamberts RR, Maack C, Stenzig J, Zeller T (2023)
An arrhythmogenic metabolite in atrial fibrillation.
J Transl Med. 2023 Aug 24;21(1):566
Go to Publication

Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk, M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, Eberl H, Rebs S, Streckfuss-Bömeke K, Schmitz W, Rehling P, Thum T, Higuchi T, Rabinowitz J, Maack C, Dudek J (2023)
Activation of the integrated stress response rewires the cardiac metabolism in Barth syndrome
Basic Res Cardiol 118, 47
ZGo to Publication

LeGouge K, Ashour D, Heinrichs M, Stys P, Barennes P, Stangl V, Rech L, Hoefler G, Kashofer K, Gassenmaier T, Boivin-Jahns V, Jahns R, Hofmann U, Schmitt D, Frey A, Störk S, Frantz S, Rainer P§, Ramos GC§, Mariotti-Ferrandiz (2023)
A distinct T cell receptor signature associates with cardiac outcome in myocardial infarction patients
medRxiv, 2023
Go to Publication

Lerchenmüller C, Zelarayan L, Streckfuss-Bömeke K, Gimenez MR, Schnabel R, Hashemi D, Baldus S, Rudolph TK, Morbach C (2023) 
Moving toward gender equity in the cardiology and cardiovascular research workforce in Germany: a report from the German Cardiac Society.
Eur Heart J Open. 2023 Mar 29;3(2):oead034
Go to Publication

Lichtner G, Haese T, Brose S, Röhrig L, Lysyakova L, Rudolph S, Uebe M, Sass J, Bartschke A, Hillus D, Kurth F, Sander LE, Eckart F, Toepfner N, Berner R, Frey A, Dörr M, Vehreschild JJ, von Kalle C, Thun S (2023)
Interoperable, Domain-Specific Extensions for the German Corona Consensus (GECCO) COVID-19 Research Data Set Using an Interdisciplinary, Consensus-Based Workflow: Data Set Development Study.
JMIR Med Inform, 11, e45496
Go to Publication

Liu Z, Hollmann C, Kalanidhi S, Grothey A, Keating S, Mena-Palomo I, Lamer S, Schlosser A, Kaiping A, Scheller C, Sotzny F, Horn A, Nürnberger C, Cejka V, Afshar B, Bahmer T, Schreiber S, Vehreschild JJ, Miljukov O, Schäfer C, Kretzler L, Keil T, Reese JP, Eichner FA, Schmidbauer L, Heuschmann PU, Störk S, Morbach C, Riemekasten G, Beyersdorf N, Scheibenbogen C, Naviaux RK, Williams M, Ariza ME, Prusty BK (2023)
Increased circulating fibronectin, depletion of natural IgM and heightened EBV, HSV-1 reactivation in ME/CFS and long COVID
medRxiv. 2023 Jun 29;2023.06.23.23291827
Go to Publication

Li Y, Díaz I, Martín-Valls G, Beyersdorf N, Mateu E (2023)
Systemic CD4 cytotoxic T cells improve protection against PRRSV-1 transplacental infection.
Front Immunol. 2023 Jan 17;13:1020227
Go to Publication

Morbach C, Beyersdorf N, Moser N, Pelin D, Afshar B, Ramos G, Kerkau T, Kaiser E, Lamers J, Pätkau J, Sahiti F, Albert J, Güder G, Ertl G, Angermann CE, Frantz S, Hofmann U, Jahns R, Jahns V, Störk S (2023)
Prevalence of anti-beta-1 antibody 6 months after hospitalization for acute heart failure predicts adverse outcome
ESC Heart Fail. 2023 Sep 8
Go to Publication

Morbach C, Gelbrich G, Schreckenberg M, Hedemann M, Pelin D, Scholz N, Miljukov O, Wagner A, Theisen F, Hitschrich N, Wiebel H, Stapf D, Karch O, Frantz S, Heuschmann PU, Störk S (2023)
Population data-based federated machine learning improves automated echocardiographic quantification of cardiac structure and function: the Automatisierte Vermessung der Echokardiographie project
Eur Heart J Digit Health. 2023 Nov 15;5(1):77-88
Go to Publication

Ramos GC, Frantz S, Hofmann U (2023)
Myosin-specific T-cells in myocardial diseases revisited
Circulation, 2023 cvad068
Go to Publication

Reusch J, Wagenhäuser I, Gabel A, Eggestein A, Höhn A, Lâm TT, Frey A, Schubert-Unkmeir A, Dölken L, Frantz S, Kurzai O, Vogel U, Krone M, Petri N (2023)
Influencing factors of anti-SARS-CoV-2-spike-IgG antibody titers in healthcare workers: A cross-section study. 
Journal of Medical Virology, 95(1), e28300
Go to Publication

Rizzo G, Gropper J, Piollet M, Vafadarnejad E, Rizakou A, Bandi SR, Arampatzi P, Krammer T, DiFabion N, Dietrich O, Arias-Loza AP, Prinz M, Mack M, Schlepckow K, Haass C, Silvestre JS, Zernecke A, Saliba AE, Cochain C (2023)
Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction.
Cardiovasc Res. 2023 May 2;119(3):772-785.
Go to Publication

Rosales-Alvarez RE, Rettkowski J, Herman JS, Dumbovic G, Cabezas-Wallscheid N, Grün D. (2023) 
VarID2 quantifies gene expression noise dynamics and unveils functional heterogeneity of ageing hematopoietic stem cells.
Science, 2023 Jul 13, Vol 381, Issue 6654, Pages 231-239
Go to Publication

Sangaralingham SJ, Kuhn M, Cannone V, Chen HH, Burnett JC. (2023)
Natriuretic peptide pathways in heart failure: further therapeutic possibilities.
Cardiovascular Research, Volume 118, Issue 18, Pages 3416–3433
Go to Publication

Sattler S, Campos Ramos G, Ludewig B, Rainer PP (2023)
Cardioimmunology: the new frontier!
Eur Heart J. 2023 May 11:ehad230
Go to Publication

Schreiber LM, Lohr D, Baltes S, Vogel U, Elabyad IA, Bille M, Reiter T, Kosmala A, Gassenmaier T, Stefanescu MR, Kollmann A, Aures J, Schnitter F, Pali M, Ueda Y, Williams T, Christa M, Hofmann U, Bauer W, Gerull B, Zernecke A, Ergün S, Terekhov M (2023)
Ultra-high field cardiac MRI in large animals and humans for translational cardiovascular research.
Front Cardiovasc Med. 2023 May 1
Go to Publication

Schütte JP, Manke MC, Hemmen K, Münzer P, Schörg BF, Ramos GC, Pogoda M, Dicenta V, Hoffmann SHL, Pinnecker J, Kollotzek F, Zdanyte M, Mueller KAL, Singh Y, Mack AF, Pichler B, Lang F, Nieswandt B, Gawaz M, Heinze KG, Casadei N, Borst O (2023)
Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia.
Circ Res. 2023 Mar 31
Go to Publication

Seeling M, Pöhnl M, Kara S, Horstmann N, Riemer C, Wöhner M, Liang C, Brückner C, Eiring P, Werner A, Biburger M, Altmann L, Schneider M, Amon L, Lehmann CHK, Lee S, Kunz M, Dudziak D, Schett G, Bäuerle T, Lux A, Tuckermann J, Vögtle T, Nieswandt B, Sauer M, Böckmann RA, Nimmerjahn F (2023)
Immunoglobulin G-dependent inhibition of inflammatory bone remodeling requires pattern recognition receptor Dectin-1
Immunity. 2023 May 9;56(5):1046-1063.e7
Go to Publication

Serfling SE, Hartrampf PE, Zhi Y, Higuchi T, Kosmala A, Serfling J, Schirbel A, Hörning A, Buck AK, Weich A, Werner RA (2023)
Somatostatin Receptor-Directed PET/CT for Therapeutic Decision-Making and Disease Control in Patients Affected With Small Cell Lung Cancer.
Clin Nucl Med. 2023 Apr 1;48(4):309-314
Go to Publication

Sequeira V, Batzner A, Maack C (2023)
Targeting mitochondria in hypertrophic cardiomyopathy
Eur Heart J. 2023 Apr 1;44(13):1186-1188
Go to Publication

Shoykhet M, Dervishi O, Menauer P, Hiermaier M, Moztarzadeh S, Osterloh C, Ludwig RJ, Williams T, Gerull B, Kääb S, Clauss S, Schüttler D, Waschke J, Yeruva S (2023)
EGFR inhibition leads to enhanced desmosome assembly and cardiomyocyte cohesion via ROCK activation
JCI Insight. 2023 Mar 22;8(6):e163763
Go to Publication

Stickdorn J, Czysch C, Medina-Montano C, Stein L, Xu L, Scherger M, Schild H, Grabbe S, Nuhn L. (2023) 
Peptide-Decorated Degradable Polycarbonate Nanogels for Eliciting Antigen-Specific Immune Responses.
Int J Mol Sci, 2023 Oct 21;24(20):15417
Go to Publication

Terekhov M, Elabyad IA, Lohr D, Hofmann U, Schreiber LM (2023)
High-resolution imaging of the excised porcine heart at a whole-body 7 T MRI system using an 8Tx/16Rx pTx coil.
MAGMA. 2023 Apr;36(2):279-293.
Go to Publication

Traub J, Frey A, Störk S (2023)
Chronic Neuroinflammation and Cognitive Decline in Patients with Cardiac Disease: Evidence, Relevance, and Therapeutic Implications. (2023)
Life (Basel). 2023 Jan 24;13(2):329
Go to Publication

Traub J, Schließer M, Morbach C, Frantz S, Pham M, Störk S, Stoll G, Frey A, Neugebauer H (2023)
Internal carotid artery blood flow and pulsatility index in cognitively impaired people with chronic heart failure
ESC Heart Fail. 2023 Jul 4
Go to Publication

Traub J, Schürmann P, Schmitt D, Gassenmaier T, Fette G, Frantz S, Störk S, Beyersdorf N, Boivin-Jahns V, Jahns R, Hofmann U, Frey A (2023)
Features of metabolic syndrome and inflammation independently affect left ventricular function early after first myocardial infarction.
International Journal of Cardiology 2023 Jan 1; 370: 43-50
Go to Publication

Tutov A, Chen X, Werner RA, Mühlig S, Zimmermann T, Nose N, Koshino K, Lapa C, Decker M, Higuchi T (2023)
Rationalizing the Binding Modes of PET Radiotracers Targeting the Norepinephrine Transporter.
Pharmaceutics. 2023 Feb 17;15(2):690
Go to Publication

Wagenhäuser I, Mees J, Reusch J, Lâm TT, Schubert-Unkmeir A, Krone LB, Frey A, Kurzai O, Frantz S, Dölken L, Liese J, Gabel A, Petri N, Krone M (2023)
Determinants of Influenza A infection rate in post-COVID-19 era. 
J Infect, 87(4), 361-364
Go to Publication

Wagenhäuser I, Reusch J, Gabel A, Höhn A, Lâm TT, Almanzar G, Prelog M, Krone LB, Frey A, Schubert-Unkmeir A, Dölken L, Frantz S, Kurzai O, Vogel U, Petri N, Krone, M (2023)
Immunogenicity and safety of coadministration of COVID-19 and influenza vaccination. 
Eur Respir J, 61, 2201390
Go to Publication 

Walz K, Janz A, Klopocki E, Gerull B (2023)
Generation of a CRISPR/Cas9-edited Plakoglobin (JUP) knock-out (JMUi001-A-4) iPSC line to model the cardiac phenotype of arrhythmogenic cardiomyopathy
Stem Cell Res. 2023 Dec;73:103240
Go to Publication

Weich A, Serfling SE, Rowe SP, Solnes LB, Buck AK, Higuchi T, Werner RA (2023)
Partial Response Upon Peptide Receptor Radionuclide Therapy in a Highly Proliferative Pancreatic Neuroendocrine Tumor
Clin Nucl Med. 2023 Mar 16
Go to Publication

Weich A, Serfling SE, Yi H, Buck AK, Higuchi T, Werner RA. (2023)
Complete Remission Upon Peptide Receptor Radionuclide Therapy in a G2 Pancreatic Neuroendocrine Tumor.
Clin Nucl Med. 2023 Apr 1;48(4):335-336
Go to Publication

Weissman D, Maack C (2023)
Mitochondrial function in macrophages controls cardiac repair after myocardial infarction
J Clin Invest. 2023 Feb 15;133(4):e167079
Go to Publication

Weiss LJ, Drayss M, Manukjan G, Zeitlhöfler M, Kleiss J, Weigel M, Herrmann J, Mott K, Beck S, Burkard P, Lâm TT, Althaus K, Bakchoul T, Frantz S, Meybohm P, Nieswandt B, Weismann D, Schulze H (2023)
Uncoupling of platelet granule release and integrin activation suggests GPIIb/IIIa as a therapeutic target in COVID-19
Blood Adv. 2023 Jun 13;7(11):2324-2338
Go to Publication

Weiss LJ, Drayss M, Mott K, Beck S, Unsin D, Just B, Speer CP, Hartel C, Andres O, Schulze H (2023)
Ontogenesis of functional platelet subpopulations from preterm and term neonates to adulthood: The PLINIUS study
Blood Adv 7(16): 4334-4348
Go to Publication

Werner F, Prentki Santos E, Michel K, Schrader H, Völker K, Potapenko T, Krebes L, Abesser M, Möllmann D, Schlattjan M, Schmidt H, Skryabin BV, Špiranec Spes K, Schuh K, Denton CP, Baba HA, Kuhn M (2023)
Ablation of C-type natriuretic peptide/cGMP signaling in fibroblasts exacerbates adverse cardiac remodeling in mice
JCI Insight. 2023 May 25;e160416
Go to Publication

Werner RA, Hartrampf PE, Fendler WP, Serfling SE, Derlin T, Higuchi T, Pienta KJ, Gafita A, Hope TA, Pomper MG, Eiber M, Gorin MA, Rowe SP (2023)
Prostate-specific Membrane Antigen Reporting and Data System Version 2.0
Eur Urol. 2023 Jul 4;S0302-2838(23)02903-2
Go to Publication

Werner RA, Lütje S, Habacha B, Bundschuh L, Higuchi T, Buck AK, Kosmala A, Lapa C, Essler M, Lodge MA, Pienta KJ, Eisenberger MA, Markowski MC, Gorin MA, Pomper MG, Rowe SP, Bundschuh RA (2023)
Test-retest repeatability of organ uptake on PSMA-targeted 18 F-DCFPyL PET/CT in patients with prostate cancer
Prostate. 2023 May 21
Go to Publication

Wu H, Zhao X, Hochrein SM, Eckstein M, Gubert GF, Knöpper K, Mansilla AM, Öner A, Doucet-Ladevèze R, Schmitz W, Ghesquière B, Theurich S, Dudek J, Gasteiger G, Zernecke A, Kobold S, Kastenmüller W, Vaeth M (2023)
Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming
Nat Commun.;14(1):6858
Go to Publication

Zhang Y, Vandestienne M, Lavillegrand JR, Joffre J, Santos-Zas I, Lavelle A, Zhong X, Le Goff W, Guérin M, Al-Rifai R, Laurans L, Bruneval P, Guérin C, Diedisheim M, Migaud M, Puel A, Lanternier F, Casanova JL, Cochain C, Zernecke A, Saliba AE, Mokry M, Silvestre JS, Tedgui A, Mallat Z, Taleb S, Lenoir O, Vindis C, Camus SM, Sokol H, Ait-Oufella H (2023)
Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy
Nat Commun. 2023 Aug 1;14(1):4622
Go to Publication

Zernecke A, Erhard F, Weinberger T, Schulz C, Ley K, Saliba AE, Cochain C (2023)
Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis
Cardiovasc Res. 2023 Jul 6;119(8):1676-1689
Go to Publication

 

§Corresponding authors

Publications 2022

Bertero E, Dudek J, Cochain C, Delgobo M, Ramos G, Gerull B, Higuchi T, Vaeth M, Zernecke A, Frantz S, Hofmann U, Maack C (2022)
Immuno-metabolic interfaces in cardiac disease and failure.
Cardiovasc Res 2022 Jan 7;118(1):37-52
Go to Publication

Brodehl A, Gerull B (2022)
Genetic Insights into Primary Restrictive Cardiomyopathy.
Journal of Clinical Medicine 2022 Apr 8; 11(8): 2094
Go to Publication

Brown HC, Beck S, Navarro S, Di Y, Soriano Jerez EM, Kaczmarzyk J, Thomas SG, Mirakaj V, Watson SP, Nieswandt B, Stegner D (2022)
Antibody-mediated depletion of human CLEC-2 in a novel humanised mouse model.
Blood Advances 2022 Aug: 2021006463
No abstract available
Go to Publication

Delgobo M, Weiß E, Ashour D, Popiolkowski L, Arampatzi P, Stangl V, Arias-Loza P, Rainer P, Saliba AE, Ludewig B, Hofmann U, Frantz S, Campos Ramos G (2022)
Rapid differentiation of regulatory CD4+ T cells in the infarcted myocardium blunts in situ inflammation.
bioRxiv 2022 Mar 27
Go to Publication

Dolejsi T, Delgobo M, Schuetz T, Tortola L, Heinze KG, Hofmann U, Frantz S, Bauer A, Ruschitzka F, Penninger JM, Campos Ramos G, Haubner BJ (2022)
Adult T-cells impair neonatal cardiac regeneration.
European Heart Journal 2022 Jul 21; 43(28): 2698-2709
Go to Publication 

Chen X, Werner RA, Koshino K, Nose N, Mühlig S, Rowe SP, Pomper MG, Lapa C, Decker M, Higuchi T (2022)
A Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity – Introducing High NET Affinity PET Probe 18F-AF78.
Theranostics 2022 May 24; 12(9): 4446-4458
Go to Publication

Czysch C, Medina Montano C, Zhong Z, Fuchs A, Stickdorn J, Nuhn L (2022) 
Transient lymph node immune activation by hydrolysable poly(carbonate) nanogels.
Advanced Functional Materials, Volume32, Issue35, August 25
Go to Publication

Emanuelli G, Zoccarato A, Reumiller CM, Papadopoulos A, Chong M, Rebs S, Betteridge K, Beretta M, Streckfuss-Bömeke K, Shah AM (2022)
A roadmap for the characterization of energy metabolism in human cardiomyocytes derived from induced pluripotent stem cells.
J Mol Cell Cardiol. 2022 Mar:164:136-147
Go to Publication

Erhard F, Saliba AE, Lusser A, Toussaint C, Hennig T, Prusty BK, Kirschenbaum D, Abadie K, Miaka EA, Friedel CC, Amit I, Micura R, Dölken L (2022)
Time-resolved single-cell RNA-seq using metabolic RNA labelling.
Nature Revies Methods Primers 2022 Sep 29: 2(77)
Go to Publication

Frantz S, Hundertmark MJ, Schulz-Menger J, Bengel FM, Bauersachs J (2022)
Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies.
European Heart Journal 2022 Jul 14; 43(27): 2549-2561
Go to Publication

Frey A, Leutritz T, Backhaus J, Hörnlein A, König S. (2022)
Item format statistics and readability of extended matching questions as an effective tool to assess medical students.
Scientific Reports, 12(1):20982
Go to Publication

Hapke N, Heinrichs M, Ashour D, Vogel E, Hofmann U, Frantz S, Campos Ramos G (2022)
Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarction.
Journal of Molecular and Cellular Cardiology (JMCC) 2022 Dec; 173: 25-29
Go to Publication

Higuchi T, Serfling SE, Rowe SP, Werner RA (2022)
Therapeutic Effects of Lipid Lowering Medications on Myocardial Blood Flow, Inflammation, and Sympathetic Nerve Activity Using Nuclear Techniques.
Current Cardiology Reports 2022 Dec; 24(12): 1849-1853
Go to Publication

Higuchi T, Werner RA (2022)
Unfolding the cardioprotective potential of sigma-1 receptor-directed molecular imaging.
Editorial Journal of Nuclear Cardiology 2022 Aug 4
No abstract available
Go to Publication

Hochrein SM, Wu H, Eckstein M, Arrigoni L, Herman JS, Schumacher F, Gerecke C, Rosenfeldt M, Grün D, Kleuser B, Gasteiger G, Kastenmüller W, Ghesquière B, Van den Bossche J, Abel ED, Vaeth M (2022)
The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming.
Cell Metabolism 2022 Apr 5; 34(4): 516-532.e11
Go to Publication

Jeson Sangaralingham S, Kuhn M, Cannone V, Chen HH, Burnett JC (2022)
Natriuretic peptide pathways in heart failure - further therapeutic possibilities.
Cardiovascular Research 2022 Aug 25: 118(18): 3416-3433
Go to Publication

Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, Künzel SR, Kämmerer S, Günscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L , Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M, El-Armouche A (2022)
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
Nature Communications 2022 Dec 10; 13(1): 7648
Go to Publication

Klingenberg R, Holtkamp F, Grün D, Frey A, Jahns V, Jahns R, Gassenmaier T, Hamm CW, Frantz S, Keller T (2022)
Use of serial changes in biomarkers vs. baseline levels to predict left ventricular remodelling after STEMI.
ESC Heart Fail. 2022 Oct 21.
Go to Publication

Lambertini A, Hartrampf PE, Higuchi T, Serfling SE, Meybohm P, Schirbel A, Buck AK, Werner RA (2022)
CXCR4-targeted molecular imaging after severe SARS-Cov-2 infection.
European Journal of Nuclear Medicine and Molecular Imaging 2022 Dec; 50(1): 228-229
Go to Publication

Lee J, Olivieri C, Ong C, Masterson LR, Gomes S, Lee BS, Schaefer F, Lorenz K, Veglia G, Rosner MR (2022)
Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop.
Proc Natl Acad Sci U S A. 2022:119(25):e2121867119
Go to Publication

Lopez Krol A, Nehring HP, Krause FF, Wempe A, Raifer H, Nist A, Stiewe T, Bertrams W, Schmeck B, Luu M, Leister H, Chung H-R, Bauer U-M, Adhikary T, Visekruna A (2022)
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells. EMBO Rep:e54685.
Go to Publication

Matsusaka Y, Werner RA, Arias-Loza P, Nose N, Sasaki T, Chen X, Lapa C, Higuchi T (2022)
Performance Evaluation of a Preclinical SPECT Scanner with a Collimator Designed for Medium-Sized Animals.
Molecular Imaging 2022 Jul 16; 2022: 9810097Z
Go to Publication

Merches K, Breunig L, Fender J, Brand T, Bätz V, Idel S, Kollipara L, Reinders Y, Sickmann A, Mally A, Lorenz K (2022)
The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro.
Archives of Toxicology 2022 Aug; 96(8): 2341-2360
Go to Publication

Petzold T, Zhang Z, Ballesteros I, Saleh I, Polzin A, Thienel M, Liu L, Ul Ain Q, Ehreiser V, Weber C, Kilani B, Mertsch P, Götschke J, Cremer S, Fu W, Lorenz M, Ishikawa-Ankerhold H, Raatz E, El-Nemr S, Görlach A, Marhuenda E, Stark K, Pircher J, Stegner D, Gieger C, Schmidt-Supprian M, Gaertner F, Almendros I, Kelm M, Schulz C, Hidalgo A, Massberg S (2022)
Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.
Immunity 2022 Dec 13; 55(12): 2285-2299
Go to Publication

Ramos CG, Hudecek M (2022)
The era of in vivo T cell engineering.
Med (N Y) 2022 Feb 11; 3(2): 85-86
Go to Publication

Rizzo G, Gropper J, Piollet M, Vafadarnejad E, Rizakou A, Bandi SR, Arampatzi P, Krammer T, DiFabion N, Dietrich O, Arias-Loza AP, Prinz M, Mack M, Schlepckow K, Haass C, Silvestre JS, Zernecke A, Saliba AE, Cochain C (2022)
Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction.
Cardiovascular Research 2022 Aug 11; cvac113
Go to Publication

Rohde D§, Vandoorne K§, Lee IH, Grune J, Zhang S, McAlpine CS, Schloss MJ, Nayar R, Courties G, Frodermann V, Wojtkiewicz G, Honold L, Chen Q, Schmidt S, Iwamoto Y, Sun Y, Cremer S, Hoyer FF, Iborra-Egea O, Munoz-Guijosa C, Ji F, Zhou B, Adams RH, Wythe JD, Hidalgo J, Watanabe H, Jung Y, van der Laan AM, Piek JJ, Kfoury Y, Desogere PA, Vinegoni C, Dutta P, Sadreyev RI, Caravan P, Bayes-Genis A, Libby P, Scadden DT, Lin CP, Naxerova K, Swirski FK, Nahrendorf M (2022) 
Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease. 
Nature Cardiovascular Research volume 1, pages 28–44
Go to Publication

Schanbacher C, Bieber M, Reinders Y, Cherpokova D, Teichert C, Nieswandt B, Sickmann A, Kleinschnitz C, Langhauser F, Lorenz K (2022)
ERK1/2 Activity Is Critical for the Outcome of Ischemic Stroke. 
Int J Mol Sci. 2022 Jan 9;23(2):706
Go to Publication

Schinner C, Xu L, Franz H, Zimmermann A, Wanuske MT, Rathod M, Hanns P, Geier F, Pelczar P, Liang Y, Lorenz V, Stüdle C, Maly PI, Kauferstein S, Beckmann BM, Sheikh F, Kuster GM, Spindler V (2022)
Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade. Circulation 146:1610-1626
Go to Publication

Shaikh H, Pezoldt J, Mokhtari Z, Gamboa Vargas J, Le D-D, Peña Mosca J, Arellano Viera E, Kern MA, Graf C, Beyersdorf N, Lutz MB, Riedel A, Büttner-Herold M, Zernecke A, Einsele H, Saliba A-E, Ludewig B, Huehn J, Beilhack A (2022)
Fibroblastic reticular cells mitigate acute GvHD via MHCII-dependent maintenance of regulatory T cells. 
JCI Insight 7
Go to Publication

Stickdorn J, Stein L, Arnold-Schild D, Hahlbrock J, Medina-Montano C, Bartneck J, Ziss T, Montermann E, Kappel C, Hobernik D, Haist M, Yurugi H, Raabe M, Best A, Rajalingam K, Radsak MP, David SA, Koynov K, Bros M, Grabbe S, Schild H, Nuhn L (2022) 
Systemically Administered TLR7/8 Agonist and Antigen-Conjugated Nanogels Govern Immune Responses against Tumors.
ACS Nano. 2022 Mar 22;16(3):4426-4443
Go to Publication

Tolstik E, Ali N, Guo S, Ebersbach P, Möllmann D, Arias-Loza P, Dierks J, Schuler I, Freier E, Debus J, Baba HA, Nordbeck P, Bocklitz T, Lorenz K (2022)
CARS Imaging Advances Early Diagnosis of Cardiac Manifestation of Fabry Disease.
International Journal of Molecular Sciences 2022 May 11; 23(10): 5345
Go to Publication

Tolstik E, Gongalsky MB, Dierks J, Brand T, Pernecker M, Pervushin NV, Maksutova DE, Gonchar KA, Samsonova JV, Kopeina G, Sivakov V, Osminkina LA, Lorenz K (2022)
Raman and fluorescence micro-spectroscopy applied for the monitoring of sunitinib-loaded porous silicon nanocontainers in cardiac cells. NEKAR study group.
Frontiers of Pharmacology 2022 Aug 9; 13: 962763
Go to Publication

Traub J, Grondey K, Gassenmaier T, Schmitt D, Fette G, Frantz S, Boivin-Jahns V, Jahns R, Störk S, Stoll G, Reiter T, Hofmann U, Weber MS, Frey A (2022)
Sustained Increase in Serum Glial Fibrillary Acidic Protein after First ST-Elevation Myocardial Infarction.
International Journal of Molecular Sciences 2022 Sep 7; 23(18): 10304
Go to Publication

Traub J, Otto M, Sell R, Homola GA, Steinacker P, Oeckl P, Morbach C, Frantz S, Pham M, Störk S, Stoll G, Frey, A (2022)
Serum glial fibrillary acidic protein indicates memory impairment in patients with chronic heart failure.
ESC Heart Failure, 9(4), 2626–2634
Go to Publication

Traub J, Otto M, Sell R, Göpfert D, Homola G, Steinacker P, Oeckl P, Morbach C, Frantz S, Pham M, Störk S, Stoll G, Frey A (2022)
Serum phosphorylated tau protein 181 and neurofilament light chain in cognitively impaired heart failure patients.
Alzheimers´ Resarch and Therapy 2022 Oct 10; 14(1): 149
Go to Publication

Weiß E, Ramos GC, Delgobo M. (2022)
Myocardial-Treg Crosstalk: How to Tame a Wolf.
Frontiers in Immunology 2022 May 25; 13: 914033
Go to Publication

Weiss LJ, Drayss M, Manukjan G, Zeitlhoefler M, Kleiss J, Weigel ML, Herrmann J, Mott K, Beck S, Burkard P, Lam TT, Althaus K, Bakchoul T, Frantz S, Meybohm P, Nieswandt B, Weismann D, Schulze H
Uncoupling of platelet granule release and integrin activation suggests GPIIb/IIIa as therapeutic target in COVID-19
Blood Adv. 13;7(11):2324-2338
Go to Publication

Weiss LJ, Drayss M, Mott K, Droste M, Just B, Arold AM, Nieswandt B, Weismann D, Stegner D, Schulze H (2022)
The homophilic CD84 receptor is upregulated on platelets in COVID-19 and sepsis.
Thrombosis Research 2022 Dec; 220: 121-124
Go to Publication

Werner RA, Higuchi T, Nose N, Toriumi F, Matsusaka Y, Kuji I, Kazuhiro K (2022)
Generative adversarial network-created brain SPECTs of cerebral ischemia are indistinguishable to scans from real patients.
Scientific Reports 2022 Nov 5; 12(1): 18787
Go to Publication

Werner RA, Martinez RB, Marcus C, Kruse MJ, Sheikhbahaei S, Solnes LB, Higuchi T, Javadi MS, Rowe SP (2022)
Diagnostic performance of IQ·SPECT with high-speed scanning: A preliminary quality control study in obese patients.
Journal of Nuclear Cardiology. 2022 Dec; 29(6): 3443-3449
Go to Publication

Zernecke A, Erhard F, Weinberger T, Schulz C, Ley K, Saliba AE, Cochain C (2022)
Integrated single-cell analysis based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis.
Cardiovascular Research 2022 Oct 3; cvac161
Go to Publication

Anschrift

Medizinische Klinik und Poliklinik I, Universitätsklinikum Würzburg, Zentrum für Innere Medizin (ZIM), Oberdürrbacher Straße 6, Haus A3, 97080 Würzburg, Deutschland 

Deutsches Zentrum für Herzinsuffizienz Würzburg | Comprehensive Heart Failure Center | Am Schwarzenberg 15 | Haus A15 | 97078 Würzburg