Publikationen Pädiatrische Rheumatologie, Infektiologie, Immunologie

2017

Carbonell-Estrany X, Fullarton JR, Gooch KL, Gouyon J-B, Lanari M, Rodgers-Gray BS, Thwaites RJ, Vo PG, Liese JG. (2017) The influence of birth weight amongst 33-35 weeks gestational age (wGA) infants on the risk of respiratory syncytial virus (RSV) hospitalisation: a pooled analysis. J Matern Fetal Neonatal Med 30(2):134-140.

Hagemann C, Seeger K, Krämer A, Liese JG, Streng A. (2017) Entwicklung der Varizellen-Impfraten und mögliche Einflussfaktoren auf die Impfentscheidung der Eltern im Münchner Raum in den Jahren 2009-201 nach Einführung der allgemeinen Varizellenimpfung. Gesundheitswesen 79(4):286-295.

Hagemann C, Streng A, Kraemer A, Liese JG. (2017) Heterogeneity in coverage for measles and varicella vaccination in toddlers – analysis of factors influencing parental acceptance. BMC Public Health 17:724.

Hofmann SR, Böttger F, Range U, Lück C, Morbach H, Girschick HJ, Suttorp M, Hedrich CM. (2017) Serum Interleukin-6 and CCL11/Eotaxin May Be Suitable Biomarkers for the Diagnosis of Chronic Nonbacterial Osteomyelitis. Front Pediatr 5:256.

Hofmann SR, Kapplusch F, Girschick HJ, Morbach H, Pablik J, Ferguson PJ, Hedrich CM. (2017) Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment. Curr Osteoporos Rep 15(6):542-554.

Mentrup B, Girschick H, Jakob F, Hofmann C. (2017) A homozygous intronic branch-point deletion in the ALPL gene causes infantile hypophosphatasia. Bone 94:75-83.

Prelog M. (2017) Tonsillitis – wann und wie behandeln. Der Allgemeinarzt 14:1-7.

Seefried L, Baumann J, Hemsley S, Hofmann C, Kunstmann E, Kiese B, Huang Y, Chivers S, Valentin MA, Borah B, Roubenoff R, Junker U, Jakob F. (2017) Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia. J Clin Invest 127(6):2148-2158.

Segerer F, Seeger K, Maier A, Hagemann C, Schoen C, van der Linden M, Streng A, Rose MA, Liese JG. (2017) Therapy of 645 children with parapneumonic effusion and empyema – a  German nationwide surveillance study. Pediatr Pulmonol 52:540-547.

Silwedel C, Frieauff E, Thomas W, Liese JG, Speer CP. (2017) Secondary haemophagocytic lymphohistiocytosis triggered by postnatally acquired cytomegalovirus infection in a late preterm infant. Infection 45(3):355-359.

Streng A, Grote V, Rack-Hoch A, Liese JG. (2017) Decline of neurological varicella complications in children during the first seven years after the introduction of universal varicella vaccination in Germany, 2005-2011. Pediatr Infect Dis J 36(1):79-86.

Streng A, Liese JG. (2017) Nach der Pandemie ist vor der Pandemie? Krankheitslast durch Influenza A(H1N1)pdm09 bei Kindern in Deutschland nach dem Jahr 2009. Kinder- und Jugendmedizin 17:247-255.

Ugor E, Simon D, Almanzar G, Pap R, Najbauer J, Németh P, Balogh P, Prelog M, Czirják L, Berki T. (2017) Increased proportions of functionally impaired regulatory T cell subsets in systemic sclerosis. Clin Immunol 184:54-62.

2016

Almanzar G, Klein M, Schmalzing M, Hilligardt D, El Hajj N, Kneitz H, Wild V, Rosenwald A, Benoit S, Hamm H, Tony HP, Haaf T, Goebeler M, Prelog M. (2016) Disease Manifestation and Inflammatory Activity as Modulators of Th17/Treg Balance and RORC/FoxP3 Methylation in Systemic Sclerosis. Int Arch Allergy Immunol 171:141-154.

Almanzar G, Mayerl C, Seitz JC, Höfner K, Brunner A, Wild V, Jahn D, Geier A, Fassnacht M, Prelog M. (2016) Expression of 11beta-hydroxysteroid-dehydrogenase type 2 in human thymus. Steroids 110:35-40.

Almanzar G, Schmalzing M, Trippen R, Höfner K, Weißbrich B, Geissinger E, Meyer T, Liese J, Tony HP, Prelog M. (2016) Significant IFNγ responses of CD8+ T cells in CMV-seropositive individuals with autoimmune arthritis J Clin Virol 77:77-84.

Daschkey S, Bienemann K, Schuster V, Kreth HW, Linka RM, Hönscheid A, Fritz G, Johannes C, Fleckenstein B, Kempkes B, Gombert M, Ginzel S, Borkhardt A. (2016) Fatal Lymphoproliferative Disease in Two Siblings Lacking Functional FAAP24. J Clin Immunol 2016;36(7):684-92.

Hofmann C, Seefried L, Jakob F. (2016) Asfotase alfa: enzyme replacement therapy for the treatment of bone disease in hypophosphatasia. Drugs of Today 52(5):1-16.

Hofmann SR, Kubasch AS, Range U, Laass MW, Morbach H, Girschick HJ, Hedrich CM. (2016) Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO). Rheumatol Int 36(6):769-779.

Hofmann SR, Schnabel A, Rösen-Wolff A, Morbach H, Girschick HJ, Hedrich CM. (2016) Chronic Nonbacterial Osteomyelitis: Pathophysiological Concepts and Current Treatment Strategies. J Rheumatol 43(11):1956-1964.

Klein M, Schmalzing M, Almanzar G, Benoit S, Hamm H, Tony HP, Goebeler M, Prelog M. (2016) Contribution of CD8+ T cells to inflammatory cytokine production in systemic sclerosis (SSc). Autoimmunity 49:532-546.

Mentrup B, Girschick H, Jakob F, Hofmann C. (2016) A homozygous intronic branch-point deletion in the ALPL gene causes infantile hypophosphatasia. Bone 94:75-83.

Noster R, de Koning HD, Maier E, Prelog M, Lainka E, Zielinski CE. (2016) Dysregulation of  proinflammatory versus anti-inflammatory human TH17 cell functionalities in the autoinflammatory Schnitzler syndrome. J Allergy Clin Immunol 138:1161-1169.

Prelog M, Hilligardt D, Schmidt CA, Przybylski GK, Leierer J, Almanzar G, El Hajj N, Lesch KP, Arolt V, Zwanzger P, Haaf T, Domschke K. (2016) Hypermethylation of FOXP3 Promoter and Premature Aging of the Immune System in Female Patients with Panic Disorder? PLoS One 11:e0157930.

Prelog M, Gorth P, Zwazl I, Kleines M, Streng A, Zlamy M, Heinz-Erian P, Wiedermann U. (2016) Universal Mass Vaccination Against Rotavirus: Indirect Effects on Rotavirus Infections in Neonates and Unvaccinated Young Infants Not Eligible for Vaccination. J Infect Dis 214:546-555.

Streng A, Wiegering V, Liese JG. (2016) Varicella in paediatric oncology patients in the post-vaccine era – analysis of routine hospital data from Bavaria (Germany), 2005-2011. Pediatr Hematol Oncol. 33(7-8):468-479.

Whyte MP, Rockman-Greenberg C, Ozono K, Riese R, Moseley S, Melian A, Thompson DD, Bishop N, Hofmann C. (2016) Asfotase alfa treatment improves survival for perinatal and infantile hypophosphatasia. J Clin Endocrinol Metab 101(1):334–342.

Zlamy M, Almanzar G, Parson W, Schmidt C, Leierer J, Weinberger B, Jeller V, Unsinn K, Eyrich M, Würzner R, Prelog M. (2016) Efforts of the human immune system to maintain the peripheral CD8+ T cell compartment after childhood thymectomy. Immun Ageing 13:3.

2015

Almanzar G, Schönlaub J, Hammerer-Lercher A, Koppelstaetter C, Bernhard D, Prelog M. (2015) Influence of the delivery modus on subpopulations and replication of lymphocytes in mothers and newborns. Early Hum Dev 91(12):663-670.

Eberhardt CS, Haas JP, Girschick H, Schwarz T, Morbach H, Rösen-Wolff A, Foell D, Dannecker G, Schepp C, Ganser G, Honke N, Eggermann T, Müller-Berghaus J, Wagner N, Ohl K, Tenbrock K. (2015) No association of IL-12p49 pro1.1 polymorphism with juvenile idiopathic arthritis. Pediatr Rheumatol Online J 13(1):61.

Girschick H, Wolf C, Morbach H, Hertzberg C, Lee-Kirsch MA. (2015) Severe immune dysregulation with neurological impairment and minor bone changes in a child with spondyloenchondro-dysplasia due to wo novel mutations in the ACP5 gene. Pediatr Rheumatol Online 13(1):37.

Graser S, Mentrup B, Schneider D, Klein-Hitpass L, Jakob F, Hofmann C. (2015) Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line. Bone 79:150-61.

Herbst M, Gazendam R, Reimnitz D, Sawalle-Belohradsky J, Groll A, Schlegel PG Belohradsky B, Renner E, Klepper J, Grimbacher B, Kuijpers T, Liese J. (2015) Chronic Candida albicans meningitis in a 4-year-old girl with a homozygous mutation in the CARD9 gene (Q295X). Pediatr Infect Dis J 34(9):999-1002.

Hofmann C, Jakob F, Seefried L, Mentrup B, Graser S, Plotkin H, Girschick HJ, Liese J. (2015) Recombinant enzyme replacement therapy in hypophosphatasia. Subcell Biochem 76:323-341.

Hofmann SR, Kubasch AS, Ioannidis C, Rösen-Wolff A, Girschick HJ, Morbach H, Hedrich CM. (2015) Altered expression of IL-10 family cytokines in monocytes from CRMO patients results in enhanced IL-1b expression and release. Clin Immunol 161(2):300-307.

Holl K, Rosenlund M, Giaquinto C, Sifverdal SA, Carmona A, Larcombe J, Garcia-Sicilia J, Fuat A, Muñoz ME, Arroba ML, Sloesen B, Vollmar J, Pirçon JY, Liese JG. (2015) The impact of childhood acute otitis media on parental quality of life in a prospective observational cohort study. Clin Drug Investig 35(10):613-624.

León-Calvijo MA, Leal-Castro AL, Almanzar-Reina GA, Rosas-Pérez JE, García-Castañeda JE, Rivera-Monroy ZJ. (2015) Antibacterial activity of synthetic peptides derived from lactoferricin against Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212. Biomed Res Int 453826.

Liese J, Prelog M. (2015) Impfen und Allergien. Impfkompendium. Hrsg. Spiess, Heininger, Jilg, Georg Thieme Verlag KG 45:306-314.

Liese J, Streng A: Varizellen. In: Spiess, Heininger Jilg (Hrsg) (2015) Impfkompendium, 8. Auflage. Georg-Thieme-Verlag Stuttgart, New York, 298-303.

Ombrello MJ, Remmers EF, Tachmazidou I, et al, Schwarz T. (2015) International Childhood Arthritis Genetics (INCHARGE) Consortium; British Society of Pediatric and Adolescent Rheumatology BSPAR Study Group: HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis. Proc Natl Acad Sci U S A 112(52):15970-15975.

Prelog M. (2015) Immunologie der Entzündung. Kinder- und Jugendmedizin, Schattauer GmbH, Verlag für Medizin und Naturwissenschaften 5:303-312.

Rieber N, Singh A, Öz H, Carevic M, Bouzani M, Amich J, Ost M, Ye Z, Ballbach M, Schäfer I, Mezger M, Klimosch SN, Weber AN, Handgretinger R, Krappmann S, Liese J, Engeholm M, Schüle R, Salih HR,Marodi L, Speckmann C, Grimbacher B, Ruland J, Brown GD, Beilhack A, Loeffler J, Hartl D. (2015) Pathogenic fungi regulate immunity by inducing neutrophilic myeloid-derived suppressor cells. Cell Host Microbe 17(4):507-514.

Streng A, Prifert C, Weissbrich B, Liese JG; Bavarian PICU Study Group on Influenza and Other Viral ARI. (2015) Continued high incidence of children with severe influenza A(H1N1)pdm09 admitted to paediatric intensive care units in Germany during the first three post-pandemic influenza seasons, 2010/11-2012/13. BMC Infect Dis 15:573.

Whyte MP, Rockman-Greenberg C, Ozono K, Riese R, Moseley S, Melian A, Thompson DD, Bishop N, Hofmann C. (2015) Asfotase Alfa Treatment Improves Survival for Perinatal and Infantile Hypophosphatasia. J Clin Endocrinol Metab Epub.

2014

Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B. (2014) Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect. Nature Commun 5:4746.

Gazendam RP, van Hamme JL, Tool AT, van Houdt M, Verkuijlen PJ, Herbst M, Liese JG, van de Verdoonk FL, Roos D, van den Berg TK, Kuijpers TW. (2014) Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects. Blood 124:590-59.

Hofmann C, Wurm M, Schwarz T, Neubauer H, Beer M, Girschick H, Morbach H. (2014) A standardized clinical and radiological follow-up of patients with chronic non bacterial Osteomyelitis treated with pamidronate. Clin Exp Rheumatol Jul-Aug;32(4):604.

Krumbholz A, Neubert A, Joel S, Girschick H, Huppertz HI, Kaiser P, Liese J, Streng A, Niehues T, Peters J, Sauerbrey A, Schroten H, Tenebaum T, Wirth S, Zell R, Sauerbrei A. (2014) Prevalence of hepatitis E virus antibodies in children in Germany. Pediatr Infect Dis J 33:258-26.

Liese JG, Silfverdal SA, Giaquinto C, Carmona A, Larcombe JH, Garcia-Sicilia J, Fuat A, Garces-Sanchez M, Arroba Basanta ML, Hiraldo EM, Cantarutti L, Kroeniger W, Vollmar J, Holl K, Pirçon JY, Roselund MR. (2014) Incidence and clinical presentation of acute otitis media in children aged <6 years in European medical practices. Epidemiol Infect 142:1778-1788 doi:10.1017/S095026881300274.

Liese J, Streng A: Acht Jahre generelle Varizellenimpfung – Akzeptanz, Erfolge, Probleme und Ausblick. In: Bayerisches Staatsministerium für Gesundheit und Pflege (Hrsg. (2014) Impfen – eine gesamtgesellschaftliche Verantwortung. Berichtsband zur 3. Nationalen Impfkonferenz 2013. Asterion Germany GmbH, Viernheim, 26-28; www.nationale-impfkonferenz.de

Rose MA, Damm O, Greiner W, Knuf M, Wutzler P, Liese JG, Krüger H, Wahn U, Schaberg T, Schwehm M, Kochmann TF, Eichner M. (2014) The epidemiological impact of childhood influenza vaccination using live-attenuated influenza vaccine (LAIV) in Germany: predictions of a simulation study. BMC Infect Dis 14:40; doi: 10.1186/1471-2334-14-40.

Sauerbrei A, Langenhan T, Brandstädt A, Schmidt-Ott R, Krumbholz A, von Kries R, Girschick H, Huppertz H-I, Kaiser P, Liese J, Streng A, Niehus T, Peters J, Sauerbrey A, Schroten H, Tenenbaum T, Wirth S, Wutzler P. (2014) Prevalence of antibodies against influenza A and B viruses in children in Germany, 2008 to 2010. Euro Surveill. 19(5):pii=2068.

Streng A, Liese JG. (2014) Decline of varicella vaccination in German surveillance regions after recommendation of separate first-dose vaccination for varicella and measles-mumps-rubella. Vaccine 32:897-900.

Streng A, Liese JG. (2014) Fifteen years of routine childhood varicella vaccination in the United States – strong decrease in the burden of varicella disease and no negative effects on the population level thus far Editorial. Translational Pediatrics 2014;3(4):268-272;doi: 10.3978/j.issn.2224-4336.2014.10.02.

Mornet E, Hofmann C, Bloch-Zupan A, Girschick H, Le Merrer M. (2014) Clinical utility gene card for: Hypophosphatasia – update 2013. Eur J Hum Genet. Apr;22(4).

Morbach H, Girschick HJ: Nichtbakterielle Osteomyelitis. In: Wagner N, Dannecker G (Hrsg). (2014) Pädiatriche Rheumatologie. Springer-Verlag Berlin, Heidelberg, New York, 524-529.

2013

Almanzar G, Ottensmeier B, Liese J, Prelog M. (2013) Assessment of IgG avidity against pertussis toxin and filamentous hemagglutininin via an adapted enzyme-linked immunosorbent assay (ELISA) using ammonium thiocyanate. J Immunol Methods 387:36-42.

Almanzar G, Zlamy M, Koppelstaetter C, Brunner A, Jeller V, Duftner C, Dejaco C, Brunner J, Prelog M. (2013) Increased replication of CD4+ naive T cells and changes in T cell homeostasis in a case of acute exacerbation of juvenile idiopathic arthritis: a case comparison study. J Med Case Rep 21;7:135.

Almanzar G, Eberle G, Lassacher A, Specht C, Koppelstaetter C, Heinz-Erian P, Trawöger R, Bernhard D, Prelog M. (2013) Maternal cigarette smoking and its effect on neonatal lymphocyte subpopulations and replication. BMC Pediatr 18;13:57.

Andres O, Strehl K, Kölsch U, Kunzmann S, Lebrun AH, Stroh T, Schwarz K, Morbach H, von Bernuth H, Liese J. (2013) Even in pneumococcal sepsis CD62L shedding on granulocytes proves to be a reliable functional test for the diagnosis of interleukin-1 receptor-associated kinase-4 deficiency. Pediatr Infect Dis J 32:1017-9.

Bringmann G, Thomale K, Bischof S, Schneider C, Schultheis M, Schwarz T, Moll H, Schurigt U. (2013) A novel Leishmania major amastigote assay in 96-well format for rapid drug screening and its use for discovery and evaluation of a new class of leishmanicidal quinolinium salts. Antimicrob Agents Chemother 57:3003-11.

Carbonell-Estrany X, Fullarton JR, Gooch KL, Vo PG, Figueras-Aloy J, Lanari M, Gouyon JB, Liese JG. (2013) Effects of parental and household smoking on the risk of respiratory syncytial virus (RSV) hospitalisation in late-preterm infants and the potential impact of RSV prophylaxis. J Matern Fetal Neonatal Med 26:926-31.

Hedrich CM, Hofmann SR, Pablik J, Morbach H, Girschick HJ. (2013) Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO).
Pediatr Rheumatol Online J.23;11:47.

Hedrich CM, Hahn G, Girschick HJ, Morbach H. (2013) A clinical and pathomechanistic profile of chronic nonbacterial osteomyelitis/chronic recurrent multifocal osteomyelitis and challenges facing the field. Expert Rev Clin Immunol 9:845-54.

Hofmann C, Girschick HJ, Mentrup B, Graser S, Seefried L, Liese J, Jakob F. (2013) Clinical aspects of hypophosphatasia:an update. Clin Rev Bone Miner Metab 11:60-70.

Hofmann C, Liese J, Schwarz T, Kunzmann S, Wirbelauer J, Nowak J, Hamann J, Girschick H, Graser S, Dietz K, Zeck S, Jakob F, Mentrup B. (2013) Compound heterozygosity of two functional null mutations in the ALPL gene associated with deleterious neurological outcome in an infant with hypophosphatasia. Bone 55:150-7.

Krumbholz A, Neubert A, Girschick H, Huppertz HI, Kaiser P, Liese J, Streng A, Niehus T, Peters J, Sauerbrey A, Schroten H, Tenenbaum T, Wirth S, Sauerbrei A. (2013) Prevalence of antibodies against hepatitis A virus among children and adolescents in Germany. Med Microbiol Immunol 202:417-24.

Liese J, Abele-Horn M, Beer M, Forster J, Heininger U, Nadal D, Rose M, Scholz H. (2013) Diagnose und Behandlung der Pneumonie im Kindesalter. Monatsschrift Kinderheilkunde 8:703-712.

Liese JG, Cohen C, Rack A, Pirzer K, Eber S, Blum M, Greenberg M, Streng A. (2013) The effectiveness of varicella vaccination in children in Germany. A case-control study. Pediatr Infect Dis J 32:998-1004.

Morbach H, Girschick HJ. (2013) B-cell targeted therapy for children and adolescents with rheumatic diseases. Z Rheumatol 72:347-53.

Morbach H, Hedrich CM, Beer M, Girschick HJ. (2013) Autoinflammatory bone disorders.
Clin Immunol 147:185-96.

Prelog M, Almanzar G, Rieber N, Ottensmeier B, Zlamy M, Liese J. (2013) Differences in IgG antibody avidity after an acellular pertussis (aP) booster in adolescents after a whole cell (wcP) or a aP primary vaccination. Vaccine 31:387-93.

Prelog M, Egli A, Zlamy M, Hirsch HH. (2013) JC and BK polyomavirus-specific Immunoglobulin G responses in patients thymectomized in early childhood. J Clin Virol 58:553-558.

Prelog M. (2013) Differential approaches for vaccination from childhood to old age. Gerontology 59:230-9.

Prelog M, Schönlaub J, Würzner R, Koppelstaetter C, Almanzar G, Brunner A, Gasser M, Prommegger R, Häusler G, Kapelari K, Högler W. (2013) Lower CD28+ T cell proportions were associated with CMV-seropositivity in patients with Hashimoto's thyroiditis. BMC Endocr Disord 5;13:34.

Prelog M, Schönlaub J, Jeller V, Almanzar G, Höfner K, Gruber S, Eiwegger T, Würzner R. (2013) Reduced varicella-zoster-virus (VZV)-specific lymphocytes and IgG antibody avidity in solid organ transplant recipients. Vaccine 31:2420-6.

Prifert C, Streng A, Krempl CD, Liese J, Weissbrich B. (2013) Novel Respiratory Syncytial Virus A genotype, Germany, 2011-2012. Emerg Infect Dis 19:1029-30.

Schwarz T, Remer KA, Nahrendorf W, Masic A, Siewe L, Müller W, Roers A, Moll H. (2013) T cell-derived IL-10 determines leishmaniasis disease outcome and is suppresses by a dendritic cell based vaccine. PLoS Pathog 9:e1003476.

Segerer F, Morbach H, Hassold N, Kleinert S, Tony HP, Roesler J, Liese J. (2013) A 58-year-old man with respiratory insufficiency after a 50-year history of hypersensitivity pneumonitis and pulmonary Aspergillus infections. J Allergy Clin Immunol Pract 1:677-80.

Simon A, Muller A, Kaiser P, Topfner N, Berner R, Laws HJ, Knorr M, Hufnagel M, Beyersdorff A, Heister P, Becker C, Liese J, Tenenbaum T. (2013) The Paed IC project-Antibiotic Stewardship and Hospital Hygiene to Prevent Infection with Resistant Pathogens. Klin Padiatr 225:93-95.

Straßburg HM. (2013) Vaccination ethics and health care. Klin Padiatr 225:1-2.

Streng A, Grote V, Carr D, Hagemann C, Liese JG. (2013) Varicella routine vaccination and the effects on varicella epidemiology – results from the Bavarian Varicella Surveillance Project (BaVariPro), 2006-2011. BMC Infect Dis 13:303.

Zlamy M, Kofler S, Orth D, Würzner R, Heinz-Erian P, Streng A, Prelog M. (2013) The impact of Rotavirus mass vaccination on hospitalization rates, nosocomial Rotavirus gastroenteritis and secondary blood stream infections. BMC Infect Dis 13:112

2012

Brunner J, Prelog M, Riedl M, Giner T, Hofer J, Würzner R, Zimmerhackl LB. (2012) Analysis of the classical, alternative, and mannose binding lectin pathway of the complement system in the pathogenesis of oligoarticular juvenile idiopathic arthritis.
Rheumatol Int 32:1815-8.

Eltermann T, Wössner R, Liese J, Wieg C, Wirbelauer J, Thomas W. (2012) Fatal pertussis in a preterm with hyperleukocytosis and necrotizing enterocolitis: considerations on pathogenesis and prevention. Klin Padiatr. 224:461-2.

Graser S, Hofmann C, Jakob F, Mentrup B. (2012) Generation and characterization of a neuroblastoma cell line stably expressing the tissue-nonspecific alkaline phosphatase enzyme TNSALP. Bone. 50 1:S175-S176.

Hofmann SR, Morbach H, Schwarz T, Rösen-Wolff A, Girschick HJ, Hedrich CM. (2012) Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression. Clin Immunol 145:69-76.

Hofmann C, Schwarz T, Kunzmann S, Wirbelauer J, Beer M, Girschick H, Willascheck C, Buchhorn R, Kreher N, Plotkin H, Landy H, Liese J: Enzyme replacement therapy in different clinical phenotypes of hypophosphatasia – presentation of two cases.
Bull Group Int Rech Sci Stomatol Odontol 2012;51(1):e36.

Krudewig J, Baumann U, Bernuth von H, Borte M, Burkhard-Meier U, Dueckers G, Foerster-Waldl E, Franke K, Habermehl P, Hönig M, Kern W, Kösters K, Kugel K, Lehrnbecher T, Liese J, Marks R, Müller GA, Müller R, Nadal D, Peter HH, Pfeiffer-Kascha D, Schneider M, Sitter H, Späth P, Wahn V, Welte T, Niehues T. (2012) Interdisciplinary AWMF Guideline for the treatment of primary antibody deficiencies.  Klin Padiatr 224:404-15.

Lam TT, Claus H, Elias J, Hellenbrand W, Imöhl M, Prelog M, Sing A, van der Linden M, Vogel U. (2012) Infections with Pneumococci, Meningococci, H. influenza and Diphtheria in Germany: the RKI Reference Network for Invasive Bacterial Infections (IBI) at the 5th Würzburg Workshop on Epidemiology, Prevention and Therapy for Invasive Meningococcal Diseases 2010 (Meeting Report). Gesundheitswesen 74:747-53.

Mayerl C, Prelog M. (2012) Immunosenescence and juvenile idiopathic arthritis.
Autoimm Rev 1:297-300.

Mentrup B, Sabrautzki S, Hofmann C, de Angelis MH, Jakob F. (2012) In vitro characterization of TNSALP mutations from two novel mouse models for hypophosphatasia. Bone 50 1:S168-S168.

Morbach H, Schneider P, Schwarz T, Hofmann C, Raab P, Neubauer H, Düren C, Beer M, Girschick HJ. (2012) Comparison of magnetic resonance imaging and 99mTechnetium-labelled methylene diphosphonate bone scintigraphy in the initial assessment of chronic non-bacterial osteomyelitis of childhood and adolescents. Clin Exp Rheumatol 30:578-82.

Neubauer H, Evangelista L, Morbach H, Girschick H, Prelog M, Köstler H, Hahn D, Beer M. (2012) Diffusion-weighted MRI of bone marrow oedema, soft tissue oedema and synovitis in paediatric patients: feasibility and initial experience. Pediatr Rheumatol Online 10:20.

Neubauer H, Platzer I, Mueller VR, Meyer T, Liese J, Koestler H, Hahn D, Beer M. (2012) Diffusion-weighted MRI of abscess formations in children and young adults. World J Pediatr 8:229-34.

Roesler J, Segerer F, Morbach H, Kleinert S, Thieme S, Rösen-Wolff A, Liese JG. (2012) P67-phox (NCF2) lacking exons 11 and 12 is functionally active and leads to an extremely late diagnosis of chronic granulomatous disease (CGD). PLoS One 7:e34296.

Simon A, Mühlenborn E, Prelog M, Schenk W, Holzapfel J, Ebinger F, Klabunde-Cherwon A, Faber J, Groll A, Masjosthusmann K, Dohna-Schwake C, Beutel K, Lehrnbecher T, Ammann R, Müller A. (2012) Use of linezolid in neonatal and pediatric inpatient facilities-results of a retrospective multicenter survey. Eur J Clin Micr Infect Dis 31:1435-42.

Wieching A, Benser J, Kohlhauser-Vollmuth C, Weissbrich B, Streng A, Liese J. (2012) Clinical characteristics of pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Northern Bavaria, Germany. BMC Research Notes 5:304.

Zlamy M, Hofer J, Elias J, Vogel U, Frosch M, Jungraithmayr T, Zimmerhackl LB, Prelog M. (2012) Immunogenicity of meningococcus C vaccination in a patient with atipica hemolytic uremic syndrome (aHUS) on eculizumab therapy. Pediatr Transpl 16:E246-50.

2011

Beck C, Girschick HJ, Morbach H, Schwarz T, Frenkel J, van Gijn ME. (2011) Mutations of the IL-1 receptor antagonist gene are not associated with chronic nonbacterial osteomyelitis of childhood and adolescence. Clin Exp Rheumatol 29:1040-3.

Beck C, Morbach H, Wirth C, Beer M, Girschick HJ. (2011) Whole-body MRI in the childhood form of hypophosphatasia. Rheumatol Int. 31:1315-20.

Benser J, Streng A, Liese J. (2011) Bedeutung der Influenza im Kindesalter. Kinderärztl Praxis 82:28-30.

Farmand S, Baumann U, von Bernuth H, Borte M, Foerster-Waldl E, Franke K, Habermehl P, Kapaun P, Klock G, Liese J, Marks R, Müller R, Nebe T, Niehues T, Schuster V, Warnatz K, Witte T, Ehl S, Schulze I. (2011) Interdisciplinary AWMF guideline for the diagnostics of primary immunodeficiency. Klin Padiatr 223:378-85.

Guiso N, Liese J, Plotkin S. (2011) The Global Pertussis initiative: meeting report from the fourth regional roundtable meeting. Hum Vaccin 7:481-8.

Hofmann SR, Schwarz T, Möller JC, Morbach H, Schnabel A, Rösen-Wolff A, Girschick HJ, Hedrich CM. (2011) Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced IL10 promoter phosphorylation, and reduced myeloid IL-10 expression. Clin Immunol 141:317-27.

Kunze U, the ISW TBE (Prelog M et al.). (2011) Tick-borne encephalitis: the impact of epidemiology, changing lifestyle, and environmental factors. Conference report of the 12th Annual Meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE). Vaccine 29:1355-6.

Liese JG. (2011) Challenges in the differential diagnosis of aseptic meningo-encephalitis in children. Klin Padiatr 223:207-8.

Liese J. (2011) Pertussis. Eine Kinderkrankheit wird erwachsen und erfordert neue Präventionsstrategien. Kinder Jugendmed 3:144-6.

Mentrup B, Marschall C, Barvencik F, Amling M, Jakob F, Beck C. (2011) Functional characterization of a novel mutation localized in the start codon of the tissue-nonspecific alkaline phosphatase gene. Bone 48:1401-8.

Morbach H, Wiegering V, Richl P, Schwarz T, Suffa N, Eichhorn EM, Eyrich M, Girschick HJ. (2011) Activated memory B cells may function as antigen-presenting cells in the joints of children with juvenile idiopathic arthritis. Arthritis Rheum 63:3458-66.

Neubauer H, Morbach H, Schwarz T, Wirth C, Girschick HJ, Beer M. (2011) Popliteal cysts in paediatric patients: clinical characteristics and imaging features on ultrasound and MRI.
Arthritis 2011:751593.

Plotkin SA, Liese J, Madhi SA, Ortiz E. (2011) A DTaP-IPV//PRP~T vaccine (Pentaxim): a review of 16 years' clinical experience. Expert Rev Vaccines 10:981-1005.

Prelog M. (2011) Immune-aging and autoimmune disease in children. Curr Immunol Rev 7:116-23.

Prelog M, Schönlaub J, Zimmerhackl LB. (2011) Aciclovir and Varicella-zoster-immunoglobulin in solid organ transplant recipients. Pediatr Nephrol 26:663-73.

Rieber N, Graf A, Hartl D, Urschel S, Belohradsky BH, Liese J. (2011) Acellular pertussis booster in adolescents induces Th1 and memory CD8+ T cell immune response. PLoS One. 6:e17271.

Simões EA, Carbonell-Estrany X, Fullarton JR, Rossi GA, Barberi I, Lanari M; European RSV Risk Factor Study Group. (2011) European risk factors' model to predict hospitalization of premature infants born 33-35 weeks' gestational age with respiratory syncytial virus: validation with Italian data. J Matern Fetal Neonatal Med 24:152-7.

Streng A, Grote V, Liese JG. (2011) Severe influenza cases in paediatric intensive care units in Germany during the pre-pandemic seasons 2005 to 2008. BMC Infect Dis 11:233.

Von Kries R, Weiss S, Falkenhorst G, Wirth S, Kaiser P, Huppertz HI, Tenenbaum T, Schroten H, Streng A, Liese J, Shai S, Niehues T, Girschick H, Kuscher E, Sauerbrey A, Peters J, Wirsing von König CH, Rückinger S, Hampl W, Michel D, Mertens T. (2011) Post-pandemic seroprevalence of pandemic influenza A (H1N1) 2009 infection (swine flu) among children <18 years in Germany. PLoS One 6:e23955.

Weiß S, Streng A, Kries RV, Liese J, Wirth S, Jenke AC (2011) Incidence of intussusception in early infancy: a capture-recapture estimate for Germany. Klin Padiatr 223:419-423.

Wiegering V, Kaiser J, Tappe D, Weissbrich B, Morbach H, Girschick HJ. (2011) Gastroenteritis in childhood: a retrospective study of 650 hospitalized pediatric patients. Int J Infect Dis 15:e401-7.

Wiegering V, Schick J, Beer M, Weissbrich B, Gattenlöhner S, Girschick HJ, Liese J, Schlegel PG, Eyrich M: Varicella-zoster virus infections in immunocompromised patients - a single centre 6-years analysis. BMC Pediatr 2011;11:31.

Zlamy M, Elias J, Vogel U, Frosch M, Jeller V, Cortina G, Jungraithmayr T, Prelog M. (2011) Immunogenicity of conjugate Meningococcus C vaccine in pediatric solid organ transplant recipients. Vaccine 29:6163-.

2010

Albers HM, Brinkman DM, Kamphuis SS, van Suijlekom-Smit LW, van Rossum MA, Hoppenreijs EP, Girschick HJ, Wouters C, Saurenmann RK, Houwing-Duistermaat JJ, Huizinga TW, Schilham MW, ten Cate R. (2010) Clinical course and prognostic value of disease activity in the first two years in different subtypes of juvenile idiopathic arthritis.
Arthritis Care Res (Hoboken) 62:204-212.

Appay V, Sauce D, Prelog M. (2010) The role of the thymus in immunosenescence: lessons from the study of thymectomized individuals. Aging (Albany NY) 2:78-81.

Arguedas A, Kvaerner K, Liese J, Schilder AG, Pelton SI. (2010) Otitis media across nine countries: disease burden and management. Int J Pediatr Otorhinolaryngol 74:1419-1424.

Beck C, Morbach H, Beer M, Stenzel M, Tappe D, Gattenlohner S, Hofmann U, Raab P, Girschick HJ. (2010) Chronic nonbacterial osteomyelitis in childhood: prospective follow-up during the first year of anti-inflammatory treatment. Arthritis Res Ther 12:R74.

Beck C, Morbach H, Wirth C, Beer M, Girschick HJ. (2010) Whole-body MRI in the childhood form of hypophosphatasia. Rheumatol Int.

Brunner J, Moschovakis G, Prelog M, Walder G, Wuerzner R, Zimmerhackl LB. (2010) Lyme neuroborreliosis: aetiology and diagnosis of facial palsy in children from Tyrol.
Klin Padiatr 222:302-307.

Carbonell-Estrany X, Simões EA, Dagan R, Hall CB, Harris B, Hultquist M, Connor EM, Losonsky GA; Motavizumab Study Group. (2010) Motavizumab for prophylaxis of respiratory syncytial virus in high-risk children: a noninferiority trial. Pediatrics 125:e35-51.

Humrich JY, Morbach H, Undeutsch R, Enghard P, Rosenberger S, Weigert O, Kloke L, Heimann J, Gaber T, Brandenburg S, Scheffold A, Huehn J, Radbruch A, Burmester GR, Riemekasten G. (2010) Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus. Proc Natl Acad Sci U S A 107:204-209.

Kohl LJ, Streng A, Grote V, Koletzko S, Liese JG. (2010) Intussusception-associated hospitalisations in southern Germany. Eur J Pediatr 169:1487-1493.

Kümmerle-Deschner JB, Tyrrell PN, Reess F, Kötter I, Lohse P, Girschick H, Huemer C, Horneff G, Haas JP, Koitschev A, Deuter C, Benseler SM. (2010) Risk factors for severe Muckle-Wells syndrome. Arthritis Rheum 62:3783-91.

Liese JG, Rieber N, Malzer T, Ocak M, Johnson DR, Decker MD. (2010) Reactogenicity of tetanus, diphtheria, 5-component acellular pertussis vaccine administered as a sixth consecutive acellular pertussis vaccine dose to adolescents. Pediatr Infect Dis J 29:1067-1071.

Morbach H, Dannecker H, Kerkau T, Girschick HJ. (2010) Prevalence of antibodies against mutated citrullinated vimentin and cyclic citrullinated peptide in children with juvenile idiopathic arthritis. Clin Exp Rheumatol 28:800.

Morbach H, Dick A, Beck C, Stenzel M, Muller-Hermelink HK, Raab P, Girschick HJ. (2010) Association of chronic non-bacterial osteomyelitis with Crohn's disease but not with CARD15 gene variants. Rheumatol Int 30:617-621.

Morbach H, Eichhorn EM, Liese JG, Girschick HJ. (2010) Reference values for B cell subpopulations from infancy to adulthood. Clin Exp Immunol 162:271-279.

Mornet E, Beck C, Bloch-Zupan A, Girschick H, Le Merrer M. (2010) Clinical utility gene card for: hypophosphatasia. Eur J Hum Genet 19.

Prelog M, Zimmerhackl LB. (2010) Varicella vaccination in pediatric kidney and liver transplantation. Pediatr Transplant 14:41-47.

Rack AL, Grote V, Streng A, Belohradsky BH, Heinen F, von Kries R, Liese JG. (2010) Neurologic varicella complications before routine immunization in Germany. Pediatr Neurol 42:40-48.

Stoevesandt J, Morbach H, Martin TM, Zierhut M, Girschick H, Hamm H. (2010) Sporadic Blau syndrome with onset of widespread granulomatous dermatitis in the newborn period. Pediatr Dermatol 27:69-73.

Streng A, Seeger K, Grote V, Liese JG. (2010) Varicella vaccination coverage in Bavaria (Germany) after general vaccine recommendation in 2004. Vaccine 28:5738-5745.

Vergison A, Dagan R, Arguedas A, Bonhoeffer J, Cohen R, Dhooge I, Hoberman A, Liese J, Marchisio P, Palmu AA, Ray GT, Sanders EA, Simoes EA, Uhari M, van Eldere J, Pelton SI. (2010) Otitis media and its consequences: beyond the earache. Lancet Infect Dis 10: 195-203.

von Chamier G, Holl-Wieden A, Stenzel M, Raab P, Darge K, Girschick HJ, Beer M. (2010) Pitfalls in diagnostics of hip pain: osteoid osteoma and osteoblastoma. Rheumatol Int 30:395-400.

Wiegering V, Balling G, Wirbelauer J, Sturm A, Girschick HJ. (2010) Post varicella disseminated intravascular coagulation and transient protein S deficiency in an otherwise healthy 6-year-old boy: a case report. Infection 38:505-508.

Wiegering V, Girschick HJ, Morbach H (2010): B-cell pathophysiology in juvenile idiopathic arthritis. Arthritis Article ID 759868.

Wiegering V, Morbach H, Dick A, Girschick HJ. (2010) Crohn's disease during etanercept therapy in juvenile idiopathic arthritis: a case report and review of the literature. Rheumatol Int 30:801-804.

Zlamy M, Wurzner R, Holzmann H, Brandstatter A, Jeller V, Zimmerhackl LB, Prelog M. (2010) Antibody dynamics after tick-borne encephalitis and measles-mumps-rubella vaccination in children post early thymectomy. Vaccine 28:8053-8060. 

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