Die Publikationen des Lehrstuhls TERM

Der Lehrstuhl TERM veröffentlicht regelmäßig Forschungsergebnisse in nationalen und internationalen Veröffentlichungsforen. Im Folgenden ist eine Auswahl der Publikationen der vergangenen Jahre aufgelistet.


Heydarian M, Schweinlin M, Schwarz T, Rawal R, Walles H, Metzger M, Rudel T, Kozjak-Pavlovic V (2021) 
Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity. 
J Tissue Eng. 2021 Jan 28;12:2041731420988802. (IF 7.8)

Trujillo-Viera J, El-Merahbi R, Schmidt V, Karwen T, Loza-Valdes A, Strohmeyer A, Reuter S, Noh M, Wit M, Hawro I, Mocek S, Fey C, Mayer AE, Löffler MC, Wilhelmi I, Metzger M, Ishikawa E, Yamasaki S, Rau M, Geier A, Hankir M, Seyfried F, Klingenspor M, Sumara G (2021)
Protein Kinase D2 drives chylomicron-mediated lipid transport in the intestine and promotes obesity. 
EMBO Mol Med. 2021 May 7;13(5):e13548. (IF 10.3)


Alzheimer M, Sarah L, Svensson SL, König F, Schweinlin M, Metzger M, Walles H, Sharma CM (2020)
A Three-Dimensional Intestinal Tissue Model Reveals Factors and Small Regulatory RNAs Important for Colonization With Campylobacter Jejuni.
PLoS Pathog 2020 Feb 18;16(2):e1008304. doi: 10.1371/journal.ppat.1008304.

Berger C, Bjørlykke Y, Hahn L, Mühlemann M, Kress S, Walles H, Luxenhofer R, Ræder H, Metzger M, Zdzieblo D (2020)
Matrix decoded - A pancreatic extracellular matrix with organ specific cues guiding human iPSC differentiation.
Biomaterials 244:119766. 2020. doi: 10.1016/j.biomaterials.2020.119766.

Burghartz M, Taeger J, Metzger M, Scherzad M, Gehrke T, Ickrath P, Kolb E, Kleinsasser N, Hagen R, Hackenberg S (2020)
Investigation of Cellular Function and DNA Integrity during 2D in vitro Culture of Human Salivary Gland Epithelial Cells. 
Cells Tissues Organs 2020, 208, 66-75. (IF 2.0)

Berger C, Zdzieblo D (2020)
Glucose Transporters in Pancreatic Islets.
Pflügers Archiv - European Journal of Physiology. 2020. doi: 10.1007/s00424-020-02383-4.

Däullary T, Fey C, Berger C, Metzger M, Zdzieblo D (2020)
Bioartificial gut – current state of small intestinal tissue engineering.
Biomaterials for Organ and Tissue Regeneration, New Technologies and Future Prospects. 2020. ISBN: 978-0-08-102906-0. doi: 10.1016/C2018-0-02069-1.

Fey C, Betz J, Rosenbaum C, Kralisch D, Vielreicher M, Friedrich O, Metzger M, Zdzieblo D (2020)
Bacterial nanocellulose as novel carrier for intestinal epithelial cells in drug delivery studies.
Mater Sci Eng C Mater Biol Appl. 109:110613. 2020. doi: 10.1016/j.msec.2019.110613.

Hoffmann J, Fayez S, Hofmann M, Scheiner M, Maher P, Maurice T, . . . Appelt-Menzel A. (2020)
Sterubin: enantioresolution and configurational stability, enantiomeric purity in nature, and neuroprotective activity in vitro and in vivo.
Chemistry. doi:10.1002/chem.202001264.

Li P, Lee HR, Chandel S, Lotz C, Groeber-Becker FK, Dembski S, Ossikovski R, Ma H, Novikova T (2020). Analysis of tissue microstructure with Mueller microscopy: logarithmic decomposition and Monte Carlo modeling. J Biomed Opt. 2020 Jan;25(1):1-11. doi: 10.1117/1.JBO.25.1.015002.

Lodes N, Seidensticker K, Perniss A, Nietzer S, Oberwinkler H, May T, Walles T, Hebestreit H, Hackenberg S, Steinke M (2020)
Investigation on Ciliary Functionality of Different Airway Epithelial Cell Lines in Three-Dimensional Cell Culture.
Tissue Eng Part A. 2020 Apr;26(7-8):432-440. doi: 10.1089/ten.TEA.2019.0188.

Lubtow MM, Oerter S, Quader S, Jeanclos E, Cubukova A, Krafft M, . . . Luxenhofer R (2020)
In vitro blood-brain-barrier permeability and cytotoxicity of atorvastatin-loaded nanoformulation against glioblastoma in 2D and 3D models.
Mol Pharm. doi:10.1021/acs.molpharmaceut.9b01117.

Meir M, Burkard N, Ungewiß H, Diefenbacher M, Flemming S, Kannapin F, Germer CT, Schweinlin M, Metzger M, Waschke J, Schlegel N (2020)
Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease.
J Clin Invest. 2019 Jun 17;129(7):2824-2840. doi: 10.1172/JCI120261.

Meir M, Salm J, Fey C, Schweinlin M, Kollmann C, Kannapin F, Germer CT, Waschke J, Beck C, Burkard N, Metzger M, Schlegel N (2020)
Enteroids generated from patients with severe inflammation in Crohn's disease maintain alterations of junctional proteins.
J Crohns Colitis. 2020 Apr 28:jjaa085. doi: 10.1093/ecco-jcc/jjaa085.

Rackwitz L, Pullig O, Nöth U (2020). Prevention of Osteoarthritis and Future Strategies for Osteoarthritis Therapy – an Orthopaedic and Trauma-Surgical Perspective. Akt Rheumatol 2020; 45(01): 96-105, doi: 10.1055/a-1036-4100.

Schulte LN, Schweinlin M, Westermann AJ, Janga H, Santos SC, Appenzeller S, Walles H, Vogel J, Metzger M (2020)
An Advanced Human Intestinal Coculture Model Reveals Compartmentalized Host and Pathogen Strategies During Salmonella Infection.
mBio 2020 Feb 18;11(1):e03348-19. doi: 10.1128/mBio.03348-19.

Schwedhelm I, Zdzieblo D, Appelt-Menzel A, Berger C, Schmitz T, Schuldt B, Franke A, Müller FJ, Pless O, Schwarz T, Wiedemann P, Walles H, Hansmann J (2020)
Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors.
Sci Rep 23;9(1):12297. 2019. doi: 10.1038/s41598-019-48814-w.

Stüber T, Monjezi R, Wallstabe L, Kühnemundt J, Nietzer SL, Dandekar G, Wöckel A, Einsele H, Wischhusen J, Hudecek M (2020)
Inhibition of TGF-β-receptor signaling augments the antitumor function of ROR1-specific CAR T-cells against triple-negative breast cancer.
J Immunother Cancer. 2020 Apr;8(1):e000676. doi: 10.1136/jitc-2020-000676.

Wallstabe J, Bussemer L, Groeber-Becker F, Freund L, Alb M, Dragan M, Waaga-Gasser AM, Jakubietz R, Kneitz H, Rosenwald A, Rebhan S, Walles H, Mielke S (2020)
Inflammation-induced tissue damage mimicking GvHD in human skin models as test-platform for immunotherapeutics.
ALTEX. 2020 Apr 14. doi: 10.14573/altex.1907181.


Belka J, Nickel J, Kurth DG (2019)
Growth on Metallo-Supramolecular Coordination Polyelectrolyte (MEPE) Stimulates Osteogenic Differentiation of Human Osteosarcoma Cells (MG63) and Human Bone Marrow Derived Mesenchymal Stem Cells.
Polymers (Basel), 11(7).

Boepple K, Dong M, Winkler B, Janssen N, Kleih M, Essmann F, Walles H, Ott G, Schwab M, Aulitzky WE (2019)
An advanced non-animal model for cultivation and pharmacological perturbation of human tumor tissue.
N-S Arch Pharmacol, 392:S79-S79.

Bode KJ, Mueller S, Schweinlin M, Metzger M, Brunner T (2019)
A fast and simple fluorometric method to detect cell death in 3D intestinal organoids. Biotechniques, 67(1):23-28.

Colunga T, Hayworth M, Kress S, Reynolds DM, Chen L, Nazor KL, Baur J, Singh AM, Loring JF, Metzger M et al (2019)
Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair.
Cell Reports, 26(10):2566-+.

De Mattos IB, Nischwitz SP, Tuca AC, Groeber-Becker F, Funk M, Birngruber T, Mautner S, Kamolz LP, Holzer JC (2019)
Delivery of antiseptic solutions by a bacterial cellulose wound dressing: Uptake, release and antibacterial efficacy of octenidine and povidone-iodine.
Burns, 45(3):746-748.

De Mattos IB, Holzer JC, Tuca AC, Groeber-Becker F, Funk M, Popp D, Mautner S, Birngruber T, Kamolz LP (2019)
Uptake of PHMB in a bacterial nanocellulose-based wound dressing: A feasible clinical procedure.
Burns, 45(4), 898-904.

Fahmy-Garcia S, Farrell E, Witte-Bouma J, Robbesom-van den Berge I, Suarez M, Mumcuoglu D, Wailes H, Kluijtmans SGJM, van der Eerden BCJ, van Osch GJVM et al (2019)
Follistatin Effects in Migration, Vascularization, and Osteogenesis in vitro and Bone Repair in vivo.
Frontiers in Bioengineering and Biotechnology, 7.

Gangloff N, Hoeferth M, Stepanenko V, Sochor B, Schummer B, Nickel J, Walles H, Hanke R, Wuerthner F, Zuckermann RN et al (2019)
Linking two worlds in polymer chemistry: The influence of block uniformity and dispersity in amphiphilic block copolypeptoids on their self-assembly.
Biopolymers, 110(4).

Gomes SFM, Westermann AJ, Sauerwein T, Hertlein T, Forstner KU, Ohlsen K, Metzger M, Shusta EV, Kim BJ, Appelt-Menzel A et al (2019)
Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection.
Frontiers in Microbiology, 10.

Heydarian M, Yang T, Schweinlin M, Steinke M, Walles H, Rudel T, Kozjak-Paylovic V (2019)
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
Frontiers in Microbiology, 10.

Ingendoh-Tsakmakidis A, Mikolai C, Winkel A, Szafranski SP, Flak CS, Rossi A, Walles H, Stiesch M (2019)
Commensal and pathogenic biofilms differently modulate peri-implant oral mucosa in an organotypic model.
Cellular Microbiology, 21(10).

Jannasch M, Gaetzner S, Groeber F, Weigel T, Walles H, Schmitz T, Hansmann J (2019) An in vitro model mimics the contact of biomaterials to blood components and the reaction of surrounding soft tissue.
Acta Biomater 2019, 89:227-241.

Kailayangiri S, Altvater B, Lesch S, Balbach S, Goettlich C, Kuehnemundt J, Mikesch J-H, Schelhaas S, Jamitzky S, Meltzer J et al (2019)
EZH2 Inhibition in Ewing Sarcoma Upregulates G(D2) Expression for Targeting with Gene-Modified T- Cells.
Molecular Therapy, 27(5):933-946.

Kampik D, Tarau I-S, Han H, Walles H, Groeber-Becker FK, Hillenkamp J, Lotz C (2019) A 3D-hemi-cornea wound healing model for pre-clinical testing.
Investigative Ophthalmology and Visual Science, 60(9).

Karl F, Wußmann M, Kreß L, Malzacher T, Fey P, Groeber‐Becker F, & Üçeyler N (2019) Patient‐derived in vitro skin models for investigation of small fiber pathology.
Annals of clinical and translational neurology, 6(9): 1797-1806.

Kiesewetter L, Littau L, Walles H, Boccaccini AR, Groeber-Becker F (2019) Reepithelialization in focus: Non-invasive monitoring of epidermal wound healing in vitro.
Biosensors and Bioelectronics, 142, 111555.

Kim M, Rosenbaum C, Schlegel N, Grumaz C, Sohn K, Isbert C, Walles H, Metzger M (2019)
Obstructed defecationan enteric neuropathy? An exploratory study of patient samples. International Journal of Colorectal Disease, 34(1):193-196.

Kremer A, Wussmann M, Herrmann M, Raghunath M, Walles H (2019)
Ciclopirox olamine promotes the angiogenic response of endothelial cells and mesenchymal stem cells.
Clin Hemorheol Microcirc.

Kunz M, Jeromin J, Fuchs M, Christoph J, Veronesi G, Flentje M, Nietzer S, Dandekar G, Dandekar T (2019)
In silico signaling modeling to understand cancer pathways and treatment responses. Briefings in bioinformatics.

Lodes NT, Seidensticker K, Perniss A, Nietzer SL, Oberwinkler H, May T, Walles T, Hebestreit H, Hackenberg S, Steinke M (2019)
Investigation on ciliary functionality of different airway epithelial cell lines in 3D cell culture.
Tissue engineering Part A.

Lohr D, Terekhov M, Weng AM, Schroeder A, Walles H, Schreiber LM (2019)
Spin echo based cardiac diffusion imaging at 7T: An ex vivo study of the porcine heart at 7T and 3T.
Plos One, 14(3).

Lohr D, Terekhov M, Weng AM, Schroeder A, Walles H, Schreiber LM (2019)
Spin echo based cardiac diffusion imaging at 7T: An ex vivo study of the porcine heart at 7T and 3T.
Plos One, 14(3):e0213994.

Lotz C, Kieswetter L, Hansmann J, Walles H, Groeber-Becker F (2019)
Impedance spectroscopy as a method to discriminate between all GHS categories for eye irritation in vitro.
Toxicology Letters, 314:S304-S305.

Luebtow MM, Nelke LC, Seifert J, Kuehnemundt J, Sahay G, Dandekar G, Nietzer SL, Luxenhofer R (2019)
Drug induced micellization into ultra-high capacity and stable curcumin nanoformulations: Physico-chemical characterization and evaluation in 2D and 3D in vitro models.
Journal of Controlled Release, 303:162-180.

Matei A-E, Chen C-W, Kiesewetter L, Gyorfi A-H, Li Y-N, Trinh-Minh T, Xu X, Tran Manh C, van Kuppevelt T, Hansmann J et al (2019)
Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs.
Annals of the rheumatic diseases, 78(12):1686-1692.

Meir M, Burkard N, Ungewiss H, Diefenbacher M, Flemming S, Kannapin F, Germer C-T, Schweinlin M, Metzger M, Waschke J et al (2019)
Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease.
Journal of Clinical Investigation, 129(7):2824-2840.

Mikolai C, Ingendoh-Tsakmakidis A, Winkel A, Kommerein N, Falk CS, Rossi A, Walles H, Stiesch M (2019)
Session 10: Biofilms Implant related infections.
Biomedizinische Technik Biomedical engineering, 64(s1):63-65.

Nischwitz SP, de Mattos IB, Hofmann E, Groeber-Becker F, Funk M, Mohr GJ, Branski LK, Mautner S I, Kamolz LP (2019)
Continuous pH monitoring in wounds using a composite indicator dressing—A feasibility study.
Burns, 45(6), 1336-1341.

Schellenberger MT, Bock U, Hennen J, Groeber-Becker F, Walles H, Bloemeke B (2019)
A coculture system composed of THP-1 cells and 3D reconstructed human epidermis to assess activation of dendritic cells by sensitizing chemicals after topical exposure.
Toxicol in Vitro, 57:62-66.

Schmitteckert S, Mederer T, Roeth R, Guenther P, Holland-Cunz S, Metzger M, Samstag Y, Schroeder-Braunstein J, Wabnitz G, Kurzhals S et al (2019)
Postnatal human enteric neurospheres show a remarkable molecular complexity. Neurogastroenterology and Motility, 31(10).

Schwedhelm I, Zdzieblo D, Appelt-Menzel A, Berger C, Schmitz T, Schuldt B, Franke A, Muller FJ, Pless O, Schwarz T et al (2019)
Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors.
Sci Rep, 9(1):12297.

Stuckensen K, Lamo-Espinosa JM, Muinos-Lopez E, Ripalda-Cemborain P, Lopez-Martinez T, Iglesias E, Abizanda G, Andreu I, Flandes-Iparraguirre M, Pons-Villanueva J et al (2019)
Anisotropic Cryostructured Collagen Scaffolds for Efficient Delivery of RhBMP-2 and Enhanced Bone Regeneration.
Materials (Basel), 12(19).

Wallstabe L, Goettlich C, Nelke LC, Kuehnemundt J, Schwarz T, Nerreter T, Einsele H, Walles H, Dandekar G, Nietzer SL et al (2019)
ROR1-CAR T cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models.
Jci Insight, 4(18).

Weigel T, Schmitz T, Jannasch M, Schurlein S, Al Hijailan R, Suliman S, Walles H, Hansmann J (2019)
Session 9: Biomaterials-Elektrospinning.
Biomed Tech (Berl), 64(s1):59-62.


Appelt-Menzel A, Cubukova A, Metzger M (2018)
Establishment of a Human Blood-Brain Barrier Co-Culture Model Mimicking the Neurovascular Unit Using Induced Pluripotent Stem Cells.
Current protocols in stem cell biology, 47(1):e62-e62.

Berger C, Bjorlykke Y, Muehlemann M, Raeder H, Walles H, Metzger M, Zdzieblo D (2018)
A pancreas-specific ECM scaffold - uman iPS cell culture and pancreatic differentiation goes 3D.
Diabetologia, 61:S192-S192.

Boepple K, Dong M, Davis E, Schueler J, Walles H, Hickman J, Aulitzky WE, van der Kuip H (2018)
Perfusion air culture of tissue slices: A new method to cultivate tumor tissue with minimal culture-dependent tissue stress.
Cancer Res, 78(13).

Burghartz M, Lennartz S, Schweinlin M, Hagen R, Kleinsasser N, Hackenberg S, Steussloff G, Scherzad A, Radeloff K, Ginzkey C et al (2018)
Development of Human Salivary Gland-Like Tissue In Vitro.
Tissue Eng Pt A, 24(3-4):301-309.

Confalonieri D, Schwab A, Walles H, Ehlicke F (2018)
Advanced Therapy Medicinal Products: A Guide for Bone Marrow-derived MSC Application in Bone and Cartilage Tissue Engineering.
Tissue Eng Part B-Re, 24(2):155-169.

Ditgen D, Anandarajah EM, Reinhardt A, Younis AE, Witt S, Hansmann J, Lorenz E, Garcia-Hernandez M, Paclik D, Soblik H et al (2018)
Comparative characterization of two galectins excreted-secreted from intestine-dwelling parasitic versus free-living females of the soil-transmitted nematode Strongyloides. Molecular and Biochemical Parasitology, 225:73-83.

Fahmy-Garcia S, van Driel M, Witte-Buoma J, Walles H, van Leeuwen JPTM, van Osch GJVM, Farrell E (2018)
NELL-1, HMGB1, and CCN2 Enhance Migration and Vasculogenesis, But Not Osteogenic Differentiation Compared to BMP2.
Tissue Eng Pt A, 24(3-4):207-218.

Gottlich C, Kunz M, Zapp C, Nietzer SL, Walles H, Dandekar T, Dandekar G (2018)
A combined tissue-engineered/insilico signature tool patient stratification in lung cancer. Mol Oncol, 12(8):1264-1285.

Hafen B, Wiesner S, Schlegelmilch K, Keller A, Seefried L, Ebert R, Walles H, Jakob F, Schuetze N (2018)
Physical contact between mesenchymal stem cells and endothelial precursors induces distinct signatures with relevance to the very early phase of regeneration.
Journal of Cellular Biochemistry, 119(11):9122-9140.

Hansmann J, Egger D, Kasper C (2018)
Advanced Dynamic Cell and Tissue Culture.
Bioengineering-Basel, 5(3):65-Article No.: 65.

Kress S, Baur J, Otto C, Burkard N, Braspenning J, Walles H, Nickel J, Metzger M, (2018) Evaluation of a Miniaturized Biologically Vascularized Scaffold in vitro and in vivo.
Sci Rep, 8(1):4719.

Lohr D, Terekhov M, Weng AM, Schroeder A, Walles H, Schreiber LM, (2018)
Possible benefits of ultra high field MRI in cardiac diffusion tensor imaging. European Journal of Heart Failure, 20:149-150.

Lotz C, Kiesewetter L, Schmid FF, Hansmann J, Walles H, Groeber-Becker F (2018) Replacing the Draize eye test: Impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation.
Sci Rep-Uk, 8.

Massie I, Spaniol K, Barbian A, Geerling G, Metzger M, Schrader S (2018)
Development of lacrimal gland spheroids for lacrimal gland tissue regeneration.
Journal of Tissue Engineering and Regenerative Medicine, 12(4):E2001-E2009.

Muehlemann M, Zdzieblo D, Friedrich A, Berger C, Otto C, Walles H, Koepsell H, Metzger M (2018)
Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet.
Molecular Metabolism, 13:67-76.

Mumcuoglu D, de Miguel L, Jekhmane S, Siverino C, Nickel J, Mueller TD, van Leeuwen JP, van Osch GJ, Kluijtmans SG (2018)
Collagen I derived recombinant protein microspheres as novel delivery vehicles for bone morphogenetic protein-2.
Mater Sci Eng C Mater Biol Appl, 84:271-280.

Mumcuoglu D, Fahmy-Garcia S, Ridwan Y, Nickel J, Farrell E, Kluijtmans SGJM, van Osch GJVM (2018)
Injectable BMP-2 delivery system based on collagen-derived microspheres and alginate induced bone formation in a time- and dose-dependent manner.
European Cells & Materials, 35:242-254.

Munoz MS, Confalonieri D, Walles H, van Dongen EMWM, Dandekar G (2018) Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model.
Jove-J Vis Exp (132).

Nickel J, ten Dijke P, Mueller TD (2018)
TGF-beta family co-receptor function and signaling.
Acta Biochimica Et Biophysica Sinica, 50(1):12-36.

Pali M, Terekhov M, Wittke C, Wagner N, Schroeder A, Walles H, Erguen S, Zernecke-Madsen A, Schreiber LM (2018)
High-Resolution and Semidynamic Vessel Wall Imaging Kinetics obtained from Stable Radical MRI in ex-vivo Porcine Aorta.
European Journal of Heart Failure, 20:522-523.

Ramani-Mohan R-K, Schwedhelm I, Finne-Wistrand A, Krug M, Schwarz T, Jakob F, Walles H, Hansmann J (2018)
Deformation strain is the main physical driver for skeletal precursors to undergo osteogenesis in earlier stages of osteogenic cell maturation.
Journal of Tissue Engineering and Regenerative Medicine, 12(3):E1474-E1479.

Reuter C, Alzheimer M, Walles H, Oelschlaeger TA (2018)
An adherent mucus layer attenuates the genotoxic effect of colibactin.
Cellular Microbiology, 20(2).

Ribitsch I, Peham C, Ade N, Durr J, Handschuh S, Schramel JP, Vogl C, Walles H, Egerbacher M, Jenner F (2018)
Structure-Function relationships of equine menisci.
Plos One, 13(3).

Rosenbaum C, Boettner M, Wedel T, Metzger M (2018)
Laser-Capture Microdissection for Layer-Specific Analysis of Enteric Ganglia. In: Laser Capture Microdissection: Methods and Protocols, 3rd Edition.
Edited by Murray GI, vol. 1723; 361-369.

Schellenberger MT, Bock U, Hennen J, Groeber-Becker F, Walles H, Bloemeke B (2018) An in vitro coculture system composed of THP-1 cells and 3D reconstructed human epidermis to assess activation of dendritic cells by sensitizing chemicals.
N-S Arch Pharmacol, 391:S49-S49.

Schliermann A, Nickel J (2018)
Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling.
Int J Mol Sci, 19(10).

Schmid R, Tarau I-S, Rossi A, Leonhardt S, Schwarz T, Schuerlein S, Lotz C, Hansmann J (2018) 
In Vivo-Like Culture Conditions in a Bioreactor Facilitate Improved Tissue Quality in Corneal Storage.
Biotechnol J, 13(1).

Schmid FF, Groeber-Becker F, Schwab S, Thude S, Goebeler M, Walles H, Hansmann J (2018)
A Standardized Method Based on Pigmented Epidermal Models Evaluates Sensitivity Against UV-Irradiation.
Altex-Altern Anim Ex, 35(3):390-396.

Siverino C, Tabisz B, Luhmann T, Meinel L, Muller T, Walles H, Nickel J (2018)
Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry. J Vis Exp (133).

Steinke M, Zunhammer F, Chatzopoulou EI, Teller H, Schuetze K, Walles H, Raedler JO, Gruettner C (2018)
Rapid Analysis of Cell-Nanoparticle Interactions using Single-Cell Raman Trapping Microscopy.
Angewandte Chemie-International Edition 2018, 57(18):4946-4950.

Stuckensen K, Schwab A, Knauer M, Muinos-Lopez E, Ehlicke F, Reboredo J, Granero-Molto F, Gbureck U, Prosper F, Walles H et al (2018)
Tissue Mimicry in Morphology and Composition Promotes Hierarchical Matrix Remodeling of Invading Stem Cells in Osteochondral and Meniscus Scaffolds.
Advanced Materials, 30(28).

Suarez Munoz M, Confalonieri D, Walles H, van Dongen E, Dandekar G (2018) Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model. J Vis Exp (132).

Weigel T, Schmitz T, Pfister T, Gaetzner S, Jannasch M, Al-Hijailan R, Schuerlein S, Suliman S, Mustafa K, Hansmann J (2018)
A three-dimensional hybrid pacemaker electrode seamlessly integrates into engineered, functional human cardiac tissue in vitro.
Sci Rep-Uk, 8.


Appelt-Menzel A, Cubukova A, Neuhaus W, Piontek J, Walles H, Metzger M (2017) Establishment of a human blood-brain barrier co-culture model based on human multipotent and pluripotent stem cells mimicking the neurovascular unit.
Journal of Cerebral Blood Flow and Metabolism, 37:435-436.

Belka J, Weigel T, Berninger A-K, Kurth DG, Nickel J (2017)
Growth and Differentiation of Myoblastic Precursor Cells on Thin Films of Metallo-Supramolecular Coordination Polyelectrolyte (MEPE).
Advanced Materials Interfaces, 4(1).

Chen C-W, Thuong T-M, Lin N-Y, Zhang Y, Groeber F, Beyer C, Schett G, Distler J (2017) WNT5A Promotes Tissue Fibrosis By Wnt/PCP-Dependent Activation of Latent TGF-beta. Arthritis & Rheumatology, 69.

Christ B, Fey C, Cubukova A, Walles H, Dembski S, Metzger M (2017)
Screening Applications to Test Cellular Fitness in Transwell (R) Models After Nanoparticle Treatment.
In: Cell Viability Assays: Methods and Protocols. Edited by Gilbert DF, Friedrich O, vol. 1601; 111-122.

Confalonieri D, La Marca M, van Dongen EMWM, Walles H, Ehlicke F (2017)
An Injectable Recombinant Collagen I Peptide-Based Macroporous Microcarrier Allows Superior Expansion of C2C12 and Human Bone Marrow-Derived Mesenchymal Stromal Cells and Supports Deposition of Mineralized Matrix.
Tissue Eng Pt A, 23(17-18):946-957.

Egger D, Fischer M, Clementi A, Ribitsch V, Hansmann J, Kasper C (2017)
Development and Characterization of a Parallelizable Perfusion Bioreactor for 3D Cell Culture.
Bioengineering-Basel, 4(2).

Egger D, Schwedhelm I, Hansmann J, Kasper C (2017)
Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor.
Bioengineering-Basel, 4(2).

Engelhardt L, Groeber-Becker F, Hansmann J, Walles H (2017)
Impedance Spectroscopy as a New Tool to Monitor Reepithelialization in Wounded Reconstructed Human Epidermis.
Wound Repair Regen, 25(4):A17-A18.

Grabinger T, Bode KJ, Demgenski J, Seitz C, Delgado ME, Kostadinova F, Reinhold C, Etemadi N, Wilhelm S, Schweinlin M et al (2017)
Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells.
Gastroenterology, 152(4):867-879.

Jannasch M, Weigel T, Engelhardt L, Wiezoreck J, Gaetzner S, Walles H, Schmitz T, Hansmann J (2017) 
In Vitro Chemotaxis and Tissue Remodeling Assays Quantitatively Characterize Foreign Body Reaction.
Altex-Altern Anim Ex, 34(2):253-266.

Jannasch M, Gaetzner S, Weigel T, Walles H, Schmitz T, Hansmann J (2017)
A comparative multi-parametric in vitro model identifies the power of test conditions to predict the fibrotic tendency of a biomaterial.
Sci Rep, 7(1):1689.

Kremer A, Ribitsch I, Reboredo J, Durr J, Egerbacher M, Jenner F, Walles H (2017) Three-Dimensional Coculture of Meniscal Cells and Mesenchymal Stem Cells in Collagen Type I Hydrogel on a Small Intestinal Matrix-A Pilot Study Toward Equine Meniscus Tissue Engineering.
Tissue Eng Part A, 23(9-10):390-402.

Kunz M, Wolf B, Schulze H, Atlan D, Walles T, Walles H, Dandekar T (2017)
Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools.
Genes-Basel, 8(1).

Lagler C, El-Mesery M, Kubler AC, Muller-Richter UDA, Stuhmer T, Nickel J, Muller TD, Wajant H, Seher A (2017)
The anti-myeloma activity of bone morphogenetic protein 2 predominantly relies on the induction of growth arrest and is apoptosis-independent.
Plos One, 12(10):e0185720.

Lichter J, Bock U, Lotz C, Groeber F, Bloemeke B (2017)
Functional expression of N-acetyltransferase 1 in differentiated human skin keratinocytes.
British Journal of Dermatology, 177(3):870-872.

Lotz C, Schmid FF, Oechsle E, Monaghan MG, Walles H, Groeber-Becker F (2017)
Cross-linked Collagen Hydrogel Matrix Resisting Contraction To Facilitate Full-Thickness Skin Equivalents.
Acs Applied Materials and Interfaces, 9(24):20417-20425.

Massie I, Spaniol K, Barbian A, Poschmann G, Stuehler K, Geerling G, Metzger M, Mertsch S, Schrader S (2017) 
Evaluation of Decellularized Porcine Jejunum as a Matrix for Lacrimal Gland Reconstruction In Vitro for Treatment of Dry Eye Syndrome.
Investigative Ophthalmology and Visual Science, 58(12):5564-5574.

Muehlemann M, Zdzieblo D, Friedrich A, Hofmann M, Otto C, Koepsell H, Walles H, Metzger M (2017)
Enlarged islet size, altered insulin(+) and glucagon(+) cell frequencies and modified blood-values for GLP-1, insulin and glucagon in Sglt1 knockout mice.
Diabetologia, 60:S411-S412.

Pawelec KM, Confalonieri D, Ehlicke F, van Boxtel HA, Walles H, Kluijtmans S (2017) Osteogenesis and mineralization of mesenchymal stem cells in collagen type I-based recombinant peptide scaffolds.
J Biomed Mater Res A, 105(7):1856-1866.

Radakovic D, Reboredo J, Helm M, Weigel T, Schuerlein S, Kupczyk E, Leyh RG, Walles H, Hansmann J (2017)
A multilayered electrospun graft as vascular access for hemodialysis.
Plos One, 12(10).

Reuter C, Walles H, Groeber F (2017)
Preparation of a Three-Dimensional Full Thickness Skin Equivalent.
Methods Mol Biol, 1612:191-198.

Roedling L, Schwedhelm I, Kraus S, Bieback K, Hansmann J, Lee-Thedieck C (2017)
3D models of the hematopoietic stem cell niche under steady-state and active conditions.
Sci Rep-Uk, 7.

Schuerlein S, Schwarz T, Krziminski S, Gatzner S, Hoppensack A, Schwedhelm I, Schweinlin M, Walles H, Hansmann J (2017)
A versatile modular bioreactor platform for Tissue Engineering.
Biotechnol J, 12(2).

Schwab A, Meeuwsen A, Ehlicke F, Hansmann J, Mulder L, Smits A, Walles H, Kock L (2017)
Ex Vivo Culture Platform for Assessment of Cartilage Repair Treatment Strategies.
Altex-Altern Anim Ex, 34(2):267-277.

Schweinlin M, Rossi A, Lodes N, Lotz C, Hackenberg S, Steinke M, Walles H, Groeber F (2017)
Human barrier models for the in vitro assessment of drug delivery.
Drug Deliv Transl Re, 7(2):217-227.

Seher A, Lagler C, Stuehmer T, Mueller-Richter UDA, Kuebler AC, Sebald W, Mueller TD, Nickel J (2017)
Utilizing BMP-2 muteins for treatment of multiple myeloma.
Plos One, 12(5).

Strasser M, Schrauth JHX, Dembski S, Haddad D, Ahrens B, Schweizer S, Christ B, Cubukova A, Metzger M, Walles H et al (2017)
Calcium fluoride based multifunctional nanoparticles for multimodal imaging.
Beilstein J Nanotech, 8:1484-1493.

Tabisz B, Schmitz W, Schmitz M, Luehmann T, Heusler E, Rybak J-C, Meinel L, Fiebig JE, Mueller TD, Nickel J (2017)
Site-Directed Immobilization of BMP-2: Two Approaches for the Production of Innovative Osteoinductive Scaffolds.
Biomacromolecules, 18(3):695-708.

Tarau I-S, Schmid R, Lotz C, Rossi A, Schuerlein S, Walles H, Groeber-Becker F, Hansemann J, Hillenkamp J (2017)
Corneal woundhealing model employing a bioreactor.
Investigative Ophthalmology & Visual Science, 58(8).

Wunsch M, Jabari S, Voussen B, Enders M, Srinivasan S, Cossais F, Wedel T, Boettner M, Schwarz A, Weyer L et al (2017)
The enteric nervous system is a potential autoimmune target in multiple sclerosis.
Acta Neuropathologica, 134(2):281-295.


Anandarajah EM, Ditgen D, Hansmann J, Erttmann KD, Liebau E, Brattig NW (2016) SPARC (secreted protein acidic and rich in cysteine) of the intestinal nematode Strongyloides ratti is involved in mucosa-associated parasite-host interaction.
Molecular and Biochemical Parasitology, 207(2):75-83.

Baleeiro RB, Schweinlin M, Rietscher R, Diedrich A, Czaplewska JA, Metzger M, Lehr CM, Scherliess R, Hanefeld A, Gottschaldt M et al (2016)
Nanoparticle-Based Mucosal Vaccines Targeting Tumor-Associated Antigens to Human Dendritic Cells.
Journal of Biomedical Nanotechnology, 12(7):1527-1543.

Baur F, Dandekar G, Nietzer S, Walles H (2016)
Targeted therapies of two different Braf mutated colorectal carcinoma cell lines and the establishment of a 3D tumor model on the basis of a decellularized intestinal matrix. Oncology Research and Treatment, 39:72-72.

Brendtke R, Wiehl M, Groeber F, Schwarz T, Walles H, Hansmann J (2016)
Feasibility Study on a Microwave-Based Sensor for Measuring Hydration Level Using Human Skin Models.
Plos One, 11(4).

Dakhil H, Gilbert DF, Malhotra D, Limmer A, Engelhardt H, Amtmann A, Hansmann J, Huebner H, Buchholz R, Friedrich O et al (2016)
Measuring average rheological quantities of cell monolayers in the linear viscoelastic regime.
Rheologica Acta, 55(7):527-536.

Ditgen D, Anandarajah EM, Hansmann J, Winter D, Schramm G, Erttmann KD, Liebau E, Brattig NW (2016)
Multifunctional Thioredoxin-Like Protein from the Gastrointestinal Parasitic Nematodes Strongyloides ratti and Trichuris suis Affects Mucosal Homeostasis.
Journal of parasitology research, 2016:8421597-8421597.

Fecher D, Schwarz T, Nietzer S, Walles H, Dandekar G, Lueckerath K, Steinke M (2016) Development of a 3D organotypic lung tumor model in combination with FDG-PET to monitor treatment response.
Oncology Research and Treatment, 39:119-119.

Fecher D, Hofmann E, Buck A, Bundschuh R, Nietzer S, Dandekar G, Walles T, Walles H, Luckerath K, Steinke M (2016) Human Organotypic Lung Tumor Models: Suitable For Preclinical F-18-FDG PET-Imaging. Plos One, 11(8).

Goettlich C, Kunz M, Walles T, Walles H, Dandekar T, Dandekar G, Nietzer S (2016) Individualized drug response predictions based on a combined in silico and in vitro lung cancer model on a biological scaffold.
Oncology Research and Treatment, 39:26-27.

Goettlich C, Mueller LC, Kunz M, Schmitt F, Walles H, Walles T, Dandekar T, Dandekar G, Nietzer SL (2016)
A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds.
Jove-J Vis Exp (110).

Groeber FK, Engelhardt L, Le Varlet B, De Wever B, Walles H, Hansmann J (2016) Complex skin models and impedance spectroscopy as new tools for dermatological research.
Journal of Investigative Dermatology, 136(9):S255-S255.

Groeber F, Schober L, Schmid FF, Traube A, Kolbus-Hernandez S, Daton K, Hoffmann S, Petersohn D, Schaefer-Korting M, Walles H et al (2016)
Catch-up validation study of an in vitro skin irritation test method based on an open source reconstructed epidermis (phase II).
Toxicol in Vitro, 36:254-261.

Groeber F, Engelhardt L, Lange J, Kurdyn S, Schmid FF, Ruecker C, Mielke S, Walles H, Hansmann J (2016)
A First Vascularized Skin Equivalent as an Alternative to Animal Experimentation.
Altex-Altern Anim Ex, 33(4):415-422.

Kunz M, Wolf B, Schulze H, Atlan D, Walles T, Walles H, Dandekar T (2016)
Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools.
Genes (Basel), 8(1).

Lange J, Weil F, Riegler C, Groeber F, Rebhan S, Kurdyn S, Alb M, Kneitz H, Gelbrich G, Walles H et al (2016)
Interactions of donor sources and media influence the histo-morphological quality of full-thickness skin models.
Biotechnol J, 11(10):1352-1361.

Lotz C, Schmid FF, Rossi A, Kurdyn S, Kampik D, De Wever B, Walles H, Groeber FK (2016)
Alternative Methods for the Replacement of Eye Irritation Testing.
Altex-Altern Anim Ex, 33(1):55-67.

Massie I, Spaniol K, Geerling G, Metzger M, Schrader S (2016)
Formation of functionally competent 3D lacrimal gland cell spheroids - towards regeneration of lacrimal gland tissue.
Investigative Ophthalmology & Visual Science, 57(12).

Mueller L, Walles H, Nietzeri S, Dandekar G (2016)
Establishment and characterization of a 3D mamma carcinoma test system on a decellularized scaffold.
Oncology Research and Treatment, 39:2-2.

Nietzer S, Baur F, Sieber S, Hansmann J, Schwarz T, Stoffer C, Haefner H, Gasser M, Waaga-Gasser AM, Walles H et al (2016)
Mimicking Metastases Including Tumor Stroma: A New Technique to Generate a Three-Dimensional Colorectal Cancer Model Based on a Biological Decellularized Intestinal Scaffold.
Tissue Engineering Part C-Methods, 22(7):621-635.

Reboredo JW, Weigel T, Steinert A, Rackwitz L, Rudert M, Walles H (2016)
Investigation of Migration and Differentiation of Human Mesenchymal Stem Cells on Five-Layered Collagenous Electrospun Scaffold Mimicking Native Cartilage Structure.
Adv Healthc Mater, 5(17):2191-2198.

Rosenbaum C, Schick MA, Wollborn J, Heider A, Scholz CJ, Cecil A, Niesler B, Hirrlinger J, Walles H, Metzger M (2016)
Activation of Myenteric Glia during Acute Inflammation In Vitro and In Vivo.
Plos One, 11(3).

Schweinlin M, Wilhelm S, Schwedhelm I, Hansmann J, Rietscher R, Jurowich C, Walles H, Metzger M (2016)
Development of an Advanced Primary Human In Vitro Model of the Small Intestine. Tissue Engineering Part C-Methods, 22(9):873-883.

Suliman S, Sun Y, Pedersen TO, Xue Y, Nickel J, Waag T, Finne-Wistrand A, Steinmueller-Nethl D, Krueger A, Costea DE et al (2016)
In Vivo Host Response and Degradation of Copolymer Scaffolds Functionalized with Nanodiamonds and Bone Morphogenetic Protein 2.
Advanced Healthcare Materials, 5(6):730-742.

Suliman S, Mustafa K, Krueger A, Steinmueller-Nethl D, Finne-Wistrand A, Osdal T, Hamza AO, Sun Y, Parajuli H, Waag T et al (2016)
Nanodiamond modified copolymer scaffolds affects tumour progression of early neoplastic oral keratinocytes.
Biomaterials, 95:11-21.


Delling U, Brehm W, Metzger M, Ludewig E, Winter K, Juelke H (2015)
In Vivo Tracking and Fate of Intra-Articularly Injected Superparamagnetic Iron Oxide Particle-Labeled Multipotent Stromal Cells in an Ovine Model of Osteoarthritis.
Cell Transplantation, 24(11):2379-2390.

Fecher D, Dandekar G, Nietzer S, Bundschuh RA, Walles H, Buck AK, Steinke M, Lueckerath K (2015)
mu PET as non-invasive read-out for a novel human organotypic lung tumor model. European Journal of Nuclear Medicine and Molecular Imaging, 42:S427-S428.

Goettlich C, Nietzer S, Dandekar G, Walles H (2015)
A 3D Human Lung Tumor Test System on an Acellular Scaffold: Simulation of a Biomarker-guided Therapy.
Tissue Eng Pt A, 21:S204-S204.

Gordon S, Daneshian M, Bouwstra J, Caloni F, Constant S, Davies DE, Dandekar G, Guzman CA, Fabian E, Haltner E et al (2015)
Non-Animal Models of Epithelial Barriers (Skin, Intestine and Lung) in Research, Industrial Applications and Regulatory Toxicology.
Altex-Altern Anim Ex, 32(4):327-378.

Groeber F, Engelhardt L, Egger S, Werthmann H, Monaghan M, Walles H, Hansmann J (2015)
Impedance Spectroscopy for the Non-Destructive Evaluation of In Vitro Epidermal Models.
Pharm Res-Dordr, 32(5):1845-1854.

Hinderer S, Shen N, Ringuette L-J, Hansmann J, Reinhardt DP, Brucker SY, Davis EC, Schenke-Layland K (2015)
In vitro elastogenesis: instructing human vascular smooth muscle cells to generate an elastic fiber-containing extracellular matrix scaffold.
Biomedical Materials, 10(3).

Jannasch M, Groeber F, Brattig NW, Unger C, Walles H, Hansmann J (2015)
Development and application of three-dimensional skin equivalents for the investigation of percutaneous worm invasion.
Exp Parasitol, 150:22-30.

Klammert U, Mueller TD, Hellmann TV, Wuerzler KK, Kotzsch A, Schliermann A, Schmitz W, Kuebler AC, Sebald W, Nickel J (2015)
GDF-5 can act as a context-dependent BMP-2 antagonist.
BMC Biol, 13:77.

Kleinhans C, Mohan RR, Vacun G, Schwarz T, Haller B, Sun Y, Kahlig A, Kluger P, Finne-Wistrand A, Walles H et al (2015)
A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects.
Biotechnol J, 10(11):1727-1738.

Luehmann T, Jones G, Gutmann M, Rybak J-C, Nickel J, Rubini M, Meinel L (2015)
Bio-orthogonal Immobilization of Fibroblast Growth Factor 2 for Spatial Controlled Cell Proliferation.
Acs Biomaterials Science & Engineering, 1(9):740-746.

Meir M, Flemming S, Burkard N, Bergauer L, Metzger M, Germer C-T, Schlegel N (2015)
Glial cell line-derived neurotrophic factor promotes barrier maturation and wound healing in intestinal epithelial cells in vitro.
American Journal of Physiology-Gastrointestinal and Liver Physiology, 309(8):G613-G624.

Munoz MS, Dandekar G, Walles H (2015)
Study of the Effect of Collagenous Microcarriers on the Vasculogenic Potential of Endothelial Cells Obtained from Different Sources.
Tissue Eng Pt A, 21:S107-S107.

Ramachandran SD, Vivares A, Klieber S, Hewitt NJ, Muenst B, Heinz S, Walles H, Braspenning J (2015) 
Applicability of second-generation upcyte(R) human hepatocytes for use in CYP inhibition and induction studies.
Pharmacol Res Perspect, 3(5):e00161.

Ramachandran SD, Schirmer K, Munst B, Heinz S, Ghafoory S, Wolfl S, Simon-Keller K, Marx A, Oie CI, Ebert MP et al (2015)
In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells.
Plos One, 10(10):e0139345.

Rossi A, Appelt-Menzel A, Kurdyn S, Walles H, Groeber F (2015)
Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding.
Jove-J Vis Exp (96).

Rossi A, Appelt-Menzel A, Kurdyn S, Walles H, Groeber F (2015)
Generation of a three-dimensional full thickness skin equivalent and automated wounding.
J Vis Exp (96)

Schwab A, Ehlicke F, Reboredo J, Hansmann J, Walles H: (2015)
Ex Vivo Osteo-chondral Organ Culture.
Tissue Eng Pt A, 21:S304-S305.

Schweinlin M, Wilhelm S, Walles H, Metzger M (2015)
Development of an Improved Primary in vitro Model of the Human Small Intestine. Tissue Eng Pt A, 21:S302-S303.

Siverino C, Nickel J, Walles H (2015)
Site-directed Immobilization of BMP-2 and Noggin Inhibitory Peptides onto Collagen Beads for Bone Regeneration.
Tissue Eng Pt A, 21:S118-S119.

Spaniol K, Metzger M, Roth M, Greve B, Mertsch S, Geerling G, Schrader S (2015) Engineering of a Secretory Active Three-Dimensional Lacrimal Gland Construct on the Basis of Decellularized Lacrimal Gland Tissue.
Tissue Eng Pt A, 21(19-20):2605-2617.

Suliman S, Xing Z, Wu X, Xue Y, Pedersen TO, Sun Y, Doskeland AP, Nickel J, Waag T, Lygre H et al (2015)
Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo.
Journal of Controlled Release, 197:148-157.

Walles H, Steinke M, Ruecker C, Hansmann J, Groeber F, Blunk T, Metzger M, Dandekar G, Pullig O (2015)
Biovasc-term (R): A Platform Technology to Engineer of Vascularised Human Tissues. Tissue Eng Pt A, 21:S247-S247.


Baur F, Sieber S, Dandekar G, Nietzer S, Walles H (2014)
Targeted therapies of two different braf mutated cell lines and the establishment of a 3D tumor model on the basis of a decellularized intestinal matrix.
Oncology Research and Treatment, 37:43-43.

Bersi H, Nietzer S, Dandekar G, Walles H (2014)
Establishment of a human 3D blood vessel model for testing therapeutic agents such as tipifarnib in AML.
Oncology Research and Treatment, 37:85-85.

Fecher D, Walles H, Nietzer S, Dandekar G (2014)
Establishment of a 3D Lung Tumor Model and Adjustment to Lung Specific Conditions.
Oncology Research and Treatment, 37:88-89.

Goettlich C, Fecher D, Nietzer S, Dandekar G, Walles H (2014)
Validation of a three-dimensional human lung tumor test system applied for the analysis of targeted treatment effects on signaling pathway activation.
Oncology Research and Treatment, 37:90-90.

Heinlein A, Metzger M, Walles H, Buettner A (2014) 
Transport of hop aroma compounds across Caco-2 monolayers.
Food & Function, 5(11):2719-2730.

Hetz S, Acikgoez A, Voss U, Nieber K, Holland H, Hegewald C, Till H, Metzger R, Metzger M (2014)
In Vivo Transplantation of Neurosphere-Like Bodies Derived from the Human Postnatal and Adult Enteric Nervous System: A Pilot Study.
Plos One, 9(4).

Hetz S, Acikgoez A, Moll C, Jahnke H-G, Robitzki AA, Metzger R, Metzger M (2014)
Age-related gene expression analysis in enteric ganglia of human colon after laser microdissection.
Frontiers in Aging Neuroscience, 6.

Hinderer S, Shen N, Ringuette L-J, Hansmann J, Reinhardt D, Elaine D, Schenke-Layland K (2014)
In vitro elastogenesis.
Faseb Journal, 28(1).

Kress S, Nickel J, Walles H (2014)
Generation of a miniaturized biologically vascularized scaffold for 3D tissue culture. Journal of Tissue Engineering and Regenerative Medicine, 8:182-182.

Markenstein L, Appelt-Menzel A, Metzger M, Wenz G (2014)
Conjugates of methylated cyclodextrin derivatives and hydroxyethyl starch (HES): Synthesis, cytotoxicity and inclusion of anaesthetic actives.
Beilstein Journal of Organic Chemistry, 10:3087-3096.

Moll C, Heider A, Brede C, Scholz CJ, Cecil A, Walles H, Metzger M (2014)
The role of enteric glial cells in inflammatory diseases of the bowel. Neurogastroenterology and Motility, 26:35-35.

Stratmann AT, Fecher D, Wangorsch G, Goettlich C, Walles T, Walles H, Dandekar T, Dandekar G, Nietzer SL (2014)
Establishment of a human 3D lung cancer model based on a biological tissue matrix combined with a Boolean in silico model.
Mol Oncol, 8(2):351-365.

Zeplin PH, Maksimovikj NC, Jordan MC, Nickel J, Lang G, Leimer AH, Roemer L, Scheibel T (2014)
Spider Silk Coatings as a Bioshield to Reduce Periprosthetic Fibrous Capsule Formation. Advanced Functional Materials, 24(18):2658-2666.


Portraitfoto von PD Dr. Marco Metzger

PD Dr.
Marco Metzger

Stellvertretende Kommissarische Leitung

+49 931 31-86686

Portraitfoto von Dr. Joachim Nickel

Joachim Nickel

Stellvertrende Kommissarische Leitung, Gruppenleitung

+49 931 31-84122



Anna Stefl
+49 931 31-80183


+49 931 31-81068


Lehrstuhl für Tissue Engineering und Regenerative Medizin (TERM) | Röntgenring 11 | 97070 Würzburg | Deutschland