Publikationen

Scheller I, Beck S, Göb V, Gross C, Neagoe RAI, Aurbach K, Bender M, Stegner D, Nagy Z, Nieswandt B. (2022) 
Thymosin beta4 is essential for thrombus formation by controlling the G-actin/F-actin equilibrium in platelets.
Haematologica. 2022 Dec 1;107(12):2846-2858. doi: 10.3324/haematol.2021.278537.
Zur Publikation.

Weiss LJ, Drayss M, Mott K, Droste M, Just B, Arold AM, Nieswandt B, Weismann D, Stegner D, Schulze H. (2022)
The homophilic CD84 receptor is upregulated on platelets in COVID-19 and sepsis.
Thromb Res. 2022 Dec;220:121-124. doi: 10.1016/j.thromres.2022.10.011. Epub 2022 Oct 22. Zur Publikation.

Currie SM, Stegmeyer RI, Mildner K, Breitsprecher L, Zeuschner D, Psathaki OE, Schäfer K, Wilkens M, Volkery S, Nieswandt B, Vestweber D. (2022)
Confocal Real-Time Analysis of Cutaneous Platelet Recruitment during Immune Complex‒Mediated Inflammation.
J Invest Dermatol. 2022 Oct;142(10):2724-2732.e3. doi: 10.1016/j.jid.2022.03.011. Epub 2022 Mar 31. Zur Publikation.

Englert M, Aurbach K, Becker IC, Gerber A, Heib T, Wackerbarth LM, Kusch C, Mott K, Araujo GHM, Baig AA, Dütting S, Knaus UG, Stigloher C, Schulze H, Nieswandt B, Pleines I, Nagy Z. (2022)
Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice.
Blood Adv. 2022 Sep 13;6(17):5184-5197. doi: 10.1182/bloodadvances.2021006545.
Zur Publikation.

Weiss LJ, Drayss M, Manukjan G, Zeitlhöefler MJ, Kleiss J, Weigel ML, Herrmann J, Mott K, Beck S, Burkard P, Lam TT, Althaus K, Bakchoul T, Frantz S, Meybohm P, Nieswandt B, Weismann D, Schulze H. (2022)
Uncoupling of platelet granule release and integrin activation suggests GPIIb/IIIa as therapeutic target in COVID-19.
Blood Adv. 2022 Sep 2:bloodadvances.2022008666. doi: 10.1182/bloodadvances.2022008666. Online ahead of print.
Zur Publikation.

Stoll G, Schuhmann MK, Nieswandt B, Kollikowski AM, Pham M. (2022)
An intravascular perspective on hyper-acute neutrophil, T-cell and platelet responses: Similarities between human and experimental stroke.
J Cereb Blood Flow Metab. 2022 Sep;42(9):1561-1567. doi: 10.1177/0271678X221105764. Epub 2022 Jun 8.
Zur Publikation.

Brown HC, Beck S, Navarro S, Di Y, Soriano Jerez EM, Kaczmarzyk J, Thomas SG, Mirakaj V, Watson SP, Nieswandt B, Stegner D. (2022)
Antibody-mediated depletion of human CLEC-2 in a novel humanised mouse model.
Blood Adv. 2022 Aug 31:bloodadvances.2021006463. doi: 10.1182/bloodadvances.2021006463. Online ahead of print.
Zur Publikation.

Bieber M, Schuhmann MK, Bellut M, Stegner D, Heinze KG, Pham M, Nieswandt B, Stoll G. (2022) 
Blockade of Platelet Glycoprotein Ibα Augments Neuroprotection in Orai2-Deficient Mice during Middle Cerebral Artery Occlusion.
Int J Mol Sci. 2022 Aug 22;23(16):9496. doi: 10.3390/ijms23169496.
Zur Publikation.

Heil HS, Aigner M, Maier S, Gupta P, Evers LMC, Göb V, Kusch C, Meub M, Nieswandt B, Stegner D, Heinze KG. (2022)
Mapping densely packed αIIbβ3 receptors in murine blood platelets with expansion microscopy.  
Platelets. 2022 Aug 18;33(6):849-858. doi: 10.1080/09537104.2021.2023735. Epub 2022 Feb 2
Zur Publikation.

Navarro S, Starke A, Heemskerk JWM, Kuijpers MJE, Stegner D, Nieswandt B. (2022) 
Targeting of a Conserved Epitope in Mouse and Human GPVI Differently Affects Receptor Function.
Int J Mol Sci. 2022 Aug 3;23(15):8610. doi: 10.3390/ijms23158610.
Zur Publikation.

Seyhan M, Ungethüm K, Schuhmann MK, Mackenrodt D, Rücker V, Montellano FA, Wiedmann S, Rath D, Geisler T, Nieswandt B, Kraft P, Kleinschnitz C, Heuschmann PU. (2022)
Feasibility of platelet marker analysis in ischemic stroke patients and their association with one-year outcome. A pilot project within a subsample of the Stroke Induced Cardiac Failure in Mice and Men (SICFAIL) cohort study.
Platelets. 2022 Jul 4;33(5):772-780. doi: 10.1080/09537104.2021.2002834. Epub 2021 Dec 7. 
Zur Publikation.

Kollikowski AM, Pham M, März AG, Papp L, Nieswandt B, Stoll G, Schuhmann MK. (2022)
Platelet Activation and Chemokine Release Are Related to Local Neutrophil-Dominant Inflammation During Hyperacute Human Stroke.
Transl Stroke Res. 2022 Jun;13(3):364-369. doi: 10.1007/s12975-021-00938-w. Epub 2021 Aug 28.
Zur Publikation. 

Mwiza JMN, Lee RH, Paul DS, Holle LA, Cooley BC, Nieswandt B, Schug WJ, Kawano T, Mackman N, Wolberg AS, Bergmeier W. (2022)
Both G protein-coupled and immunoreceptor tyrosine-based activation motif receptors mediate venous thrombosis in mice.
Blood. 2022 May 26;139(21):3194-3203. doi: 10.1182/blood.2022015787.
Zur Publikation.

Becker IC, Nagy Z, Manukjan G, Haffner-Luntzer M, Englert M, Heib T, Vögtle T, Gross C, Bharti R, Dietrich S, Mott K, Heck J, Stegmaier S, Baranowsky A, Schinke T, Schlegel N, Heckel T, Stegner D, Pleines I, Ignatius A, Schulze H, Nieswandt B. (2022)
G6b-B regulates an essential step in megakaryocyte maturation.
Blood Adv. 2022 May 24;6(10):3155-3161. doi: 10.1182/bloodadvances.2021006151.
Zur Publikation.

Lee RH, Ghalloussi D, Harousseau GL, Kenny JP, Kramer PA, Proamer F, Nieswandt B, Flick MJ, Gachet C, Casari C, Eckly A, Bergmeier W. (2022)
Rasa3 deficiency minimally affects thrombopoiesis but promotes severe thrombocytopenia due to integrin-dependent platelet clearance.
JCI Insight. 2022 Apr 22;7(8):e155676. doi: 10.1172/jci.insight.155676.
Zur Publikation.

Nording H, Sauter M, Lin C, Steubing R, Geisler S, Sun Y, Niethammer J, Emschermann F, Wang Y, Zieger B, Nieswandt B, Kleinschnitz C, Simon DI, Langer HF. (2022)
Activated Platelets Upregulate β2 Integrin Mac-1 (CD11b/CD18) on Dendritic Cells, Which Mediates Heterotypic Cell-Cell Interaction.
J Immunol. 2022 Apr 1;208(7):1729-1741. doi: 10.4049/jimmunol.2100557. Epub 2022 Mar 11.
Zur Publikation. 

Neagoe RAI, Gardiner EE, Stegner D, Nieswandt B, Watson SP, Poulter NS. (2022) 
Rac Inhibition Causes Impaired GPVI Signalling in Human Platelets through GPVI Shedding and Reduction in PLCγ2 Phosphorylation.
Int J Mol Sci. 2022 Mar 29;23(7):3746. doi: 10.3390/ijms23073746.
Zur Publikation.

Lickert S, Kenny M, Selcuk K, Mehl JL, Bender M, Früh SM, Burkhardt MA, Studt JD, Nieswandt B, Schoen I, Vogel V. (2022)
Platelets drive fibronectin fibrillogenesis using integrin αIIbβ3.
Sci Adv. 2022 Mar 11;8(10):eabj8331. doi: 10.1126/sciadv.abj8331. Epub 2022 Mar 11.
Zur Publikation.

Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Chauhan A, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. (2022)
Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.
Nat Med. 2022 Mar;28(3):600. doi: 10.1038/s41591-022-01693-7.
Zur Publikation.

Koo CZ, Matthews AL, Harrison N, Szyroka J, Nieswandt B, Gardiner EE, Poulter NS, Tomlinson MG. (2022)
The Platelet Collagen Receptor GPVI Is Cleaved by Tspan15/ADAM10 and Tspan33/ADAM10 Molecular Scissors.
Int J Mol Sci. 2022 Feb 23;23(5):2440. doi: 10.3390/ijms23052440.
Zur Publikation.

Stegner D, Göb V, Krenzlin V, Beck S, Hemmen K, Schuhmann MK, Schörg BF, Hackenbroch C, May F, Burkard P, Pinnecker J, Zernecke A, Rosenberger P, Greinacher A, Pichler BJ, Heinze KG, Stoll G, Nieswandt B. (2022)
Foudroyant cerebral venous (sinus) thrombosis triggered through CLEC-2 and GPIIb/IIIa dependent platelet activation. 
Nature Cardiovascular Research (10.02.2022) doi: 10.1038/s44161-021-00017-1.

Sachs L, Wesche J, Lenkeit L, Greinacher A, Bender M, Otto O, Palankar R. (2022) 
Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping.
Commun Biol. 2022 Jan 21;5(1):86. doi: 10.1038/s42003-021-02982-6.
Zur Publikation.

Bennett C, Lawrence M, Guerrero JA, Stritt S, Waller AK, Yan Y, Mifsud RW, Ballester-Beltran J, Baig AA, Mueller A, Mayer L, Warland J, Penkett CJ, Akbari P, Moreau T, Evans AL, Mookerjee S, Hoffman GJ, Saeb-Parsy K, Adams D, Couzens AL, Bender M, Erber W, Nieswandt B, Read RJ, Ghevaert C. (2022)
CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythaemia.
Blood. 2022 Apr 7;139(14):2227-2239. doi: 10.1182/blood.2021013113.
Zur Publikation.

Rosa A, Butt E, Hopper CP, Loroch S, Bender M, Schulze H, Sickmann A, Vorlova S, Seizer P, Heinzmann D, Zernecke A. (2022)
Cyclophilin A Is Not Acetylated at Lysine-82 and Lysine-125 in Resting and Stimulated Platelets.
Int J Mol Sciences 2022 Jan 27;23(3):1469. doi: 10.3390/ijms23031469.
Zur Publikation.

Schanbacher C, Bieber M, Reinders Y, Cherpokova D, Teichert C, Nieswandt B, Sickmann A, Kleinschnitz C, Langhauser F, Lorenz K. (2022)
ERK1/2 Activity Is Critical for the Outcome of Ischemic Stroke.
Int J Mol Sci. 2022 Jan 9 ;23(2):706. doi: 10.3390/ijms23020706.
Zur Publikation. 

Perrella G, Montague SJ, Brown HC, Garcia Quintanilla L, Slater A, Stegner D, Thomas M, Heemskerk JWM, Watson SP. (2022)
Role of Tyrosine Kinase Syk in Thrombus Stabilisation at High Shear.
Int J Mol Sci. 2022 Jan 1;23(1):493. doi: 10.3390/ijms23010493.
Zur Publikation.

Navarro S, Stegner D, Nieswandt B, Heemskerk JWM, Kuijpers MJE. (2021/2022)
Temporal Roles of Platelet and Coagulation Pathways in Collagen- and Tissue Factor-Induced Thrombus Formation.
Int J Mol Sci. 2022 Jan; Indexed: 2022-03 07. Articlr No:358. doi: 10.3390/ijms23010358.
Zur Publikation (lt Web of Sci.)
Int J Mol Sci. 2021 Dec 29;23(1):358. doi: 10.3390/ijms23010358.
Zur Publikation (lt PubMed). 

Cullmann K, Jahn M, Spindler M, Schenk F, Manukjan G, Mucci A, Steinemann D, Boller K, Schulze H, Bender M, Moritz T, Modlich U. (2021) 
Forming megakaryocytes from murine-induced pluripotent stem cells by the inducible overexpression of supporting factors.
Res Pract Thromb Haemost. 2021 Jan (lt. Web of Sci.) 2020 Dec 3 (lt. PubMed);5(1):111-124. doi: 10.1002/rth2.12453. eCollection 2021 Jan.
Zur Publikation.

Göb V, Voll MG, Zimmermann L, Hemmen K, Stoll G, Nieswandt B, Schuhmann MK, Heinze KG, Stegner D. (2021)
Infarct growth precedes cerebral thrombosis following experimental stroke in mice.
Sci Rep. 2021 Nov 24;11(1):22887. doi: 10.1038/s41598-021-02360-6.
Zur Publikation.

Italiano JE, Bender M, Merrill-Skoloff G, Ghevaert C, Nieswandt B, Flaumenhaft R. (2021)
Microvesicles, but not platelets, bud off from mouse bone marrow megakaryocytes.  
Blood. 2021 Nov 18;138(20):1998-2001. doi: 10.1182/blood.2021012496.
Zur Publikation.

Beck S, Stegner D, Loroch S, Baig AA, Göb V, Schumbrutzki C, Eilers E, Sickmann A, May F, Nolte MW, Panousis C, Nieswandt B. (2021)
Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.
J Thromb Haemost. 2021 Nov;19(11):2835-2840. doi: 10.1111/jth.15488. Epub 2021 Aug 19.
Zur Publikation.

Clark JC, Neagoe RAI, Zuidscherwoude M, Kavanagh DM, Slater A, Martin EM, Soave M, Stegner D, Nieswandt B, Poulter NS, Hummert J, Herten DP, Tomlinson MG, Hill SJ, Watson SP. (2021)
Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation.
Thromb Haemost. 2021 Nov;121(11):1435-1447. doi: 10.1055/a-1401-5014. Epub 2021 Apr 14. 2021 Feb 26 Online ahead of print.
Zur Publikation.

Bieber M, Schuhmann MK, Kollikowski AM, Stegner D, Nieswandt B, Pham M, Stoll G. (2021)
Targeting platelet glycoprotein VI attenuates progressive ischemic brain damage before recanalization during middle cerebral artery occlusion in mice.
Exp Neurol. 2021 Oct; 344:113804. doi: 10.1016/j.expneurol.2021.113804. Epub 2021 Jul 6.
Zur Publikation.

Megy K, Downes K, Morel-Kopp MC, Bastida JM, Brooks S, Bury L, Leinoe E, Gomez K, Morgan NV, Othman M, Ouwehand WH, Perez Botero J, Rivera J, Schulze H, Trégouët DA, Freson K. (2021)
GoldVariants, a resource for sharing rare genetic variants detected in bleeding, thrombotic, and platelet disorders: Communication from the ISTH SSC Subcommittee on Genomics in Thrombosis and Hemostasis.
J Thromb Haemost. 2021 Oct;19(10):2612-2617. doi: 10.1111/jth.15459. Epub 2021 Aug 5.
Zur Publikation.

Vogelsang A, Eichler S, Huntemann N, Masanneck L, Böhnlein H, Schüngel L, Willison A, Loser K, Nieswandt B, Kehrel BE, Zarbock A, Göbel K, Meuth SG. (2021)
Platelet Inhibition by Low-Dose Acetylsalicylic Acid Reduces Neuroinflammation in an Animal Model of Multiple Sclerosis.
Int J Mol Sci. 2021 Sep 14;22(18):9915. doi: 10.3390/ijms22189915.
Zur Publikation.

Quach ME, Chen W, Wang Y, Deckmyn H, Lanza F, Nieswandt B, Li R. (2021)
Differential regulation of the platelet GPIb-IX complex by anti-GPIbβ antibodies.
J Thromb Haemost. 2021 Aug;19(8):2044-2055. doi: 10.1111/jth.15359. Epub 2021 May 20.
Zur Publikation.

Manke MC, Geue S, Coman C, Peng B, Kollotzek F, Münzer P, Walker B, Huber SM, Rath D, Sickmann A, Stegner D, Duerschmied D, Lang F, Nieswandt B, Gawaz M, Ahrends R, Borst O. (2021) 
ANXA7 Regulates Platelet Lipid Metabolism and Ca2+ Release in Arterial Thrombosis.
Circ Res. 2021 Aug 6;129(4):494-507. doi: 10.1161/CIRCRESAHA.121.319207. Epub 2021 Jun 28.
Zur Publikation.

Laukner A, Truchet L, Manukjan G, Schulze H, Langbein-Detsch I, Mueller E, Leeb T, Kehl A. (2021) 
Effects of Cocoa Genotypes on Coat Color, Platelets and Coagulation Parameters in French Bulldogs.
Genes (Basel). 2021 Jul 19;12(7):1092. doi: 10.3390/genes12071092.
Zur Publikation.

Heib T, Gross C, Müller ML, Stegner D, Pleines I. (2021)
Isolation of murine bone marrow by centrifugation or flushing for the analysis of hematopoietic cells - a comparative study.
Platelets. 2021 Jul 4;32(5):601-607. doi: 10.1080/09537104.2020.1797323. Epub 2020 Jul 29.
Zur Publikation.

Jadoui S, Le Chapelain O, Ollivier V, Mostefa-Kara A, Di Meglio L, Dupont S, Gros A, Nomenjanahary MS, Desilles JP, Mazighi M, Nieswandt B, Loyau S, Jandrot-Perrus M, Mangin PH, Ho-Tin-Noé B. (2021)
Glenzocimab does not impact glycoprotein VI-dependent inflammatory haemostasis. 
Haematologica. 2021 Jul 1;106(7):2000-2003. doi: 10.3324/haematol.2020.270439.
Zur Publikation. 

Weiss LJ, Manukjan G, Pflug A, Winter N, Weigel M, Nagler N, Kredel M, Lâm TT, Nieswandt B, Weismann D, Schulze H. (2021)
Acquired platelet GPVI receptor dysfunction in critically ill patients with sepsis.
Blood. 2021 Jun 3;137(22):3105-3115. doi: 10.1182/blood.2020009774.
Zur Publikation. 

Herrmann J, Notz Q, Schlesinger T, Stumpner J, Kredel M, Sitter M, Schmid B, Kranke P, Schulze H, Meybohm P, Lotz C. (2021)
Point of care diagnostic of hypercoagulability and platelet function in COVID-19 induced acute respiratory distress syndrome: a retrospective observational study.
Thromb J. 2021 Jun 2;19(1):39. doi: 10.1186/s12959-021-00293-8.
Zur Publikation. 

Chen C, Rawat D, Samikannu B, Bender M, Preissner KT, Linn T. (2021)
Platelet glycoprotein VI-dependent thrombus stabilization is essential for the intraportal engraftment of pancreatic islets.
Am J Transplant. 2021 Jun;21(6):2079-2089. doi: 10.1111/ajt.16375. Epub 2020 Nov 19.
Zur Publikation.

Stahnke S, Döring H, Kusch C, de Gorter DJJ, Dütting S, Guledani A, Pleines I, Schnoor M, Sixt M, Geffers R, Rohde M, Müsken M, Kage F, Steffen A, Faix J, Nieswandt B, Rottner K, Stradal TEB. (2021)
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion.
Curr Biol. 2021 May 24;31(10):2051-2064.e8. doi: 10.1016/j.cub.2021.02.043. Epub 2021 Mar 11.
Zur Publikation. 

Heib T, Hermanns HM, Manukjan G, Englert M, Kusch C, Becker IC, Gerber A, Wackerbarth LM, Burkard P, Dandekar T, Balkenhol J, Jahn D, Beck S, Meub M, Dütting S, Stigloher C, Sauer M, Cherpokova D, Schulze H, Brakebusch C, Nieswandt B, Nagy Z, Pleines I. (2021)
RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.
Cell Rep. 2021 May 11;35(6):109102. doi: 10.1016/j.celrep.2021.109102.
Zur Publikation.

Bornert A, Boscher J, Pertuy F, Eckly A, Stegner D, Strassel C, Gachet C, Lanza F, Léon C. (2021)
Cytoskeletal-based mechanisms differently regulate in vivo and in vitro proplatelet formation.
Haematologica. 2021 May 1;106(5):1368-1380. doi: 10.3324/haematol.2019.239111.
Zur Publikation.

Haining EJ, Lowe KL, Wichaiyo S, Kataru RP, Nagy Z, Kavanagh DP, Lax S, Di Y, Nieswandt B, Ho-Tin-Noé B, Mehrara BJ, Senis YA, Rayes J, Watson SP. (2021)
Lymphatic blood filling in CLEC-2-deficient mouse models. 
Platelets. 2021 Apr 3;32(3):352-367. doi: 10.1080/09537104.2020.1734784. Epub 2020 Mar 4.
Zur Publikation.

Janus-Bell E, Ahmed MU, Receveur N, Mouriaux C, Nieswandt B, Gardiner EE, Gachet C, Jandrot-Perrus M, Mangin PH. (2021)
Differential Role of Glycoprotein VI in Mouse and Human Thrombus Progression and Stability. 
Thromb Haemost. 2021 Apr;121(4):543-546. doi: 10.1055/s-0040-1718737. Epub 2020 Oct 29.
Zur Publikation. No abstract available. 

Wagner N, Mott K, Upcin B, Stegner D, Schulze H, Ergün S. (2021)
CXCL12-Abundant Reticular (CAR) Cells Direct Megakaryocyte Protrusions across the Bone Marrow Sinusoid Wall. 
Cells. 2021 Mar 24;10(4):722. doi: 10.3390/cells10040722.
Zur Publikation.

Stegner D, Nieswandt B. (2021)
XPoRting (poly)phosphates limits thrombosis.
Blood. 2021 Mar 11;137(10):1278-1280. doi: 10.1182/blood.2020008973.
Zur Publikation. 

Althaus K, Marini I, Zlamal J, Pelzl L, Singh A, Häberle H, Mehrländer M, Hammer S, Schulze H, Bitzer M, Malek N, Rath D, Bösmüller H, Nieswandt B, Gawaz M, Bakchoul T, Rosenberger P. (2021) 
Antibody-induced procoagulant platelets in severe COVID-19 infection.
Blood. 2021 Feb 25;137(8):1061-1071. doi: 10.1182/blood.2020008762.
Zur Publikation. 

Bender M, Palankar R. (2021)
Platelet Shape Changes during Thrombus Formation: Role of Actin-Based Protrusions. 
Hamostaseologie. 2021 Feb;41(1):14-21. doi: 10.1055/a-1325-0993. Epub 2021 Feb 15.
Zur Publikation.

Gadi I, Fatima S, Elwakiel A, Nazir S, Mohanad Al-Dabet M, Rana R, Bock F, Manoharan J, Gupta D, Biemann R, Nieswandt B, Braun-Dullaeus R, Besler C, Scholz M, Geffers R, Griffin JH, Esmon CT, Kohli S, Isermann B, Shahzad K. (2021)
Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently. 
Circ Res. 2021 Feb 19;128(4):513-529. doi: 10.1161/ CIRCRESAHA.120.317219. Epub 2020 Dec 23.
Zur Publikation.

Schuhmann MK, Bieber M, Franke M, Kollikowski AM, Stegner D, Heinze KG, Nieswandt B, Pham M, Stoll G. (2021)
Platelets and lymphocytes drive progressive penumbral tissue loss during middle cerebral artery occlusion in mice.
J Neuroinflammation. 2021 Feb 18;18(1):46. doi: 10.1186/s12974-021-02095-1.
Zur Publikation.

Rommel MGE, Milde C, Eberle R, Schulze H, Modlich U. (2020)
Endothelial-platelet interactions in influenza-induced pneumonia: A potential therapeutic target.
Anat Histol Embryol 2020; 49(5): 606-619; 

Kollikowski A, Pham M, Nieswandt B, Mullges W, Stoll G, Schuhmann M. (2020)
Local Platelet Activation in the Ischemic Vascular Compartment during Hyperacute human Stroke.
International Journal of Stroke Volume 15 Issue 1_SUPPL Page 227-227 Supplement 1_ Special Issue SI 
Meeting Abstract 00841 Published Nov 2020 Indexed 2021-01-19

Stoll G, Bieber M, Franke M, Kollikowski A, Nieswandt B, Pham M, Schuhmann M. (2020) 
Platelets and Immune Cells drive Stroke Progression into the Penumbra in Mice.
International Journal of Stroke Volume 15 Issue 1_SUPPL Page 24-24 Supplement 1_ Special Issue SI
Meeting Abstract 00096 Published Nov 2020 Indexed 2021-01-19.

Bieber M, Schuhmann M, Nieswandt B, Pham M, Stoll G. (2020)
Targeting Platelet GPVI reduces primary Infarct Growth during MCA Occlusion in Mice.
Int J Stroke 2020; 15 Suppl 1_(1_SUPPL): 615-615; Impact Factor=5.266; Impact Factor 2021=6.948;
Meeting Abstract

Balkenhol J, Kaltdorf KV, Mammadova-Bach E, Braun A, Nieswandt B, Dittrich M, Dandekar T. (2020)
Comparison of the central human and mouse platelet signaling cascade by systems biological analysis. 
BMC Genomics. 2020 Dec 22;21(1):897. doi: 10.1186/s12864-020-07215-4. Published: Dec 22 2020. Indexed: 2021-01-07.
Zur Publikation.

Pfeil EM, Brands J, Merten N, Vögtle T, Vescovo M, Rick U, Albrecht IM, Heycke N, Kawakami K, Ono Y, Ngako Kadji FM, Hiratsuka S, Aoki J, Häberlein F, Matthey M, Garg J, Hennen S, Jobin ML, Seier K, Calebiro D, Pfeifer A, Heinemann A, Wenzel D, König GM, Nieswandt B, Fleischmann BK, Inoue A, Simon K, Kostenis E. (2020)
Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs. 
Mol Cell. 2020 Dec 17;80(6):940-954.e6. doi: 10.1016/j.molcel.2020.10.027. Epub 2020 Nov 16.
Zur Publikation.

Nicolai L, Schiefelbein K, Lipsky S, Leunig A, Hoffknecht M, Pekayvaz K, Raude B, Marx C, Ehrlich A, Pircher J, Zhang Z, Saleh I, Marel AK, Löf A, Petzold T, Lorenz M, Stark K, Pick R, Rosenberger G, Weckbach L, Uhl B, Xia S, Reichel CA, Walzog B, Schulz C, Zheden V, Bender M, Li R, Massberg S, Gaertner F. (2020)
Vascular surveillance by haptotactic blood platelets in inflammation and infection. 
Nat Commun. 2020 Nov 13;11(1):5778. doi: 10.1038/s41467-020-19515-0.
Zur Publikation.

Volz J, Kusch C, Beck S, Popp M, Vögtle T, Meub M, Scheller I, Heil HS, Preu J, Schuhmann MK, Hemmen K, Premsler T, Sickmann A, Heinze KG, Stegner D, Stoll G, Braun A, Sauer M, Nieswandt B. (2020)
BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation. 
J Clin Invest. 2020 Nov 2;130(11):6064-6079. doi: 10.1172/JCI136457.
Zur Publikation.

Gupta S, Konradt C, Corken A, Ware J, Nieswandt B, Di Paola J, Yu M, Wang D, Nieman MT, Whiteheart SW, Brass LF. (2020)
Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation. 
Proceedings of the National Academy of Sciences of the United States of America (Proc Natl Acad Sci U S A). 2020 Sep 29;117(39):24316-24325. doi: 10.1073/pnas.2007642117. Epub 2020 Sep 14.
Zur Publikation.

Schuhmann MK, Stoll G, Bieber M, Vögtle T, Hofmann S, Klaus V, Kraft P, Seyhan M, Kollikowski AM, Papp L, Heuschmann PU, Pham M, Nieswandt B, Stegner D. (2020)
CD84 Links T Cell and Platelet Activity in Cerebral Thrombo-Inflammation in Acute Stroke. 
Circ Res. 2020 Sep 25;127(8):1023-1035. doi: 10.1161/CIRCRESAHA.120.316655. Epub 2020 Jul 30.
Zur Publikation.

Schmitt MER, Lutz J, Haase P, Bösl MR, Wienands J, Engels N, Voehringer D. (2020)
The B-cell antigen receptor of IgE-switched plasma cells regulates memory IgE responses. 
J Allergy Clin Immunol. 2020 Sep;146(3):642-651.e5. doi: 10.1016/j.jaci.2020.02.015. Epub 2020 Feb 28.
Zur Publikation.

Vögtle T, Baig AA, Volz J, Duchow TB, Pleines I, Dütting S, Nitschke L, Watson SP, Nieswandt B. (2020)
Critical redundant functions of the adapters Grb2 and Gads in platelet (hem)ITAM signaling in mice  Platelets.
2020 Aug 17;31(6):801-811. doi: 10.1080/09537104.2019.1709633. Epub 2020 Jan 16.
Zur Publikation.

Bächer C, Bender M, Gekle S. (2020)
Flow-accelerated platelet biogenesis is due to an elasto-hydrodynamic instability. 
Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):18969-18976. doi: 10.1073/pnas.2002985117. Epub 2020 Jul 27.
Zur Publikation. 

Ariens R, Becattini C, Bender M, Bergmeier W, Castoldi E, Devreese K, Ellis M, Gailani D, Ignjatovic V, James PD, Kerrigan S, Lambert M, Lee LH, Levi M, Maugeri N, Meijers J, Melero-Martin J, Michelson AD, Mingozzi F, Neeves K, Ni H, Olsson AK, Prohászka Z, Ranson M, Riva N, Senis Y, van Ommen CH, Vaughan DE, Weisel J. (2020)
Illustrated State-of-the-Art Capsules of the ISTH 2020 Congress. 
Res Pract Thromb Haemost. 2020 Jul 12;4(5):680-713. doi: 10.1002/rth2.12368. eCollection 2020 Jul.
Zur Publikation. REVIEW

Stegner D, Heinze KG. (2020)
Intravital imaging of megakaryocytes. 
Platelets. 2020 Jul 3;31(5):599-609. doi: 10.1080/09537104.2020.1738366. Epub 2020 Mar 10.
Zur Publikation.

Bertović I, Kurelić R, Milošević I, Bender M, Krauss M, Haucke V, Jurak Begonja A. (2020)
Vps34 derived phosphatidylinositol 3-monophosphate modulates megakaryocyte maturation and proplatelet production through late endosomes/lysosomes. 
J Thromb Haemost. 2020 Jul;18(7):1756-1772. doi: 10.1111/jth.14764. Epub 2020 Mar 17.
Zur Publikation.

Scheller I, Stritt S, Beck S, Peng B, Pleines I, Heinze KG, Braun A, Otto O, Ahrends R, Sickmann A, Bender M, Nieswandt B. (2020)
Coactosin-like 1 integrates signaling critical for shear-dependent thrombus formation in mouse platelets. 
Haematologica. 2020 Jun;105(6):1667-1676. doi: 10.3324/haematol.2019.225516. Epub 2019 Oct 3.
Zur Publikation.

Salzmann M, Schrottmaier WC, Kral-Pointner JB, Mussbacher M, Volz J, Hoesel B, Moser B, Bleichert S, Morava S, Nieswandt B, Schmid JA, Assinger A. (2020)
Genetic platelet depletion is superior in platelet transfusion compared to current models. 
Haematologica. 2020 Jun;105(6):1738-1749. doi: 10.3324/haematol.2019.222448. Epub 2019 Sep 19.
Zur Publikation.

Salzmann M, Schrottmaier WC, Kral-Pointner JB, Mussbacher M, Volz J, Hoesel B, Moser B, Bleichert S, Morava S, Nieswandt B, Schmid JA, Assinger A. (2020)
Korrektur (Fig. 5): Genetic platelet depletion is superior in platelet transfusion compared to current models. 
Haematologica. 2020 Nov 1;105(11):2698. doi: 10.3324/haematol.2020.266072.
Zur Publikation. 

Burkard P, Vogtle T, Nieswandt B. (2020) 
Platelets in Thrombo-Inflammation: Concepts, Mechanisms, and Therapeutic Strategies for Ischemic Stroke. 
Hamostaseologie. 2020 Jun;40(2):153-164. doi: 10.1055/a-1151-9519. Epub 2020 May 26. 
Zur Publikation.

Becker IC, Scheller I, Wackerbarth LM, Beck S, Heib T, Aurbach K, Manukjan G, Gross C, Spindler M, Nagy Z, Witke W, Lappalainen P, Bender M, Schulze H, Pleines I, Nieswandt B. (2020)
Actin/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1.
Blood Adv. 2020 May 26;4(10):2124-2134. doi: 10.1182/bloodadvances.2019001303.
Zur Publikation. 

Stoll G, Bieber M, Franke M. et al. (2020)
Thrombo-inflammation is a driving force of stroke progression into the penumbra in mice.
European Journal of Neurology. Volume: 27, Supplement:1, Pages: 419- 441. Meeting Abstract: EPR3009, Published: ‏ MAY 2020. 

Mammadova-Bach E, Gil-Pulido J, Sarukhanyan E, Burkard P, Shityakov S, Schonhart C, Stegner D, Remer K, Nurden P, Nurden AT, Dandekar T, Nehez L, Dank M, Braun A, Mezzano D, Abrams SI, Nieswandt B. (2020)
Platelet glycoprotein VI promotes metastasis through interaction with cancer cell-derived galectin-3: 
Blood. 2020 Apr 2;135(14):1146-1160. doi: 10.1182/blood.2019002649.
Zur Publikation.

Green HLH, Zuidscherwoude M, Alenazy F, Smith CW, Bender M, Thomas SG. (2020)
SMIFH2 inhibition of platelets demonstrates a critical role for formin proteins in platelet cytoskeletal dynamics. 
J Thromb Haemost. 2020 Apr;18(4):955-967. doi: 10.1111/jth.14735. Epub 2020 Feb 17.
Zur Publikation.

Gorelashvili MG, Angay O, Hemmen K, Klaus V, Stegner D, Heinze KG. (2020)
Megakaryocyte volume modulates bone marrow niche properties and cell migration dynamics. 
Haematologica. 2020 Apr;105(4):895-904. doi: 10.3324/haematol.2018.202010. Epub 2019 Jun 27.
Zur Publikation.

Köhler D, Granja T, Volz J, Koeppen M, Langer HF, Hansmann G, Legchenko E, Geisler T, Bakchoul T, Eggstein C, Häberle HA, Nieswandt B, Rosenberger P. (2020)
Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb. 
Nat Commun. 2020 Mar 11;11(1):1315. doi: 10.1038/s41467-020-14958-x.
Zur Publikation. 

Scheller I, Nieswandt B. (2020)
Novel Approaches to Unravel Risk Factors and Mechanisms of Venous Thrombosis. 
Thromb Haemost. 2020 Mar;120(3):372. doi: 10.1055/s-0040-1702232. Epub 2020 Mar 5.
Zur Publikation.

Kollikowski AM, Schuhmann MK, Nieswandt B, Müllges W, Stoll G, Pham M. (2020)
Local Leukocyte Invasion during Hyperacute Human Ischemic Stroke. 
Ann Neurol. 2020 Mar;87(3):466-479. doi: 10.1002/ana.25665. Epub 2020 Jan 16.
Zur Publikation.

Manukjan G, Wiegering VA, Reindl T, Strauß G, Klopocki E, Schulze H, Andres O. (2020)
Novel variants in FERMT3 and RASGRP2-Genetic linkage in Glanzmann-like bleeding disorders. 
Pediatr Blood Cancer. 2020 Feb;67(2):e28078. doi: 10.1002/pbc.28078. 
Epub 2019 Nov 14.
Zur Publikation. 

Dunster JL, Unsworth AJ, Bye AP, Haining EJ, Sowa MA, Di Y, Sage T, Pallini C, Pike JA, Hardy AT, Nieswandt B, Garcia A, Watson SP, Poulter NS, Gibbins JM, Pollitt AY. (2020)
Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation. 
Journal of Thrombosis and Haemostasis. Volume: 18, Issue:2, Pages: 485-496, Published: FEB 2020 - Early Access: DEC 2019. 

Schurr Y, Sperr A, Volz J, Beck S, Reil L, Kusch C, Eiring P, Bryson S, Sauer M, Nieswandt B, Machesky L, Bender M. (2019)
Platelet lamellipodium formation is not required for thrombus formation and stability. 
Blood Volume: 134, Issue: ‏25, Pages: 2318-2329, Published:‏ DEC 19 2019.

Geue S, Aurbach K, Manke M-C, Manukjan G, Münzer P, Stegner D, Brähler C, Walker-Allgaier B, Märklin M, Borst CE, Quintanilla-Fend L, Rath D, Geisler T, Salih H R, Seizer P, Lang F, Nieswandt B, Gawaz M, Schulze H, Pleines I, Borst O. (2019)
Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis.
Blood Volume: ‏134, Issue: 21, Pages: 1847-1858, Published: NOV 21 2019.

Stegner D, Klaus V, Nieswandt B. (2019) 
Platelets as Modulators of Cerebral Ischemia/Reperfusion Injury 
Frontiers in Immunology: Volume: 10, Article Number: 2505 Published:‏ NOV 1 2019.

Stegner D, Hofmann S, Schuhmann M, Kraft P, Herrmann AM, Popp S, Hoehn M, Popp M, Klaus V, Post A, Kleinschnitz C, Braun A, Meuth S, Lesch K-P, Stoll G, Kraft R, Nieswandt B. (2019)
Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke. 
Stroke Volume: 50, Issue: 11, Pages: 3238-3245, Published: NOV 2019.

Manukjan G, Eilenberger J, Andres O, Schambeck C, Eber S, Schulze H. (2019)
Functional Classification of Paediatric Patients with Non-syndromic Delta-Storage Pool Deficiency. 
Hamostaseologie. 2019 Nov;39(4):383-391. doi: 10.1055/s-0038-1675574. 
Epub 2018 Nov 21.
Zur Publikation. 

Eyrich M, Schulze H. (2019)
HLA Matching in Pediatric Stem Cell Transplantation. 
Transfus med Hemother. 2019, 46:348-354. doi:10.1159/000502422
Zur Publikation.

Vögtle T, Sharma S, Mori J, Nagy Z, Semeniak D, Scandola C, Geer MJ, Smith CW, Lane J, Pollack S, Lassila R, Jouppila A, Barr AJ, Ogg DJ, Howard TD, McMiken HJ, Warwicker J, Geh C, Rowlinson R, Abbott WM, Eckly A, Schulze H, Wright GJ, Mazharian A, Fütterer K, Rajesh S, Douglas MR, Senis YA. (2019)
Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B.
Elife. Volume: ‏8, Article Number: e46840, Published:  AUG 22 2019. 

Semeniak D, Faber K, Öftering P, Manukjan G, Schulze H. (2019)
Impact of Itga2-Gp6-double collagen receptor deficient mice for bone marrow megakaryocytes and platelets.  
Plos One. 2019 Aug 9;14(8):e0216839. doi: 10.1371/journal.pone.0216839. eCollection 2019. 
Zur Publikation. Free PMC article. 

Noy PJ, Gavin RL, Colombo D, Haining EJ, Reyat J S, Payne H, Thielmann I, Lokman A B, Neag G, Yang J, Lloyd T, Harrison N, Heath V, Gardiner C, Whitworth K M, Robinson J, Koo C Z, Di Maio A, Harrison P, Lee S P, Michelangeli F, Kalia N, Rainger G E, Nieswandt B, Brill A, Watson SP, Tomlinson MG. (2019)
Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells. 
Haematologica. Volume: ‏  104Issue:9, Pages: 1982-1905, Published: AUG 31 2019.

Herster F, Bittner Z, Codrea, M C, Archer N, Heister M, Loeffler M, Heumos S, Wegner J, Businger R, Schindler M, Stegner D, Schaekel K, Grabbe S, Ghoreschi K, Miller L, Weber A. (2019)
Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis. 
Frontiers in Immunology. Volume: ‏10, Article Number:1867, Published: ‏ AUG 16 2019 

Aurbach K, Spindler M, Haining EJ, Bender M, Pleines I. (2019)
Blood collection, platelet isolation and measurement of platelet count and size in mice-a practical guide.
Platelets. 2018 Oct 22:1-10. doi: 10.1080/09537104.2018.1528345. [Epub ahead of print] 
Zur Publikation. Published Aug 2019.

Stoll G, Nieswandt B. (2019)
Thrombo-inflammation in acute ischaemic stroke - implications for treatment. 
Nature Reviews Neurology. Volume: ‏15, Issue: 8, Pages: ‏473-481, Published: AUG 2019. 

Nagy M, van Geffen J P, Stegner D, Adams D J, Braun A, de Witt SM, Elvers M, Geer M, Kuijpers MJE, Kunzelmann K, Mori J, Oury C, Pircher J, Pleines I, Poole A W, Senis Y A, Verdoold R, Weber C, Nieswandt B, Heemskerk JWM, Baaten CCFMJ. (2019)
Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis. 
Frontiers in Cardiovascular Medicine: 6, Article Number: 99, Published: JUL 30 2019. 

Heinze K G, Stegner D. (2019)
Looking into the nursery of platelets: Imaging of the bone marrow in vivo, in vitro and in silico. 
European Biophysics Journal with Biophysics Letters. Volume: 48, Supplement: ‏1, Pages: S64-S64, Meeting Abstract: ‏ O-133. Published: ‏JUL 2019. Meeting Abtract.

Volz J, Mammadova-Bach E, Gil-Pulido J, Nandigama R, Remer K, Sorokin L, Zernecke A, Abrams S I, Ergun S, Henke E, Nieswandt B. (2019)
Inhibition of platelet GPVI induces intratumor hemorrhage and increases efficacy of chemotherapy in mice. 
Blood. Volume: 133, Issue: 25, Pages: 2696-2706, Published:‏ JUN 20 2019.

Gotru SK, van Geffen JP, Nagy M, Mammadova-Bach E, Eilenberger J, Volz J, Manukjan G, Schulze H, Wagner L, Eber S, Schambeck C, Deppermann C, Brouns S, Nurden P, Greinacher A, Sachs U, Nieswandt B, Hermanns HM, Heemskerk JWM, Braun A. (2019)
Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases. 
Scientific Reports: Volume:9, Article Number: 8333, Published: JUN 6 2019. 

Schurr Y, Spindler M, Kurz H, Bender M. (2019)
The cytoskeletal crosslinking Protein MACF1 is dispensable for thrombus formation and hemostasis.
Sci Rep. 2019 May 22;9(1):7726. doi: 10.1038/s41598-019-44143-6. 

Neidler S, Kruspig B, Hewit K, Monteverde T, Gyuraszova K, Braun A, Clark W, James D, Hedley A, Nieswandt B, Shanks E, Dick C, Murphy D J. (2019)
Identification of a Clinically Relevant Signature for Early Progression in KRAS-Driven Lung Adenocarcinoma. 
Cancers. Volume:11, Issue: 5, Article Number: 600, Published: MAY 2019. 

Schuhmann MK, Kraft P, Bieber M, Kollikowski AM, Schulze H, Nieswandt B, Pham M, Stegner D, Stoll G. (2019)
Targeting Platelet GPVI Plus rt-PA Administration but Not 21-Mediated Collagen Binding Protects against Ischemic Brain Damage in Mice. 
International Journal of Molecular Sciences. Volume: 20, Issue:8, Article Number: 2019, Published: APR 2 2019. 

Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath, D, Ali A, Wolf M J, Drescher H, Healy M, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Adams D H, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers M N, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R; Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. (2019)
Platelet GPIb alpha is a mediator and potential interventional target for NASH and subsequent liver cancer. 
Nature Medicine. Volume: 25, Issue:4, Pages: ‏ 641-+, Published: APR 2019. 

Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Chauhan A, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. (2019)
2022 Mar: Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.
Nat Med. 2022 Mar;28(3):600. doi: 10.1038/s41591-022-01693-7.
Zur Publikation.

Strassel C, Magiera MM, Dupuis A, Batzenschlager M, Hovasse A, Pleines I, Gueguen P, Eckly A, Moog S, Mallo L, Kimmerlin Q, Chappaz S, Strub J-M, Kathiresan N, de la Salle H, Van Dorsselaer A, Ferec C, Py J-Y, Gachet C, Schaeffer-Reiss C, Kile BT, Janke C, Lanza F. (2019)
An essential role for alpha4A-tubulin in platelet biogenesis. 
Life science alliance. Volume:2, Issue:1, Published: ‏ 2019Feb 13 (Print 2019-02).

Bieber M, Schuhmann MK, Volz J, Kumar GJ, Vaidya JR, Nieswandt B, Pham M, Stoll G, Kleinschnitz C, Kraft P. (2019)
Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function. 
Stroke. Volume: ‏50, Issue:2, Pages: 478-486. Published: FEB 2019.

Albert-Weissenberger C, Hopp S, Nieswandt B, Siren A-L, Kleinschnitz C, Stetter C. (2019)
How is the formation of microthrombi after traumatic brain injury linked to inflammation?  
Journal of Neuroimmunology. Volume:326, Pages: 9-13, Published: JAN 15 2019. REVIEW.

Pleines I, Cherpokova D, Bender M. (2019)
Rho GTPases and their downstream effectors in megakaryocyte biology. 
Platelets. 2018 Jun 18:1-8. doi: 10.1080/09537104.2018.1478071. [Epub ahead of print] 
Zur Publikation. Published in 2019 Jan 2.

Rayes J, Watson SP, Nieswandt B (2019)
Functional significance of the platelet immune receptors GPVI and CLEC-2. 
Journal of Clinical Investigation. Volume: 129, Issue: 1, Pages: 12-23. Published: JAN 2 2019. REVIEW.

Mammadova-Bach E, Nagy M, Heemskerk JWM, Nieswandt B, Braun A. (2019).
Store-operated calcium entry in thrombosis and thrombo-inflammation. 
Cell Calcium. Volume:77, Pages: 29-48. Published:‏ JAN 2019. 

Mammadova-Bach E, Nagy M, Heemskerk JWM, Nieswandt B, Braun A. (2019)
CStore-operated calcium entry in thrombosis and thrombo-inflammation. 
Cell Calcium. 2019 Jan;77:39-48. doi: 10.1016/j.ceca.2018.11.005. Epub 2018 Nov 23.
Zur Publikation. REVIEW. 

Gekle S, Bender M. (2018)
Chapter: Red blood cell and platelet mechanics. Book: Cardiovascular mechanics (edited by Labrosse MF)
CRC Press, Taylor & Francis Group; 1st ed.     

Bender M, Otto O. (2018)
No escape-a novel tool to quantify platelet intra-thrombus movements.
Thromb Haemost. 2018 Sept 118: 1515-1516.     

Andres O, König EM, Althaus K, Bakchoul T, Bugert P, Eber S, Knöfler R, Kunstmann E, Manukjan G, Meyer O, Strauß G, Streif W, Thiele T, Wiegering V, Klopocki E, Schulze H. (2018)
Use of Targeted High-Throughput Sequencing for Genetic Classification of Patients with Bleeding Diathesis and Suspected Platelet Disorder. 
Thromkidplus Study Group of the Society of Paediatric Oncology Haematology (Gesellschaft für Pädiatrische Onkologie und Hämatologie, GPOH) and the Society of Thrombosis Haemostasis Research (Gesellschaft für Thrombose- und Hämostaseforschung, GTH). TH Open. 2018 Dec 30;2(4):e445-e454. doi: 10.1055/s-0038-1676813. eCollection 2018 Oct. 
Zur Publikation. Free PMC article. 

Noy PJ, Gavin RL, Colombo D, Haining EJ, Reyat JS, Payne H, Thielmann I, Lokman AB, Neag G, Yang J, Lloyd T, Harrison N, Heath VL, Gardiner C, Whitworth K M, Robinson J, Koo C Z, Di Maio A, Harrison P, Lee SP, Michelangeli F, Kalia N, Rainger GE, Nieswandt B, Brill A, Watson SP, Tomlinson MG. (2018)
Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells. 
Haematologica. 2018 Dec 20. pii: haematol.2018.194241. doi: 10.3324/haematol.2018.194241. [Epub ahead of print].
Zur Publikation.

Bieber M, Schuhmann MK, Volz J, Kumar GJ, Vaidya J R, Nieswandt B, Pham M, Stoll G, Kleinschnitz C, Kraft P. (2018) 
Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function. 
Stroke. 2018 Dec 18:STROKEAHA118023664. doi: 10.1161/STROKEAHA.118.023664. [Epub ahead of print].
Zur Publikation.

Welz M, Eickhoff S, Abdullah Z, Trebicka J, Gartlan K H, Spicer JA, Demetris AJ, Akhlaghi H, Anton M, Manske K, Zehn D, Nieswandt B, Kurts C, Trapani JA, Knolle P, Wohlleber D, Kastenmüller W. (2018)
Perforin inhibition protects from lethal endothelial damage during fulminant viral hepatitis. 
Nat Commun. 2018 Nov 15;9(1):4805. doi: 10.1038/s41467-018-07213-x. 
Zur Publikation.

Aurbach K, Spindler M, Haining EJ, Bender M, Pleines I. (2018) 
Blood collection, platelet isolation and measurement of platelet count and size in mice-a practical guide.
Platelets. 2018 Oct 22:1-10. doi: 10.1080/09537104.2018.1528345. [Epub ahead of print] 
Zur Publikation.

de Winde CM, Matthews AL, van Deventer S, van der Schaaf A, Tomlinson ND, Jansen E, Eble JA, Nieswandt B, McGettrick  HM, Figdor CG, Tomlinson MG, Acton SE, van Spriel AB. (2018)
C-type lectin-like receptor 2 (CLEC-2)-dependent dendritic cell migration is controlled by tetraspanin CD37. 
J Cell Sci. 2018 Oct 2;131(19). pii: jcs214551. doi: 10.1242/jcs.214551. 
Zur Publikation.

Cao H, Biondo M, Lioe H, Busfield S, Rayzman V, Nieswandt B, Bork K, Harrison L C, Auyeung P, Farkas H, Csuka D, Pelzing M, Dower S, Wilson MJ, Nash A, Nolte MW, Panousis C. (2018)
Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation. 
J Allergy Clin Immunol. 2018 Oct;142(4):1355-1358. doi: 10.1016/j.jaci.2018.06.014. Epub 2018 Jun 21. No abstract available. 
Zur Publikation.

Schuhmann MK, Kraft P, Bieber M, Haarmann A, Homola GA, Pham M, Nieswandt B, Stoll G. (2018) 
Influence of Thrombolysis on the Safety and Efficacy of Blocking Platelet Adhesion or Secretory Activity in Acute Ischemic Stroke in Mice. 
Transl Stroke Res. 2018 Oct;9(5):493-498. doi: 10.1007/s12975-017-0606-7. Epub 2018 Jan 10. 
Zur Publikation.

Mekala SR, Wörsdörfer P, Bauer J, Stoll O, Wagner N, Reeh L, Loew K, Eckner G, Kwok C K, Wischmeyer E, Dickinson ME, Schulze H, Stegner D, Benndorf R A, Edenhofer F, Pfeiffer V, Kuerten S, Frantz S, Ergün S. (2018)
Generation of Cardiomyocytes From Vascular Adventitia-Resident Stem Cells. 
Circ Res. 2018 Aug 31;123(6):686-699. doi: 10.1161/CIRCRESAHA.117.312526.
Zur Publikation.

Spindler M, van Eeuwijk JMM, Schurr Y, Nurden P, Nieswandt B, Stegner D, Reinhold A, Bender M. (2018) 
ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia.
Blood. 2018 Aug 9;132(6):635-646. doi: 10.1182/blood-2018-01-829259. Epub 2018 Jun 27. 
Zur Publikation.

Pleines I, Lebois M, Gangatirkar P, Au AE, Lane RM, Henley KJ, Kauppi M, Corbin J, Cannon P, Bernardini J, Alwis I, Jarman KE, Ellis S, Metcalf D, Jackson  P, Schoenwaelder SM, Kile BT, Josefsson EC. (2018)
Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion. 
Blood. 2018 Jul 12;132(2):197-209. doi: 10.1182/blood-2017-11-816355. Epub 2018 May 21. 
Zur Publikation.

Schulze H, Stegner D. (2018)
Imaging platelet biogenesis in vivo.
Res Pract Thromb Haemost. 2018 Jun 10;2(3):461-468. doi: 10.1002/rth2.12112. eCollection 2018 Jul. 
Zur Publikation. REVIEW.

Andres O, Henning K, Strauß G, Pflug A, Manukjan G, Schulze H. (2018)
Diagnosis of platelet function disorders: A standardized, rational, and modular flow cytometric approach. 
Platelets. 2018 Jun;29(4):347-356. doi: 10.1080/09537104.2017.1386297. Epub 2017 Dec 11. 
Zur Publikation.

Pleines I, Cherpokova D, Bender M. (2018)
Rho GTPases and their downstream effectors in megakaryocyte biology. 
Platelets. 2018 Jun 18:1-8. doi: 10.1080/09537104.2018.1478071. [Epub ahead of print] 
Zur Publikation. Published in 2019 Jan 2 (s.u. 2019).

Giles JA, Greenhalgh AD, Denes A, Nieswandt B, Coutts G, McColl BW, Allan SM. (2018) 
Neutrophil infiltration to the brain is platelet-dependent, and is reversed by blockade of platelet GPIbα.
Immunology. 2018 Jun;154(2):322-328. doi: 10.1111/imm.12892. Epub 2018 Feb 8. 
Zur Publikation.

Rayes J, Jadoui S, Lax S, Gros A, Wichaiyo S, Ollivier V, Denis CV, Ware J, Nieswandt B, Jandrot-Perrus M, Watson SP, Ho-Tin-Noé B. (2018)
The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent. 
Haematologica. 2018 Jun;103(6):e256-e258. doi: 10.3324/haematol.2017.182162. Epub 2018 Feb 1. No abstract available. 
Zur Publikation.

Stritt S, Birkholz I, Beck S, Sorrentino S, Sapra KT, Viaud J, Heck J, Gaits-Iacovoni F, Schulze H, Du X, Hartwig JH, Braun A, Bender M, Medalia O, Nieswandt B. (2018)
Profilin 1-mediated cytoskeletal rearrangements regulate integrin function in mouse platelets. 
Blood Adv. 2018 May 8;2(9):1040-1045. doi: 10.1182/bloodadvances.2017014001. No abstract available. 
Zur Publikation.

Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C. (2018)
Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. 
Nat Commun. 2018 Apr 18;9(1):1523. doi: 10.1038/s41467-018-03925-2. 
Zur Publikation.

Gotru SK, Gil-Pulido J, Beyersdorf N, Diefenbach A, Becker I C, Vögtle T, Remer K, Chubanov V, Gudermann T, Hermanns HM, Nieswandt B, Kerkau T, Zernecke A, Braun A. (2018)
Cutting Edge: Imbalanced Cation Homeostasis in MAGT1-Deficient B Cells Dysregulates B Cell Development and Signaling in Mice.
J Immunol. 2018 Apr 15;200(8):2529-2534. doi: 10.4049/jimmunol.1701467. Epub 2018 Mar 26. 
Zur Publikation.

Gupta S, Cherpokova D, Spindler M, Morowski M, Bender M, Nieswandt B.
GPVI signaling is compromised in newly formed platelets after acute thrombocytopenia in mice. 
Blood. 2018 Mar 8;131(10):1106-1110. doi: 10.1182/blood-2017-08-800136. Epub 2018 Jan 2. 
Zur Publikation. 

Claushuis TAM, de Vos AF, Nieswandt B, Boon L, Roelofs JJTH, de Boer OJ, van 't Veer C, van der Poll T. (2018) 
Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria. 
Blood. 2018 Feb 22;131(8):864-876. doi: 10.1182/blood-2017-06-788067. Epub 2017 Nov 29. 
Zur Publikation.

Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina M T, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan W I, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E. (2018) 
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration. 
Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1550-E1559. doi: 10.1073/pnas.1720553115. Epub 2018 Jan 31. 
Zur Publikation.

Gotru SK, Chen W, Kraft P, Becker IC, Wolf K, Stritt S, Zierler S, Hermanns HM, Rao D, Perraud A L, Schmitz C, Zahedi RP, Noy PJ, Tomlinson MG, Dandekar T, Matsushita M, Chubanov V, Gudermann T, Stoll G, Nieswandt B, Braun A. (2018)
TRPM7 Kinase Controls Calcium Responses in Arterial Thrombosis and Stroke in Mice. 
Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):344-352. doi: 10.1161/ATVBAHA.117.310391. Epub 2017 Nov 16. 
Zur Publikation.

Claushuis TAM, de Vos AF, Nieswandt B, Boon L, Roelofs JJTH, de Boer OJ, van 't Veer C, van der Poll T. (2018)
Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria.
Blood. 2018 Feb 22;131(8):864-876. doi: 10.1182/blood-2017-06-788067. Epub 2017 Nov 29. 
Zur Publikation.

Gorelashvili MG, Heinze KG, Stegner D. (2018)
Optical Clearing of Murine Bones to Study Megakaryocytes in Intact Bone Marrow Using Light-Sheet Fluorescence Microscopy. 
Methods Mol Biol. 2018;1812:233-253. doi: 10.1007/978-1-4939-8585-2_14. 
Zur Publikation. Buch.

Claushuis TAM, de Vos AF, Nieswandt B, Boon L, Roelofs JJTH, de Boer OJ, van 't Veer C, van der Poll T. (2017)
Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria.
Blood. 2018 Feb 22;131(8):864-876. doi: 10.1182/blood-2017-06-788067. Epub 2017 Nov 29. 
Zur Publikation.

Gotru SK, Chen W, Kraft P, Becker IC, Wolf K, Stritt S, Zierler S, Hermanns HM, Rao D, Perraud AL, Schmitz C, Zahedi RP, Noy PJ, Tomlinson MG, Dandekar T, Matsushita M, Chubanov V, Gudermann T, Stoll G, Nieswandt B, Braun A. (2017)
TRPM7 Kinase Controls Calcium Responses in Arterial Thrombosis and Stroke in Mice. 
Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):344-352. doi: 10.1161/ATVBAHA.117.310391. 
Zur Publikation.

Münzer P, Walker-Allgaier B, Geue S, Langhauser F, Geuss E, Stegner D, Aurbach K, Semeniak D, Chatterjee M, Gonzalez Menendez I, Märklin M, Quintanilla-Martinez L, Salih HR, Litchfield DW, Buchou T, Kleinschnitz C, Lang F, Nieswandt B, Pleines I, Schulze H, Gawaz M, Borst O. (2017)
CK2β regulates thrombopoiesis and Ca2+-triggered platelet activation in arterial thrombosis. 
Blood. 2017 Dec 21;130(25):2774-2785. doi: 10.1182/blood-2017-05-784413. Epub 2017 Sep 19. 
Zur Publikation.

Haining EJ, Cherpokova D, Wolf K, Becker IC, Beck S, Eble JA, Stegner D, Watson SP, Nieswandt B. (2017) 
CLEC-2 contributes to hemostasis independently of classical hemITAM signaling in mice. 
Blood. 2017 Nov 16;130(20):2224-2228. doi: 10.1182/blood-2017-03-771907. Epub 2017 Aug 23. 
Zur Publikation.

Drube S, Grimlowski R, Deppermann C, Fröbel J, Kraft F, Andreas N, Stegner D, Dudeck J, Weber F, Rödiger M, Göpfert C, Drube J, Reich D, Nieswandt B, Dudeck A, Kamradt T. (2017)
The Neurobeachin-like 2 Protein Regulates Mast Cell Homeostasis.
J Immunol. 2017 Oct 15;199(8):2948-2957. doi: 10.4049/jimmunol.1700556. Epub 2017 Sep 8. 
Zur Publikation.

Stritt S, Beck S, Becker IC, Vögtle T, Hakala M, Heinze KG, Du X, Bender M, Braun A, Lappalainen P, Nieswandt B. (2017)
Twinfilin 2a regulates platelet reactivity and turnover in mice. 
Blood. 2017 Oct 12;130(15):1746-1756. doi: 10.1182/blood-2017-02-770768. Epub 2017 Jul 25. 
Zur Publikation.

Beck S, Leitges M, Stegner D. (2017)
Protein kinase Cι/λ is dispensable for platelet function in thrombosis and hemostasis in mice.
Cell Signal. 2017 Oct;38:223-229. doi: 10.1016/j.cellsig.2017.07.015. Epub 2017 Jul 21.
Zur Publikation.

Stegner D, vanEeuwijk JMM, Angay O, Gorelashvili MG, Semeniak D, Pinnecker J, Schmithausen P, Meyer I, Friedrich M, Dütting S, Brede C, Beilhack A, Schulze H, Nieswandt B, Heinze KG. (2017)
Thrombopoiesis is spatially regulated by the bone marrow vasculature. 
Nat Commun. 2017 Jul 25;8(1):127. doi: 10.1038/s41467-017-00201-7. 
Zur Publikation.

Jamasbi J, Ayabe K, Goto S, Nieswandt B, Peter K, Siess W. (2017)
Platelet receptors as therapeutic targets: Past, present and future. 
Thromb Haemost. 2017 Jun 28;117(7):1249-1257. doi: 10.1160/TH16-12-0911. Epub 2017 Jun 9. 
Zur Publikation. REVIEW.

Dütting S, Gaits-Iacovoni F, Stegner D, Popp M, Antkowiak A, van Eeuwijk JMM, Nurden P, Stritt S, Heib T, Aurbach K, Angay O, Cherpokova D, Heinz N, Baig AA, Gorelashvili MG, Gerner F, Heinze KG, Ware J, Krohne G, Ruggeri ZM, Nurden AT, Schulze H, Modlich U, Pleines I, Brakebusch C, Nieswandt B. (2017)
A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis. 
Nat Commun. 2017 Jun 15;8:15838. doi: 10.1038/ncomms15838. 
Zur Publikation. 

Bender M, Stegner D, Nieswandt B. (2017)
Model systems for platelet receptor shedding. 
Platelets. 2017 Jun;28(4):325-332. doi: 10.1080/09537104.2016.1195491. Epub 2016 Jun 23. 
Zur Publikation. REVIEW.

Ta-Shma A, Zhang K, Salimova E, Zernecke A, Sieiro-Mosti D, Stegner D, Furtado M, Shaag A, Perles Z, Nieswandt B, Rein AJ, Rosenthal N, Neiman AM, Elpeleg O. (2017)
Congenital valvular defects associated with deleterious mutations in the PLD1 gene. 
J Med Genet. 2017 Apr;54(4):278-286. doi: 10.1136/jmedgenet-2016-104259. Epub 2016 Oct 31. 
Zur Publikation.

Deppermann C, Kraft P, Volz J, Schuhmann MK, Beck S, Wolf K, Stegner D, Stoll G, Nieswandt B.
Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice. 
Blood. 2017 Mar 23;129(12):1702-1706. doi: 10.1182/blood-2016-12-750711. Epub 2017 Jan 11. 
Zur Publikation.

Pleines I, Woods J, Chappaz S, Kew V, Foad N, Ballester-Beltrán J, Aurbach K, Lincetto C, Lane RM, Schevzov G, Alexander WS, Hilton DJ, Astle WJ, Downes K, Nurden P, Westbury SK, Mumford AD, Obaji SG, Collins PW, Delerue F, Ittner LM, Bryce NS, Holliday M, Lucas CA, Hardeman EC, Ouwehand WH, Gunning PW, Turro E, Tijssen MR, Kile BT.
Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia.
J Clin Invest. 2017 Mar 1;127(3):814-829. doi: 10.1172/JCI86154. Epub 2017 Jan 30.
Zur Publikation.

Pierre S, Linke B, Suo J, Tarighi N, Del Turco D, Thomas D, Ferreiros N, Stegner D, Frölich S, Sisignano M, Meyer Dos Santos S, deBruin N, Nüsing RM, Deller T, Nieswandt B, Geisslinger G, Scholich K. (2017)
GPVI and Thromboxane Receptor on Platelets Promote Proinflammatory Macrophage Phenotypes during Cutaneous Inflammation. 
J Invest Dermatol. 2017 Mar;137(3):686-695. doi: 10.1016/j.jid.2016.09.036. Epub 2016 Nov 3. 
Zur Publikation.

Latorre-Rey LJ, Wintterle S, Dütting S, Kohlscheen S, Abel T, Schenk F, Wingert S, Rieger MA, Nieswandt B, Heinz N, Modlich U. (2017)
Targeting expression to megakaryocytes and platelets by lineage-specific lentiviral vectors.
J Thromb Haemost. 2017 Feb;15(2):341-355. doi: 10.1111/jth.13582. 
Zur Publikation.

Schuhmann MK, Guthmann J, Stoll G, Nieswandt B, Kraft P, Kleinschnitz C. (2017)
Blocking of platelet glycoprotein receptor Ib reduces "thrombo-inflammation" in mice with acute ischemic stroke. 
J Neuroinflammation. 2017 Jan 21;14(1):18. doi: 10.1186/s12974-017-0792-y. 
Zur Publikation.

Vorlova S, Koch M, Manthey HD, Cochain C, Busch M, Chaudhari SM, Stegner D, Yepes M, Lorenz K, Nolte MW, Nieswandt B, Zernecke A. (2017)
Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice.
Thromb Haemost. 2017 Jan 5;117(1):176-187. doi: 10.1160/TH16-06-0466. Epub 2016 Oct 27. 
Zur Publikation.

Baig AA, Haining EJ, Geuss E, Beck S, Swieringa F, Wanitchakool P, Schuhmann MK, Stegner D, Kunzelmann K, Kleinschnitz C, Heemskerk JW, Braun A, Nieswandt B (2016)
TMEM16F-Mediated Platelet Membrane Phospholipid Scrambling Is Critical for Hemostasis and Thrombosis but not Thromboinflammation in Mice-Brief Report. Arterioscler Thromb Vasc Biol 36(11):2152-2157.

Brandl A, Daum P, Brenner S, Schulz SR, Yap DY, Bösl MR, Wittmann J, Schuh W, Jäck HM (2016)
The microprocessor component, DGCR8, is essential for early B-cell development in mice.
Eur J Immunol 46(12):2710-2718.

Chen W, Spitzl A, Mathes D, Nikolaev VO, Werner F, Weirather J, ?piranec K, Röck K, Fischer JW, Kämmerer U, Stegner D, Baba HA, Hofmann U, Frantz S, Kuhn M (2016) Endothelial Actions of ANP Enhance Myocardial Inflammatory Infiltration in the Early Phase After Acute Infarction.
Circ Res 119(2):237-48.

Chillo O, Kleinert EC, Lautz T, Lasch M, Pagel JI, Heun Y, Troidl K, Fischer S, Caballero-Martinez A, Mauer A, Kurz ARM, Assmann G, Rehberg M, Kanse SM, Nieswandt B, Walzog B, Reichel CA, Mannell H, Preissner KT, Deindl E (2016)
Perivascular Mast Cells Govern Shear Stress-Induced Arteriogenesis by Orchestrating Leukocyte Function.
Cell Rep 16(8):2197-2207.

Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T (2016)
Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival.
Elife 5.

Göbel K, Pankratz S, Asaridou CM, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG (2016)
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Nat Commun 7:11626.

Hopp S, Albert-Weissenberger C, Mencl S, Bieber M, Schuhmann MK, Stetter C, Nieswandt B, Schmidt PM, Monoranu CM, Alafuzoff I, Marklund N, Nolte MW, Sirén AL, Kleinschnitz C (2016)
Targeting coagulation factor XII as a novel therapeutic option in brain trauma.
Ann Neurol 79(6):970-82.

Kunz M, Wolf B, Schulze H, Atlan D, Walles T, Walles H, Dandekar T (2016)
Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools.
Genes (Basel) 8:1.

Mattheij NJ, Braun A, van Kruchten R, Castoldi E, Pircher J, Baaten CC, Wülling M, Kuijpers MJ, Köhler R, Poole AW, Schreiber R, Vortkamp A, Collins PW, Nieswandt B, Kunzelmann K, Cosemans JM, Heemskerk JW (2016)
Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.
FASEB J 30(2):727-37.

May F, Krupka J, Fries M, Thielmann I, Pragst I, Weimer T, Panousis C, Nieswandt B, Stoll G, Dickneite G, Schulte S, Nolte MW (2016)
FXIIa inhibitor rHA-Infestin-4: Safe thromboprotection in experimental venous, arterial and foreign surface-induced thrombosis.
Br J Haematol 173(5):769-78.

Pachel C, Mathes D, Arias-Loza AP, Heitzmann W, Nordbeck P, Deppermann C, Lorenz V, Hofmann U, Nieswandt B, Frantz S (2016)
Inhibition of Platelet GPVI Protects Against Myocardial Ischemia-Reperfusion Injury.
Arterioscler Thromb Vasc Biol 36(4):629-35.

Regn M, Laggerbauer B, Jentzsch C, Ramanujam D, Ahles A, Sichler S, Calzada-Wack J, Koenen RR, Braun A, Nieswandt B, Engelhardt S (2016)
Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium.
J Mol Cell Cardiol 99:57-64.

Semeniak D, Kulawig R, Stegner D, Meyer I, Schwiebert S, Bösing H, Eckes B, Nieswandt B, Schulze H (2016)
Proplatelet formation is selectively inhibited by collagen type I through Syk-independent GPVI signaling.
J Cell Sci 129(18):3473-84.

Stegner D, Popp M, Lorenz V, Wax JK, Gessner JE, Nieswandt B (2016)
Fc?RIIB on liver sinusoidal endothelial cells is essential for antibody-induced GPVI ectodomain shedding in mice.
Blood 128(6):862-5.

Stritt S, Nurden P, Favier R, Favier M, Ferioli S, Gotru SK, van Eeuwijk JM, Schulze H, Nurden AT, Lambert MP, Turro E, Burger-Stritt S, Matsushita M, Mittermeier L, Ballerini P, Zierler S, Laffan MA, Chubanov V, Gudermann T, Nieswandt B, Braun A (2016)
Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture.
Nat Commun 7:11097.

Stritt S, Nurden P, Turro E, Greene D, Jansen SB, Westbury SK, Petersen R, Astle WJ, Marlin S, Bariana TK, Kostadima M, Lentaigne C, Maiwald S, Papadia S, Kelly AM, Stephens JC, Penkett CJ, Ashford S, Tuna S, Austin S, Bakchoul T, Collins P, Favier R, Lambert MP, Mathias M, Millar CM, Mapeta R, Perry DJ, Schulman S, Simeoni I, Thys C, BRIDGE-BPD Consortium , Gomez K, Erber WN, Stirrups K, Rendon A, Bradley JR, van Geet C, Raymond FL, Laffan MA, Nurden AT, Nieswandt B, Richardson S, Freson K, Ouwehand WH, Mumford AD (2016)
A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss.
Blood 127(23):2903-14.

Trujillo Viera J, El-Merahbi R, Nieswandt B, Stegner D, Sumara G (2016)
Phospholipases D1 and D2 Suppress Appetite and Protect against Overweight.
PLoS ONE 11(6):e0157607.

van Eeuwijk JM, Stegner D, Lamb DJ, Kraft P, Beck S, Thielmann I, Kiefer F, Walzog B, Stoll G, Nieswandt B (2016)
The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction.
Arterioscler Thromb Vasc Biol 36(6):1247-53.

Wolf K, Braun A, Haining EJ, Tseng YL, Kraft P, Schuhmann MK, Gotru SK, Chen W, Hermanns HM, Stoll G, Lesch KP, Nieswandt B (2016)
Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice.
PLoS ONE 11(1):e0147664.

Alshehri OM, Hughes CE, Montague S, Watson SK, Frampton J, Bender M, Watson SP (2015)
Fibrin activates GPVI in human and mouse platelets.
Blood 126(13):1601-8.

Ammar MR, Thahouly T, Hanauer A, Stegner D, Nieswandt B, Vitale N (2015)
PLD1 participates in BDNF-induced signalling in cortical neurons.
Sci Rep 5:14778.

Andres O, Schulze H, Speer CP (2015)
Platelets in neonates: central mediators in haemostasis, antimicrobial defence and inflammation.
Thromb Haemost 113(1):3-12.

Cherpokova D, Bender M, Morowski M, Kraft P, Schuhmann MK, Akbar SM, Sultan CS, Hughes CE, Kleinschnitz C, Stoll G, Dragone LL, Watson SP, Tomlinson MG, Nieswandt B (2015)
SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice.
Blood 125(1):185-94.

Crazzolara R, Maurer K, Schulze H, Zieger B, Zustin J, Schulz AS (2015)
A new mutation in the KINDLIN-3 gene ablates integrin-dependent leukocyte, platelet, and osteoclast function in a patient with leukocyte adhesion deficiency-III.
Pediatr Blood Cancer 62(9):1677-9.

Devanathan V, Hagedorn I, Köhler D, Pexa K, Cherpokova D, Kraft P, Singh M, Rosenberger P, Stoll G, Birnbaumer L, Piekorz RP, Beer-Hammer S, Nieswandt B, Nürnberg B (2015)
Platelet Gi protein G?i2 is an essential mediator of thrombo-inflammatory organ damage in mice.
Proc Natl Acad Sci U S A 112(20):6491-6.

Drube S, Weber F, Loschinski R, Beyer M, Rothe M, Rabenhorst A, Göpfert C, Meininger I, Diamanti MA, Stegner D, Häfner N, Böttcher M, Reinecke K, Herdegen T, Greten FR, Nieswandt B, Hartmann K, Krämer OH, Kamradt T (2015)
Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells.
Oncotarget 6(7):5354-68.

Dütting S, Heidenreich J, Cherpokova D, Amin E, Zhang SC, Ahmadian MR, Brakebusch C, Nieswandt B (2015)
Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets.
J Thromb Haemost 13(5):827-38.

Flierl U, Nero TL, Lim B, Arthur JF, Yao Y, Jung SM, Gitz E, Pollitt AY, Zaldivia MT, Jandrot-Perrus M, Schäfer A, Nieswandt B, Andrews RK, Parker MW, Gardiner EE, Peter K (2015) Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators.
J Exp Med 212(2):129-37.

Foster E, Wildner H, Tudeau L, Haueter S, Ralvenius WT, Jegen M, Johannssen H, Hösli L, Haenraets K, Ghanem A, Conzelmann KK, Bösl M, Zeilhofer HU (2015)
Targeted ablation, silencing, and activation establish glycinergic dorsal horn neurons as key components of a spinal gate for pain and itch.
Neuron 85(6):1289-304.

Göb E, Reymann S, Langhauser F, Schuhmann MK, Kraft P, Thielmann I, Göbel K, Brede M, Homola G, Solymosi L, Stoll G, Geis C, Meuth SG, Nieswandt B, Kleinschnitz C (2015)
Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation.
Ann Neurol 77(5):784-803.

Gros A, Syvannarath V, Lamrani L, Ollivier V, Loyau S, Goerge T, Nieswandt B, Jandrot-Perrus M, Ho-Tin-Noé B (2015)
Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice.    
Blood 126(8):1017-26.

Kraft P, Schuhmann MK, Fluri F, Lorenz K, Zernecke A, Stoll G, Nieswandt B, Kleinschnitz C (2015)
Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke.
Stroke 46(12):3502-6.

Lorenz V, Stegner D, Stritt S, Vögtle T, Kiefer F, Witke W, Schymeinsky J, Watson SP, Walzog B, Nieswandt B (2015)
Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization.
Blood 125(26):4069-77.

Lowe KL, Finney BA, Deppermann C, Hägerling R, Gazit SL, Frampton J, Buckley C, Camerer E, Nieswandt B, Kiefer F, Watson SP (2015)
Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development.
Blood 125(24):3769-77.

Lowe KL, Navarro-Núñez L, Bénézech C, Nayar S, Kingston BL, Nieswandt B, Barone F, Watson SP, Buckley CD, Desanti GE (2015)
The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state.
Eur J Immunol 45(9):2484-93.

Mammadova-Bach E, Ollivier V, Loyau S, Schaff M, Dumont B, Favier R, Freyburger G, Latger-Cannard V, Nieswandt B, Gachet C, Mangin PH, Jandrot-Perrus M (2015)
Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation. Blood 126(5):683-91.

Maurer E, Schaff M, Receveur N, Bourdon C, Mercier L, Nieswandt B, Dubois C, Jandrot-Perrus M, Goetz JG, Lanza F, Gachet C, Mangin PH (2015)
Fibrillar cellular fibronectin supports efficient platelet aggregation and procoagulant activity.
Thromb Haemost 114(6):1175-88.

Michaelis M, Nieswandt B, Stegner D, Eilers J, Kraft R (2015)
STIM1, STIM2, and Orai1 regulate store-operated calcium entry and purinergic activation of microglia.
Glia 63(4):652-63.

Popp M, Thielmann I, Nieswandt B, Stegner D (2015)
Normal Platelet Integrin Function in Mice Lacking Hydrogen Peroxide-Induced Clone-5 (Hic-5).
PLoS ONE 10(7):e0133429.

Schuhmann MK, Kraft P, Stoll G, Lorenz K, Meuth SG, Wiendl H, Nieswandt B, Sparwasser T, Beyersdorf N, Kerkau T, Kleinschnitz C (2015)
CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke.
J Cereb Blood Flow Metab 35(1):6-10.

Schwarzenberger C, Sradnick J, Lerea KM, Goligorsky MS, Nieswandt B, Hugo CP, Hohenstein B (2015)
Platelets are relevant mediators of renal injury induced by primary endothelial lesions. Am J Physiol Renal Physiol 308(11):F1238-46.

Sogkas G, Vögtle T, Rau E, Gewecke B, Stegner D, Schmidt RE, Nieswandt B, Gessner JE (2015)
Orai1 controls C5a-induced neutrophil recruitment in inflammation.
Eur J Immunol 45(7):2143-53.

Stritt S, Wolf K, Lorenz V, Vögtle T, Gupta S, Bösl MR, Nieswandt B (2015)
Rap1-GTP-interacting adaptor molecule (RIAM) is dispensable for platelet integrin activation and function in mice.
Blood 125(2):219-22.

Subramaniam S, Thielmann I, Morowski M, Pragst I, Sandset PM, Nieswandt B, Etscheid M, Kanse SM (2015)
Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP).
Thromb Haemost 113(4):870-80.

Teng S, Stegner D, Chen Q, Hongu T, Hasegawa H, Chen L, Kanaho Y, Nieswandt B, Frohman MA, Huang P (2015)
Phospholipase D1 facilitates second-phase myoblast fusion and skeletal muscle regeneration.
Mol Biol Cell 26(3):506-17.

Verhenne S, Denorme F, Libbrecht S, Vandenbulcke A, Pareyn I, Deckmyn H, Lambrecht A, Nieswandt B, Kleinschnitz C, Vanhoorelbeke K, De Meyer SF (2015)
Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice.
Blood 126(14):1715-22.

Vögtle T, Cherpokova D, Bender M, Nieswandt B (2015)
Targeting platelet receptors in thrombotic and thrombo-inflammatory disorders. Hamostaseologie 35(3):235-43.

Weider M, Wegener A, Schmitt C, Küspert M, Hillgärtner S, Bösl MR, Hermans-Borgmeyer I, Nait-Oumesmar B, Wegner M (2015)
Elevated in vivo levels of a single transcription factor directly convert satellite glia into oligodendrocyte-like cells.
PLoS Genet 11(2):e1005008.

Westbury SK, Turro E, Greene D, Lentaigne C, Kelly AM, Bariana TK, Simeoni I, Pillois X, Attwood A, Austin S, Jansen SB, Bakchoul T, Crisp-Hihn A, Erber WN, Favier R, Foad N, Gattens M, Jolley JD, Liesner R, Meacham S, Millar CM, Nurden AT, Peerlinck K, Perry DJ, Poudel P, Schulman S, Schulze H, Stephens JC, Furie B, Robinson PN, van Geet C, Rendon A, Gomez K, Laffan MA, Lambert MP, Nurden P, Ouwehand WH, Richardson S, Mumford AD, Freson K, BRIDGE-BPD Consortium (2015)
Human phenotype ontology annotation and cluster analysis to unravel genetic defects in 707 cases with unexplained bleeding and platelet disorders.
Genome Med 7(1):36.

Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze K, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B (2014)
Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect.
Nat Commun 5:4746.

Burkhardt U, Stegner D, Hattingen E, Beyer S, Nieswandt B, Klein J (2014)
Impaired brain development and reduced cognitive function in phospholipase D-deficient mice.
Neurosci Lett 572:48-52.

Chen W, Thielmann I, Gupta S, Subramanian H, Stegner D, van Kruchten R, Dietrich A, Gambaryan S, Heemskerk JW, Hermanns HM, Nieswandt B, Braun A (2014)
Orai1-induced store-operated Ca(2+) entry enhances phospholipase activity and modulates canonical transient receptor potential channel 6 function in murine platelets.
J Thromb Haemost 12(4):528-39.

Dénes Á, Pradillo JM, Drake C, Sharp A, Warn P, Murray KN, Rohit B, Dockrell DH, Chamberlain J, Casbolt H, Francis S, Martinecz B, Nieswandt B, Rothwell NJ, Allan SM (2014)
Streptococcus pneumoniae worsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ib?.
Ann Neurol 75(5):670-83.

Dütting S, Vögtle T, Morowski M, Schiessl S, Schäfer CM, Watson SK, Hughes CE, Ackermann JA, Radtke D, Hermanns HM, Watson SP, Nitschke L, Nieswandt B (2014)
Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets.
Circ Res 114(3):444-53.

Göbel K, Schuhmann MK, Pankratz S, Stegner D, Herrmann AM, Braun A, Breuer J, Bittner S, Ruck T, Wiendl H, Kleinschnitz C, Nieswandt B, Meuth SG (2014) Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis.
Eur J Immunol 44(8):2295-305.

Hess PR, Rawnsley DR, Jakus Z, Yang Y, Sweet DT, Fu J, Herzog B, Lu M, Nieswandt B, Oliver G, Makinen T, Xia L, Kahn ML (2014)
Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life.
J Clin Invest 124(1):273-84.

Hillgruber C, Steingräber AK, Pöppelmann B, Denis CV, Ware J, Vestweber D, Nieswandt B, Schneider SW, Goerge T (2014)
Blocking von Willebrand factor for treatment of cutaneous inflammation.
J Invest Dermatol 134(1):77-86.

Hofmann S, Braun A, Pozgaj R, Morowski M, Vögtle T, Nieswandt B (2014)
Mice lacking the SLAM family member CD84 display unaltered platelet function in hemostasis and thrombosis.
PLoS ONE 9(12):e115306.

Kraft P, Drechsler C, Gunreben I, Nieswandt B, Stoll G, Heuschmann PU, Kleinschnitz C (2014)
Von Willebrand factor regulation in patients with acute and chronic cerebrovascular disease: a pilot, case-control study.
PLoS ONE 9(6):e99851.

Morowski M, Brachs S, Mielenz D, Nieswandt B, Dütting S (2014)
The adaptor protein Swiprosin-1/EFhd2 is dispensable for platelet function in mice.
PLoS ONE 9(9):e107139.

Pollitt AY, Poulter NS, Gitz E, Navarro-Nuñez L, Wang YJ, Hughes CE, Thomas SG, Nieswandt B, Douglas MR, Owen DM, Jackson DG, Dustin ML, Watson SP (2014)
Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells.
J Biol Chem 289(52):35695-710.

Shida Y, Rydz N, Stegner D, Brown C, Mewburn J, Sponagle K, Danisment O, Crawford B, Vidal B, Hegadorn CA, Pruss CM, Nieswandt B, Lillicrap D (2014)
Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and ?2?1-mediated collagen binding in thrombus formation.
Blood 124(11):1799-807.

Stegner D, Haining EJ, Nieswandt B (2014)
Targeting glycoprotein VI and the immunoreceptor tyrosine-based activation motif signaling pathway.
Arterioscler Thromb Vasc Biol 34(8):1615-20.

Stritt S, Thielmann I, Dütting S, Stegner D, Nieswandt B (2014)
Phospholipase D is a central regulator of collagen I-induced cytoskeletal rearrangement and podosome formation in megakaryocytes.
J Thromb Haemost 12(8):1364-71.

Suo J, Linke B, Meyer dos Santos S, Pierre S, Stegner D, Zhang DD, Denis CV, Geisslinger G, Nieswandt B, Scholich K (2014)
Neutrophils mediate edema formation but not mechanical allodynia during zymosan-induced inflammation.
J Leukoc Biol 96(1):133-42.

Wegener JW, Loga F, Stegner D, Nieswandt B, Hofmann F (2014)
Phospholipase D1 is involved in ?1-adrenergic contraction of murine vascular smooth muscle.
FASEB J 28(3):1044-8.

Ammar MR, Humeau Y, Hanauer A, Nieswandt B, Bader MF, Vitale N (2013)
The Coffin-Lowry syndrome-associated protein RSK2 regulates neurite outgrowth through phosphorylation of phospholipase D1 (PLD1) and synthesis of phosphatidic acid. J Neurosci 33(50):19470-9.

Bender M, May F, Lorenz V, Thielmann I, Hagedorn I, Finney BA, Vögtle T, Remer K, Braun A, Bösl M, Watson SP, Nieswandt B (2013)
Combined in vivo depletion of glycoprotein VI and C-type lectin-like receptor 2 severely compromises hemostasis and abrogates arterial thrombosis in mice.
Arterioscler Thromb Vasc Biol 33(5):926-34.

Bittner S, Ruck T, Schuhmann MK, Herrmann AM, Moha ou Maati H, Bobak N, Göbel K, Langhauser F, Stegner D, Ehling P, Borsotto M, Pape HC, Nieswandt B, Kleinschnitz C, Heurteaux C, Galla HJ, Budde T, Wiendl H, Meuth SG (2013)
Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS.
Nat Med 19(9):1161-5.

Herzog BH, Fu J, Wilson SJ, Hess PR, Sen A, McDaniel JM, Pan Y, Sheng M, Yago T, Silasi-Mansat R, McGee S, May F, Nieswandt B, Morris AJ, Lupu F, Coughlin SR, McEver RP, Chen H, Kahn ML, Xia L (2013)
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2.
Nature 502(7469):105-9.

Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Göbel K, Schuhmann MK, Langhauser F, Helluy X, Schwarz T, Bittner S, Mayer CT, Brede M, Varallyay C, Pham M, Bendszus M, Jakob P, Magnus T, Meuth SG, Iwakura Y, Zernecke A, Sparwasser T, Nieswandt B, Stoll G, Wiendl H (2013)
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Blood 121(4):679-91.

Kraft P, Göb E, Schuhmann MK, Göbel K, Deppermann C, Thielmann I, Herrmann AM, Lorenz K, Brede M, Stoll G, Meuth SG, Nieswandt B, Pfeilschifter W, Kleinschnitz C (2013)
FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-inflammation but not by direct neuroprotection.
Stroke 44(11):3202-10.

Morowski M, Vögtle T, Kraft P, Kleinschnitz C, Stoll G, Nieswandt B. (2013) Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice. Blood 121(24):4938-47.

Pfeiffer V, Götz R, Xiang C, Camarero G, Braun A, Zhang Y, Blum R, Heinsen H, Nieswandt B, Rapp UR (2013)
Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum.
PLoS ONE 8(3):e58259.

Pleines I, Dütting S, Cherpokova D, Eckly A, Meyer I, Morowski M, Krohne G, Schulze H, Gachet C, Debili N, Brakebusch C, Nieswandt B (2013)
Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42.
Blood 122(18):3178-87.

Schaff M, Tang C, Maurer E, Bourdon C, Receveur N, Eckly A, Hechler B, Arnold C, de Arcangelis A, Nieswandt B, Denis CV, Lefebvre O, Georges-Labouesse E, Gachet C, Lanza F, Mangin PH (2013)
Integrin ?6?1 is the main receptor for vascular laminins and plays a role in platelet adhesion, activation, and arterial thrombosis.    
Circulation 128(5):541-52.

Stegner D, Thielmann I, Kraft P, Frohman MA, Stoll G, Nieswandt B (2013) Pharmacological inhibition of phospholipase D protects mice from occlusive thrombus formation and ischemic stroke--brief report.
Arterioscler Thromb Vasc Biol 33(9):2212-7.

Timofeev O, Schlereth K, Wanzel M, Braun A, Nieswandt B, Pagenstecher A, Rosenwald A, Elsässer HP, Stiewe T (2013)
p53 DNA binding cooperativity is essential for apoptosis and tumor suppression in vivo. Cell Rep 3(5):1512-25.

Chen Q, Hongu T, Sato T, Zhang Y, Ali W, Cavallo JA, van der Velden A, Tian H, Di Paolo G, Nieswandt B, Kanaho Y, Frohman MA (2012)
Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis.
Sci Signal 5(249):ra79.

Dramane G, Abdoul-Azize S, Hichami A, Vögtle T, Akpona S, Chouabe C, Sadou H, Nieswandt B, Besnard P, Khan NA (2012)
STIM1 regulates calcium signaling in taste bud cells and preference for fat in mice.
J Clin Invest 122(6):2267-82.

Dütting S, Bender M, Nieswandt B (2012)
Platelet GPVI: a target for antithrombotic therapy?!
Trends Pharmacol Sci 33(11):583-90.

Gupta S, Braun A, Morowski M, Premsler T, Bender M, Nagy Z, Sickmann A, Hermanns HM, Bösl M, Nieswandt B (2012)
CLP36 is a negative regulator of glycoprotein VI signaling in platelets.
Circ Res 111(11):1410-20.

Heydenreich N, Nolte MW, Göb E, Langhauser F, Hofmeister M, Kraft P, Albert-Weissenberger C, Brede M, Varallyay C, Göbel K, Meuth SG, Nieswandt B, Dickneite G, Stoll G, Kleinschnitz C (2012)
C1-inhibitor protects from brain ischemia-reperfusion injury by combined antiinflammatory and antithrombotic mechanisms.
Stroke 43(9):2457-67.

Hofmann S, Vögtle T, Bender M, Rose-John S, Nieswandt B (2012)
The SLAM family member CD84 is regulated by ADAM10 and calpain in platelets.
J Thromb Haemost 10(12):2581-92.

Königsberger S, Prodöhl J, Stegner D, Weis V, Andreas M, Stehling M, Schumacher T, Böhmer R, Thielmann I, van Eeuwijk JM, Nieswandt B, Kiefer F (2012)
Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state.
EMBO J 31(15):3363-74.

Kraft P, Nieswandt B, Stoll G, Kleinschnitz C (2012)
Acute ischemic stroke. New approaches to antithrombotic treatment.
Nervenarzt 83(4):435-49.

Langer HF, Choi EY, Zhou H, Schleicher R, Chung KJ, Tang Z, Göbel K, Bdeir K, Chatzigeorgiou A, Wong C, Bhatia S, Kruhlak MJ, Rose JW, Burns JB, Hill KE, Qu H, Zhang Y, Lehrmann E, Becker KG, Wang Y, Simon DI, Nieswandt B, Lambris JD, Li X, Meuth SG, Kubes P, Chavakis T (2012)
Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis. Circ Res 110(9):1202-10.

Langhauser F, Göb E, Kraft P, Geis C, Schmitt J, Brede M, Göbel K, Helluy X, Pham M, Bendszus M, Jakob P, Stoll G, Meuth SG, Nieswandt B, McCrae KR, Kleinschnitz C (2012)
Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation.
Blood 120(19):4082-92.

Lonsdorf AS, Krämer BF, Fahrleitner M, Schönberger T, Gnerlich S, Ring S, Gehring S, Schneider SW, Kruhlak MJ, Meuth SG, Nieswandt B, Gawaz M, Enk AH, Langer HF (2012)
Engagement of ?IIb?3 (GPIIb/IIIa) with ???3 integrin mediates interaction of melanoma cells with platelets: a connection to hematogenous metastasis.
J Biol Chem 287(3):2168-78.

Mazharian A, Wang YJ, Mori J, Bem D, Finney B, Heising S, Gissen P, White JG, Berndt MC, Gardiner EE, Nieswandt B, Douglas MR, Campbell RD, Watson SP, Senis YA (2012)
Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function.
Sci Signal 5(248):ra78.

Meyer I, Kunert S, Schwiebert S, Hagedorn I, Italiano JE, Dütting S, Nieswandt B, Bachmann S, Schulze H (2012)
Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10.
Blood 120(17):3594-602.

Pham M, Stoll G, Nieswandt B, Bendszus M, Kleinschnitz C (2012)
Blood coagulation factor XII--a neglected player in stroke pathophysiology.
J Mol Med 90(2):119-26.

Pleines I, Hagedorn I, Gupta S, May F, Chakarova L, van Hengel J, Offermanns S, Krohne G, Kleinschnitz C, Brakebusch C, Nieswandt B (2012)
Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis.
Blood 119(4):1054-63.

Ponnuswamy P, Schröttle A, Ostermeier E, Grüner S, Huang PL, Ertl G, Hoffmann U, Nieswandt B, Kuhlencordt PJ (2012)
eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice.
PLoS ONE 7(1):e30193.

Ramanathan G, Gupta S, Thielmann I, Pleines I, Varga-Szabo D, May F, Mannhalter C, Dietrich A, Nieswandt B, Braun A (2012)
Defective diacylglycerol-induced Ca2+ entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets.
J Thromb Haemost 10(3):419-29.

Schönberger T, Ziegler M, Borst O, Konrad I, Nieswandt B, Massberg S, Ochmann C, Jürgens T, Seizer P, Langer H, Münch G, Ungerer M, Preissner KT, Elvers M, Gawaz M (2012)
The dimeric platelet collagen receptor GPVI-Fc reduces platelet adhesion to activated endothelium and preserves myocardial function after transient ischemia in mice.
Am J Physiol Cell Physiol 303(7):C757-66.

Sodero AO, Vriens J, Ghosh D, Stegner D, Brachet A, Pallotto M, Sassoè-Pognetto M, Brouwers JF, Helms JB, Nieswandt B, Voets T, Dotti CG (2012)
Cholesterol loss during glutamate-mediated excitotoxicity.
EMBO J 31(7):1764-73.

Thielmann I, Stegner D, Kraft P, Hagedorn I, Krohne G, Kleinschnitz C, Stoll G, Nieswandt B (2012)
Redundant functions of phospholipases D1 and D2 in platelet ?-granule release.
J Thromb Haemost 10(11):2361-72.

van Kruchten R, Braun A, Feijge MA, Kuijpers MJ, Rivera-Galdos R, Kraft P, Stoll G, Kleinschnitz C, Bevers EM, Nieswandt B, Heemskerk JW (2012)
Antithrombotic potential of blockers of store-operated calcium channels in platelets.
Arterioscler Thromb Vasc Biol 32(7):1717-23.