Abteilung für klinische Studien der Neurologischen Klinik (August 2023)

Bewegungsstörungen (Morbus Parkinson / Dystonien / Tremor-Erkrankungen /Chorea / Botulinumtoxin-Therapie / THS)

Enroll-HD: A prospective Registry Study in a Global Huntington’s Disease Cohort. Observational, prospective, multinational, multi-centre study without experimental treatment.

Eudra-CT: 2016-001378-13 / StimTox: A randomized, sham-controlled trial of pallidal neurostimulation versus botulinum toxine treatment for cervical dystonia.

EudraCT: 2018-001639-35 / PATTERN: Prospective, randomized, double-blind, placebo-controlled, multicenter study to investigate the efficacy and safety of NT 201 in the treatment of lower limb spasticity caused by stroke or traumatic brain injury in adult subjects, followed by an open label extension with or without combined upper limb treatment. PATTERN (Merz). Protocol Code: M602011014. Phase 3. 

Eudra-CT: 2021-003879-34 / ROCK-PD: Phase IIa. Multi-center, prospective,interventional, randomized, double-blind, placebo-controlled, parallel-group, non-inferiority. Safety, Tolerability and Symptomatic Efficacy of the ROCK-Inhibitor Fasudil in Patients with Parkinson’s Disease.

Eudra-CT: 2021-004849-20 / 283PD201 LUMA Study: A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of BIIB122 in Participants with Parkinson’s Disease.

VERCISE DBS PD: Registry of Deep Brain Stimulation with the VERCISE™ System (Vercise DBS Registry). A prospective, on-label, multi-center, international Registry. 

VERCISE Dystonia: Registry of Deep Brain Stimulation with the VERCISE™ System for treatment of Dystonia: Vercise DBS Dystonia Registry. A prospective, on-label, multi-center, international Registry. 

DysTract: Deutsches Netzwerk zur translationalen Erforschung und Behandlung dystoner Erkrankungen. DysTract - Eine multizentrische Registerstudie. 

RETRO DBS: Retrospective, multi-center, data review. Deep Brain Stimulation Retrospective Outcomes Study A4170 
(DBS RETRO). The primary objective of this study is to characterize real-world clinical outcomes of Deep Brain Stimulation (DBS) using retrospective review of de-identified patient records. 

STEEROPT: Can subthalamic stimulation using directional electrodes improve postoperative management in Parkinson’s disease? A post-market study.

The Essential Tremor Registry: Study Reference Number: A4080. Boston Scientific Registry of Deep Brain Stimulations for treatment of Essential Tremor (ET). 

EFRONT: Epidemiological Study in Frontotemporal Dementia. An international, multicentre, epidemiological observational Study. 

DIPS: Bildgebungsunterstützte Programmierung der Tiefen Hirnstimulation im internen Globus pallidus bei Dystonie-Patienten

ReTune: Zentrale Datenbank des Projektes INF des Collaborative Research Centre (CRC/TRR295) zur Erfassung klinischer Kerndaten 

Entzündliche Erkrankungen des ZNS (Autoimmunerkrankungen / MS / Neurosarkoidose)

Eudra-CT: 2019-001423-12 / GENERATE-BOOST: Multizentrische, randomisierte, kontrollierte und doppelblinde Studie zur Überprüfung der Wirksamkeit und Sicherheit von Bortezomib bei Patienten mit schwerer autoimmuner Enzephalitis.

MoOzart: Protocol Number: ML42393. Impact of Ocrelizumab on Patient Reported Fatigue and Quality of Life in RMS Patients treated for the first time with Ocrelizumab (Moozart).

Schlaganfall und Gefäßerkrankungen

EudraCT: 2018-002176-41 / PRESTIGE-AF: PREvention of Stroke in Intracerebral haemorrhaGesurvivors with Atrial Fibrillation. Schlaganfallvorbeugung bei Patienten mit intracerebraler Blutung und Vorhofflimmern. 

Eudra-CT: 2015-004505-16 / CONVINCE: CON-001: COIchincine for preventioN of Vascular Inflammatoin in Non-CardioEmbolic Stroke – a randomized clinical trial of low-dose colchicine for secondary prevention after stroke. 

ODEA-TIA: Optimal Detection of Atrial fibrillation in Transient Ischemic Attack 

FIND-AF 2 study: Intensive heart rhythm monitoring to decrease ischemic stroke and systemic embolism

CAEHR Project: Herzkreislauferkrankungen – Verbesserung der Gesundheitsversorgung durch sektorenübergreifende Integration von Routinedaten

ESCAPE-MeVO: A Multicenter, Prospective, Randomized, Parallel Group, Open-label Design to Determine the Efficacy and Safety of Endovascular Thrombectomy for ischemic stroke patients with symptomatic Acute Medium Vessel Intracranial Occlusions

Epilepsie

ToSEE: Treatment of Established Status Epilepticus in the Elderly – a prospective, randomized, double-blind comparative effectiveness trial 

Neuromuskuläre Erkrankungen (Myopathien / PNP / Motoneuron-Erkrankungen)

EudraCT: 2019-004256-11 / MT-1186-A02: A Phase 3b, Multicenter, Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Oral Edaravone Administered for a Period of 48 Weeks in Subjects with Amyotrophic Lateral Sclerosis (ALS). 

Eudra-CT: 2021-003900-42 / MT-1186-A04: A Phase 3b, multicenter, randomized, double-blind Extension Study to Evaluate the continued Efficacy and Safety of Oral Edaravone administered for an additional period of up to 48 weeks following Study MT-1186-A02 in Subjects with Amyotrophic Lateral Sclerosis (ALS). 

SMArtCARE: Longitudinal Data Collection from Patients with Spinal Muscular Atrophy 

Detailliert informieren wir Sie gern im Rahmen unserer Spezialambulanzen über die entsprechenden Studien.

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Direktion

Prof. Dr. Jens Volkmann
E-Mail: nl_direktion@ ukw.de

Sekretariat
Frederike Wende
Telefon: +49 931 201-23751
E-Mail: wende_f@ ukw.de

Oberarztsekretariat

Melissa Fritsch
Telefon: +49 931 201-23756
E-Mail: fritsch_m@ ukw.de 

Oberarztsekretariat / Studierendenangelegenheiten

Cornelia Seiler
Telefon: +49 931 201-23754
E-Mail: seiler_c3@ ukw.de

 


Anschrift

Neurologische Klinik und Poliklinik des Universitätsklinikums | Kopfkliniken | Josef-Schneider-Straße 11 | Haus B1 | 97080 Würzburg