Publikationen Neonatologie

2017

Andres O, Henning K, Strauß G, Pflug A, Manukjan G, Schulze H. (2017) Diagnosis of platelet function disorders: A standardized, rational, and modular flow cytometric approach. Platelets 11:1-10. doi: 10.1080/09537104.2017.

Andres O, Wiegering V, König EM, Schneider AL, Semeniak D, Stritt S, Klopocki E, Schulze H. (2017) A novel two-nucleotide deletion in HPS6 affects mepacrine uptake and platelet dense granule secretion in a family with Hermansky-Pudlak syndrome. Pediatr Blood Cancer 64(5). doi: 10.1002/pbc.26320.

Belling-Dierks F, Glaser K, Wirbelauer J, Rücker V, Frieauff E. (2017) Does rapid enteral feeding increase intestinal morbidity in very low birth weight infants? A retrospective analysis. J Matern Fetal Neonatal Med. 30:2690-2696.

De la Haye N, Hütten MC, Kunzmann S, Kramer BW. (2017) Bronchopulmonary Dysplasia and Ureaplasma: What do we know so far? Neonatal Med 24:1-6.

Fehrholz M, Glaser K, Speer CP, Seidenspinner S, Ottensmeier B, Kunzmann S. (2017) Caffeine modulates glucocorticoid-induced expression of ctgf in lung epithelial cells and fibroblasts. Respir Res 18:51.

Fehrholz M, Seidenspinner S, Kunzmann S. (2017) Expression of surfactant protein B is dependent on cell density in H441 lung epithelial cells. PLoS One 12:e0184556.

Glaser K, Fehrholz M, Henrich B, Claus H, Papsdorf M, Speer CP. (2017) Anti-inflammatory effects of the new generation synthetic surfactant CHF5633 on Ureaplasma-induced cytokine responses in human monocytes. Expert Rev Anti Infect Ther 15:181-189.

Glaser K, Silwedel C, Fehrholz M, Waaga-Gasser AM, Henrich B, Claus H, Speer CP. (2017) Ureaplasma species differentially modulate pro- and anti-inflammatory cytokine responses in newborn and adult human monocytes pushing the state toward pro-inflammation. Front Cell Infect Microbiol 7:484.

Haug V, Benoit S, Wohlleben M, Hamm H. (2017) Annular pustular psoriasis in a 14-month-old girl: a therapeutic challenge. J Dermatol Treatm 28:520-522.

Klotz D, Schönlaub J, Hackenberg S, Wirbelauer J. (2017) Severe Respiratory Distress in a Neonate due to Bilateral Dacryocystoceles. Pediatr Emerg Care 33:489 doi: 10.1097/PEC.0000000000000577.

Kredel M, Kunzmann S, Schlegel PG, Wölfl M, Nordbeck P, Bühler C, Lotz C, Lepper PM, Wirbelauer J, Roewer N, Muellenbach RM (2017): Double Peripheral Venous and Arterial Cannulation for Extracorporeal Membrane Oxygenation in Combined Septic and Cardiogenic Shock. Am J Case Rep 28:723-727.

Loewecke F, Andres O, Eber SW. (2017) Anämiediagnostik. Alte und neue Parameter. Kinder- und Jugendmedizin 17:93-104.

Molloy EJ, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP. (2017) Sharing Progress in Neonatal (SPIN) Brain, Gut, Heart, and Lung. Neonatology 111:384-387.

Schönfelder SM, Dong Y, Feßler AT, Schwarz S, Schön C, Köck R, Ziebuhr W. (2017) Antibiotic resistance profiles of coagulase-negative staphylococci in livestock einvironments. Vet Microbiol 200:79-87.

Schulze H, Schlagenhauf A, Manukjan G, Beham-Schmid C, Andres O, Klopocki E, König EM, Haidl H, Panzer S, Althaus K, Muntean WE, Schwinger W, Urban C, Greinacher A, Bakchoul T, Seidel MG. (2017) Recessive grey platelet-like syndrome with unaffected erythropoiesis in the absence of the splice isoform GFI1B-p37. Haematologica 102:e375-e378. doi: 10.3324/haematol.2017.

Seefried L, Baumann J, Hemsley S, Hofmann C, Kunstmann E, Kiese B, Huang Y, Chivers S, Valentin M-A, Borah B, Roubenoff R, Junker U, Jakob F. (2017) Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia. J Clin Invest doi.org/10.1172/JCI83731.

Silwedel C, Frieauff E,  Thomas W, Liese JG, Speer CP. (2017) Secondary haemophagocytic lymphohistiocytosis triggered by postnatally acquired cytomegalovirus infection in a late preterm infant. Infection DOI 10.1007/s15010-016-0970-3.

Silwedel C, Speer CP, Glaser K. (2017) Ureaplasma-associated prenatal, perinatal, and neonatal morbidities. Expert Rev Clin Immunol 23:1-15 DOI 10.1080/1744666X.2017.

Speer CP, Halliday HL. (2017) Bo Sun and the Development of Neonatology in China. Neonatology 112:288-290.

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka, R, Saugstad OD, Simeoni U, Speer CP, Vento M, Visser GHA, Halliday HL. (2017) European consensus guidelines on the management of respiratory distress syndrome – 2016 update. Neonatology 111:107-125.

Sweet DG, Turner M, Stranak Z, Plavka R, Clarke P, Stenson B, Singer D, Goelz R, Fabbri L, Varoli G, Piccinno A, Santoro D, Speer CP. (2017) A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF 5633) in preterm babies with respiratory distress syndrome. Arch Dis Child Fetal Neonatal Ed 102:F497-F503. doi: 10.1136/archdischild-2017-312722.

Wiedemann K, Stüber T, Rehn M, Frieauff E. (2017) Fetal Valproate Syndrome - Still a Problem Today! Z Geburtsh Neonatol 221:243-24.

2016

Belling-Dierks F, Glaser K, Wirbelauer J, Rücker V, Frieauff E. (2016) Does rapid enteral feeding increase intestinal morbidity in very low birth weight infants? A retrospective analysis. J Matern Fetal Neonatal Med 15:1-18.

Braun M, Siauw C, Schirrmeister J, Wirbelauer J. (2016) Perinatal Presentation and Complicated Course of a Multifocal Atrial Tachycardia. Z Geburtshilfe Neonatol 220(6):265-268.

Buonocore G, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP. (2016) Sharing Progress in Neonatal (SPIN) Lung and Brain. Neonatology 109(4):322-4.

Fehrholz M, Glaser K, Seidenspinner S, Ottensmeier B, Curstedt T, Speer CP, Kunzmann S. (2016) Impact of the New Generation Reconstituted Surfactant CHF5633 on Human CD4+ Lymphocytes. PLoS One 11(4):e0153578.

Glaser K, Fehrholz M, Curstedt T, Kunzmann S, Speer CP. (2016) Effects of the New Generation Synthetic Reconstituted Surfactant CHF5633 on Pro- and Anti-Inflammatory Cytokine Expression in Native and LPS-Stimulated Adult CD14+ Monocytes. PLoS One 11(1):e0146898.

Glaser K, Fehrholz M, Henrich B, Claus H, Papsdorf M, Speer CP. (2016) Anti-inflammatory effects of the new generation synthetic surfactant CHF5633 on Ureaplasma-induced cytokine responses in human monocytes. Expert Rev Anti Infect Ther 18:1-9.

Glaser K, Fehrholz M, Papsdorf M, Curstedt T, Kunzmann S, Speer CP. (2016) The new generation synthetic reconstituted surfactant CHF5633 suppresses LPS-induced cytokine responses in human neonatal monocytes. Cytokine 86:119-23.

Neubauer H, Kunzmann S, Wirbelauer J. (2016) Kongenitaler extrahepatischer portosystemischer Shunt (CEPS) Abernethy II bei einem Frühgeborenen mit Noonan-Syndrom. Rofo 188(7):685-7.

Ruf K, Hackenberg S, Kraus F, Wirbelauer J, Frieauff E, Hagen R, Kunzmann S. (2016) Carbon Dioxide Laser Cordotomy as Possible Alternative for Tracheotomy in a Neonate with Idiopathic Bilateral Vocal Fold Paralysis. Klin Padiatr. 228(4):213-5.

Schönfelder SM, Dong Y, Feßler AT, Schwarz S, Schön C, Köck R, Ziebuhr W. (2016) Antibiotic resistance profiles of coagulase-negative staphylococci in livestock environments. Vet Microbiol pii: S0378-1135(16)30102-X.

Segerer FJ, Speer CP. (2016) Lung Function in Childhood and Adolescence: Influence of Prematurity and Bronchopulmonary Dysplasia. Z Geburtsh Neonatol 220(4):147-54.

Silwedel C, Kunzmann S, Meyer T, Rauthe S, Frieauff E. (2016) Seltene Ursache eines akuten Abdomens beim Frühgeborenen. Monatsschr Kinderheilkd. 2016;164(1): 7-9.

Silwedel C, Vogel U, Claus H, Glaser K, Speer CP, Wirbelauer J. (2016) Outbreak of multidrug-resistant Escherichia coli sequence type 131 in a neonatal intensive care unit: efficient active surveillance prevented fatal outcome. J Hosp Infect pii:S0195-6701(16)00134-1.

Stüber TN, Frieauff E, Weiß C, Zollner U, Wöckel A, Meyer T, Rehn M. (2016) Prenatal sonographic ultrasound predictors for the outcome in fetal gastroschisis: a retrospective analysis. Arch Gynecol Obstet. 2016;293(5): 1001-6.

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Vento M, Visser GH, Halliday HL. (2016) European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2016 Update. Neonatology 111(2):107-125.

Wiedemann K, Schmid C, Hamm H, Wirbelauer J. (2016) Staphylococcal Scalded Skin Syndrome in a Very Low Birth Weight Premature Infant. Z Geburtshilfe Neonatol, 220(1):35-8.

Wiewrodt B, Dittrich S, Uder M, Wirbelauer J. (2016) Transcatheter Intervention of Bilateral Renal Artery Stenosis in an Infant after Transposition of the Great Arteries. Klin Padiatr, 228(2):94-5.

2015

Andres O, Eber S, Speer CP. (2015) Early postnatal diagnosis of hereditary spherocytosis by combining light microscopy, acidified glycerol lysis test and eosin-5’-maleimide binding assay. Ann Hematol 94(12):1959-64.

Andres O, Schulze H, Speer CP. (2015) Platelets in neonates: central mediators in haemostasis, antimicrobial defence and inflammation. Thromb Haemost 113(1):3-12.

Bersani I, De Carolis MP, Foell D, Weinhage T, Rossi ED, De Carolis S, Rubortone SA, Romagnoli C, Speer CP. (2015) Interleukin-22: biomarker of maternal and fetal inflammation? Immunol Res. 2015 Feb;61(1-2):4-10.

Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP. (2015) 30 years of surfactant research – from basic science to new clinical treatments for the preterm infant. Neonatology 107:314-6.

Curstedt T, Halliday HL, Speer CP. (2015) A unique story in neonatal research: The development of a porcine surfactant. Neonatology 107:321-9.

Dong Y, Speer CP. (2015) Late-onset neonatal sepsis: the recent development. Arch Dis Child Fetal Neonatal Ed 100(3):F257–F263.

Frauenschuh I, Wirbelauer J, Karl S, Girschick G, Rehn M, Zollner U, Frambach T, Dietl J, Müller T. (2015) Prognostic factors of perinatal short-term outcome in severe placental insufficiency using doppler sonography to assess end-diastolic absent and reverse blood flow in umbilical arteries. Z Geburtshilfe Neonatol. 219(1): 28-36.

Glaser K, Girschick HJ, Schropp C, Speer CP. (2015) Psychomotor development following early treatment of severe infantile vitamin B12 deficiency and West syndrome--is everything fine? A case report and review of literature. Brain Dev 37(3):347-51.

Glaser K, Fehrholz M, Curstedt T, Kunzmann S,  Speer CP. (2015) Effects of the New Generation Synthetic Reconstituted Surfactant CHF5633 on Pro- and Anti-Inflammatory Cytokine Expression in Native and LPS-Stimulated Adult CD14+ Monocytes.   PLoS ONE 11(1): e0146898.

Glaser K, Fehrholz M, Seidenspinner S, Ottensmeier B, Wollny B, Kunzmann S. (2015) Pitfalls in flow cytometric analyses of surfactant-exposed human leukocytes. Immunol Lett. 12;166(1):19-27.

Glaser K, Speer CP. (2015) Neonatal CNS infection and inflammation caused by ureaplasma species: rare or relevant? Expert Rev Anti Infect Ther 13(2):233-48.

Glaser K, Wohlleben M, Speer CP (2015): An 8-month history of meningitis in an extremely low birth weight infant? - Long-lasting Infection with Ureaplasma parvum. Z Geburtshilfe Neonatol. 219(1): 52-6.

Linz C, Collmann H, Meyer-Marcotty P, Böhm H, Krauß J, Müller-Richter UD, Ernestus RI, Wirbelauer J, Kübler AC, Schweitzer T. (2015) Occipital plagiocephaly: unilateral lambdoid synostosis versus positional plagiocephaly. Arch Dis Child. 100(2): 152-7.

Loeffler C, Loeffler J, Kobsar A, Speer CP, Eigenthaler M. (2015) Septic vs colonizing group B Streptococci differentially regulate inflammation and apoptosis in human coronary artery endothelial cells – a pilot study. Pediatr Neonatal Care 2:00064.

Mall M, Wirbelauer J. (2015) Blickdiagnose: Tachykardie des  Neugeborenen. Bay. Ärzteblatt.

Müller T, Wirbelauer J, Frauenschuh I, Frambach T, Zollner U, Dietl J. (2015) Umbilical absent and reverse end-diastolic flow velocity waveforms already present prior to viability do not exclude long-term foetal surveillance: A report of two cases. Z Geburtsh Neonatol 219(2): 99-101.

Neuhaus W, Schlundt M, Fehrholz M, Ehrke A, Kunzmann S, Liebner S, Speer CP, Förster CY. (2015) Multiple antenatal dexamethasone treatment alters brain vessel differentiation in newborn mouse pups. PLoS One 10:e0136221.

Schmid C, Wiedemann K, Hamm H, Wirbelauer J. (2015) Dermatitis exfoliativa (Staphylococcal Scalded Skin Syndrome) bei einem sehr unreifen Frühgeborenen.  Diaklinik 48. Tagung der Deutschen Dermatologischen Gesellschaft. freeLINE, Eching.

Schröder D, Rehn M, Wirbelauer J. (2015) Fetale Bradykardie mit genetischem Hintergrund. Differentialdiagnose einer fetalen Bradyarrhythmie. Z Geburtshilfe Neonatol 219(1): 8-10.

Siauw C, Wirbelauer J, Schweitzer T, Speer CP. (2015) Late Vitamin K Deficient Bleeding in 2 Young Infants - Renaissance of a Preventable Disease. Z Geburtshilfe Neonatol. 219(5):238-24.

2014

Bersani I, De Carolis MP, Foell D, Weinhage T, Rossi ED, De Carolis S, Rubortone SA, Romagnoli C, Speer CP. (2014) Interleukin-22: Biomarker of maternal and fetal inflammation? Immunol Res. 2014 Nov 19. Epub ahead of print.

Dong Y, Speer CP. (2014) The role of Staphylococcus epidermidis in neonatal sepsis: Guarding angel or pathogenic devil? Int J Med Microbiol 304:513-520.

Dong Y, Speer CP. (2014) Late-onset neonatal sepsis: the recent development. Arch Dis Child pii: fetalneonatal-2014-306213. doi: 10.1136/archdischild-2014-306213.

Fehrholz M, Hütten M, Kramer BW, Speer CP, Kunzmann S. (2014) Amplification of steroid-mediated SP-B expression by physiological levels of caffeine. Am J Physiol Lung Cell Mol Physiol; 306:L101-109.

Fehrholz M, Kunzmann S, Speer CP. (2014) Ambivalent Role of ErbB4 during Induction of Surfactant Protein-B by Dexamethasone and Caffeine in Lung Epithelial Cells. Neonatology 105: 357-363.

Fehrholz M, Speer CP, Kunzmann S. (2014) Caffeine and Rolipram affect smad signalling and TGF-β1 stimulated CTGF and transgelin expression in lung epithelial cells. PLoS One 9(5):e97357.

Glaser K, Wohlleben M, Speer CP. (2014) An 8-month history of meningitis in an extremely low birth weight infant? Long-lasting infection with Ureaplasma parvum. Z Geburtsh Neonatol 218:1-5.

Glaser K, Girschick H, Schropp C, Speer CP. (2014) Psychomotor development following early treatment of severe infantile vitamin B12 deficiency and West syndrome - is everything fine? A case report and review of literature. Brain Dev, pii:S0387-7604(14)00133-8.

Linz C, Collmann H, Meyer-Marcotty P, Böhm H, Krauß J, Müller-Richter UD, Ernestus RI, Wirbelauer J, Kübler AC, Schweitzer T. (2014) Occipital plagiocephaly: unilateral lambdoid synostosis versus positional plagiocephaly. Arch Dis Child Oct 1. pii: archdischild-2014-305944. doi: 10.1136/archdischild-2014-305944.

Mitra S, Aune D, Speer CP, Saugstad OD. (2014) Chorioamnionitis as a risk factor for retinopathy of prematurity: A systematic review and meta-analysis. Neonatology 105:189-199.

Nassen CA, Schaefer C, Wirbelauer J, Hönig A, Kranke P. (2014) Anesthesia and analgesia in the lactation period: Criteria for drug selection. Anaesthesist 63(5):415-421.

Petrova E, Neuner C, Haaf T, Schmid M, Wirbelauer J, Jurkutat A, Wermke K, Nanda I, Kunstmann E. (2014) A Boy with an LCR3/4-Flanked 10q22.3q23.2 Microdeletion and Uncommon Phenotypic Features. Mol Syndromol 5(1):19-24.

Speer CP, Halliday HL. (2014) Tore Curstedt – the basic science creator of porcine surfactant. Neonatology 106(3):242-244.

Stüber T, Frieauff E,Diessner J, Hönig A, Rehn M. (2014) Malignant extrarenal rhabdoid tumor: a case report. Case Rep. Perinat. Med aop; DOI 10.1515/crpm-2014-0023.

Sweet D, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Halliday HL; European Association of Perinatal Medicine. (2014) European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants--2013 update. Zhonghua Er Ke Za Zhi. 52(10):749-55.

Thomas W, Speer CP. (2014) Chorioamnionitis is essential in the evolution of bronchopulmonary dysplasia – The case in favour. Paediatr Respir Rev 15(1):49-52.

Vento M, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP. (2014) More about surfactant, oxygen, caffeine and chronic lung disease. Neonatology 105(4):320-322.

2013

Bersani I, Kunzmann S, Speer CP. (2013) Immunomodulatory properties of surfactant preparations. Expert Rev Anti Infect Ther 11:99-110.

Collins JJ, Kunzmann S, Kuypers E, Kemp MW, Speer CP, Newnham JP, Kallapur SG, Jobe AH, Kramer BW. (2013) Antenatal glucocorticoids counteract LPS changes in TGFβ-pathway and Caveolin-1 in ovine fetal lung. Am J Physiol Lung Cell Mol Physiol 304:L438-444.

Fehrholz M, Kunzmann S, Kramer BW, Speer CP. (2013) Amplification of Glucocorticoid-Mediated Surfactant Protein-B Expression by Physiologic Levels of Caffeine in vitro and invivo. Neonatology 103:346-352.

Fink S, Kunzmann S, Andres O, Eyrich M, Wiegering V. (2013) Haemophilia in extreme immature preterm infants: increased risk for intracranial haemorrhage? J Matern Fetal Neonatal Med 27(6):521-624.

Glaser K, Speer CP. (2013) Toll-like receptor signaling in neonatal sepsis and inflammation: a matter of orchestration and preconditioning. Expert Rev. Clin. Immunol 9:1239-1252.

Hallman M, Curstedt T, Halliday HL, Saugstad OD, Speer CP. (2013) Better neonatal outcomes: oxygen, surfactant and drug delivery. Neonatology 103:316-319.

Heinrich T, Nanda I, Rehn M, Zollner U, Frieauff E, Wirbelauer J, Grimm T, Schmid M. (2013) Live-Born Trisomy 22: Patient Report and Review. Mol Syndromol 3:262–269.

Hofmann C, Liese J, Schwarz T, Kunzmann S, Wirbelauer J, Nowak J, Hamann J, Girschick H, Graser S, Dietz K, Zeck S, Jakob F, Mentrup B. (2013) Compound heterozygosity of two functional null mutations in the ALPL gene associated with deleterious neurological outcome in an infant with hypophosphatasia. Bone 55:150-157.

Klotz D, Frölich K, Zollner U, Rehn M, Wirbelauer J. (2013) Unexpected respiratory distress in the delivery room - a rare differential diagnosis for the obstetrician and neonatologist. Z Geburtshilfe Neonatol 217:144-146.

Klotz D, Kneitz H, Wirbelauer J. (2013) Primary cutaneous aspergillosis in an extremely low birth weight preterm infant. Hautarzt 64:664-665.

Kranke P, Girard T, Lavand Homme P, Melber A, Jokinen J, Muellenbach RM, Wirbelauer J, Hönig A. (2013) Must we press on until a young mother dies? Remifentanil patient controlled analgesia in labour may not be suited as a "poor man's epidural". BMC Pregnancy Childbirth 2;13:139.

Kunzmann S, Collins JJP, Kuypers EV, Kramer BW. (2013) Thrown off balance: The effect of chorioamnionitis on the developing lung and immune system. Am J Obstet Gynecol 208:429-437.

Kunzmann S, Fehrholz M, Speer CP. (2013) Caffeine and Rolipram Down-Regulate SMAD Signalling and TGF-β-Stimulated CTGF and Transgelin Expression in Lung Epithelial Cells. Neonatology 103: 346-352.

Schröder D, Schweitzer T, Günthner-Lengsfeld T, Wirbelauer J. (2013) First afebrile seizure of an infant. Monatsschrift Kinderheilkunde 161: 496-498.

Speer CP, Sweet DG, Halliday HL. (2013) Surfactant therapy: past, present and future.
Early Hum Dev 89 Suppl 1:S22-S24.

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Vento M, Halliday HL. (2013) European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants – 2013 update. Neonatology 103:353-368.

Sweet DG, Halliday HL, Speer CP. (2013) Surfactant therapy for neonatal respiratory distress syndrome in 2013. J Matern Fetal Neonatal Med 26 Suppl 2:27-29.

Schröder D, Schweitzer T, Günthner-Lengsfeld T, Wirbelauer J. (2013) First afebrile seizure of an infant. Monatsschrift Kinderheilkunde 161:496-498.

Thomas W, Speer CP. (2013) Chorioamnionitis is essential in the evolution of bronchopulmonary dysplasia – The case in favour. Paediatr Respir Rev. pii: S1526-0542(13):00115-2.

Wasem S, Rifai M, Hoenig A, Wirbelauer J, Roewer N, Kranke P. (2013) Should opioids be routinely used for the inducation of general anaesthesia for caesarean section?
Anästhesiol Intensivmed Notfallmed Schmerzther 48: 374-377.

2012

Artmann T, Honig A, Wirbelauer J, Schaefer C, Schelling P, Kranke P. (2012) Breastfeeding after Anesthesia: Is a Cessacion of Breastfeeding obligatory? Geburtsh Frauenheilk. 72:983-986.

Bersani I, Fehrholz M, Kunzmann S, Speer CP. (2012) Synergistic Effect of Caffeine and Glucocorticoids on Surfactant Protein B Expression. Neonatology. 101:360-360.

Bersani I, Speer CP (2012): Nosocomial Sepsis in Neonatal Intensive Care: Inevitable or Preventable? Zeitschr Geburtsh Neonatol 216:186-190.

Bersani I, Speer CP, Kunzmann S. (2012) Surfactant protein A and D in pulmonary diseases of preterm infants. Expert Rev Anti Infect Ther 10:573-584.

Bersani I, Thomas W, Speer CP. (2012) Chorioamnionitis – the good or the evil for neonatal outcome? J Matern Fetal Neonatal Med 25S1:12-16.

Carrapato M, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP. (2012) Surfactant replacement: the search for a softer touch. Proceedings of the 27th International Workshop on Surfactant Replacement, Lisbon, June 2012.
Neonatology 101:311.

Eltermann T, Wößner R, Liese J, Wieg C, Wirbelauer J, Thomas W. (2012) Fatal pertussis in a preterm with hyperleukocytosis and necrotizing enterocolitis: considerations on pathogenesis and prevention. Klin Padiatr 224:461-462.

Fehrholz M, Bersani I, Kramer BW, Speer CP, Kunzmann S. (2012) Synergistic effect of caffeine and glucocorticoids on expression of surfactant protein B (SP-B) mRNA. PLoS ONE 7(12):e51575.

Fehrholz M, Kendl S, Prifert C, Weissbrich B, Lemon K, Rennick L, Duprex PW, Rima BK, Koning FA, Holmes RK, Malim MH, Schneider-Schaulies J. (2012) The innate antiviral factor APOBEC3G targets replication of measles, mumps and respiratory syncytial viruses. J Gen Virol. 93(Pt 3):565-76.

Halliday HL, Speer C. (2012) Cochrane review update. Neonatology 102:126.doi:10.1159/000339013.

Kunzmann S, Collins JJP, Kuypers E, Kramer BW. (2012) Effects of antenatal inflammation on the developing lung. Z Geburtshilfe Neonatol 216:177-85.

Kunzmann S, Fehrholz M, Bersani I, Speer CP. (2012) Molecular Characterization of the Synergistic Effect of Caffeine and Steroids on Surfactant Protein B Expression. Neonatology. 101:361-361.

Kuypers E, Ophelders D, Jellema RK, Kunzmann S, Gavilanes AW, Kramer BW. (2012) White matter injury following fetal inflammatory response syndrome induced by chorioamnionitis and fetal sepsis: Lessons from experimental ovine models. Early Hum Dev 88:931-6.

Lambermont VA, Been JV, Kunzmann S, Vanterpool SF, Newnham JP, Kallapur SG, Jobe AH, Kramer BW. (2012) Sex differences in lung gas volumes after lipopolysaccharide-induced chorioamnionitis in Fetal Sheep. Gend Med 9:278-86.

Laug R, Fehrholz M, Schütze N, Kramer BW, Krump-Konvalinkova V, Speer CP, Kunzmann S. (2012) IFN-γ and TNF-a Synergize to Inhibit CTGF Expression in Human Lung Endothelial Cells. PLoS One 2012;7:e45430.doi:10.1371.

Neuhaus W, Samwer F, Kunzmann S, Muellenbach RM, Wirth M, Speer CP, Roewer N, Förster CY. (2012) Lung endothelial cells strengthen, but brain endothelial cells weaken barrier properties of a human alveolar epithelium cell culture model. Differentiation 84:294-304.

Saling E, Speer CP, Schmidt S. (2012) Award of the Maternity Prize of the European Association of Perinatal Medicine on June 13, 2012 in Paris. Introduction and Laudatio for the winner of the obstetrical prize. Z Geburtsh Neonatol 216:235-236.

Schick J, Solymosi L, Günthner-Lengsfeld T, Krauß J, Wirbelauer J. (2012) Erfolgreiche interventionelle Okklusion einer riesigen cerebralen AV-Malformation bei einem 6 Tage alten Neugeborenen mit dekompensierter Herzinsuffizienz. Monatsschrift Kinderheilkunde 160, S1.

Speer CP, Halliday HL, Schmidt S. Laudatio. Mikko Hallman. (2012) A major translator of basic science into neonatal medicine. Z Geburtsh Neonatol 216:237-238.

Speer CP, Sweet DG. (2012) Surfactant Replacement: Present and Future. In: The Newborn Lung. Bancalari E (ed). 2nd Ed.Elsevier Saunders Philadelphia 283-299.

Stein RG, Diessner J, Frieauff E, Zollner U, Rehn M, Dietl J, Hönig A. (2012) Acute foeto-foetal transfusion syndrome – case report and review of the literature. Z Geburtshilfe Neonatol. Jun;216(3):147-9.

Stoevesandt J, Borozdin W, Girschick G, Hamm H, Höcht B, Kohlhase J, Volz A, Wiewrodt B, Wirbelauer J. (2012) Lethal Junctional Epidermolysis Bullosa with Pyloric Atresia due to Compound Heterozygosity for Two Novel Mutations in the Integrin β4 Gene. Klin Padiatr. 224:8-11.

Thomas W, Speer CP. (2012) Intrauterine inflammation and its sequelae: does chorioamnionitis really matter for outcome of very low birth weight infants? Zeitschr Geburtsh Neonatol 216:173-6.

Willems CH, Kloosterboer N, Kunzmann S, Kramer BW, Zimmermann LJ, van Iwaarden JF. (2012) Dissociation of transforming growth factors β1 and β2 from surfactant protein A (SP-A) by deglycosylation or deoxycholate treatment. J Immunol Methods 375:111-117.

Willems CH, Urlichs F, Seidenspinner S, Kunzmann S, Speer CP, Kramer BW. (2012) Poractant alfa (Curosurf®) increases phagocytosis of apoptotic neutrophils by alveolar macrophages in vivo. Respir Res 13:17.

Wirbelauer J, Bauer J, Hebestreit H, Thomas W. (2012) Plastic Bronchitis 3 Years After Fontan Palliation. Klin Padiatr. 224:38.

2011

Beer M, Wirth C, Neubauer H, Wirbelauer J. (2011) Radiology in pediatric intensive care units. Med Klin (Munich). 106:103-10.

Beyrich C, Loeffler J, Kobsar A, Speer CP, Kneitz S, Eigenthaler M. (2011) Infection of human coronary artery endothelial cells by Group B Streptococcus (GBS) contributes to dysregulation of apoptosis, hemostasis and innate immune responses. Mediators Inflamm 971502.

Kobsar A, Siauw C, Gambaryan S, Hebling S, Speer CP, Schubert-Unkmeir A, Eigenthaler M. (2011) Neisseria meningitidis induces platelet inhibition and increases vascular endothelial permeability via nitric oxide regulated pathways. Thromb Haemost 106:1127-38.

Kochel J, Meyer-Marcotty P, Wirbelauer J, Böhm H, Kochel M, Thomas W, Bareis U, Hebestreit H, Speer CP, Stellzig-Eisenhauer A. (2011) Treatment Modalities Of Infants With Upper Airway Obstruction – Review Of The Literature and Presentation Of Novel Orthopedic Appliances. Cleft Palate Craniofac 48:44-55.

Kranke P, Frambach T, Schelling P, Wirbelauer J, Schaefer C, Stamer U. (2011) Anaesthesia and breastfeeding: Should breastfeeding be discouraged? Anasthesiol Intensivmed Notfallmed Schmerzther 46:304-311.

Kunzmann S, Collins JJ, Yang Y, Uhlig S, Kallapur S, Speer CP, Jobe AH, Kramer BW. (2011) Antenatal inflammation reduces cav-1 expression and influences multiple signalling pathways in preterm fetal lungs. Am J Respir Cell Mol Biol 45:969-76.

Neubauer H, Wirbelauer J, Lengenfelder B, Hahn D, Beer M. (2011) Kardiovaskuläre MRT bei pädiatrischen Patienten. Monatsschr Kinderheilkd 159:333-342.

Ozek E, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP. (2011) Surfactant broadens its horizons. Neonatology 99:313.

Ozek E, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP. (2011) Preface. Neonatology 99:314-315.

Radike K, Kunzmann S, Abele-Horn M, Beer M, Hebestreit H. (2011) Osteoarticular infection by Candida albicans in an infant with Cystic Fibrosis. J Med Microbiol. 60:1542-5.

Saugstad OD, Speer CP, Halliday HL. (2011) Oxygen saturation in immature babies: Revisited with updated recommendations. Neonatology 100:217-218.

Seehase M, Gantert M, Ladenburger A, Garnier Y, Kunzmann S, Thomas W, Wirbelauer J, Speer CP, Kramer BW. (2011) Myocardial Response in Preterm Fetal Sheep Exposed to Systemic Endotoxinaemia. Pediatr Res 70:242-6.

Speer CP. (2011) Neonatal Respiratory Distress Syndrome (RDS): An Inflammatory Disease? Neonatology 99:316-9.

Speer CP, Groneck P. (2011) Intensivmedizin bei Früh- und Neugeborenen.
In: Buchardi H, Larsen R, Schuster H-P,  Suter PM (Hrsg): Die Intensivmedizin, 11. Aufl.,
Springer Verlag Berlin, Heidelberg, New York, 1115-1158.

Speer CP, Groneck P. (2011) Intensivmedizin bei Früh- und Neugeborenen.
In: Buchardi H. Larsen R, Schuster H-P, Suter PM (Hrsg): Klinikmanual Intensivmedizin, 1. Aufl., Springer Verlag Berlin, Heidelberg, New York, 534-574.

Speer CP, Halliday HL. (2011) Mikko Hallman – a major translator of basic science into neonatal medicine. Neonatology 100:300-302.

Speer CP, Halliday HL, Schmidt S. (2011) Laudatio. Mikko Hallman – A major translator of basic science into neonatal medicine. Z Geburtsh Neonatol 216:237-238.

Thomas W, Seidenspinner S, Kramer BW, Wirbelauer J, Kawczyńska-Leda N, Szymankiewicz M, Speer CP. (2011) Airway angiopoietin-2 in ventilated very preterm infants: Association with prenatal factors and neonatal outcome. Pediatr Pulmonol 46:777-84.

Thomas W, Speer CP. (2011) Chorioamnionitis: Important risk factor or innocent bystander for neonatal outcome? Neonatology 99:177-187.

Tosson AMS, Speer CP. (2011) Microbial Pathogens Causative of Neonatal Sepsis in Arabic Countries. J Matern Fetal Neonatal Med. 24:990-4.

Unzicker A, Pingault V, Meyer T, Rauthe S, Schütz A, Kunzmann S. (2011) A novel SOX10 mutation in a patient with PCWH who developed hypoxic-ischemic encephalopathy after E.coli sepsis. Eur J Pediatr 170:1475-80.

Wiegering V, Winkler B, Wirbelauer J, Walter U, Meyer T, Bakchoul T, Wölfl M, Eyrich M, Schlegel PG. (2011) Allogeneic blood stem cell transplantation in Glanzmann thrombasthenia complicated by platelet alloimmunization / Fallbericht einer allogenen Stammzelltransplantation bei Thrombasthenia Glanzmann. Klin Padiatr 223:173-175.

Wirbelauer J. (2011) Physiologie und Pathologie des Früh- und Neugeborenen. Angeborene Herzfehler in: Rath W, Gembruch U, Schmidt St. Geburtshilfe und Perinatalmedizin, 2. Auflage Thieme-Verlag.

Wirbelauer J. (2011) Perinatale Infektionen. In: Abele-Horn M (Hrsg.): MIQ Genitalinfektionen 10 und 11, 2. Auflage, Elsevier-Verlag.

Wirbelauer J, Hebestreit H, Marx A, Mark EJ, Speer CP. (2011) Familial Pulmonary Capillary Hemangiomatosis Early in Life. Case Reports in Pulmonology, doi:10.1155/2011/827591.

Wirbelauer J, Seidenspinner S, Thomas W, Kunzmann S, Speer CP. (2011) Funisitis is associated with increased interleukin-10 gene expression in cord blood mononuclear cells in preterm infants ≤32 weeks of gestation. Eur J Obstet Gynecol Reprod Biol 155:31-5.

Wirbelauer J, Thomas W, Speer CP. (2011) Response of leukocytes and nucleated red blood cells in very low birth weight preterm infants after exposure to intrauterine inflammation. J Matern Fetal Neonatal Med 24:348-5.

2010

Baibarina E, Curstedt T, Halliday H, Hallman M, Saugstad OD, Speer CP. (2010) A quarter century of surfactant research – from early neonatal stabilization to long-term outcome.
Neonatology 97:355.

Baibarina E, Curstedt T, Halliday H, Hallman M, Saugstad OD, Speer CP. (2010) Global neonatal mortality and hypothermia for perinatal asphyxia. Preface. Neonatology 97:356-357.

Eltermann T, Menendez-Castro C, Wössner R, Thomas W. (2010) Early course of Berardinelli-Seip congenital lipodystrophy (BSCL). Klin Pädiatr 222:308-309.

Frambach T, Wirbelauer J, Schelling P, Rieger R, Muellenbach RM, Roewer N, Kranke P. (2010) Patient-controlled intravenous analgesia with remifentanil as an alternative to epidural analgesia during labor: case series and discussion of medicolegal aspects. Z Geburtsh Neonatol 214:145-150.

Halliday HL, Speer CP. (2010) Editorial Note. Neonatology 98:I-II.

Kunzmann S, Glogger K, Been JV, Kallapur SG, Nitsos I, Moss TJ, Speer CP, Newnham JP, Jobe AH, Kramer BW. (2010) Thymic changes after chorioamnionitis induced by intraamniotic lipopolysaccharide in fetal sheep. Am J Obstet Gynecol 202:476.e1-9.

Ladenburger A, Seehase M, Kramer BW, Thomas W, Wirbelauer J, Speer CP, Kunzmann S. (2010) Glucocorticoids potentiate IL-6 induced SP-B expression in H441 cells by enhancing the Jak/Stat signaling pathway. Am J Physiol Lung Cell Mol Physiol 299:L578-584.

Speer CP. (2010) Inflammatory Mechanisms in Bronchopulmonary Dysplasia. In: Abman SH (Ed.): Bronchopulmonary Dysplasia. Lung Biology in Health and Disease; Vol. 240. Informa Health Care New York, 133-145.

Speer CP. (2010) Physiologie und Pathologie des Neugeborenen. In: Rath W, Gembruch U, Schmidt S (Hrsg): Geburtshilfe und Perinatalmedizin, 2. Aufl., Thieme Verlag Stuttgart, 683-708.

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Halliday HL. (2010) European Consensus Guidelines on the management of neonatal respiratory distress syndrome in preterm infants – 2010 update. Neonatology 97:402-417.

Thomas W, Seidenspinner S, Kawczynska-Leda N, Chmielnicka-Kopaczyk M, Marx A, Wirbelauer J, Szymankiewicz M, Speer CP. (2010) Clara Cell secretory protein in tracheobronchial aspirates and umbilical cord serum of extremely premature infants with systemic inflammation. Neonatology 97:228-234.

Thomas W, Seidenspinner S, Kawczynska-Leda N, Wirbelauer J, Szymankiewicz M, Speer CP. (2010) Soluble receptor for advanced glycation end products (sRAGE) in tracheobronchial aspirate fluid and cord blood of very low birth weight infants with chorioamnionitis and funisitis. Early Hum Dev 86:593-598.

Thomas W, Speer CP. (2010) Chorioamnionitis: Important risk factor or innocent bystander for neonatal outcome? Neonatology 99:177-187.

Wirbelauer J. (2010) Neonatologische Intensivmedizin - welche Bedeutung hat die Messung des zentralen Venendruckes bei der Beurteilung eines Volumendefizites? Päd Praxis. 75:166-169.

Wirbelauer J: Physiologie und Pathologie des Früh- und Neugeborenen. Angeborene Herzfehler. In: Rath W, Gembruch U, Schmidt S (Hrsg). (2010) Geburtshilfe und Perinatalmedizin, 2. AAufl., Thieme-Verlag.

Wirbelauer J: Perinatale Infektionen. In: Abele-Horn M (Hrsg). (2010) MIQ Genitalinfektionen 10 und 11, 2. Aufl., Elsevier-Verlag.

Wirbelauer J, Speer CP. (2010) Significance of nitric oxide inhalation (NO) in preterm infants < 34 weeks of gestation. Klin Padiatr 222:56-61.

Wirbelauer J, Thomas W, Rieger L, Speer CP. (2010) Intrauterine growth retardation in preterm infants ≤32 weeks of gestation is associated with low white blood cell counts.
Am J Perinatol 27:819-824.

Wirbelauer J, Thomas W, Speer CP. (2010) Früh- und Neugeborene mit einem Acute Respiratory Distress Syndrome (ARDS): welche Rolle spielt die Surfactantsubstitution?
Z Geburtsh Neonatol 213:33-41.

Wirbelauer J, Thomas W, Speer CP. (2010) Response of leukocytes and nucleated red blood cells in very low birth weight preterm infants after exposure to intrauterine inflammation. J Matern Fetal Neonatal Med Epub ahead of print.

Kontakt, Öffnungszeiten, Sprechzeiten

Öffnungszeiten:

nach telefonischer Terminvereinbarung
+49 931 201-27855

 

 

Telefon:

Kinderklinik-Pforte
+49 931 201-27728 oder
+49 931 201-27915

Notfälle
+49 931 201-27728

Intensivstation
+49 931 201-27726

Direktions-Sekretariat
+49 931 201-27831 oder
+49 931 201-27832

Fax:
+49 931 201-27798


Anschrift:

Kinderklinik und Poliklinik des Universitätsklinikums und der Bayerischen Julius-Maximilians-Universität | Josef-Schneider-Straße 2 | Haus D31 | 97080 Würzburg | Deutschland