Publications of CRC 1525

Williams T, Groß R, Arias-Loza AP, Nordbeck P, Noerpel M, Cirnu A, Kimmel L, DiyaaEldin D, Ramos G, Waschke J, Higuchi T, Gerull B
Insights from [18F]-FDG PET Imaging in Jup-Associated Arrhythmogenic Cardiomyopathy
J Am Heart Assoc. 2025;13:e038331
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Rizakou A†, Bauer M†, Delgobo M, Hofmann A, Heinrichs M, Reiter T, Werner R, Saliba AE, Jahns R, Jahns V, Nikolaev VO, Mariotti-Ferrandiz  E, Ashour D, Frantz S§ and Campos Ramos G
Characterization of ADRB1-specific TCR motifs in patients with myocardial infarction
In submission (*). † Shared authorship. § Shared senior authorship
Zur Publikation

Brand T, Baumgarten BT, Denzinger S, Reinders Y, Kleindl M, Schanbacher C, Funk F, Gedik N, Jabbasseh M, Kleinbongard P, Dudek J, Szendroedi J, Tolstik E, Schuh K, Krüger M, Dobrev D, Cuello F, Sickmann A, Schmitt JP, Lorenz K
From Ca2+dysregulation to heart failure: β-adrenoceptor activation by RKIP postpones molecular damages and subsequent cardiac dysfunction in mice carrying mutant PLNR9C by correction of aberrant Ca2+-handling
Pharmacol Res. 2025 Jan;211:107558
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Siegel J, Beer D, Janjatovic S, Ashour D, Auer A, Zipp L, Kozuch E, Dudek J, Krammer T, Saliba AE, Cochain C, Störk S, Heuschmann P, Morbach C, Hofmann U, Frantz S, Wardemann H, Heinrichs M, Heinze KG, Streckfuss-Bömeke K, Ramos GC
Heart- reactive antibodies impair cardiomyocyte function and fuel post-myocardial infarction inflammation
in submission

Kusch C*, Stegner D*, Johnson D, Nurden P, Burkard P, Bergmeier W, Onursal C, Navarro S, Hackenbroch C, Meub M, Gross Ca, Weiss LJ, Schenk J, Bender M, Andres O, Kastenmüller W, Heinze KG, Sauer M, Schulze H, Ley K, Nurden AT, Nieswandt B
Platelet-derived Integrin and Tetraspanin-enriched Tethers Exacerbate Severe Inflammation
in revision

Rizakou A, Rosa A, Sakalli E, Rizzo G, Burkard P, Arampatzi P, Beck S, Gundel S, Klapproth K, Bandi SR, Piollet M, Göb V, Stegner D, Zernecke A, Nieswandt B*, Cochain C
Platelets drive macrophage inflammatory activation in vitro
in revision

Shing Fung Chan A, Greiner J, Brennan T, Agrawal A, Hemmer H, Sinning K, Marschhäuser L, Cheung WL, Iqbal Z, Klesen A, Seidel T, Vaeth M, Rog-Zielinska E, Kohl P, Schneider-Warme F and Grün D
Spatio-temporal dynamics of the fibrotic niche in cardiac repair
BioRxiv 2024
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Rizakou A, Weiss LJ, Sakalli ET, Giuseppe Rizzo, Beck S, Burkard P, Rosa A, Bandi SR, Piollet M, Göb V, Krammer T, Saliba AE, Stegner D, Zernecke A, Cochain C, Nieswandt B
Targeting the platelet GPIIbIIIa-GPVI axis minimally affect acute inflammation and cardiac repair in experimental permanent myocardial infarction

A. Sink, H. Gerwe, H. Hübner, V. Boivin-Jahns, J. Fender, K. Lorenz, P. Gmeiner, M. Decker*
Photo-Adrenalines: b2-Adrenergic receptor agonists as molecular probes for the study of spatiotemporal adrenergic signaling”
Chem. Eur. J. 2024, in press
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Bielenberg M, Kurelic R, Frantz S, Nikolaev VO
A mini-review: phosphodiesterases in charge to balance intracellular cAMP during T-cell activation
Front Immunol. 2024 Mar 8:15:1365484
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Ascheid D, Baumann M, Pinnecker J, Friedrich M, Szi-Marton D, Medved C, Bundalo M, Ortmann V, Öztürk A, Nandigama R, Hemmen K, Ergün S, Zernecke A, Hirth M, Heinze KG§, Henke E§
A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy
Nat Commun. 2024 Apr 27;15(1):3599
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Lavillegrand JR, Al-Rifai R, Thietart S, Guyon T, Vandestienne M, Cohen R, Duval V, Zhong X, Yen D, Ozturk M, Negishi Y, Konkel J, Pinteaux E, Lenoir O, Vilar J, Laurans L, Esposito B, Bredon M, Sokol H, Diedisheim M, Saliba AE, Zernecke A, Cochain C, Haub J, Tedgui A, Speck NA, Taleb S, Mhlanga MM, Schlitzer A, Riksen NP, Ait-Oufella H
Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming
Nature. 2024 Oct;634(8033):447-456
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Kollmann A, Lohr D, Ankenbrand MJ, Bille M, Terekhov M, Hock M, Elabyad I, Baltes S, Reiter T, Schnitter F, Bauer WR, Hofmann U, Schreiber LM
Cardiac function in a large animal model of myocardial infarction at 7 T: deep learning based automatic segmentation increases reproducibility
2024 May 14;14(1):11009
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Tolstik E, Lehnart SE, Soeller C, Lorenz K, Sacconi L.
Cardiac multiscale bioimaging: from nano- through micro- to mesoscales
Trends Biotechnol. 2024 Feb;42(2):212-227
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Kerp H, Gassen J, Grund SC, Hönes GS, Dörr S, Mittag J, Härting N, Kaiser F, Moeller LC, Lorenz K§, Führer D§
Cardiac recovery from pressure overload is not altered by thyroid hormone status in old mice. Front Endocrinol (Lausanne)
2024 Feb 22;15:1339741
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Schäfer S, Gogiraju R, Rösch M, Kerstan Y, Beck L, Garbisch J, Saliba AE, Gisterå A, Hermanns HM, Boon L, Kastenmüller W, Schäfer K, Cochain C, Zernecke A
CD8+ T Cells Drive Plaque Smooth Muscle Cell Dedifferentiation in Experimental Atherosclerosis
Arterioscler Thromb Vasc Biol. 2024 44(8):1852-1872
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Schnitter F, Stangl F, Noeske E, Bille M, Stadtmüller A, Vogt N, Sicklinger F, Leuschner F, Frey A, Schreiber L, Frantz S, Beyersdorf N, Ramos G, Gladow N and Hofmann U
Characterizing the immune response to myocardial infarction in pigs
Basic Res Cardiol. 2024; 119(3):453-479
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Cachorro E, Günscht M, Schubert M, Sadek MS, Siegert J, Dutt F, Bauermeister C, Quickert S, Berning H, Nowakowski F, Lämmle S, Firneburg R, Luo X, Künzel SR, Klapproth E, Mirtschink P, Mayr M, Dewenter M, Vettel C, Heijman J, Lorenz K, Guan K, El-Armouche A, Wagner M, Kämmerer S.
CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2
Circ Res. 2023 Feb 17;132(4):400-414
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Dreher N*, Dörrler A-L*, Kraus S, Higuchi T, Serfling SE, Samnick S, Einsele H, Grigoleit GU, Buck AK, Werner RA
C-X-C Motif Chemokine Receptor 4-Targeted Radioligand Therapy in Hematological Malignancies – Myeloablative Effects, Anti-Lymphoma Activity and Safety Profile
Clin Nucl Med. 2024 Feb 1;49(2):146-151
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Spatz P, Chen X, Reichau K, Huber ME, Mühlig S, Matsusaka Y, Schiedel M, Higuchi T, Decker M
Development and Initial Characterization of the First 18F-CXCR2-Targeting Radiotracer for PET Imaging of Neutrophils
J Med Chem 2024 Apr 25;67(8):6327-6343
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D. A. Rodríguez-Soacha, S. A. M. Steinmüller, A. Isbilir, J. Fender, M. H. Deventer, Y. Ramirez, A. Tutov, C. Sotriffer, Christophe P. Stove, K. Lorenz, M. Lohse; J. Hislop, M. Decker*
Development of an indole-amide-based photopharmacological tool compound acting as a selective cannabinoid receptor subtype 1 “cis-on” agonist
ACS Chem. Neurosci. 2022, 13(16), 2410-2435
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Ashour D, Le Gouge K, Rainer PP, Mariotti-Ferrandiz E, Ramos GC
Exploring T Cell Receptor Repertoires in Myocardial Diseases
Circ Res. 2024 Jun 7;134(12):1808-1823
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Traub J, Schürmann P, Schmitt D, Gassenmaier T, Fette G, Frantz S, Störk S, Beyersdorf N, Boivin-Jahns V, Jahns R, Hofmann U, Frey A
Features of metabolic syndrome and inflammation independently affect left ventricular function early after first myocardial infarction
Int J Cardiol. 2023;370:43-50
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Zhang Y, Vandestienne M, Lavillegrand JR, Joffre J, Santos-Zas I, Lavelle A, Zhong X, Le Goff W, Guérin M, Al-Rifai R, Laurans L, Bruneval P, Guérin C, Diedisheim M, Migaud M, Puel A, Lanternier F, Casanova JL, Cochain C, Zernecke A, Saliba AE, Mokry M, Silvestre JS, Tedgui A, Mallat Z, Taleb S, Lenoir O, Vindis C, Camus SM, Sokol H, Ait-Oufella H
Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy
Nat Commun. 2023 Aug 1;14(1):4622
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Richter L, Bauer M, Bernsen C, Vogel E, Mahmud Z, Saliba AE, Schulz R, Frantz S, Ashour D†, Ramos GC
Identification of a novel myosin antigen activating CD8+ T cells in C57BL/6 mice
bioRxiv; 2024. †Shared senior authorship.
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Kammerer J, Cirnu A, Williams T, Hasselmeier M, Nörpel M, Chen R, Gerull B
Macro-based collagen quantification and segmentation in picrosirius red-stained heart sections using light microscopy
Biol Methods Protoc. 2024 Apr 27;9(1):bpae027
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Staudt S, Nikolka F, Perl M, Franz J, Leblay N, Yuan X, Warmuth L, Fante MA, Skorpskaite A, Fei T, Bromberg Maria, San Martin-Uriz P, Rodriguez-Madoz JR, Ziegler-Martin K, Adil Gholam N, Benz P, Tran Huu P, Stein-Thoeringer C, Schmitt M, Kleigrewe K, Freitag F, Riester R, Weber J, Mangold K, Einsele H, Prosper P, Ellmeier W, Busch D, Visekruna V, Slingerland J, Shouval R, Hiller H, van den Brink M, Pausch P, Neri P, Hudecek M, Poeck H, Luu M+
Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells
bioRxiv
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X. Chen, R. A. Werner, K. Koshino, N. Nose, S. Mühlig, S. P. Rowe, M. G. Pomper, C. Lapa, M. Decker*, T. Higuchi*
Molecular imaging-derived biomarker of cardiac nerve integrity - Introducing high NET affinity PET probe 18F-AF78
Theranostics 2022, 12(9), 4446-4458
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Janz A, Walz K, Cirnu A, Surjanto J, Urlaub D, Leskien M, Kohlhaas M, Nickel A, Brand T, Nose N, Wörsdörfer P, Wagner N, Higuchi T, Maack C, Dudek J, Lorenz K, Klopocki E, Ergün S, Duff HJ, Gerull B.
Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes
Mol Metab. 2024 Jan;79:101859
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Reyat JS, Sommerfeld LC, O'Reilly M, Roth Cardoso V, Thiemann E, Khan AO, O'Shea C, Harder S, Müller C, Barlow J, Stapley RJ, Chua W, Kabir SN, Grech O, Hummel O, Hübner N, Kääb S, Mont L, Hatem SN, Winters J, Zeemering S, Morgan NV, Rayes J, Gehmlich K, Stoll M, Brand T, Schweizer M, Piasecki A, Schotten U, Gkoutos GV, Lorenz K, Cuello F, Kirchhof P, Fabritz L
PITX2 deficiency leads to atrial mitochondrial dysfunction
Cardiovasc Res. 2024 Dec 4;120(15):1907-1923
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Lohr D, Kollmann A, Bille M, Terekhov M, Elabyad I, Hock M, Baltes S, Reiter T, Schnitter F, Bauer WR, Hofmann U, Schreiber LM
Precision imaging of cardiac function and scar size in acute and chronic porcine myocardial infarction using ultrahigh-field MRI
Commun Med (Lond). 2024 Jul 18;4(1):146.*
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A. Tutov, X. Chen, S. Mühlig, R. A. Werner, S. Mühlig. T. Zimmermann, N. Nose, K. Koshino, C. Lapa, M. Decker*, T. Higuchi*
Rationalizing binding modes of radiotracers targeting norepinephrine transporter after initial translational studies
Pharmaceutics 2023, 15(2), 690
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Bundalo M, Vorlova S, Ulrich J, Barbieri R, Richter L, Höna L, Egg M, Bock J, Schäfer S, Amézaga Solé N, Rosa A, Rizzo G, Cochain C, Kastenmüller W, Henke E, Skryabin BV, Rozhdestvensky TS, Wildgruber M, Lorenz M, Kuhn M, Zernecke A
Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis
bioRxiv
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Hilgendorf I, Frantz S, Frangogiannis NG
Repair of the Infarcted Heart: Cellular Effectors, Molecular Mechanisms and Therapeutic Opportunities
Circ Res. 2024 Jun 7;134(12):1718-1751
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Li Y, Díaz I, Martín-Valls G, Beyersdorf N and Mateu E
Systemic CD4 cytotoxic T cells improve protection against PRRSV-1 transplacental infection
Front Immunol. 2023; 13:1020227
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Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, Künzel SR, Kämmerer S, Günscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L, Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M, El-Armouche A
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction
Nat Commun. 2022 Dec 10;13(1):7648
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Asquith NL, Carminita E, Camacho V, Rodriguez-Romera A, Stegner D, Freire D, Becker IC, Machlus KR, Khan A, Italiano JE Jr
The bone marrow is the primary site of thrombopoiesis
Blood 2024; 143(3): 272-278
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Navarro S, Talucci I, Göb V, Hartmann S, Beck S, Orth V, Stoll G, Maric HM, Stegner D, Nieswandt B 
The humanized platelet glycoprotein VI Fab inhibitor EMA601 protects from arterial thrombosis and ischaemic stroke in mice
Eur Heart J. 45(43):4582-4597
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Cachorro E, Günscht M, Schubert M, Sadek MS, Siegert J, Dutt F, Bauermeister C, Quickert S, Berning H, Nowakowski F, Lämmle S, Firneburg R, Luo X, Künzel SR, Klapproth E, Mirtschink P, Mayr M, Dewenter M, Vettel C, Heijman J, Lorenz K, Guan K, El-Armouche
TREM2 protects from atherosclerosis by limiting necrotic core formation
Nat Cardiovasc Res. 2024 Mar;3(3):269-282
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S. A. M. Steinmüller, J. Fender, M. H. Deventer, A. Tutov, K. Lorenz, C. P. Stove, J. N. Hislop, M. Decker*
Visible light photoswitchable benzimidazole azo-arenes as β-arrestin2-biased selective cannabinoid 2 receptor agonists
Angew. Chem. Int. Ed. 2023, 62(49), e202306176 – selected for frontispiece picture
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LeGouge K, Ashour D, Heinrichs M, Stys P, Barennes P, Stangl V, Rech L, Hoefler G, Kashofer K, Gassenmaier T, Boivin-Jahns V, Jahns R, Hofmann U, Schmitt D, Frey A, Störk S, Frantz S, Rainer P§, Ramos GC§, Mariotti-Ferrandiz
A distinct T cell receptor signature associates with cardiac outcome in myocardial infarction patients
medRxiv, 2023 §Corresponding authors
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Werner F, Prentki Santos E, Michel K, Schrader H, Völker K, Potapenko T, Krebes L, Abesser M, Möllmann D, Schlattjan M, Schmidt H, Skryabin BV, Špiranec Spes K, Schuh K, Denton CP, Baba HA, Kuhn M
Ablation of C-type natriuretic peptide/cGMP signaling in fibroblasts exacerbates adverse cardiac remodeling in mice
JCI Insight. 2023 May 25;e160416
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Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk, M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, Eberl H, Rebs S, Streckfuss-Bömeke K, Schmitz W, Rehling P, Thum T, Higuchi T, Rabinowitz J, Maack C, Dudek J
Activation of the integrated stress response rewires the cardiac metabolism in Barth syndrome
Basic Res Cardiol 118, 47
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Dolejsi T, Delgobo M, Schuetz T, Tortola L, Heinze KG, Hofmann U, Frantz S, Bauer A, Ruschitzka F, Penninger JM, Campos Ramos G, Haubner BJ
Adult T-cells impair neonatal cardiac regeneration
Eur Heart J. 2022 Jul 21;43(28):2698-2709
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Krause J, Nickel A, Madsen A, Aitken-Buck HM, Stoter AMS, Schrapers J, Ojeda F, Geiger K, Kern M, Kohlhaas M, Bertero E, Hofmockel P, Hübner F, Assum I, Heinig M, Müller C, Hansen A, Krause T, Park DD, Just S, Aïssi D, Börnigen D, Lindner D, Friedrich N, Alhussini K, Bening C, Schnabel RB, Karakas M, Iacoviello L, Salomaa V, Linneberg A, Tunstall-Pedoe H, Kuulasmaa K, Kirchhof P, Blankenberg S, Christ T, Eschenhagen T, Lamberts RR, Maack C, Stenzig J, Zeller T
An arrhythmogenic metabolite in atrial fibrillation
J Transl Med. 2023 Aug 24;21(1):566.
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Ashour DE, Rebs S, Arampatzi P, Saliba AE, Dudek J, Schulz R, Hofmann U, Frantz S, Cochain C, Streckfuß-Bömeke, Ramos GC
An interferon gamma response signature links myocardial aging and immunosenescence
Cardiovasc Res.;119(14):2458-2468
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Sattler S, Campos Ramos G, Ludewig B, Rainer PP
Cardioimmunology: the new frontier!
Eur Heart J. 2023 May 11:ehad230
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van Heeswijk RB, Bauer WR, Bönner F, Janjic JM, Mulder WJM, Schreiber LM, Schwitter J, Flögel U.
Cardiovascular Molecular Imaging With Fluorine-19 MRI: The Road to the Clinic
Circ Cardiovasc Imaging. 2023 Sep;16(9):e014742
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Chen Z, Väth M, Eckstein M, Delgobo M, Ramos G, Frantz S, Hofmann U, Gladow N
Characterization of the effect of the GLUT-1 inhibitor BAY-876 on T cells and macrophages.
Eur J Pharmacol. 2023 Feb 2;175552
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Traub J,Frey A, Störk S.
Chronic Neuroinflammation and Cognitive Decline in Patients with Cardiac Disease: Evidence, Relevance, and Therapeutic Implications.
Life (Basel). 2023 Jan 24;13(2):329
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Cachorro E, Günscht M, Schubert M, Sadek MS, Siegert J, Dutt F, Bauermeister C, Quickert S, Berning H, Nowakowski F, Lämmle S, Firneburg R, Luo X, Künzel SR, Klapproth E, Mirtschink P, Mayr M, Dewenter M, Vettel C, Heijman J, Lorenz K, Guan K, El-Armouche A, Wagner M, Kämmerer S.
CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2
Circ Res. 2023 Feb 17;132(4):400-414
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Weich A, Serfling SE, Yi H, Buck AK, Higuchi T, Werner RA.
Complete Remission Upon Peptide Receptor Radionuclide Therapy in a G2 Pancreatic Neuroendocrine Tumor.
Clin Nucl Med. 2023 Apr 1;48(4):335-336
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de Jonckheere B, Kollotzek F, Münzer P, Göb V, Fischer M, Mott K, Coman C, Troppmair NN, Manke MC, Zdanyte M, Harm T, Sigle M, Kopczynski D, Bileck A, Gerner C, Hoffmann N, Heinzmann D, Assinger A, Gawaz M, Stegner D, Schulze H, Borst O*, Ahrends R
Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation
Nat Cardiovasc Res 2023; 2: 835-852
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Buck AK, Grigoleit GU, Kraus S, Schirbel A, Heinsch M, Dreher N, Higuchi T, Lapa C, Hänscheid H, Samnick S, Einsele H, Serfling SE, Werner RA
C-X-C Motif Chemokine Receptor 4-Targeted Radioligand Therapy in Patients with Advanced T-Cell Lymphoma.
The Journal of Nuclear Medicine (JNM) 2023 Jan; 64(1): 34-39
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Rizzo G, Gropper J, Piollet M, Vafadarnejad E, Rizakou A, Bandi SR, Arampatzi P, Krammer T, DiFabion N, Dietrich O, Arias-Loza AP, Prinz M, Mack M, Schlepckow K, Haass C, Silvestre JS, Zernecke A, Saliba AE, Cochain C
Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction
Cardiovasc Res. 2023 May 2;119(3):772-785.
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Shoykhet M, Dervishi O, Menauer P, Hiermaier M, Moztarzadeh S, Osterloh C, Ludwig RJ, Williams T, Gerull B, Kääb S, Clauss S, Schüttler D, Waschke J, Yeruva S.
EGFR inhibition leads to enhanced desmosome assembly and cardiomyocyte cohesion via ROCK activation
JCI Insight. 2023 Mar 22;8(6):e163763
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Traub J, Schürmann P, Schmitt D, Gassenmaier T, Fette G, Frantz S, Störk S, Beyersdorf N, Boivin-Jahns V, Jahns R, Hofmann U, Frey A
Features of metabolic syndrome and inflammation independently affect left ventricular function early after first myocardial infarction.
International Journal of Cardiology 2023 Jan 1; 370: 43-50
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Walz K, Janz A, Klopocki E, Gerull B
Generation of a CRISPR/Cas9-edited Plakoglobin (JUP) knock-out (JMUi001-A-4) iPSC line to model the cardiac phenotype of arrhythmogenic cardiomyopathy
Stem Cell Res. 2023 Dec;73:103240
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Zhang Y, Vandestienne M, Lavillegrand JR, Joffre J, Santos-Zas I, Lavelle A, Zhong X, Le Goff W, Guérin M, Al-Rifai R, Laurans L, Bruneval P, Guérin C, Diedisheim M, Migaud M, Puel A, Lanternier F, Casanova JL, Cochain C, Zernecke A, Saliba AE, Mokry M, Silvestre JS, Tedgui A, Mallat Z, Taleb S, Lenoir O, Vindis C, Camus SM, Sokol H, Ait-Oufella H
Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy
Nat Commun. 2023 Aug 1;14(1):4622
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Kosmala A, Serfling SE, Schlötelburg W, Lindner T, Michalski K, Schirbel A, Higuchi T, Hartrampf PE, Buck AK, Weich A, Werner RA
High Interobserver Agreement on PSMA PET/CT Even in the Absence of Clinical Data.
Clin Nucl Med. 2023 Mar 1;48(3):207-212.
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Terekhov M, Elabyad IA, Lohr D, Hofmann U, Schreiber LM.
High-resolution imaging of the excised porcine heart at a whole-body 7 T MRI system using an 8Tx/16Rx pTx coil.
MAGMA. 2023 Apr;36(2):279-293.
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Hapke N, Heinrichs M, Ashour D, Vogel E, Hofmann U, Frantz S, Campos Ramos G
Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarction
J Mol Cell Cardiol. 2022 Dec;173:25-29
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Seeling M, Pöhnl M, Kara S, Horstmann N, Riemer C, Wöhner M, Liang C, Brückner C, Eiring P, Werner A, Biburger M, Altmann L, Schneider M, Amon L, Lehmann CHK, Lee S, Kunz M, Dudziak D, Schett G, Bäuerle T, Lux A, Tuckermann J, Vögtle T, Nieswandt B, Sauer M, Böckmann RA, Nimmerjahn F.
Immunoglobulin G-dependent inhibition of inflammatory bone remodeling requires pattern recognition receptor Dectin-1
Immunity. 2023 May 9;56(5):1046-1063.e7
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Kosmala A, Serfling SE, Schlötelburg W, Lindner T, Michalski K, Schirbel A, Higuchi T, Hartrampf PE, Buck AK, Weich A, Werner RA.
Impact of 68 Ga-FAPI-04 PET/CT on Staging and Therapeutic Management in Patients with Digestive System Tumors.
Clinical Nuclear Medicine 2023 Jan 1; 48(1): 35-42
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Liu Z, Hollmann C, Kalanidhi S, Grothey A, Keating S, Mena-Palomo I, Lamer S, Schlosser A, Kaiping A, Scheller C, Sotzny F, Horn A, Nürnberger C, Cejka V, Afshar B, Bahmer T, Schreiber S, Vehreschild JJ, Miljukov O, Schäfer C, Kretzler L, Keil T, Reese JP, Eichner FA, Schmidbauer L, Heuschmann PU, Störk S, Morbach C, Riemekasten G, Beyersdorf N, Scheibenbogen C, Naviaux RK, Williams M, Ariza ME, Prusty BK
Increased circulating fibronectin, depletion of natural IgM and heightened EBV, HSV-1 reactivation in ME/CFS and long COVID
medRxiv. 2023 Jun 29;2023.06.23.23291827
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Zernecke A, Erhard F, Weinberger T, Schulz C, Ley K, Saliba AE, Cochain C.
Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis
Cardiovasc Res. 2023 Jul 6;119(8):1676-1689
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Traub J, Schließer M, Morbach C, Frantz S, Pham M, Störk S, Stoll G, Frey A, Neugebauer H
Internal carotid artery blood flow and pulsatility index in cognitively impaired people with chronic heart failure
ESC Heart Fail. 2023 Jul 4
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Hartrampf PE, Kosmala A, Serfling SE, Bundschuh L, Higuchi T, Lapa C, Rowe SP, Matsusaka Y, Weich A, Buck AK, Bundschuh RA, Werner RA.
Interobserver Agreement Rates on C-X-C Motif Chemokine Receptor 4-Directed Molecular Imaging and Therapy.
Clin Nucl Med. 2023 Mar 22
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Kosmala A, Seifert S, Schneid S, Dreher N, Higuchi T, Weich A, Serfling SE, Hartrampf PE, Einsele H, Buck AK, Topp MS, Duell J, Werner RA.
Lymphoma-Sink Effect in Marginal Zone Lymphoma Based on CXCR4-Targeted Molecular Imaging
Mol Imaging Biol. 2023 Jun 7
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Chen R, Buchmann S, Kroth A, Arias-Loza AP, Kohlhaas M, Wagner N, Grüner G, Nickel A, Cirnu A, Williams T, Maack C, Ergün S, Frantz S, Gerull B.
Mechanistic Insights of the LEMD2 p.L13R Mutation and Its Role in Cardiomyopathy
Circ Res. 2023 Jan 20;132(2):e43-e58.
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Chowdhury A, Boshnakovska A, Aich A, Methi A, Vergel Leon AM, Silbern I, Lüchtenborg C, Cyganek L, Prochazka J, Sedlacek R, Lindovsky J, Wachs D, Nichtova Z, Zudova D, Koubkova G, Fischer A, Urlaub H, Brügger B, Katschinski DM, Dudek J, Rehling P.
Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome
EMBO Mol Med 15(9):e17399
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Wu H, Zhao X, Hochrein SM, Eckstein M, Gubert GF, Knöpper K, Mansilla AM, Öner A, Doucet-Ladevèze R, Schmitz W, Ghesquière B, Theurich S, Dudek J, Gasteiger G, Zernecke A, Kobold S, Kastenmüller W, Vaeth M
Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming
Nat Commun.;14(1):6858
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Weissman D, Maack C.
Mitochondrial function in macrophages controls cardiac repair after myocardial infarction
J Clin Invest. 2023 Feb 15;133(4):e167079
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Kosmala A, Serfling SE, Michalski K, Lindner T, Schirbel A, Higuchi T, Hartrampf PE, Derlin T, Buck AK, Weich A, Werner RA
Molecular imaging of arterial fibroblast activation protein: association with calcified plaque burden and cardiovascular risk factors
Eur J Nucl Med Mol Imaging. 2023 May 6
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Lerchenmüller C, Zelarayan L, Streckfuss-Bömeke K, Gimenez MR, Schnabel R, Hashemi D, Baldus S, Rudolph TK, Morbach C.
Moving toward gender equity in the cardiology and cardiovascular research workforce in Germany: a report from the German Cardiac Society
Eur Heart J Open. 2023 Mar 29;3(2):oead034
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Janz A, Walz K, Cirnu A, Surjanto J, Urlaub D, Leskien M, Kohlhaas M, Nickel A, Brand T, Nose N, Wörsdörfer P, Wagner N, Higuchi T, Maack C, Dudek J, Lorenz K, Klopocki E, Ergün S, Duff HJ, Gerull B
Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes
Mol Metab.:101859
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Delgobo M, Weiß E, Ashour D, Richter L, Popiolkowski L, Arampatzi P, Stangl V, Arias-Loza P, Mariotti-Ferrandiz E, Rainer PP, Saliba AE, Ludewig B, Hofmann U, Frantz S and Campos Ramos G
Myocardial Milieu Favors Local Differentiation of Regulatory T Cells
Circulation Research. 2023;132:565–582
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Ramos GC, Frantz S, Hofmann U.
Myosin-specific T-cells in myocardial diseases revisited
Circulation, 2023 cvad068
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Weiss LJ, Drayss M, Mott K, Beck S, Unsin D, Just B, Speer CP, Hartel C, Andres O, Schulze H
Ontogenesis of functional platelet subpopulations from preterm and term neonates to adulthood: The PLINIUS study
Blood Adv 7(16): 4334-4348
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Weich A, Serfling SE, Rowe SP, Solnes LB, Buck AK, Higuchi T, Werner RA.
Partial Response Upon Peptide Receptor Radionuclide Therapy in a Highly Proliferative Pancreatic Neuroendocrine Tumor
Clin Nucl Med. 2023 Mar 16
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Beck S, Öftering P, Li R, Hemmen K, Nagy M, Wang Y, Zarpellon A, Schuhmann MK, Stoll G, Ruggeri ZM, Heinze KG, Heemskerk JWM, Ruf W, Stegner D, Nieswandt B
Platelet glycoprotein V spatio-temporally controls fibrin formation
Nat Cardiovasc Res. 2023 Apr;2(4):368-382
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Schütte JP, Manke MC, Hemmen K, Münzer P, Schörg BF, Ramos GC, Pogoda M, Dicenta V, Hoffmann SHL, Pinnecker J, Kollotzek F, Zdanyte M, Mueller KAL, Singh Y, Mack AF, Pichler B, Lang F, Nieswandt B, Gawaz M, Heinze KG, Casadei N, Borst O
Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia.
Circ Res. 2023 Mar 31
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Morbach C, Gelbrich G, Schreckenberg M, Hedemann M, Pelin D, Scholz N, Miljukov O, Wagner A, Theisen F, Hitschrich N, Wiebel H, Stapf D, Karch O, Frantz S, Heuschmann PU, Störk S
Population data-based federated machine learning improves automated echocardiographic quantification of cardiac structure and function: the Automatisierte Vermessung der Echokardiographie project
Eur Heart J Digit Health. 2023 Nov 15;5(1):77-88
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Morbach C, Beyersdorf N, Moser N, Pelin D, Afshar B, Ramos G, Kerkau T, Kaiser E, Lamers J, Pätkau J, Sahiti F, Albert J, Güder G, Ertl G, Angermann CE, Frantz S, Hofmann U, Jahns R, Jahns V, Störk S
Prevalence of anti-beta-1 antibody 6 months after hospitalization for acute heart failure predicts adverse outcome
ESC Heart Fail. 2023 Sep 8
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Göpfert D, Traub J, Sell R, Homola GA, Vogt M, Pham M, Frantz S, Störk S, Stoll G, Frey A.
Profiles of cognitive impairment in chronic heart failure-A cluster analytic approach
Front Hum Neurosci. 2023 Apr 20
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Werner RA, Hartrampf PE, Fendler WP, Serfling SE, Derlin T, Higuchi T, Pienta KJ, Gafita A, Hope TA, Pomper MG, Eiber M, Gorin MA, Rowe SP.
Prostate-specific Membrane Antigen Reporting and Data System Version 2.0
Eur Urol. 2023 Jul 4;S0302-2838(23)02903-2
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Tutov A, Chen X, Werner RA, Mühlig S, Zimmermann T, Nose N, Koshino K, Lapa C, Decker M, Higuchi T.
Rationalizing the Binding Modes of PET Radiotracers Targeting the Norepinephrine Transporter.
Pharmaceutics. 2023 Feb 17;15(2):690
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Higuchi T, Hartrampf PE, Buck AK, Pomper MG, Rowe SP, Serfling SE, Werner RA
Role of Functional SPECT and PET in Renal Emergencies
Semin Nucl Med. 2023 May 24:S0001-2998(23)00031-4
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Serfling SE, Hartrampf PE, Zhi Y, Higuchi T, Kosmala A, Serfling J, Schirbel A, Hörning A, Buck AK, Weich A, Werner RA.
Somatostatin Receptor-Directed PET/CT for Therapeutic Decision-Making and Disease Control in Patients Affected With Small Cell Lung Cancer.
Clin Nucl Med. 2023 Apr 1;48(4):309-314
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Li Y, Díaz I, Martín-Valls G, Beyersdorf N, Mateu E
Systemic CD4 cytotoxic T cells improve protection against PRRSV-1 transplacental infection.
Front Immunol. 2023 Jan 17;13:1020227
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Sequeira V, Batzner A, Maack C
Targeting mitochondria in hypertrophic cardiomyopathy
Eur Heart J. 2023 Apr 1;44(13):1186-1188
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Werner RA, Lütje S, Habacha B, Bundschuh L, Higuchi T, Buck AK, Kosmala A, Lapa C, Essler M, Lodge MA, Pienta KJ, Eisenberger MA, Markowski MC, Gorin MA, Pomper MG, Rowe SP, Bundschuh RA
Test-retest repeatability of organ uptake on PSMA-targeted 18 F-DCFPyL PET/CT in patients with prostate cancer
Prostate. 2023 May 21
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Campos Ramos G, Hudecek M
The era of in vivo T cell engineering
Med. 2022 Feb 11;3(2):85-86
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Bazgir F, Nau J, Nakhaei-Rad S, Amin E, Wolf MJ, Saucerman JJ, Lorenz K, Ahmadian MR
The Microenvironment of the Pathogenesis of Cardiac Hypertrophy>
Cells. 2023 Jul 4;12(13):1780
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Buck AK, Serfling SE, Kraus S, Samnick S, Dreher N, Higuchi T, Rasche L, Einsele H, Werner RA.
Theranostics in Hematooncology
J Nucl Med. 2023 Jun 8:jnumed.122.265199
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Schreiber LM, Lohr D, Baltes S, Vogel U, Elabyad IA, Bille M, Reiter T, Kosmala A, Gassenmaier T, Stefanescu MR, Kollmann A, Aures J, Schnitter F, Pali M, Ueda Y, Williams T, Christa M, Hofmann U, Bauer W, Gerull B, Zernecke A, Ergün S, Terekhov M
Ultra-high field cardiac MRI in large animals and humans for translational cardiovascular research.
Front Cardiovasc Med. 2023 May 1
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Weiss LJ, Drayss M, Manukjan G, Zeitlhöfler M, Kleiss J, Weigel M, Herrmann J, Mott K, Beck S, Burkard P, Lâm TT, Althaus K, Bakchoul T, Frantz S, Meybohm P, Nieswandt B, Weismann D, Schulze H
Uncoupling of platelet granule release and integrin activation suggests GPIIb/IIIa as a therapeutic target in COVID-19
Blood Adv. 2023 Jun 13;7(11):2324-2338
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Higuchi T, Werner RA
Unfolding the cardioprotective potential of sigma-1 receptor-directed molecular imaging
J Nucl Cardiol. 2023 Apr;30(2):662-664
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Klingenberg R, Holtkamp F, Grün D, Frey A, Jahns V, Jahns R, Gassenmaier T, Hamm CW, Frantz S, Keller T
Use of serial changes in biomarkers vs. baseline levels to predict left ventricular remodelling after STEMI.
ESC Heart Failure 2023 Feb; 10(1): 432-441
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Zernecke A, Erhard F, Weinberger T, Schulz C, Ley K, Saliba AE, Cochain C
Integrated single-cell analysis based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis.
Cardiovascular Research 2022 Oct 3; cvac161
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Chen X, Werner RA, Koshino K, Nose N, Mühlig S, Rowe SP, Pomper MG, Lapa C, Decker M, Higuchi T.
A Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity – Introducing High NET Affinity PET Probe 18F-AF78.
Theranostics 2022 May 24; 12(9): 4446-4458
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Dolejsi T, Delgobo M, Schuetz T, Tortola L, Heinze KG, Hofmann U, Frantz S, Bauer A, Ruschitzka F, Penninger JM, Campos Ramos G, Haubner BJ.
Adult T-cells impair neonatal cardiac regeneration.
European Heart Journal 2022 Jul 21; 43(28): 2698-2709
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Brown HC, Beck S, Navarro S, Di Y, Soriano Jerez EM, Kaczmarzyk J, Thomas SG, Mirakaj V, Watson SP, Nieswandt B, Stegner D
Antibody-mediated depletion of human CLEC-2 in a novel humanised mouse model.
Blood Advances 2022 Aug: 2021006463
No abstract available
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Tolstik E, Ali N, Guo S, Ebersbach P, Möllmann D, Arias-Loza P, Dierks J, Schuler I, Freier E, Debus J, Baba HA, Nordbeck P, Bocklitz T, Lorenz K.
CARS Imaging Advances Early Diagnosis of Cardiac Manifestation of Fabry Disease.
International Journal of Molecular Sciences 2022 May 11; 23(10): 5345
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Lambertini A, Hartrampf PE, Higuchi T, Serfling SE, Meybohm P, Schirbel A, Buck AK, Werner RA.
CXCR4-targeted molecular imaging after severe SARS-Cov-2 infection.
European Journal of Nuclear Medicine and Molecular Imaging 2022 Dec; 50(1): 228-229
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Werner RA, Martinez RB, Marcus C, Kruse MJ, Sheikhbahaei S, Solnes LB, Higuchi T, Javadi MS, Rowe SP.
Diagnostic performance of IQ·SPECT with high-speed scanning: A preliminary quality control study in obese patients.
Journal of Nuclear Cardiology. 2022 Dec; 29(6): 3443-3449
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Rizzo G, Gropper J, Piollet M, Vafadarnejad E, Rizakou A, Bandi SR, Arampatzi P, Krammer T, DiFabion N, Dietrich O, Arias-Loza AP, Prinz M, Mack M, Schlepckow K, Haass C, Silvestre JS, Zernecke A, Saliba AE, Cochain C.
Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction.
Cardiovascular Research 2022 Aug 11; cvac113
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Werner RA, Higuchi T, Nose N, Toriumi F, Matsusaka Y, Kuji I, Kazuhiro K.
Generative adversarial network-created brain SPECTs of cerebral ischemia are indistinguishable to scans from real patients.
Scientific Reports 2022 Nov 5; 12(1): 18787
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Brodehl A, Gerull B.
Genetic Insights into Primary Restrictive Cardiomyopathy.
Journal of Clinical Medicine 2022 Apr 8; 11(8): 2094
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Hapke N, Heinrichs M, Ashour D, Vogel E, Hofmann U, Frantz S, Campos Ramos G
Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarction.
Journal of Molecular and Cellular Cardiology (JMCC) 2022 Dec; 173: 25-29
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Bertero E, Dudek J, Cochain C, Delgobo M, Ramos G, Gerull B, Higuchi T, Vaeth M, Zernecke A, Frantz S, Hofmann U, Maack C
Immuno-metabolic interfaces in cardiac disease and failure
Cardiovasc Res 2022 Jan 7;118(1):37-52
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Frantz S, Hundertmark MJ, Schulz-Menger J, Bengel FM, Bauersachs J
Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies.
European Heart Journal 2022 Jul 14; 43(27): 2549-2561
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Petzold T, Zhang Z, Ballesteros I, Saleh I, Polzin A, Thienel M, Liu L, Ul Ain Q, Ehreiser V, Weber C, Kilani B, Mertsch P, Götschke J, Cremer S, Fu W, Lorenz M, Ishikawa-Ankerhold H, Raatz E, El-Nemr S, Görlach A, Marhuenda E, Stark K, Pircher J, Stegner D, Gieger C, Schmidt-Supprian M, Gaertner F, Almendros I, Kelm M, Schulz C, Hidalgo A
Massberg S. Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease
Immunity 2022; 55(12): 2285-2299
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Weiß E, Ramos GC, Delgobo M.
Myocardial-Treg Crosstalk: How to Tame a Wolf.
Frontiers in Immunology 2022 May 25; 13: 914033
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Jeson Sangaralingham S, Kuhn M, Cannone V, Chen HH, Burnett JC.
Natriuretic peptide pathways in heart failure - further therapeutic possibilities.
Cardiovascular Research 2022 Aug 25: 118(18): 3416-3433
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Petzold T, Zhang Z, Ballesteros I, Saleh I, Polzin A, Thienel M, Liu L, Ul Ain Q, Ehreiser V, Weber C, Kilani B, Mertsch P, Götschke J, Cremer S, Fu W, Lorenz M, Ishikawa-Ankerhold H, Raatz E, El-Nemr S, Görlach A, Marhuenda E, Stark K, Pircher J, Stegner D, Gieger C, Schmidt-Supprian M, Gaertner F, Almendros I, Kelm M, Schulz C, Hidalgo A, Massberg S.
Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.
Immunity 2022 Dec 13; 55(12): 2285-2299
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Matsusaka Y, Werner RA, Arias-Loza P, Nose N, Sasaki T, Chen X, Lapa C, Higuchi T.
Performance Evaluation of a Preclinical SPECT Scanner with a Collimator Designed for Medium-Sized Animals.
Molecular Imaging 2022 Jul 16; 2022: 9810097Z
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Lee J, Olivieri C, Ong C, Masterson LR, Gomes S, Lee BS, Schaefer F, Lorenz K, Veglia G, Rosner MR
Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop
Proc Natl Acad Sci U S A. 2022:119(25):e2121867119
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Tolstik E, Gongalsky MB, Dierks J, Brand T, Pernecker M, Pervushin NV, Maksutova DE, Gonchar KA, Samsonova JV, Kopeina G, Sivakov V, Osminkina LA, Lorenz K
NEKAR study group. Raman and fluorescence micro-spectroscopy applied for the monitoring of sunitinib-loaded porous silicon nanocontainers in cardiac cells.
Frontiers of Pharmacology 2022 Aug 9; 13: 962763
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Delgobo M, Weiß E, Ashour D, Popiolkowski L, Arampatzi P, Stangl V, Arias-Loza P, Rainer P, Saliba AE, Ludewig B, Hofmann U, Frantz S, Campos Ramos G
Rapid differentiation of regulatory CD4+ T cells in the infarcted myocardium blunts in situ inflammation.
bioRxiv 2022 Mar 27
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Traub J, Otto M, Sell R, Göpfert D, Homola G, Steinacker P, Oeckl P, Morbach C, Frantz S, Pham M, Störk S, Stoll G, Frey A
Serum phosphorylated tau protein 181 and neurofilament light chain in cognitively impaired heart failure patients.
Alzheimers´ Resarch and Therapy 2022 Oct 10; 14(1): 149
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Traub J, Grondey K, Gassenmaier T, Schmitt D, Fette G, Frantz S, Boivin-Jahns V, Jahns R, Störk S, Stoll G, Reiter T, Hofmann U, Weber MS, Frey A
Sustained Increase in Serum Glial Fibrillary Acidic Protein after First ST-Elevation Myocardial Infarction.
International Journal of Molecular Sciences 2022 Sep 7; 23(18): 10304
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Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, Künzel SR, Kämmerer S, Günscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L , Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M, El-Armouche A
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
Nature Communications 2022 Dec 10; 13(1): 7648
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Ramos CG, Hudecek M
The era of in vivo T cell engineering.
Med (N Y) 2022 Feb 11; 3(2): 85-86
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Hochrein SM, Wu H, Eckstein M, Arrigoni L, Herman JS, Schumacher F, Gerecke C, Rosenfeldt M, Grün D, Kleuser B, Gasteiger G, Kastenmüller W, Ghesquière B, Van den Bossche J, Abel ED, Vaeth M
The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming.
Cell Metabolism 2022 Apr 5; 34(4): 516-532.e11
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Weiss LJ, Drayss M, Mott K, Droste M, Just B, Arold AM, Nieswandt B, Weismann D, Stegner D, Schulze H
The homophilic CD84 receptor is upregulated on platelets in COVID-19 and sepsis.
Thrombosis Research 2022 Dec; 220: 121-124
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Merches K, Breunig L, Fender J, Brand T, Bätz V, Idel S, Kollipara L, Reinders Y, Sickmann A, Mally A, Lorenz K.
The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro.
Archives of Toxicology 2022 Aug; 96(8): 2341-2360
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Higuchi T, Serfling SE, Rowe SP, Werner RA.
Therapeutic Effects of Lipid Lowering Medications on Myocardial Blood Flow, Inflammation, and Sympathetic Nerve Activity Using Nuclear Techniques.
Current Cardiology Reports 2022 Dec; 24(12): 1849-1853
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Erhard F, Saliba AE, Lusser A, Toussaint C, Hennig T, Prusty BK, Kirschenbaum D, Abadie K, Miaka EA, Friedel CC, Amit I, Micura R, Dölken L
Time-resolved single-cell RNA-seq using metabolic RNA labelling.
Nature Revies Methods Primers 2022 Sep 29: 2(77)
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Weiss LJ, Drayss M, Manukjan G, Zeitlhoefler M, Kleiss J, Weigel ML, Herrmann J, Mott K, Beck S, Burkard P, Lam TT, Althaus K, Bakchoul T, Frantz S, Meybohm P, Nieswandt B, Weismann D, Schulze H
Uncoupling of platelet granule release and integrin activation suggests GPIIb/IIIa as therapeutic target in COVID-19
Blood Adv. 13;7(11):2324-2338
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Higuchi T, Werner RA
Unfolding the cardioprotective potential of sigma-1 receptor-directed molecular imaging.
Editorial Journal of Nuclear Cardiology 2022 Aug 4
No abstract available
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Klingenberg R, Holtkamp F, Grün D, Frey A, Jahns V, Jahns R, Gassenmaier T, Hamm CW, Frantz S, Keller T.
Use of serial changes in biomarkers vs. baseline levels to predict left ventricular remodelling after STEMI
ESC Heart Fail. 2022 Oct 21.
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