The project myocardium is investigating the central role of the heart muscle within the cardiovascular system during the development of heart failure. The focus is to understand cellular mechanisms leading to heart failure as well as developing novel methods to illustrate the regular heart function but also the changes occurring in heart failure.

The project heart and brain is focussing on the complex interactions between heart and brain. One essential component of this interplay (here as an example) is the sympathetic nerve. It is activated in the central brain and has important impact on heart function. Vice versa, heart function also regulates the blood perfusion of the brain. The physiological and pathological interactions between these organs are not limited to this mechanism.

The project heart, metabolism and other organs is investigating the role of different organs in the pathogenesis of heart failure but also the impact of co-morbidities.