Publikationen der ibdw

Beyersdorf, N.;Afshar, B.;Pelin, D.;Bauser, M.;Kaiser, E.;Lamers, J.;Pätkau, J.;Heil, M.;Göpfert, D.;Hepp, H.;Al Hassan, W.;Kerkau, T.;Kerwagen, F.;Jahns, R.;Boivin-Jahns, V.;Frantz, S.;Ramos, G.;Hofmann, U.;Störk, S.;Morbach, C. Cardioimmunologic Response Patterns After an Acute Heart Failure Event: Design and First Results of AHF-ImmunoCS. ESC Heart Failure. 12(6):4503-4512. (2025)
doi:10.1002/ehf2.70005

Morbach, C.;Moser, N.;Cejka, V.;Stach, M.;Sahiti, F.;Kerwagen, F.;Frantz, S.;Pryss, R.;Gelbrich, G.;Heuschmann, P. U.;Störk, S.;on behalf of the STAAB consortium;Maack, C.;Ertl, G.;Fassnacht, M.;Wanner, C.;Leyh, R.;Volkmann, J.;Deckert, J.;Faller, H.;Jahns, R. Determinants and reference values of the 6-min walk distance in the general population—results of the population-based STAAB cohort study. Clin Res Cardiol. 114(9):1098-1108. (2025)
doi:10.1007/s00392-023-02373-3

Brand, T.;Lukannek, A.-K.;Jahns, R.;Lorenz, K. From “contraindicated” to “first line” - Current mechanistic insights beyond canonical O-receptor signaling. CURRENT OPINION IN PHARMACOLOGY. 76. (2024) 
doi:10.1016/j.coph.2024.102458

Burmeister, T.;Ströh, A.-S.;Kehden, B.;Trautmann, H.;Meyer, C.;Marschalek, R.;Larghero, P.;Schwartz, S.;Steffen, B.;Spriewald, B.;Heinicke, T.;Jäkel, N.;Westermann, J.;Nachtkamp, K.;Viardot, A.;Topp, M. S.;Neumann, M.;Baldus, C. D.;Gökbuget, N.;Brüggemann, M. Measurable residual disease quantification in adult patients with KMT2A-rearranged acute lymphoblastic leukemia. Leukemia. 38(7):1600-1603. (2024) 
doi:10.1038/s41375-024-02209-7

Eklund, N.;Engels, C.;Neumann, M.;Strug, A.;van Enckevort, E.;Baber, R.;Bloemers, M.;Debucquoy, A.;van der Lugt, A.;Müller, H.;Parkkonen, L.;Quinlan, P. R.;Urwin, E.;Holub, P.;Silander, K.;Anton, G. Update of the Minimum Information About BIobank Data Sharing (MIABIS) Core Terminology to the 3(rd) Version. Biopreserv Biobank. 22(4):346-362. (2024)
doi:10.1089/bio.2023.0074

Fender, J.;Kloecker, J.;Boivin-Jahns, V.;Ravens, U.;Jahns, R.;Lorenz, K. “Cardiac glycosides”-quo vaditis?-past, present, and future? NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 397(12):9521-9531. (2024)
doi:10.1007/s00210-024-03285-3

Sahiti, F.;Cejka, V.;Schmidbauer, L.;Albert, J.;Kerwagen, F.;Frantz, S.;Gelbrich, G.;Heuschmann, P. U.;Störk, S.;Morbach, C.;Maack, C.;Ertl, G.;Wanner, C.;Leyh, R.;Volkmann, J.;Deckert, J.;Faller, H.;Jahns, R. Prognostic Utility of Pericardial Effusion in the General Population: Findings From the STAAB Cohort Study. JAHA. 13(12):e035549. (2024)
doi:10.1161/JAHA.124.035549

Wittner, R.;Holub, P.;Mascia, C.;Frexia, F.;Müller, H.;Plass, M.;Allocca, C.;Betsou, F.;Burdett, T.;Cancio, I.;Chapman, A.;Chapman, M.;Courtot, M.;Curcin, V.;Eder, J.;Elliot, M.;Exter, K.;Goble, C.;Golebiewski, M.;Kisler, B.;Kremer, A.;Leo, S.;Lin‐Gibson, S.;Marsano, A.;Mattavelli, M.;Moore, J.;Nakae, H.;Perseil, I.;Salman, A.;Sluka, J.;Soiland‐Reyes, S.;Strambio‐De‐Castillia, C.;Sussman, M.;Swedlow, J. R.;Zatloukal, K.;Geiger, J. Toward a common standard for data and specimen provenance in life sciences. Learning Health Systems. 8(1):e10365. (2024)
doi:10.1002/lrh2.10365

Zenker, S.;Strech, D.;Jahns, R.;Müller, G.;Prasser, F.;Schickhardt, C.;Schmidt, G.;Semler, S. C.;Winkler, E.;Drepper, J. National standardisierter Broad Consent in der Praxis: erste Erfahrungen, aktuelle Entwicklungen und kritische Betrachtungen. Bundesgesundheitsbl. 67(6):637-647. (2024)
doi:10.1007/s00103-024-03878-6

Geiger, J.;Fuchs, J.;Starke, M.;Neumann, M.;Baber, R.;Nussbeck, S. Y.;Kiehntopf, M.;Specht, C.;Illig, T.;Hummel, M.;Jahns, R. GBA/GBN-position on the feedback of incidental findings in biobank-based research: consensus-based workflow for hospital-based biobanks. Eur J Hum Genet. 31(9):1066-1072. (2023)
doi:10.1038/s41431-023-01299-8

Geiger, J.;Schacter, B.;Coallier, F. Biobanking: A Cornerstone of Biodigital Convergence. Biopreservation and Biobanking. 21(5):439-441. (2023) 
doi:10.1089/bio.2023.29126.editorial

Plass, M.;Wittner, R.;Holub, P.;Frexia, F.;Mascia, C.;Gallo, M.;Müller, H.;Geiger, J. Provenance of specimen and data – A prerequisite for AI development in computational pathology. New Biotechnology. 78:22-28. (2023)
doi:10.1016/j.nbt.2023.09.006

Klingenberg, R.;Holtkamp, F.;Grün, D.;Frey, A.;Jahns, V.;Jahns, R.;Gassenmaier, T.;Hamm, C. W.;Frantz, S.;Keller, T. Use of Serial Changes in Biomarkers vs. Baseline Levels to Predict Left Ventricular Remodelling After STEMI. ESC Heart Failure. 10(1):432-441. (2023)
doi:10.1002/ehf2.14204

Maier, D.;Vehreschild, J. J.;Uhl, B.;Meyer, S.;Berger-Thürmel, K.;Boerries, M.;Braren, R.;Grünwald, V.;Hadaschik, B.;Palm, S.;Singer, S.;Stuschke, M.;Juárez, D.;Delpy, P.;Lambarki, M.;Hummel, M.;Engels, C.;Andreas, S.;Gökbuget, N.;Ihrig, K.;Burock, S.;Keune, D.;Eggert, A.;Keilholz, U.;Schulz, H.;Büttner, D.;Löck, S.;Krause, M.;Esins, M.;Ressing, F.;Schuler, M.;Brandts, C.;Brucker, D. P.;Husmann, G.;Oellerich, T.;Metzger, P.;Voigt, F.;Illert, A. L.;Theobald, M.;Kindler, T.;Sudhof, U.;Reckmann, A.;Schwinghammer, F.;Nasseh, D.;Weichert, W.;Von Bergwelt-Baildon, M.;Bitzer, M.;Malek, N.;Öner, Ö.;Schulze-Osthoff, K.;Bartels, S.;Haier, J.;Ammann, R.;Schmidt, A. F.;Guenther, B.;Janning, M.;Kasper, B.;Loges, S.;Stilgenbauer, S.;Kuhn, P.;Tausch, E.;Runow, S.;Kerscher, A.;Neumann, M.;Breu, M.;Lablans, M.;Serve, H. Profile of the multicenter cohort of the German Cancer Consortium’s Clinical Communication Platform. Eur J Epidemiol. 38(5):573-586. (2023)
doi:10.1007/s10654-023-00990-w

Morbach, C.;Beyersdorf, N.;Moser, N.;Pelin, D.;Afshar, B.;Ramos, G.;Kerkau, T.;Kaiser, E.;Lamers, J.;Pätkau, J.;Sahiti, F.;Albert, J.;Güder, G.;Ertl, G.;Angermann, C. E.;Frantz, S.;Hofmann, U.;Jahns, R.;Jahns, V.;Störk, S. Prevalence of anti‐beta‐1 antibody 6 months after hospitalization for acute heart failure predicts adverse outcome. ESC Heart Failure. 10(5):3227-3231. (2023)
doi:10.1002/ehf2.14509

Traub, J.;Schürmann, P.;Schmitt, D.;Gassenmaier, T.;Fette, G.;Frantz, S.;Störk, S.;Beyersdorf, N.;Boivin-Jahns, V.;Jahns, R.;Hofmann, U.;Frey, A. Features of metabolic syndrome and inflammation independently affect left ventricular function early after first myocardial infarction. International Journal of Cardiology. 370:43-50. (2023)
doi:10.1016/j.ijcard.2022.10.142

Frexia, F.;Mascia, C.;Wittner, R.;Plass, M.;Müller, H.;Geiger, J.;Holub, P. The Common Provenance Model: Capturing Distributed Provenance in Life Sciences Processes. In: Brigitte Séroussi, Patrick Weber, Ferdinand Dhombres, Cyril Grouin, Jan-David Liebe, Sylvia Pelayo, Andrea Pinna, Bastien Rance, Lucia Sacchi, Adrien Ugon, Arriel Benis, Parisis Gallos, eds. Studies in Health Technology and Informatics. IOS Press; 2022. 
doi:10.3233/SHTI220489

Klingler, C.;Von Jagwitz-Biegnitz, M.;Baber, R.;Becker, K.-F.;Dahl, E.;Eibner, C.;Fuchs, J.;Groenewold, M. K.;Hartung, M. L.;Hummel, M.;Jahns, R.;Kirsten, R.;Kopfnagel, V.;Maushagen, R.;Nussbeck, S. Y.;Schoneberg, A.;Winter, T.;Specht, C. Stakeholder engagement to ensure the sustainability of biobanks: a survey of potential users of biobank services. Eur J Hum Genet. 30(12):1344-1354. (2022) 
doi:10.1038/s41431-021-00905-x

Schüttler, C.;Jahns, R.;Prokosch, U.;Wach, S.;Wullich, B. [Biobanks, translational research and medical informatics]. Urologie. 61(7):722-727. (2022)
doi:10.1007/s00120-022-01850-3

Traub, J.;Grondey, K.;Gassenmaier, T.;Schmitt, D.;Fette, G.;Frantz, S.;Boivin-Jahns, V.;Jahns, R.;Stoerk, S.;Stoll, G.;Reiter, T.;Hofmann, U.;Weber, M. S.;Frey, A. Sustained Increase in Serum Glial Fibrillary Acidic Protein after First ST-Elevation Myocardial Infarction. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 23(18). (2022)
doi:10.3390/ijms231810304

Wittner, R.;Mascia, C.;Gallo, M.;Frexia, F.;Mueller, H.;Plass, M.;Geiger, J.;Holub, P. Lightweight Distributed Provenance Model for Complex Real-world Environments. SCIENTIFIC DATA. 9(1). (2022) 
doi:10.1038/s41597-022-01537-6

Zenker, S.;Strech, D.;Ihrig, K.;Jahns, R.;Mueller, G.;Schickhardt, C.;Schmidt, G.;Speer, R.;Winkler, E.;von Kielmansegg, S. G.;Drepper, J. Data protection-compliant broad consent for secondary use of health care data and human biosamples for (bio)medical research: Towards a new German national standard. JOURNAL OF BIOMEDICAL INFORMATICS. 131. (2022)
doi:10.1016/j.jbi.2022.104096

Heiling, S.;Knutti, N.;Scherr, F.;Geiger, J.;Weikert, J.;Rose, M.;Jahns, R.;Ceglarek, U.;Scherag, A.;Kiehntopf, M. Metabolite Ratios as Quality Indicators for Pre-Analytical Variation in Serum and EDTA Plasma. METABOLITES. 11(9). (2021)
doi:10.3390/metabo11090638

Holub, P.;Wittner, R.;Mascia, C.;Frexia, F.;Müller, H.;Plass, M.;Allocca, C.;Betsou, F.;Burdett, T.;Cancio, I.;Chapman, A.;Chapman, M.;Courtot, M.;Curcin, V.;Eder, J.;Elliot, M.;Exter, K.;Fairweather, E.;Goble, C.;Golebiewski, M.;Kisler, B.;Kremer, A.;Lin-Gibson, S.;Marsano, A.;Mattavelli, M.;Moore, J.;Nakae, H.;Perseil, I.;Salman, A.;Sluka, J.;Soiland-Reyes, S.;Strambio-De-Castillia, C.;Sussman, M.;Swedlow, J.;Zatloukal, K.;Geiger, J. Towards a Common Standard for Data and Specimen Provenance in Life Sciences. Published online 2021. 
doi:10.5281/zenodo.5093125

Morbach, C.;Beyersdorf, N.;Kerkau, T.;Ramos, G.;Sahiti, F.;Albert, J.;Jahns, R.;Ertl, G.;Angermann, C. E.;Frantz, S.;Hofmann, U.;Stoerk, S. Adaptive anti-myocardial immune response following hospitalization for acute heart failure. ESC HEART FAILURE. 8(4):3348-3353. (2021)
doi:10.1002/ehf2.13376

Morbach, C.;Gelbrich, G.;Tiffe, T.;Eichner, F. A.;Christa, M.;Mattern, R.;Breunig, M.;Cejka, V.;Wagner, M.;Heuschmann, P. U.;Störk, S.;the STAAB consortium. Prevalence and determinants of the precursor stages of heart failure: results from the population-based STAAB cohort study. European Journal of Preventive Cardiology. 28(9):924-934. (2021)
doi:10.1177/2047487320922636

Wittner, R.;Holub, P.;Müller, H.;Geiger, J.;Goble, C.;Soiland-Reyes, S.;Pireddu, L.;Frexia, F.;Mascia, C.;Fairweather, E.;Swedlow, J. R.;Moore, J.;Strambio, C.;Grunwald, D.;Nakae, H. ISO 23494: Biotechnology – Provenance Information Model for Biological Specimen And Data. In: Boris Glavic, Vanessa Braganholo, David Koop, eds. Provenance and Annotation of Data and Processes. Vol 12839. Lecture Notes in Computer Science. Springer International Publishing; 2021:222-225. 
doi:10.1007/978-3-030-80960-7_16

Bild, R.;Bialke, M.;Buckow, K.;Ganslandt, T.;Ihrig, K.;Jahns, R.;Merzweiler, A.;Roschka, S.;Schreiweis, B.;Staeubert, S.;Zenker, S.;Prasser, F. Towards a comprehensive and interoperable representation of consent-based data usage permissions in the German medical informatics initiative. BMC MEDICAL INFORMATICS AND DECISION MAKING. 20(1). (2020)
doi:10.1186/s12911-020-01138-6

Chifu, I.;Heinze, B.;Fuss, C. T.;Lang, K.;Kroiss, M.;Kircher, S.;Ronchi, C. L.;Altieri, B.;Schirbel, A.;Fassnacht, M.;Hahner, S. Impact of the Chemokine Receptors CXCR4 and CXCR7 on Clinical Outcome in Adrenocortical Carcinoma. Front Endocrinol. 11:597878. (2020) 
doi:10.3389/fendo.2020.597878

Eklund, N.;Andrianarisoa, N. H.;van Enckevort, E.;Anton, G.;Debucquoy, A.;Müller, H.;Zaharenko, L.;Engels, C.;Ebert, L.;Neumann, M.;Geeraert, J.;T’Joen, V.;Demski, H.;Caboux, É.;Proynova, R.;Parodi, B.;Mate, S.;van Iperen, E.;Merino-Martinez, R.;Quinlan, P. R.;Holub, P.;Silander, K. Extending the Minimum Information About BIobank Data Sharing Terminology to Describe Samples, Sample Donors, and Events. Biopreservation and Biobanking. Published online April 17, 2020. (2020)
doi:10.1089/bio.2019.0129

Frey, A.;Gassenmaier, T.;Hofmann, U.;Schmitt, D.;Fette, G.;Marx, A.;Herterich, S.;Boivin-Jahns, V.;Ertl, G.;Bley, T.;Frantz, S.;Jahns, R.;Stoerk, S. Coagulation factor XIII activity predicts left ventricular remodelling after acute myocardial infarction. ESC HEART FAILURE. 7(5):2354-2364. (2020)
doi:10.1002/ehf2.12774 

Perseil, I.;Sansone, S.-A.;McQuilton, P.;Dumontier, M.;Roos, M.;Bonino, L.;Wittner, R.;Holub, P.;Geiger, J. EOSC-Life FAIR Requirements Document. Published online March 2, 2020. doi:10.5281/ZENODO.3693883

Schollbach, J.;Kircher, S.;Wiegering, A.;Anger, F.;Rosenwald, A.;Germer, C.-T.;Löb, S. The local immune phenotype influences prognosis in patients with nodal-positive rectal cancer after neoadjuvant chemoradiation. Int J Colorectal Dis. 35(2):365-370. (2020)
doi:10.1007/s00384-019-03466-0

Woelfel, A.;Sattele, M.;Zechmeister, C.;Nikolaev, V. O.;Lohse, M. J.;Boege, F.;Jahns, R.;Boivin-Jahns, V. Unmasking features of the auto-epitope essential for β1-adrenoceptor activation by autoantibodies in chronic heart failure. ESC HEART FAILURE. 7(4):1830-1841. (2020)
doi:10.1002/ehf2.12747

Almanzar, G.;Schmalzing, M.;Klein, M.;Hilligardt, D.;Morris, P.;Höfner, K.;Hajj, N. E.;Kneitz, H.;Wild, V.;Rosenwald, A.;Benoit, S.;Hamm, H.;Tony, H.-P.;Haaf, T.;Goebeler, M.;Prelog, M. Memory CD4+ T cells lacking expression of CCR7 promote pro-inflammatory cytokine production in patients with diffuse cutaneous systemic sclerosis. European Journal of Dermatology. 29(5):468-476. (2019)
doi:10.1684/ejd.2019.3645

Appenzeller, S.;Gesierich, A.;Thiem, A.;Hufnagel, A.;Jessen, C.;Kneitz, H.;Regensburger, M.;Schmidt, C.;Zirkenbach, V.;Bischler, T.;Schilling, B.;Siedel, C.;Goebeler, M.;Houben, R.;Schrama, D.;Gehrig, A.;Rost, S.;Maurus, K.;Bargou, R.;Rosenwald, A.;Schartl, M.;Goebeler, M.;Meierjohann, S. The identification of patient‐specific mutations reveals dual pathway activation in most patients with melanoma and activated receptor tyrosine kinases in BRAF/NRAS wild‐type melanomas. Cancer. 125(4):586-600. (2019)
doi:10.1002/cncr.31843

Baber, R.;Hummel, M.;Jahns, R.;von Jagwitz-Biegnitz, M.;Kirsten, R.;Klingler, C.;Nussbeck, S. Y.;Specht, C. Position Statement from the German Biobank Alliance on the Cooperation Between Academic Biobanks and Industry Partners. Biopreservation and Biobanking. 17(4):372-374. (2019)
doi:10.1089/bio.2019.0042

Barrio, S.;Stühmer, T.;Da-Viá, M.;Barrio-Garcia, C.;Lehners, N.;Besse, A.;Cuenca, I.;Garitano-Trojaola, A.;Fink, S.;Leich, E.;Chatterjee, M.;Driessen, C.;Martinez-Lopez, J.;Rosenwald, A.;Beckmann, R.;Bargou, R. C.;Braggio, E.;Stewart, A. K.;Raab, M. S.;Einsele, H.;Kortüm, K. M. Spectrum and functional validation of PSMB5 mutations in multiple myeloma. Leukemia. 33(2):447-456. (2019) doi:10.1038/s41375-018-0216-8

Gensler, D.;Salinger, T.;Düring, M.;Lorenz, K.;Jahns, R.;Wech, T.;Frantz, S.;Ertl, G.;Jakob, P. M.;Nordbeck, P. Real‐time Triggered RAdial Single‐Shot Inversion recovery for arrhythmia‐insensitive myocardial T1 mapping: motion phantom validation and in vivo comparison. Magn Reson Med. 81(3):1714-1725. (2019)
doi:10.1002/mrm.27526

Gil-Cruz, C.;Perez-Shibayama, C.;De Martin, A.;Ronchi, F.;van der Borght, K.;Niederer, R.;Onder, L.;Lütge, M.;Novkovic, M.;Nindl, V.;Ramos, G.;Arnoldini, M.;Slack, E. M. C.;Boivin-Jahns, V.;Jahns, R.;Wyss, M.;Mooser, C.;Lambrecht, B. N.;Maeder, M. T.;Rickli, H.;Flatz, L.;Eriksson, U.;Geuking, M. B.;McCoy, K. D.;Ludewig, B. Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy. Science. 366(6467):881-886. (2019) 
doi:10.1126/science.aav3487

Hartmann, S.;Plütschow, A.;Mottok, A.;Bernd, H.;Feller, A. C.;Ott, G.;Cogliatti, S.;Fend, F.;Quintanilla‐Martinez, L.;Stein, H.;Klapper, W.;Möller, P.;Rosenwald, A.;Engert, A.;Hansmann, M.;Eichenauer, D. A. The time to relapse correlates with the histopathological growth pattern in nodular lymphocyte predominant Hodgkin lymphoma. Am J Hematol. 94(11):1208-1213. (2019) 
doi:10.1002/ajh.25607

Jahns, R.;Geiger, J.;Schlünder, I.;Strech, D.;Brumhard, M.;von Kielmansegg, S. G. Broad donor consent for human biobanks in Germany and Europe: a strategy to facilitate cross-border sharing and exchange of human biological materials and related data. J Lab Med. 43(6):291-299. (2019)
doi:10.1515/labmed-2017-0064

Kircher, S.;Stolzenburg, A.;Kortüm, K. M.;Kircher, M.;Da Via, M.;Samnick, S.;Buck, A. K.;Einsele, H.;Rosenwald, A.;Lapa, C. Hexokinase-2 Expression in 11 C-Methionine–Positive, 18 F-FDG–Negative Multiple Myeloma. J Nucl Med. 60(3):348-352. (2019)
doi:10.2967/jnumed.118.217539

Lapa, C.;Lückerath, K.;Kircher, S.;Hänscheid, H.;Grigoleit, G. U.;Rosenwald, A.;Stolzenburg, A.;Kropf, S.;Einsele, H.;Wester, H.-J.;Buck, A. K.;Kortüm, K. M.;Schirbel, A. Potential influence of concomitant chemotherapy on CXCR4 expression in receptor directed endoradiotherapy. Br J Haematol. 184(3):440-443. (2019)
doi:10.1111/bjh.15096

Longerich, T.;Endris, V.;Neumann, O.;Rempel, E.;Kirchner, M.;Abadi, Z.;Uhrig, S.;Kriegsmann, M.;Weiss, K. H.;Breuhahn, K.;Mehrabi, A.;Weber, T. F.;Wilkens, L.;Straub, B. K.;Rosenwald, A.;Schulze, F.;Brors, B.;Froehling, S.;Pellegrino, R.;Budczies, J.;Schirmacher, P.;Stenzinger, A. RSPO2 gene rearrangement: a powerful driver of β-catenin activation in liver tumours. Gut. 68(7):1287-1296. (2019)
doi:10.1136/gutjnl-2018-317632

Morbach, C.;Gelbrich, G.;Tiffe, T.;Eichner, F.;Wagner, M.;Heuschmann, P. U.;Störk, S.;Frantz, S.;Maack, C.;Ertl, G.;Fassnacht, M.;Wanner, C.;Leyh, R.;Volkmann, J.;Deckert, J.;Faller, H.;Jahns, R. Variations in cardiovascular risk factors in people with and without migration background in Germany – Results from the STAAB cohort study. International Journal of Cardiology. 286:186-189. (2019) 
doi:10.1016/j.ijcard.2018.10.098

Rauert‐Wunderlich, H.;Mottok, A.;Scott, D. W.;Rimsza, L. M.;Ott, G.;Klapper, W.;Unterhalt, M.;Kluin‐Nelemans, H. C.;Hermine, O.;Hartmann, S.;Thorns, C.;Rymkiewicz, G.;Holte, H.;Dreyling, M.;Hoster, E.;Rosenwald, A. Validation of the MCL 35 gene expression proliferation assay in randomized trials of the European Mantle Cell Lymphoma Network. Br J Haematol. 184(4):616-624. (2019)
doi:10.1111/bjh.15519

Schmidt, S.;Gay, D.;Uthe, F. W.;Denk, S.;Paauwe, M.;Matthes, N.;Diefenbacher, M. E.;Bryson, S.;Warrander, F. C.;Erhard, F.;Ade, C. P.;Baluapuri, A.;Walz, S.;Jackstadt, R.;Ford, C.;Vlachogiannis, G.;Valeri, N.;Otto, C.;Schülein-Völk, C.;Maurus, K.;Schmitz, W.;Knight, J. R. P.;Wolf, E.;Strathdee, D.;Schulze, A.;Germer, C.-T.;Rosenwald, A.;Sansom, O. J.;Eilers, M.;Wiegering, A. A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer. Nat Cell Biol. 21(11):1413-1424. (2019)
doi:10.1038/s41556-019-0408-0

Schollbach, J.;Kircher, S.;Wiegering, A.;Seyfried, F.;Klein, I.;Rosenwald, A.;Germer, C.-T.;Löb, S. Prognostic value of tumour-infiltrating CD8+ lymphocytes in rectal cancer after neoadjuvant chemoradiation: is indoleamine-2,3-dioxygenase (IDO1) a friend or foe? Cancer Immunol Immunother. 68(4):563-575. (2019)
doi:10.1007/s00262-019-02306-y

Schwarz, N.;Knutti, N.;Rose, M.;Neugebauer, S.;Geiger, J.;Jahns, R.;Klopp, N.;Illig, T.;Mathay, C.;Betsou, F.;Scherag, A.;Kiehntopf, M. Quality Assessment of the Preanalytical Workflow in Liquid Biobanking: Taurine as a Serum-Specific Quality Indicator for Preanalytical Process Variations. Biopreservation and Biobanking. 17(5):458-467. (2019)
doi:10.1089/bio.2019.0004

Sibon, D.;Nguyen, D.-P.;Schmitz, N.;Suzuki, R.;Feldman, A. L.;Gressin, R.;Lamant, L.;Weisenburger, D. D.;Rosenwald, A.;Nakamura, S.;Ziepert, M.;Maurer, M. J.;Bast, M.;Armitage, J. O.;Vose, J. M.;Tilly, H.;Jais, J.-P.;Savage, K. J. ALK-positive anaplastic large-cell lymphoma in adults: an individual patient data pooled analysis of 263 patients. Haematologica. 104(12):e562-e565. (2019) 
doi:10.3324/haematol.2018.213512 

Stein, R. G.;Ebert, S.;Schlahsa, L.;Scholz, C. J.;Braun, M.;Hauck, P.;Horn, E.;Monoranu, C.-M.;Thiemann, V. J.;Wustrow, M. P.;Häusler, S. F.;Montalbán del Barrio, I.;Stüber, T. N.;Wölfl, M.;Dietl, J.;Rosenwald, A.;Diessner, J. E.;Wöckel, A.;Wischhusen, J. Cognate Nonlytic Interactions between CD8 + T Cells and Breast Cancer Cells Induce Cancer Stem Cell–like Properties. Cancer Res. 79(7):1507-1519. (2019) 
doi:10.1158/0008-5472.CAN-18-0387

Wallaschek, N.;Niklas, C.;Pompaiah, M.;Wiegering, A.;Germer, C.-T.;Kircher, S.;Brändlein, S.;Maurus, K.;Rosenwald, A.;Yan, H. H. N.;Leung, S. Y.;Bartfeld, S. Establishing Pure Cancer Organoid Cultures: Identification, Selection and Verification of Cancer Phenotypes and Genotypes. Journal of Molecular Biology. 431(15):2884-2893. (2019)
doi:10.1016/j.jmb.2019.05.031

Werner, R. A.;Wakabayashi, H.;Bauer, J.;Schütz, C.;Zechmeister, C.;Hayakawa, N.;Javadi, M. S.;Lapa, C.;Jahns, R.;Ergün, S.;Jahns, V.;Higuchi, T. Longitudinal 18F-FDG PET imaging in a rat model of autoimmune myocarditis. European Heart Journal - Cardiovascular Imaging. 20(4):467-474. (2019)
doi:10.1093/ehjci/jey119

Betsou, F.;Bilbao, R.;Case, J.;Chuaqui, R.;Clements, J. A.;De Souza, Y.;De Wilde, A.;Geiger, J.;Grizzle, W.;Guadagni, F.;Gunter, E.;Heil, S.;Kiehntopf, M.;Koppandi, I.;Lehmann, S.;Linsen, L.;Mackenzie-Dodds, J.;Aguilar Quesada, R.;Tebbakha, R.;Selander, T.;Shea, K.;Sobel, M.;Somiari, S.;Spyropoulos, D.;Stone, M.;Tybring, G.;Valyi-Nagy, K.;Wadhwa, L. Standard PREanalytical Code version 3.0. Biopreservation and Biobanking. 16(1):9-12. (2018)
doi:10.1089/bio.2017.0109

Boege, F. Relevant effects of beta sub 1 sub -adrenoceptor autoantibodies in chronic heart failure. Front Biosci. 23(11):2146-2156. (2018)
doi:10.2741/4695

Boivin-Jahns, V.;Jahns, R. GPCR-autoantibodies in chronic heart failure. Front Biosci (Landmark Ed). 23(11):2065-2081. (2018)
doi:10.2741/4690

Boivin-Jahns, V.;Jahns, R.;Boege, F. Relevant effects of beta1-adrenoceptor autoantibodies in chronic heart failure. Front Biosci (Landmark Ed). 23(11):2146-2156. (2018)
doi:10.2741/4695

Boivin-Jahns, V.;Uhland, K.;Holthoff, H.-P.;Beyersdorf, N.;Kocoski, V.;Kerkau, T.;Münch, G.;Lohse, M. J.;Ungerer, M.;Jahns, R. Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure. Esaki M. Shankar, ed. PLoS ONE. 13(8):e0201160. (2018)
doi:10.1371/journal.pone.0201160

Boivin-Jahns, V.;Zechmeister, C.;Schuetz, C.;Beyersdorf, N.;Stoerk, S.;Jahns, R. First results of the prospective ETiCS-study: acute (microbial-associated) inflammation rather than (infarction-associated) myocardial ischemia triggers the development of cardiac GPCR autoantibodies. Advances in RAB Research. 1(1):in RAB Research-2018. (2018)
doi:10.18416/RAB.2018.1809021

Geiger, J.;Both, S.;Kircher, S.;Neumann, M.;Rosenwald, A.;Jahns, R. Hospital-integrated Biobanking as a Service – The Interdisciplinary Bank of Biomaterials and Data Wuerzburg (ibdw). Open Journal of Bioresources. 5:6. (2018)
doi:10.5334/ojb.38

Horn, H.;Kohler, C.;Witzig, R.;Kreuz, M.;Leich, E.;Klapper, W.;Hummel, M.;Loeffler, M.;Trümper, L.;Spang, R.;Rosenwald, A.;Ott, G.;for the Molecular Mechanisms in Malignant Lymphomas (MMML) Network Project. Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2. Haematologica. 103(7):1182-1190.(2018) 
doi:10.3324/haematol.2017.181024

Jahns, R.;Schirmacher, P. Ethik und Rechtslage von humanen Biobanken. Pathologe. 39(5):445-448. (2018)
doi:10.1007/s00292-018-0472-4

Langhof, H.;Kahrass, H.;Illig, T.;Jahns, R.;Strech, D. Current practices for access, compensation, and prioritization in biobanks. Results from an interview study. Eur J Hum Genet. 26(11):1572-1581.(2018) doi:10.1038/s41431-018-0228-x

Laufs, V.;Altieri, B.;Sbiera, S.;Kircher, S.;Steinhauer, S.;Beuschlein, F.;Quinkler, M.;Willenberg, H. S.;Rosenwald, A.;Fassnacht, M.;Ronchi, C. L. ERCC1 as predictive biomarker to platinum-based chemotherapy in adrenocortical carcinomas. European Journal of Endocrinology. 178(2):181-188. (2018) 
doi:10.1530/EJE-17-0788

Lippert, J.;Appenzeller, S.;Liang, R.;Sbiera, S.;Kircher, S.;Altieri, B.;Nanda, I.;Weigand, I.;Gehrig, A.;Steinhauer, S.;Riemens, R. J. M.;Rosenwald, A.;Müller, C. R.;Kroiss, M.;Rost, S.;Fassnacht, M.;Ronchi, C. L. Targeted Molecular Analysis in Adrenocortical Carcinomas: A Strategy Toward Improved Personalized Prognostication. The Journal of Clinical Endocrinology & Metabolism. 103(12):4511-4523. (2018) doi:10.1210/jc.2018-01348

Mottok, A.;Wright, G.;Rosenwald, A.;Ott, G.;Ramsower, C.;Campo, E.;Braziel, R. M.;Delabie, J.;Weisenburger, D. D.;Song, J. Y.;Chan, W. C.;Cook, J. R.;Fu, K.;Greiner, T.;Smeland, E.;Holte, H.;Savage, K. J.;Glinsmann-Gibson, B. J.;Gascoyne, R. D.;Staudt, L. M.;Jaffe, E. S.;Connors, J. M.;Scott, D. W.;Steidl, C.;Rimsza, L. M. Molecular classification of primary mediastinal large B-cell lymphoma using routinely available tissue specimens. Blood. 132(22):2401-2405. (2018) 
doi:10.1182/blood-2018-05-851154

Reinke, S.;Richter, J.;Fend, F.;Feller, A.;Hansmann, M.-L.;Hüttl, K.;Oschlies, I.;Ott, G.;Möller, P.;Rosenwald, A.;Stein, H.;Altenbuchinger, M.;Spang, R.;Klapper, W. Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma—a feasibility study using full slide staining. Virchows Arch. 473(3):341-349. (2018) 
doi:10.1007/s00428-018-2367-4 

Rukoyatkina, N.;Shpakova, V.;Panteleev, M.;Kharazova, A.;Gambaryan, S.;Geiger, J. Multifaceted effects of arachidonic acid and interaction with cyclic nucleotides in human platelets. Thrombosis Research. 171:22-30. (2018) 
doi:10.1016/j.thromres.2018.09.047

Solimando, A. G.;Brandl, A.;Mattenheimer, K.;Graf, C.;Ritz, M.;Ruckdeschel, A.;Stühmer, T.;Mokhtari, Z.;Rudelius, M.;Dotterweich, J.;Bittrich, M.;Desantis, V.;Ebert, R.;Trerotoli, P.;Frassanito, M. A.;Rosenwald, A.;Vacca, A.;Einsele, H.;Jakob, F.;Beilhack, A. JAM-A as a prognostic factor and new therapeutic target in multiple myeloma. Leukemia. 32(3):736-743. (2018) 
doi:10.1038/leu.2017.287

Zamò, A.;Pischimarov, J.;Schlesner, M.;Rosenstiel, P.;Bomben, R.;Horn, H.;Grieb, T.;Nedeva, T.;López, C.;Haake, A.;Richter, J.;Trümper, L.;Lawerenz, C.;Klapper, W.;Möller, P.;Hummel, M.;Lenze, D.;Szczepanowski, M.;Flossbach, L.;Schreder, M.;Gattei, V.;Ott, G.;Siebert, R.;Rosenwald, A.;Leich, E. Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing. Leukemia. 32(3):685-693. (2018) 
doi:10.1038/leu.2017.270

Beck, F.;Geiger, J.;Gambaryan, S.;Solari, F. A.;Dell’Aica, M.;Loroch, S.;Mattheij, N. J.;Mindukshev, I.;Poetz, O.;Jurk, K.;Burkhart, J. M.;Fufezan, C.;Heemskerk, J. W. M.;Walter, U.;Zahedi, R. P.;Sickmann, A. Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition. Blood. 129(2):E1-E12. (2017)
doi:10.1182/blood-2016-05-714048

Boege, F.;Westenfeld, R.;Jahns, R. β 1 AAb Determined by Peptide ELISA. Journal of the American College of Cardiology. 70(6):807-808. (2017)
doi:10.1016/j.jacc.2017.03.617

Bouska, A.;Bi, C.;Lone, W.;Zhang, W.;Kedwaii, A.;Heavican, T.;Lachel, C. M.;Yu, J.;Ferro, R.;Eldorghamy, N.;Greiner, T. C.;Vose, J.;Weisenburger, D. D.;Gascoyne, R. D.;Rosenwald, A.;Ott, G.;Campo, E.;Rimsza, L. M.;Jaffe, E. S.;Braziel, R. M.;Siebert, R.;Miles, R. R.;Dave, S.;Reddy, A.;Delabie, J.;Staudt, L. M.;Song, J. Y.;McKeithan, T. W.;Fu, K.;Green, M.;Chan, W. C.;Iqbal, J. Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets. Blood. 130(16):1819-1831. (2017)
doi:10.1182/blood-2017-02-767335

Frings, V.;Roth, S.;Riedmiller, A.;Schäfer, K.;Goebeler, M.;Rosenwald, A.;Geissinger, E.;Wobser, M. Primary Cutaneous T-cell Lymphoma with Aberrant Expression of CD20. Acta Derm Venerol. 97(4):534-536.(2017) 
doi:10.2340/00015555-2576

de Leval, L.;Copie-Bergman, C.;Rosenwald, A.;Rimsza, L.;Pittaluga, S.;Bisig, B.;Dirnhofer, S.;Facchetti, F.;Pileri, S.;Fend, F.;Wotherspoon, A. B-cell lymphomas with discordance between pathological features and clinical behavior. Virchows Arch. 471(4):439-451. (2017)
doi:10.1007/s00428-017-2152-9

Ritter, J.;Zimmermann, K.;Jöhrens, K.;Mende, S.;Seegebarth, A.;Siegmund, B.;Hennig, S.;Todorova, K.;Rosenwald, A.;Daum, S.;Hummel, M.;Schumann, M. T-cell repertoires in refractory coeliac disease. Gut. Published online February 10, 2017:gutjnl-2016-311816. (2017)
doi:10.1136/gutjnl-2016-311816

Bornholz, B.;Benninghaus, T.;Reinke, Y.;Felix, S. B.;Roggenbuck, D.;Jahns-Boivin, V.;Jahns, R.;Boege, F. A standardised FACS assay based on native, receptor transfected cells for the clinical diagnosis and monitoring of β1-adrenergic receptor autoantibodies in human heart disease. CLINICAL CHEMISTRY AND LABORATORY MEDICINE. 54(4):683-691. (2016)
doi:10.1515/cclm-2015-0603

Bornholz, B.;Hanzen, B.;Reinke, Y.;Felix, S. B.;Jahns, R.;Schimke, I.;Wallukat, G.;Boege, F. Detection of DCM-associated beta(1)-adrenergic receptor autoantibodies requires functional readouts or native human beta(1)-receptors as targets. International Journal of Cardiology. 202:728-730. (2016)
doi:10.1016/j.ijcard.2015.10.068

Jahns, R. Establishing and operating a human biobank. Ethical aspects. Bundesgesundheitsblatt-Gesund. 59(3):311-316. (2016)
doi:10.1007/s00103-015-2292-5

Maya, Y.;Werner, R. A.;Schuetz, C.;Wakabayashi, H.;Samnick, S.;Lapa, C.;Zechmeister, C.;Jahns, R.;Jahns, V.;Higuchi, T. C-11-Methionine PET of Myocardial Inflammation in a Rat Model of Experimental Autoimmune Myocarditis. Journal of Nuclear Medicine. 57(12):1985-1990. (2016)
doi:10.2967/jnumed.116.174045

Nickerson, D.;Atalag, K.;de Bono, B.;Geiger, J.;Goble, C.;Hollmann, S.;Lonien, J.;Müller, W.;Regierer, B.;Stanford, N. J.;Golebiewski, M.;Hunter, P. The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable. Interface Focus. 6(2):20150103. (2016)
doi:10.1098/rsfs.2015.0103

Strech, D.;Bein, S.;Brumhard, M.;Eisenmenger, W.;Glinicke, C.;Herbst, T.;Jahns, R.;von Kielmansegg, S.;Schmidt, G.;Taupitz, J.;Tröger, H. D. A template for broad consent in biobank research. Results and explanation of an evidence and consensus-based development process. European Journal of Medical Genetics. 59(6-7):295-309. (2016)
doi:10.1016/j.ejmg.2016.04.002

Jahns, R.;Boege, F. Questionable Validity of Peptide-Based ELISA Strategies in the Diagnostics of Cardiopathogenic Autoantibodies That Activate G-Protein-Coupled Receptors. Cardiology. 131(3):149-150. doi:10.1159/000376546. (2015)

Lapa, C.;Reiter, T.;Li, X.;Werner, R. A.;Samnick, S.;Jahns, R.;Buck, A. K.;Ertl, G.;Bauer, W. R. Imaging of myocardial inflammation with somatostatin receptor based PET/CT - A comparison to cardiac MRI. International Journal of Cardiology. 194:44-49. doi:10.1016/j.ijcard.2015.05.073. (2015)

Bornholz, B.;Roggenbuck, D.;Jahns, R.;Boege, F. Diagnostic and therapeutic aspects of beta(1)-adrenergic receptor autoantibodies in human heart disease. Autoimmunity Reviews. 13(9):954-962. doi:10.1016/j.autrev.2014.08.021. (2014)

Geiger, J.;Burkhart, J. M.;Gambaryan, S.;Walter, U.;Sickmann, A.;Zahedi, R. P. Platelet transcriptome and proteome: relation rather than correlation Response. Blood. 121(26):5257-5258. doi:10.1182/blood-2013-04-493403. (2013)

Hubertus, K.;Mischnik, M.;Timmer, J.;Herterich, S.;Mark, R.;Moulard, M.;Walter, U.;Geiger, J. Reciprocal regulation of human platelet function by endogenous prostanoids and through multiple prostanoid receptors. European Journal of Pharmacology. 740:15-27. doi:10.1016/j.ejphar.2014.06.030. (2014)

Geiger, J.;Burkhart, J. M.;Gambaryan, S.;Walter, U.;Sickmann, A.;Zahedi, R. P. Platelet transcriptome and proteome: relation rather than correlation Response. Blood. 121(26):5257-5258. doi:10.1182/blood-2013-04-493403. (2013)

Boivin-Jahns, V.;Schlipp, A.;Hartmann, S.;Panjwani, P.;Klingel, K.;Lohse, M. J.;Ertl, G.;Jahns, R. Antibodies to cardiac receptors. Herz. 37(8):843-848. doi:10.1007/s00059-012-3699-5. (2012)

Jahns, R.; Neumann, M.;Geiger, J.; Kößler, J. ; Störk, S.; Walter U. Humane Biomaterialbanken Potenzial und Herausforderung. Bayer Ärzteblatt. 6:356-359. (2011)