Current Clinical Trials

Catatonia is a disorder affecting movement and volition that can occur in the context of various mental illnesses. 

In this study, the course of this disorder is examined in greater detail using clinical scales, motor tests, and imaging.
Flyer about the study: Medical Study on Catatonia
 

In our current studies, we use smartphone-based surveys and mobile sensors to investigate the influence of everyday social interactions across various patient groups on a transdiagnostic basis (e.g., in patients with psychotic disorders or mood disorders).

Mental illness - therapy - development

The aim of this study is to investigate the links between parental psychological stress and illness in the period around birth and child development. The study should also help to improve the diagnosis and treatment of mental illnesses around birth and thus promote healthy child development.

Further information can be found at the corresponding PETE flyer and on the page of the associated grant-funded project.

Mental illnesses during pregnancy and breastfeeding are not uncommon and, if they are not treated or are treated too late, can lead to further serious problems for parents and children. Studies show that many of those affected are not diagnosed at an early stage and consequently do not receive adequate treatment or counseling.

As part of the UPlusE study, an app-based screening is being established for the early detection of depressive developments, psychosocial stress and problems in the parent-child relationship. Both (expectant) mothers and fathers are regularly surveyed at the end of pregnancy and in the first year of the child's life. These surveys are linked to the preventive check-ups at the gynecologist or U-examinations at the pediatrician. On the basis of this data, help is provided to those affected in line with their needs.

A digital network of gynecologists, pediatricians, psychiatrists, psychotherapists and psychosomaticians including obstetrics clinics and "early help" (Offers for families with children up to the age of three) should enable complex interdisciplinary and cross-sectoral care.

The aim of the study, which has received 4.6 million euros in funding from the Innovation Fund of the Joint Federal Committee, is to ensure that screening is included in the standard care provided by statutory health insurance funds and thus improve health in the long term.

Further information can be found at www.upluse.de, the corresponding UPlusE flyer and on the page of the associated grant-funded project.

Anxiety disorders are among the most common mental illnesses. With the help of cognitive behavioral therapy (CBT) for anxiety disorders, great progress can already be achieved, but many patients report that anxiety symptoms return after successful therapy.

In this study, we are investigating whether anxiety memory can be permanently erased from memory using transcanal magnetic stimulation.

Further information can be found on the page of the corresponding grant-funded project.

For more information, please visit the page for the related external-funding project.

Fighting depression with personalised medicine

The project entitled "Personalised, predictive, precise and preventive medicine to improve the early detection, diagnosis, treatment and prevention of depressive disorders" (P4D) is the largest research project to date in Germany to improve the quality of depression treatment.

Further information can be found on the website of the associated grant-funded project

In this study tDCS will be reviewed as a non-invasive brain stimulation procedure in the sole or add-on treatment of attention-deficite hyperactivity disorder in adults. Currently subjects with already diagnosed ADHD are needed.

Interested parties should contact our study nurse:
Christiane Rieß
riess_@ukw.de

Around one in five older people is affected by depressive symptoms; the risk is even higher for people living at home and those with several illnesses at the same time (multimorbidity). However, when transitioning from geriatric psychiatric or geriatric inpatient or day clinic treatment to outpatient care, there is often a lack of support services to consolidate the therapeutic successes already achieved and prevent a renewed deterioration in health.

The aim of the BRIDGE project is to evaluate a new form of care to reduce depression in older, multimorbid people. The expertise of psychotherapeutic, exercise therapy and nursing specialists will be utilized. Those affected are encouraged and empowered to engage in physical activity and a positive daily routine. The program is planned for three months and follows a standardized modular treatment manual for behavioral and physical activation, whereby the specific design takes personal preferences into account. The care offered includes, for example, learning physical exercises based on the individual abilities of the participants, as well as links to regionally available health services. The care begins during inpatient or semi-inpatient treatment and is then continued at home by outreach nurses; in addition, the intervention is also made possible via video in the home environment.

BRIDGE is a joint project under the consortium leadership of the University Medical Center Mainz with study centers in Bavaria, Hesse, Rhineland-Palatinate and Saarland.

Project start for patients is 1.1.2025

Further information: Innovationsausschuss beim Gemeinsamen Bundesausschuss