Clinical Trials

In clinical trials, new diagnostic and therapeutic methods as well as hypotheses about the predictability of therapy effectiveness are tested and validated. Within the scope of these trials, we cooperate with other hospitals, universities, and general practitioners.

Protect AD

It is normal to be afraid of some things. But some people's fears are so intense and severe that their daily lives are hindered - they suffer from an anxiety disorder. It can be quite difficult to find an appropriate and suitable therapy for such a disorder. Patients are often faced with long waiting times and therapies of limited effectiveness.

Our goal is an intense short-term therapy which is not only available for all patients but also has a high long-term effectiveness.

Please find more information

  • in the study leaflet (in German)
  • on the webpage of the third-party funded project Protect AD

Non-invasive brain stimulation in the psychotherapy of anxiety disorders (Pan_VR)

Anxiety disorders are among the most common mental illnesses. With the help of cognitive behavioural therapy (CBT) for anxiety disorders, great improvements can already be achieved, but not all patients benefit sufficiently from this. As a newer method for supplementing or optimizing the therapy of anxiety disorders, our study will use the example of fear of heights to test for the first time whether an activation of a specific brain region induced by a type of magnetic field significantly improves subsequent exposure therapy compared to placebo stimulation.

All study participants receive two exposure treatments in virtual reality. The perceived anxiety is recorded by a questionnaire before and after the therapy. In addition, a follow-up examination is carried out after 6 months.

Further information can be found on the page of the corresponding grant-funded project.

Treatment of major depressive disorders with bilateral theta-burst stimulation (TBS-D)

Depression is one of the most common and serious psychiatric disorders. In this study, the effectiveness of theta-burst stimulation (a form of magnetic stimulation) as an augmentative treatment for depression will be tested for its clinical efficacy.

A total of 236 patients will be enrolled in this study who will receive active or placebo stimulation. The treatment is carried out as an additional therapy on every working day for 6 weeks. The sustainability will be evaluated by 1 and 3 month follow-ups.

Further information can be found on the page of the corresponding grant-funded project.

P4D study

Fighting depression with personalised medicine

The project entitled "Personalised, predictive, precise and preventive medicine to improve the early detection, diagnosis, treatment and prevention of depressive disorders" (P4D) is the largest research project to date in Germany to improve the quality of depression treatment.

Further information can be found on the website of the associated grant-funded project

Computer-assisted risk evaluation in the early detection of psychotic illnesses (CARE)

CARE stands for computer-assisted risk evaluation and risk-adapted treatment in cases of increased risk of developing psychosis.
CARE is being carried out as a multi-centre, randomised controlled study, i.e. the people taking part are randomly assigned to the new clinical form of care or to the existing standard care. The aim is to use these measures to prevent the onset of psychosis and/or improve social and occupational performance.

What are psychoses?
sychoses describe a group of mental disorders that can occur independently, but also in conjunction with depressive or manic disorders or with the use of psychotropic substances. What the psychoses have in common, for example, is that the ego-environment boundary becomes blurred, the perception and interpretation of the world changes completely and changes in thinking can occur. 

What is an increased risk of psychosis?
To date, we know that psychoses develop gradually over an average of 5.5 years, often beginning in adolescence or young adulthood in the form of distressing psychological symptoms. Those affected often seek help early on, but rarely find a specialised treatment offer promptly, as the first symptoms are usually unspecific and are not always recognised immediately.

Who can take part in CARE?
People between the ages of 16 and 40 who are at an increased risk of developing a psychotic disorder can take part in CARE. The study is not open to People with a pre-existing psychosis, severe depression with psychotic symptoms or with addictive disorders.

You can find more information  

tDCS treatment for ADHD

In this study tDCS will be reviewed as a non-invasive brain stimulation procedure in the sole or add-on treatment of attention-deficite hyperactivity disorder in adults. Currently subjects with already diagnosed ADHD are needed.

Interested parties should contact our study nurse:
Christiane Rieß