Die Publikationen des Lehrstuhls TERM

Der Lehrstuhl TERM veröffentlicht regelmäßig Forschungsergebnisse in nationalen und internationalen Veröffentlichungsforen. Im Folgenden ist eine Auswahl der Publikationen der vergangenen Jahre aufgelistet.


Borova, S., et al. (2022).
"A Transient Initiator for Polypeptoids Postpolymerization alpha-Functionalization via Activation of a Thioester Group."
Macromolecular Chemistry and Physics 223(3).

Fahmy-Garcia, S., et al. (2022).
"Bmp-9 Variant with Increased Ecm-Binding Capability Displays Superior Bone-Forming Capacity to Those of Native Bmp-2 and Bmp-9."
Tissue Engineering Part A 28: S454-S455.

Geiger, N., et al. (2022).
"Acetylsalicylic Acid and Salicylic Acid Inhibit SARS-CoV-2 Replication in Precision-Cut Lung Slices."
Vaccines 10(10).

Herbert, S. L., et al. (2022).
"Establishment of the SIS scaffold-based 3D model of human peritoneum for studying the dissemination of ovarian cancer J"
Tissue Eng. 2022 Mar

Kozjak-Pavlovic, V., et al. (2022).
"Editorial: 3D tissue models in infection research."
Frontiers in Cellular and Infection Microbiology 12.    

Leikeim, A., et al. (2022).
"A preclinical model of cutaneous melanoma based on reconstructed human epidermis."
Scientific Reports 12(1).

Menzel-Severing, J., et al. (2022).
"Regenerative medicine for the corneal epithelium Cell therapy from bench to bedside."
Ophthalmologie 119(9): 891-901.

Peindl, M., et al. (2022).
"EMT, Stemness, and Drug Resistance in Biological Context: A 3D Tumor Tissue/In Silico Platform for Analysis of Combinatorial Treatment in NSCLC with Aggressive KRAS-Biomarker Signatures."
Cancers 14(9).

Rohde, F., et al. (2022).
"In-situ tear fluid dissolving nanofibers enable prolonged viscosity-enhanced dual drug delivery to the eye."
International Journal of Pharmaceutics 616.

Sivarajan, R., et al. (2022).
"A defined anthocyanin mixture sourced from bilberry and black currant inhibits Measles virus and various herpesviruses."
Bmc Complementary Medicine and Therapies 22(1).

Siverino, C., et al. (2022).
"Site-Directed Immobilization of an Engineered Bone Morphogenetic Protein 2 (BMP2) Variant to Collagen-Based Microspheres Induces Bone Formation In Vivo."
International Journal of Molecular Sciences 23(7).

Tuca, A. C., et al. (2022).
"Orchestrating the Dermal/Epidermal Tissue Ratio during Wound Healing by Controlling the Moisture Content."
Biomedicines 10(6).

Wallenwein, C. M., et al. (2022).
"Pharmaceutical Development of Nanostructured Vesicular Hydrogel Formulations of Rifampicin for Wound Healing."
International Journal of Molecular Sciences 23(24).

Weigel, T., et al. (2022).
"Fully Synthetic 3D Fibrous Scaffolds for Stromal Tissues-Replacement of Animal-Derived Scaffold Materials Demonstrated by Multilayered Skin."
Advanced Materials 34(10).

Wussmann, M., et al. (2022).
"In Model, In Vitro and In Vivo Killing Efficacy of Antitumor Peptide RDP22 on MUG-Mel2, a Patient Derived Cell Line of an Aggressive Melanoma Metastasis."
Biomedicines 10(11).


Bianchi M, Sivarajan R, Walles T, Hackenberg S, Steinke M (2021)
Susceptibility of primary human airway epithelial cells to Bordetella pertussis adenylate cyclase toxin in two- and three-dimensional culture conditions.
Innate Immun. 2021 Jan;27(1):89-98. doi: 10.1177/1753425920979354. Epub 2020 Dec 14.

Delacher M, Simon M, Sanderink L, Hotz-Wagenblatt A, Wuttke M, Schambeck K, Schmidleithner L, Bittner S, Pant A, Ritter U, Hehlgans T, Riegel D, Schneider V, Groeber-Becker FK, Eigenberger A, Gebhard C, Strieder N, Fischer A, Rehli M, Hoffmann P, Edinger M, Strowig T, Huehn J, Schmidl C, Werner JM, Prantl L, Brors B, Imbusch CD, Feuerer M (2021)
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells.
Immunity. 2021 A
pr 13;54(4):702-720.e17. doi: 10.1016/j.immuni.2021.03.007. Epub 2021 Mar 30.

Griffoni C, Neidhart B, Yang K, Groeber-Becker F, Maniura-Weber K, Dandekar T, Walles H, Rottmar M (2021)
In vitro skin culture media influence the viability and inflammatory response of primary macrophages.
Sci Rep. 2021 Mar 29;11(1):7070. doi: 10.1038/s41598-021-86486-7.

Haeusner S, Herbst L, Bittorf P, Schwarz T, Henze C, Mauermann M, Ochs J, Schmitt R, Blache U, Wixmerten A, Miot S, Martin I, Pullig O (2021)
From Single Batch to Mass Production-Automated Platform Design Concept for a Phase II Clinical Trial Tissue Engineered Cartilage Product.
Front Med (Lausanne). 2021 Aug 13;8:712917. doi: 10.3389/fmed.2021.712917. eCollection 2021.

Heydarian M, Schweinlin M, Schwarz T, Rawal R, Walles H, Metzger M, Rudel T, Kozjak-Pavlovic V (2021) 
Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity. 
J Tissue Eng. 2021 Jan 28;12:2041731420988802. (IF 7.8)

Kessie DK, Lodes N, Oberwinkler H, Goldman WE, Walles T, Steinke M, Gross R (2021)
Activity of Tracheal Cytotoxin of Bordetella pertussis in a Human Tracheobronchial 3D Tissue Model.
Front Cell Infect Microbiol. 2021 Jan 19;10:614994. doi: 10.3389/fcimb.2020.614994. eCollection 2020.

Ngamsri KC, Fabian F, Fuhr A, Gamper-Tsigaras J, Straub A, Fecher D, Steinke M, Walles H, Reutershan J, Konrad FM (2021)
Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling.
Anesthesiology. 2021 Jul 1;135(1):136-150. doi: 10.1097/ALN.0000000000003788.

Ramírez-Rodríguez GB, Pereira AR, Herrmann M, Hansmann J, Delgado-López JM, Sprio S, Tampieri A, Sandri M (2021)
Biomimetic Mineralization Promotes Viability and Differentiation of Human Mesenchymal Stem Cells in a Perfusion Bioreactor.
Int J Mol Sci. 2021 Feb 1;22(3):1447. doi: 10.3390/ijms22031447.

Schneider, V., et al. (2021).
"A 3D In Vitro Model for Burn Wounds: Monitoring of Regeneration on the Epidermal Level."
Biomedicines 9(9). doi: 10.3390/biomedicines9091153

Trujillo-Viera J, El-Merahbi R, Schmidt V, Karwen T, Loza-Valdes A, Strohmeyer A, Reuter S, Noh M, Wit M, Hawro I, Mocek S, Fey C, Mayer AE, Löffler MC, Wilhelmi I, Metzger M, Ishikawa E, Yamasaki S, Rau M, Geier A, Hankir M, Seyfried F, Klingenspor M, Sumara G (2021)
Protein Kinase D2 drives chylomicron-mediated lipid transport in the intestine and promotes obesity. 
EMBO Mol Med. 2021 May 7;13(5):e13548. (IF 10.3)

Weigel T, Brennecke J, Hansmann J (2021)
Improvement of the Electronic-Neuronal Interface by Natural Deposition of ECM.
Materials (Basel). 2021 Mar 12;14(6):1378. doi: 10.3390/ma14061378.

Yamada S, Yassin MA, Schwarz T, Hansmann J, Mustafa K (2021)
Induction of osteogenic differentiation of bone marrow stromal cells on 3D polyester-based scaffolds solely by subphysiological fluidic stimulation in a laminar flow bioreactor.
J Tissue Eng. 2021 Jun 24;12:20417314211019375. doi: 10.1177/20417314211019375. eCollection 2021 Jan-Dec.

Yamada S, Yassin MA, Weigel T, Schmitz T, Hansmann J, Mustafa K (2021)
Surface activation with oxygen plasma promotes osteogenesis with enhanced extracellular matrix formation in three-dimensional microporous scaffolds.
J Biomed Mater Res A. 2021 Sep;109(9):1560-1574. doi: 10.1002/jbm.a.37151. Epub 2021 Mar 5.

Zimniak M, Kirschner L, Hilpert H, Geiger N, Danov O, Oberwinkler H, Steinke M, Sewald K, Seibel J, Bodem J (2021)
The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue.
Sci Rep. 2021 Mar 15;11(1):5890. doi: 10.1038/s41598-021-85049-0.


Alzheimer M, Sarah L, Svensson SL, König F, Schweinlin M, Metzger M, Walles H, Sharma CM (2020)
A Three-Dimensional Intestinal Tissue Model Reveals Factors and Small Regulatory RNAs Important for Colonization With Campylobacter Jejuni.
PLoS Pathog 2020 Feb 18;16(2):e1008304. doi: 10.1371/journal.ppat.1008304.

Berger C, Bjørlykke Y, Hahn L, Mühlemann M, Kress S, Walles H, Luxenhofer R, Ræder H, Metzger M, Zdzieblo D (2020)
Matrix decoded - A pancreatic extracellular matrix with organ specific cues guiding human iPSC differentiation.
Biomaterials 244:119766. 2020. doi: 10.1016/j.biomaterials.2020.119766.

Burghartz M, Taeger J, Metzger M, Scherzad M, Gehrke T, Ickrath P, Kolb E, Kleinsasser N, Hagen R, Hackenberg S (2020)
Investigation of Cellular Function and DNA Integrity during 2D in vitro Culture of Human Salivary Gland Epithelial Cells. 
Cells Tissues Organs 2020, 208, 66-75. (IF 2.0)

Berger C, Zdzieblo D (2020)
Glucose Transporters in Pancreatic Islets.
Pflügers Archiv - European Journal of Physiology. 2020. doi: 10.1007/s00424-020-02383-4.

Däullary T, Fey C, Berger C, Metzger M, Zdzieblo D (2020)
Bioartificial gut – current state of small intestinal tissue engineering.
Biomaterials for Organ and Tissue Regeneration, New Technologies and Future Prospects. 2020. ISBN: 978-0-08-102906-0. doi: 10.1016/C2018-0-02069-1.

Fey C, Betz J, Rosenbaum C, Kralisch D, Vielreicher M, Friedrich O, Metzger M, Zdzieblo D (2020)
Bacterial nanocellulose as novel carrier for intestinal epithelial cells in drug delivery studies.
Mater Sci Eng C Mater Biol Appl. 109:110613. 2020. doi: 10.1016/j.msec.2019.110613.

Hoffmann J, Fayez S, Hofmann M, Scheiner M, Maher P, Maurice T, . . . Appelt-Menzel A. (2020)
Sterubin: enantioresolution and configurational stability, enantiomeric purity in nature, and neuroprotective activity in vitro and in vivo.
Chemistry. doi:10.1002/chem.202001264.

Li P, Lee HR, Chandel S, Lotz C, Groeber-Becker FK, Dembski S, Ossikovski R, Ma H, Novikova T (2020)
Analysis of tissue microstructure with Mueller microscopy: logarithmic decomposition and Monte Carlo modeling. J Biomed Opt. 2020 Jan;25(1):1-11. doi: 10.1117/1.JBO.25.1.015002.

Lodes N, Seidensticker K, Perniss A, Nietzer S, Oberwinkler H, May T, Walles T, Hebestreit H, Hackenberg S, Steinke M (2020)
Investigation on Ciliary Functionality of Different Airway Epithelial Cell Lines in Three-Dimensional Cell Culture.
Tissue Eng Part A. 2020 Apr;26(7-8):432-440. doi: 10.1089/ten.TEA.2019.0188.

Lubtow MM, Oerter S, Quader S, Jeanclos E, Cubukova A, Krafft M, Luxenhofer R (2020)
In vitro blood-brain-barrier permeability and cytotoxicity of atorvastatin-loaded nanoformulation against glioblastoma in 2D and 3D models.
Mol Pharm. doi:10.1021/acs.molpharmaceut.9b01117.

Meir M, Burkard N, Ungewiß H, Diefenbacher M, Flemming S, Kannapin F, Germer CT, Schweinlin M, Metzger M, Waschke J, Schlegel N (2020)
Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease.
J Clin Invest. 2019 Jun 17;129(7):2824-2840. doi: 10.1172/JCI120261.

Meir M, Salm J, Fey C, Schweinlin M, Kollmann C, Kannapin F, Germer CT, Waschke J, Beck C, Burkard N, Metzger M, Schlegel N (2020)
Enteroids generated from patients with severe inflammation in Crohn's disease maintain alterations of junctional proteins.
J Crohns Colitis. 2020 Apr 28:jjaa085. doi: 10.1093/ecco-jcc/jjaa085.

Rackwitz L, Pullig O, Nöth U (2020). Prevention of Osteoarthritis and Future Strategies for Osteoarthritis Therapy – an Orthopaedic and Trauma-Surgical Perspective. Akt Rheumatol 2020; 45(01): 96-105, doi: 10.1055/a-1036-4100.

Schulte LN, Schweinlin M, Westermann AJ, Janga H, Santos SC, Appenzeller S, Walles H, Vogel J, Metzger M (2020)
An Advanced Human Intestinal Coculture Model Reveals Compartmentalized Host and Pathogen Strategies During Salmonella Infection.
mBio 2020 Feb 18;11(1):e03348-19. doi: 10.1128/mBio.03348-19.

Schwedhelm I, Zdzieblo D, Appelt-Menzel A, Berger C, Schmitz T, Schuldt B, Franke A, Müller FJ, Pless O, Schwarz T, Wiedemann P, Walles H, Hansmann J (2020)
Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors.
Sci Rep 23;9(1):12297. 2019. doi: 10.1038/s41598-019-48814-w.

Stüber T, Monjezi R, Wallstabe L, Kühnemundt J, Nietzer SL, Dandekar G, Wöckel A, Einsele H, Wischhusen J, Hudecek M (2020)
Inhibition of TGF-β-receptor signaling augments the antitumor function of ROR1-specific CAR T-cells against triple-negative breast cancer.
J Immunother Cancer. 2020 Apr;8(1):e000676. doi: 10.1136/jitc-2020-000676.

Wallstabe J, Bussemer L, Groeber-Becker F, Freund L, Alb M, Dragan M, Waaga-Gasser AM, Jakubietz R, Kneitz H, Rosenwald A, Rebhan S, Walles H, Mielke S (2020)
Inflammation-induced tissue damage mimicking GvHD in human skin models as test-platform for immunotherapeutics.
ALTEX. 2020 Apr 14. doi: 10.14573/altex.1907181.


Belka J, Nickel J, Kurth DG (2019)
Growth on Metallo-Supramolecular Coordination Polyelectrolyte (MEPE) Stimulates Osteogenic Differentiation of Human Osteosarcoma Cells (MG63) and Human Bone Marrow Derived Mesenchymal Stem Cells.
Polymers (Basel), 11(7).

Boepple K, Dong M, Winkler B, Janssen N, Kleih M, Essmann F, Walles H, Ott G, Schwab M, Aulitzky WE (2019)
An advanced non-animal model for cultivation and pharmacological perturbation of human tumor tissue.
N-S Arch Pharmacol, 392:S79-S79.

Bode KJ, Mueller S, Schweinlin M, Metzger M, Brunner T (2019)
A fast and simple fluorometric method to detect cell death in 3D intestinal organoids. Biotechniques, 67(1):23-28.

Colunga T, Hayworth M, Kress S, Reynolds DM, Chen L, Nazor KL, Baur J, Singh AM, Loring JF, Metzger M et al (2019)
Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair.
Cell Reports, 26(10):2566-+.

De Mattos IB, Nischwitz SP, Tuca AC, Groeber-Becker F, Funk M, Birngruber T, Mautner S, Kamolz LP, Holzer JC (2019)
Delivery of antiseptic solutions by a bacterial cellulose wound dressing: Uptake, release and antibacterial efficacy of octenidine and povidone-iodine.
Burns, 45(3):746-748.

De Mattos IB, Holzer JC, Tuca AC, Groeber-Becker F, Funk M, Popp D, Mautner S, Birngruber T, Kamolz LP (2019)
Uptake of PHMB in a bacterial nanocellulose-based wound dressing: A feasible clinical procedure.
Burns, 45(4), 898-904.

Fahmy-Garcia S, Farrell E, Witte-Bouma J, Robbesom-van den Berge I, Suarez M, Mumcuoglu D, Wailes H, Kluijtmans SGJM, van der Eerden BCJ, van Osch GJVM et al (2019)
Follistatin Effects in Migration, Vascularization, and Osteogenesis in vitro and Bone Repair in vivo.
Frontiers in Bioengineering and Biotechnology, 7.

Gangloff N, Hoeferth M, Stepanenko V, Sochor B, Schummer B, Nickel J, Walles H, Hanke R, Wuerthner F, Zuckermann RN et al (2019)
Linking two worlds in polymer chemistry: The influence of block uniformity and dispersity in amphiphilic block copolypeptoids on their self-assembly.
Biopolymers, 110(4).

Gomes SFM, Westermann AJ, Sauerwein T, Hertlein T, Forstner KU, Ohlsen K, Metzger M, Shusta EV, Kim BJ, Appelt-Menzel A et al (2019)
Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection.
Frontiers in Microbiology, 10.

Heydarian M, Yang T, Schweinlin M, Steinke M, Walles H, Rudel T, Kozjak-Paylovic V (2019)
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
Frontiers in Microbiology, 10.

Ingendoh-Tsakmakidis A, Mikolai C, Winkel A, Szafranski SP, Flak CS, Rossi A, Walles H, Stiesch M (2019)
Commensal and pathogenic biofilms differently modulate peri-implant oral mucosa in an organotypic model.
Cellular Microbiology, 21(10).

Jannasch M, Gaetzner S, Groeber F, Weigel T, Walles H, Schmitz T, Hansmann J (2019) An in vitro model mimics the contact of biomaterials to blood components and the reaction of surrounding soft tissue.
Acta Biomater 2019, 89:227-241.

Kailayangiri S, Altvater B, Lesch S, Balbach S, Goettlich C, Kuehnemundt J, Mikesch J-H, Schelhaas S, Jamitzky S, Meltzer J et al (2019)
EZH2 Inhibition in Ewing Sarcoma Upregulates G(D2) Expression for Targeting with Gene-Modified T- Cells.
Molecular Therapy, 27(5):933-946.

Kampik D, Tarau I-S, Han H, Walles H, Groeber-Becker FK, Hillenkamp J, Lotz C (2019) A 3D-hemi-cornea wound healing model for pre-clinical testing.
Investigative Ophthalmology and Visual Science, 60(9).

Karl F, Wußmann M, Kreß L, Malzacher T, Fey P, Groeber‐Becker F, & Üçeyler N (2019) Patient‐derived in vitro skin models for investigation of small fiber pathology.
Annals of clinical and translational neurology, 6(9): 1797-1806.

Kiesewetter L, Littau L, Walles H, Boccaccini AR, Groeber-Becker F (2019) Reepithelialization in focus: Non-invasive monitoring of epidermal wound healing in vitro.
Biosensors and Bioelectronics, 142, 111555.

Kim M, Rosenbaum C, Schlegel N, Grumaz C, Sohn K, Isbert C, Walles H, Metzger M (2019)
Obstructed defecationan enteric neuropathy? An exploratory study of patient samples. International Journal of Colorectal Disease, 34(1):193-196.

Kremer A, Wussmann M, Herrmann M, Raghunath M, Walles H (2019)
Ciclopirox olamine promotes the angiogenic response of endothelial cells and mesenchymal stem cells.
Clin Hemorheol Microcirc.

Kunz M, Jeromin J, Fuchs M, Christoph J, Veronesi G, Flentje M, Nietzer S, Dandekar G, Dandekar T (2019)
In silico signaling modeling to understand cancer pathways and treatment responses. Briefings in bioinformatics.

Lodes NT, Seidensticker K, Perniss A, Nietzer SL, Oberwinkler H, May T, Walles T, Hebestreit H, Hackenberg S, Steinke M (2019)
Investigation on ciliary functionality of different airway epithelial cell lines in 3D cell culture.
Tissue engineering Part A.

Lohr D, Terekhov M, Weng AM, Schroeder A, Walles H, Schreiber LM (2019)
Spin echo based cardiac diffusion imaging at 7T: An ex vivo study of the porcine heart at 7T and 3T.
Plos One, 14(3).

Lohr D, Terekhov M, Weng AM, Schroeder A, Walles H, Schreiber LM (2019)
Spin echo based cardiac diffusion imaging at 7T: An ex vivo study of the porcine heart at 7T and 3T.
Plos One, 14(3):e0213994.

Lotz C, Kieswetter L, Hansmann J, Walles H, Groeber-Becker F (2019)
Impedance spectroscopy as a method to discriminate between all GHS categories for eye irritation in vitro.
Toxicology Letters, 314:S304-S305.

Luebtow MM, Nelke LC, Seifert J, Kuehnemundt J, Sahay G, Dandekar G, Nietzer SL, Luxenhofer R (2019)
Drug induced micellization into ultra-high capacity and stable curcumin nanoformulations: Physico-chemical characterization and evaluation in 2D and 3D in vitro models.
Journal of Controlled Release, 303:162-180.

Matei A-E, Chen C-W, Kiesewetter L, Gyorfi A-H, Li Y-N, Trinh-Minh T, Xu X, Tran Manh C, van Kuppevelt T, Hansmann J et al (2019)
Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs.
Annals of the rheumatic diseases, 78(12):1686-1692.

Meir M, Burkard N, Ungewiss H, Diefenbacher M, Flemming S, Kannapin F, Germer C-T, Schweinlin M, Metzger M, Waschke J et al (2019)
Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease.
Journal of Clinical Investigation, 129(7):2824-2840.

Mikolai C, Ingendoh-Tsakmakidis A, Winkel A, Kommerein N, Falk CS, Rossi A, Walles H, Stiesch M (2019)
Session 10: Biofilms Implant related infections.
Biomedizinische Technik Biomedical engineering, 64(s1):63-65.

Nischwitz SP, de Mattos IB, Hofmann E, Groeber-Becker F, Funk M, Mohr GJ, Branski LK, Mautner S I, Kamolz LP (2019)
Continuous pH monitoring in wounds using a composite indicator dressing—A feasibility study.
Burns, 45(6), 1336-1341.

Schellenberger MT, Bock U, Hennen J, Groeber-Becker F, Walles H, Bloemeke B (2019)
A coculture system composed of THP-1 cells and 3D reconstructed human epidermis to assess activation of dendritic cells by sensitizing chemicals after topical exposure.
Toxicol in Vitro, 57:62-66.

Schmitteckert S, Mederer T, Roeth R, Guenther P, Holland-Cunz S, Metzger M, Samstag Y, Schroeder-Braunstein J, Wabnitz G, Kurzhals S et al (2019)
Postnatal human enteric neurospheres show a remarkable molecular complexity. Neurogastroenterology and Motility, 31(10).

Schwedhelm I, Zdzieblo D, Appelt-Menzel A, Berger C, Schmitz T, Schuldt B, Franke A, Muller FJ, Pless O, Schwarz T et al (2019)
Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors.
Sci Rep, 9(1):12297.

Stuckensen K, Lamo-Espinosa JM, Muinos-Lopez E, Ripalda-Cemborain P, Lopez-Martinez T, Iglesias E, Abizanda G, Andreu I, Flandes-Iparraguirre M, Pons-Villanueva J et al (2019)
Anisotropic Cryostructured Collagen Scaffolds for Efficient Delivery of RhBMP-2 and Enhanced Bone Regeneration.
Materials (Basel), 12(19).

Wallstabe L, Goettlich C, Nelke LC, Kuehnemundt J, Schwarz T, Nerreter T, Einsele H, Walles H, Dandekar G, Nietzer SL et al (2019)
ROR1-CAR T cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models.
Jci Insight, 4(18).

Weigel T, Schmitz T, Jannasch M, Schurlein S, Al Hijailan R, Suliman S, Walles H, Hansmann J (2019)
Session 9: Biomaterials-Elektrospinning.
Biomed Tech (Berl), 64(s1):59-62.


Appelt-Menzel A, Cubukova A, Metzger M (2018)
Establishment of a Human Blood-Brain Barrier Co-Culture Model Mimicking the Neurovascular Unit Using Induced Pluripotent Stem Cells.
Current protocols in stem cell biology, 47(1):e62-e62.

Berger C, Bjorlykke Y, Muehlemann M, Raeder H, Walles H, Metzger M, Zdzieblo D (2018)
A pancreas-specific ECM scaffold - uman iPS cell culture and pancreatic differentiation goes 3D.
Diabetologia, 61:S192-S192.

Boepple K, Dong M, Davis E, Schueler J, Walles H, Hickman J, Aulitzky WE, van der Kuip H (2018)
Perfusion air culture of tissue slices: A new method to cultivate tumor tissue with minimal culture-dependent tissue stress.
Cancer Res, 78(13).

Burghartz M, Lennartz S, Schweinlin M, Hagen R, Kleinsasser N, Hackenberg S, Steussloff G, Scherzad A, Radeloff K, Ginzkey C et al (2018)
Development of Human Salivary Gland-Like Tissue In Vitro.
Tissue Eng Pt A, 24(3-4):301-309.

Confalonieri D, Schwab A, Walles H, Ehlicke F (2018)
Advanced Therapy Medicinal Products: A Guide for Bone Marrow-derived MSC Application in Bone and Cartilage Tissue Engineering.
Tissue Eng Part B-Re, 24(2):155-169.

Ditgen D, Anandarajah EM, Reinhardt A, Younis AE, Witt S, Hansmann J, Lorenz E, Garcia-Hernandez M, Paclik D, Soblik H et al (2018)
Comparative characterization of two galectins excreted-secreted from intestine-dwelling parasitic versus free-living females of the soil-transmitted nematode Strongyloides. Molecular and Biochemical Parasitology, 225:73-83.

Fahmy-Garcia S, van Driel M, Witte-Buoma J, Walles H, van Leeuwen JPTM, van Osch GJVM, Farrell E (2018)
NELL-1, HMGB1, and CCN2 Enhance Migration and Vasculogenesis, But Not Osteogenic Differentiation Compared to BMP2.
Tissue Eng Pt A, 24(3-4):207-218.

Gottlich C, Kunz M, Zapp C, Nietzer SL, Walles H, Dandekar T, Dandekar G (2018)
A combined tissue-engineered/insilico signature tool patient stratification in lung cancer. Mol Oncol, 12(8):1264-1285.

Hafen B, Wiesner S, Schlegelmilch K, Keller A, Seefried L, Ebert R, Walles H, Jakob F, Schuetze N (2018)
Physical contact between mesenchymal stem cells and endothelial precursors induces distinct signatures with relevance to the very early phase of regeneration.
Journal of Cellular Biochemistry, 119(11):9122-9140.

Hansmann J, Egger D, Kasper C (2018)
Advanced Dynamic Cell and Tissue Culture.
Bioengineering-Basel, 5(3):65-Article No.: 65.

Kress S, Baur J, Otto C, Burkard N, Braspenning J, Walles H, Nickel J, Metzger M, (2018) Evaluation of a Miniaturized Biologically Vascularized Scaffold in vitro and in vivo.
Sci Rep, 8(1):4719.

Lohr D, Terekhov M, Weng AM, Schroeder A, Walles H, Schreiber LM, (2018)
Possible benefits of ultra high field MRI in cardiac diffusion tensor imaging. European Journal of Heart Failure, 20:149-150.

Lotz C, Kiesewetter L, Schmid FF, Hansmann J, Walles H, Groeber-Becker F (2018) Replacing the Draize eye test: Impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation.
Sci Rep-Uk, 8.

Massie I, Spaniol K, Barbian A, Geerling G, Metzger M, Schrader S (2018)
Development of lacrimal gland spheroids for lacrimal gland tissue regeneration.
Journal of Tissue Engineering and Regenerative Medicine, 12(4):E2001-E2009.

Muehlemann M, Zdzieblo D, Friedrich A, Berger C, Otto C, Walles H, Koepsell H, Metzger M (2018)
Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet.
Molecular Metabolism, 13:67-76.

Mumcuoglu D, de Miguel L, Jekhmane S, Siverino C, Nickel J, Mueller TD, van Leeuwen JP, van Osch GJ, Kluijtmans SG (2018)
Collagen I derived recombinant protein microspheres as novel delivery vehicles for bone morphogenetic protein-2.
Mater Sci Eng C Mater Biol Appl, 84:271-280.

Mumcuoglu D, Fahmy-Garcia S, Ridwan Y, Nickel J, Farrell E, Kluijtmans SGJM, van Osch GJVM (2018)
Injectable BMP-2 delivery system based on collagen-derived microspheres and alginate induced bone formation in a time- and dose-dependent manner.
European Cells & Materials, 35:242-254.

Munoz MS, Confalonieri D, Walles H, van Dongen EMWM, Dandekar G (2018) Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model.
Jove-J Vis Exp (132).

Nickel J, ten Dijke P, Mueller TD (2018)
TGF-beta family co-receptor function and signaling.
Acta Biochimica Et Biophysica Sinica, 50(1):12-36.

Pali M, Terekhov M, Wittke C, Wagner N, Schroeder A, Walles H, Erguen S, Zernecke-Madsen A, Schreiber LM (2018)
High-Resolution and Semidynamic Vessel Wall Imaging Kinetics obtained from Stable Radical MRI in ex-vivo Porcine Aorta.
European Journal of Heart Failure, 20:522-523.

Ramani-Mohan R-K, Schwedhelm I, Finne-Wistrand A, Krug M, Schwarz T, Jakob F, Walles H, Hansmann J (2018)
Deformation strain is the main physical driver for skeletal precursors to undergo osteogenesis in earlier stages of osteogenic cell maturation.
Journal of Tissue Engineering and Regenerative Medicine, 12(3):E1474-E1479.

Reuter C, Alzheimer M, Walles H, Oelschlaeger TA (2018)
An adherent mucus layer attenuates the genotoxic effect of colibactin.
Cellular Microbiology, 20(2).

Ribitsch I, Peham C, Ade N, Durr J, Handschuh S, Schramel JP, Vogl C, Walles H, Egerbacher M, Jenner F (2018)
Structure-Function relationships of equine menisci.
Plos One, 13(3).

Rosenbaum C, Boettner M, Wedel T, Metzger M (2018)
Laser-Capture Microdissection for Layer-Specific Analysis of Enteric Ganglia. In: Laser Capture Microdissection: Methods and Protocols, 3rd Edition.
Edited by Murray GI, vol. 1723; 361-369.

Schellenberger MT, Bock U, Hennen J, Groeber-Becker F, Walles H, Bloemeke B (2018) An in vitro coculture system composed of THP-1 cells and 3D reconstructed human epidermis to assess activation of dendritic cells by sensitizing chemicals.
N-S Arch Pharmacol, 391:S49-S49.

Schliermann A, Nickel J (2018)
Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling.
Int J Mol Sci, 19(10).

Schmid R, Tarau I-S, Rossi A, Leonhardt S, Schwarz T, Schuerlein S, Lotz C, Hansmann J (2018) 
In Vivo-Like Culture Conditions in a Bioreactor Facilitate Improved Tissue Quality in Corneal Storage.
Biotechnol J, 13(1).

Schmid FF, Groeber-Becker F, Schwab S, Thude S, Goebeler M, Walles H, Hansmann J (2018)
A Standardized Method Based on Pigmented Epidermal Models Evaluates Sensitivity Against UV-Irradiation.
Altex-Altern Anim Ex, 35(3):390-396.

Siverino C, Tabisz B, Luhmann T, Meinel L, Muller T, Walles H, Nickel J (2018)
Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry. J Vis Exp (133).

Steinke M, Zunhammer F, Chatzopoulou EI, Teller H, Schuetze K, Walles H, Raedler JO, Gruettner C (2018)
Rapid Analysis of Cell-Nanoparticle Interactions using Single-Cell Raman Trapping Microscopy.
Angewandte Chemie-International Edition 2018, 57(18):4946-4950.

Stuckensen K, Schwab A, Knauer M, Muinos-Lopez E, Ehlicke F, Reboredo J, Granero-Molto F, Gbureck U, Prosper F, Walles H et al (2018)
Tissue Mimicry in Morphology and Composition Promotes Hierarchical Matrix Remodeling of Invading Stem Cells in Osteochondral and Meniscus Scaffolds.
Advanced Materials, 30(28).

Suarez Munoz M, Confalonieri D, Walles H, van Dongen E, Dandekar G (2018) Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model. J Vis Exp (132).

Weigel T, Schmitz T, Pfister T, Gaetzner S, Jannasch M, Al-Hijailan R, Schuerlein S, Suliman S, Mustafa K, Hansmann J (2018)
A three-dimensional hybrid pacemaker electrode seamlessly integrates into engineered, functional human cardiac tissue in vitro.
Sci Rep-Uk, 8.


Portraitfoto von Dr. Antje Appelt-Menzel

Antje Appelt-Menzel

Stellvertretende kommissarische Lehrstuhlleitung

+49 931 31-80771

Portraitfoto von Dr. Joachim Nickel

Joachim Nickel

Stellvertretende Kommissarische Lehrstuhlleitung

+49 931 31-84122



Anna Stefl
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