Publikationen Pädiatrische Rheumatologie, Infektiologie, Immunologie

2022

Dirks J, Haase G, Cantaert T, Frey L, Klaas M, Rickert CH, Girschick H, Meffre E, Morbach H (2022) 
A novel AICDA splice-site mutation in two siblings with HIGM2 permits somatic hypermutation but abrogates mutational targeting. 
J Clin Immunol 2022;42(4):771-782. 

Engels G, Döhler B, Tönshoff B, Oh J, Kruchen A, Müller I and Süsal C (2022) 
Maternal versus paternal living kidney transplant donation is associated with lower rejection in young pediatric recipients: A Collaborative Transplant Study report. 
Pediatr Transplant. 2022; 26:e14154. doi.org/10.1111/petr.14154

Engels G, Sack J, Weissbrich B, Hartmann K, Knies K, Härtel C, Streng A, Dälken L, Liese J, for the CoPraKid Study Group (2022) 
Very low incidence of SARS-CoV-2, influenza and RSV but high incidence of rhino-, adeno- and endemic coronaviruses in children with acute respiratory infection in primary care pediatric practices during the second and third wave of the SARS-CoV-2 pandemic.
Pediatr Infect Dis 2022;41(4):e146-e148  doi: 10.1097/INF.0000000000003460

Fischer J, Dirks J, Klaussner J, Haase G, Holl-Wieden A, Hofmann C, Hackenberg S, Girschick H, Morbach H (2021) 
Effect of clonally expanded PD-1highCXCR5-CD4+ peripheral T helper cells on B cell differentiation in the joints of patients with antinuclear, antibody-positive juvenile idiopathic arthritis. 
Arthritis Rheumatol 2022;74(1):150-162. 

Forster J, Streng A, Rudolph P, Rücker V, Wallstabe J, Timme S, Pietsch F, Hartmann K, Krauthausen M, Schmidt J, Ludwig T, Gierszewski D, Jans T, Engels G, Weißbrich B, Romanos M, Dölken L, Heuschmann P, Härtel C, Gágyor I, Figge MT, Kurzai O, Liese J; Wü-KiTa-CoV Study Group (2022) 
Feasibility of SARS-CoV-2 surveillance testing among children and childcare workers at German day care centres: A nonrandomized controlled trial. 
JAMA Netw Open 2022;5(1):e2142057.

Gierszewski D, Kurotschka PK, Krauthausen M, Fröhlich W, Forster J, Pietsch F, Streng A, Rücker V, Wallstabe J, Hartmann K, Jans T, Engels G, Romanos M, Heuschmann P, Härtel C, Kurzai O, Liese J, Gágyor I (2022) 
Parents' and childcare workers' perspectives toward SARS-CoV-2 test and surveillance protocols in pre-school children day care centres: A qualitative study within the German Wü-KiTa-CoV project. 
Front Med (Lausanne) 2022;9:897726.

Goettler D, Niekler P, Liese JG, Streng A (2022) 
Epidemiology and direct healthcare costs of Influenza-associated hospitalizations - nationwide inpatient data (Germany 2010-2019). 
BMC Public Health 2022;22(1):108. 

Hartmann K, Liese JG, Kemmling D, Prifert C, Weißbrich B, Thilakarathne P, Diels J, Weber K, Streng A (2022) 
Clinical burden of respiratory syncytial virus in hospitalized children aged ≤5 years (INSPIRE Study). 
J Infect Dis 2022;jiac137.  

Holzer MT, Almanzar G, Woidich R, Hügle B, Haas JP, Prelog M (2022) 
Mitigated suppressive function of regulatory T cells (Treg) upon Th17-inducing cytokines in oligo- and polyarticular Juvenile Idiopathic Arthritis (JIA) patients. 
Pediatr Rheumatol Online J 2022;20(1):26. 

Papan C, Argentiero A, Porwoll M, Hakim U, Farinelli E, Testa I, Pasticci MB, Mezzetti D, Perruccio K, Etshtein L, Mastboim N, Moscoviz E, Ber TI, Cohen A, Simon E, Boico O, Shani L, Gottlieb TM, Navon R, Barash E, Oved K, Eden E, Simon A, Liese JG, Knuf M, Stein M, Yacobov R, Bamberger E, Schneider S, Esposito S, Tenenbaum T (2022) 
A host signature based on TRAIL, IP-10, and CRP for reducing antibiotic overuse in children by differentiating bacterial from viral infections: a prospective, multicentre cohort study. 
Clin Microbiol Infect 2022;28(5):723-730.

Papan C, Reifenrath K, Last K, Attarbaschi A, Graf N, Groll AH, Huebner J, Laws HJ, Lehrnbecher T, Liese J, Martin L, Tenenbaum T, Weichert S, Vieth S, von Both U, Hufnagel M, Simon A (2022) 
Antimicrobial use in pediatric oncology and hematology: Protocol for a multicenter point-prevalence study with qualitative expert panel assessment. JMIR Res Protoc 2022;11(6):e35774. 

Pfeil J; DGPI, Assaad K; BVÖGD, von Both U; DAKJ/Bündnis Kinder- und Jugendgesundheit, Janda A, Kitz C, Kobbe R; GTP, Kunze M; DGGG, Lindert J; DGKCH, Ritz N; PIGS, Trapp S; BVKJ, Hufnagel M; DGKJ (2022) 
Aktualisierte Empfehlungen zur infektiologischen Versorgung von Flüchtlingen im Kindes- und Jugendalter in Deutschland (Stand 30. März 2022), angemeldet als S1-Leitlinie (AWMF-Register Nr. 048-017): Stellungnahme der Deutschen Gesellschaft für Pädiatrische Infektiologie e. V. (DGPI), der Gesellschaft für Tropenpädiatrie und Internationale Kindergesundheit e. V. (GTP), des Berufsverbandes der Kinder- und Jugendärzte e. V. (BVKJ) und der Deutschen Gesellschaft für Kinder- und Jugendmedizin e. V. (DGKJ), unter Mitarbeit des Berufsverbands der Ärztinnen und Ärzte des Öffentlichen Gesundheitsdienstes e. V. (BVÖGD), der Deutschen Gesellschaft für Kinderchirurgie e. V. (DGKCH), der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe e. V. (DGGG), Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin (DEGAM), des Bündnis Kinder- und Jugendgesundheit e. V. (früher Deutsche Akademie für Kinder- und Jugendmedizin, DAKJ), der Deutschen Gesellschaft für Tropenmedizin, Reisemedizin und Globale Gesundheit e. V. (DTG), der Deutschen Gesellschaft für Globale und Tropenchirurgie e. V. (DTC) und der Pädiatrisch Infektiologischen Gruppe Schweiz (PIGS) [Updated recommendations on the treatment of infectious diseases in refugees in childhood and adolescence in Germany (situation as of 30 March 2022), registered as S1 guidelines (AWMF-Register Nr. 048-017)]. 
Monatsschr Kinderheilkd 2022;170(7):632-647. [Liese J Collaborator]

Sonnleitner ST, Prelog M, Jansen B, Rodgarkia-Dara C, Gietl S, Schönegger CM, Koblmüller S, Sturmbauer C, Posch W, Almanzar G, Jury H, Loney T, Tichy A, Nowotny N, Walder G (2022) 
Maintenance of neutralizing antibodies over ten months in convalescent SARS-CoV-2 afflicted patients. 
Transbound Emerg Dis 2022;69(3):1596-1605. 

Sonnleitner ST*, Prelog M*, Sonnleitner S, Hinterbichler E, Halbfurter H, Kopecky DBC, Almanzar G, Koblmüller S, Sturmbauer C, Feist L, Horres R, Posch W, Walder G (2022)
Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host.
Nat Commun 2022;13(1):2560. *shared first author

Sorg AL, Bergfeld L, Jank M, Corman V, Semmler I, Goertz A, Beyerlein A, Verjans E, Wagner N, Von Bernuth H, Lander F, Weil K, Hufnagel M, Spiekerkoetter U, Chao CM, Naehrlich L, Muntau AC, Schulze-Sturm U, Hansen G, Wetzke M, Jung AM, Niehues T, Fricke-Otto S, Von Both U, Huebner J, Behrends U, Liese JG, Schwerk C, Drosten C, Von Kries R, Schroten H (2022) 
Cross-sectional seroprevalence surveys of SARS-CoV-2 antibodies in children in Germany, June 2020 to May 2021. 
Nat Commun 2022;13(1):3128. 

Streng A, Prifert C, Weissbrich B, Sauerbrei A, Krumbholz A, Schmidt-Ott R, Liese JG (2022)
Similar severity of influenza primary and re-infections in pre-school children requiring outpatient treatment due to febrile acute respiratory illness: prospective, multicentre surveillance study (2013-2015). 
BMC Infect Dis 2022;22(1):12. 

Wratil PR, Stern M, Priller A, Willmann A, Almanzar G, Vogel E, Feuerherd M, Cheng CC, Yazici S, Christa C, Jeske S, Lupoli G, Vogt T, Albanese M, Mejías-Pérez E, Bauernfried S, Graf N, Mijocevic H, Vu M, Tinnefeld K, Wettengel J, Hoffmann D, Muenchhoff M, Daechert C, Mairhofer H, Krebs S, Fingerle V, Graf A, Steininger P, Blum H, Hornung V, Liebl B, Überla K, Prelog M, Knolle P, Keppler OT, Protzer U (2022) 
Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern. 
Nat Med  2022;28(3):496-503. 

2021

Forster J, Piazza G, Goettler D, Kemmling D, Schoen C, Rose M, Streng A, Liese JG (2021) 
Effect of prehospital antibiotic therapy on clinical outcome and pathogen detection in children with parapneumonic pleural effusion/pleural empyema. 
Pediatr Infect Dis J 2021;40(6):544-549. 

Harasim AS, Krone M, Tony HP, Gawlik M, Witte T, Joos S, Gernert M, Schmalzing M, Morbach H, Schwaneck EC (2021) 
Use of complementary and alternative medicine in patients with primary immunodeficiency: A multicentric analysis of 101 patients. 
J Clin Immunol 2021;41(3):585-594.

Heim J, Almanzar G, Schmalzing M, Gernert M, Tony HP, Prelog M (2021) 
Induction of IL-9 in peripheral lymphocytes of rheumatoid arthritis patients and healthy donors by Th17-inducing cytokine conditions. 
Front Immunol 2021;12:668095. 

Kenntner S, Liese JG (2021) 
So impfen Sie Kinder und Jugendliche völlig stressfrei [Update on STIKO vaccination recommendations for children]. 
MMW Fortschr Med 2021;163(10):38-41. 

Kurotschka PK, Tiedemann E, Wolf D, Thier N, Forster J, Liese JG, Gagyor I (2021) 
Management of common infections in German primary care: A cross-sectional survey of knowledge and confidence among general practitioners and outpatient pediatricians.
Antibiotics (Basel) 2021;10(9):1131. 

Liang C, Bencurova E, Psota E, Neurgaonkar P, Prelog M, Scheller C, Dandekar T (2021) 
Population-predicted MHC class II epitope presentation of SARS-CoV-2 structural proteins correlates to the case fatality rates of COVID-19 in different countries. 
Int J Mol Sci 2021;22(5):2630. 

Prelog M, Almanzar G, Stern R, Robrade K, Holzer MT, Winzig C, Kleines M, Stiasny K, Meyer T, Speth F, Haas JP (2021) 
Humoral and cellular immune response to tick-borne-encephalitis (TBE) vaccination depends on booster doses in patients with Juvenile Idiopathic Arthritis (JIA). 
Vaccine 2021;39(40):5918-5927. 

Röbl-Mathieu M, Kunstein A, Liese J, Mertens T, Wojcinski M (2021) 
Vaccination in pregnancy. 
Dtsch Arztebl Int 2021;118(15):262-268. 

Schaal MC, Gendler L, Ammann B, Eberhardt N, Janda A, Morbach H, Darge K, Girschick H, Beer M (2021) 
Imaging in non-bacterial osteomyelitis in children and adolescents: diagnosis, differential diagnosis and follow-up-an educational review based on a literature survey and own clinical experiences. 
Insights Imaging 2021;12(1):113. 

Schlag S, Liese J, Veldhoen S (2021) 
Akutes Abdomen mit galligem Erbrechen – Ein Leinsamen-Bezoar als ungewöhnliche Ursache eines obstruktiven Ileus bei einer Adoleszenten mit Anorexie [Acute abdomen with bilious vomiting - a linseed Bezoar as a rare cause of an obstructive ileus in an anorexic adolescent]. 
Klin Padiatr 2021;233(2):72-74. 

Sorg AL, Obermeier V, Liese JG, von Kries R (2021) 
Incidence trends of parapneumonic pleural effusions/empyema in children 2009 to 2018 from health insurance data: Only temporal reduction after the introduction of PCV13. 
Vaccine 2021;39(26):3516-3519.

Thalhammer J, Kindle G, Nieters A, Rusch S, Seppänen MRJ, Fischer A, Grimbacher B, Edgar D, Buckland M, Mahlaoui N, Ehl S; European Society for Immunodeficiencies Registry Working Party (2021) 
Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations. 
J Allergy Clin Immunol 2021;148(5):1332-1341.

Wagenhäuser I, Knies K, Rauschenberger V, Eisenmann M, McDonogh M, Petri N, Andres O, Flemming S, Gawlik M, Papsdorf M, Taurines R, Böhm H, Forster J, Weismann D, Weißbrich B, Dölken L, Liese J, Kurzai O, Vogel U, Krone M (2021) 
Clinical performance evaluation of SARS-CoV-2 rapid antigen testing in point of care usage in comparison to RT-qPCR. 
EBioMedicine. 2021;69:103455. 

2020

Bundesverband Deutscher Krankenhausapotheker e. V. (ADKA); Deutsche Gesellschaft für Hygiene und Mikrobiologie e. V. (DGHM); Deutsche Gesellschaft für Infektiologie e. V. (DGI); Deutsche Gesellschaft für Krankenhaushygiene e. V. (DGKH); Deutsche Gesellschaft für Pädiatrische Infektiologie e. V. (DGPI); Kommission Antiinfektiva, Resistenz und Therapie (Kommission ART) beim Robert Koch-Institut; Paul-Ehrlich-Gesellschaft für Chemotherapie e. V. (PEG); Robert Koch-Institut, Geschäftsstelle der Kommission ART (2020)
Strukturelle und personelle Voraussetzungen für die Sicherung einer rationalen Antiinfektivaverordnung in Krankenhäusern : Positionspapier der Kommission Antiinfektiva, Resistenz und Therapie (Kommission ART) beim Robert Koch-Institut mit Beratung durch Fachgesellschaften [Organisational and staff requirements for antimicrobial stewardship activities in hospitals : Position paper of the Commission on Anti-Infectives, Resistance and Therapy (Commission ART) at the Robert Koch Institute, with advice from professional associations].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2020;63(6):749-760. (Liese J: Collaborator)

Fischer J, Dirks J, Haase G, Holl-Wieden A, Hofmann C, Girschick H, Morbach H (2020) 
IL 21+ CD4+ T helper cells co-expressing IFN-γ and TNF-α accumulate in the joints of antinuclear antibody positive patients with juvenile idiopathic arthritis.
Clin Immunol. 2020;217:108484.. 

Froehlich M, Schwaneck EC, Gernert M, Gadeholt O, Strunz PP, Morbach H, Tony HP, Schmalzing M (2020)
Autologous Stem Cell Transplantation in Common Variable Immunodeficiency: A Case of Successful Treatment of Severe Refractory Autoimmune Encephalitis.
Front Immunol. 2020;11:1317.

Goettler D, Streng A, Kemmling D, Schoen C, von Kries R, Rose MA, van der Linden M, Liese JG (2020)
Increase in Streptococcus pneumonia serotype 3 associated parapneumonic pleural effusion/empyema after the introduction of PCV13 in Germany.
Vaccine. 2020;38(3):570-577.

Hanitsch L, Baumann U, Boztug K, Burkhard-Meier U, Fasshauer M, Habermehl P, Hauck F, Klock G, Liese J, Meyer O, Müller R, Pachlopnik-Schmid J, Pfeiffer-Kascha D, Warnatz K, Wehr C, Wittke K, Niehues T, von Bernuth H (2020)
Treatment and management of primary antibody deficiency: German interdisciplinary evidence-based consensus guideline.
Eur J Immunol. 2020;50(10):1432-1446.

Hansmann S, Lainka E, Horneff G, Holzinger D, Rieber N, Jansson AF, Rösen-Wolff A, Erbis G, Prelog M, Brunner J, Benseler SM, Kuemmerle-Deschner JB (2020)
Consensus protocols for the diagnosis and management of the hereditary autoinflammatory syndromes CAPS, TRAPS and MKD/HIDS: a German PRO-KIND initiative.
Pediatr Rheumatol Online J 2020;18(1):17.

Hedrich CM, Morbach H, Reiser C, Girschick HJ (2020)
New Insights into Adult and Paediatric Chronic Non-bacterial Osteomyelitis CNO.
Curr Rheumatol Rep. 2020;22(9):52.

Kühnemundt J, Leifeld H, Scherg F, Schmitt M, Nelke LC, Schmitt T, Baur F, Göttlich C, Fuchs M, Kunz M, Peindl M, Brähler C, Kronenthaler C, Wischhusen J, Prelog M, Walles H, Dandekar T, Dandekar G, Nietzer SL (2020)
Modular micro-physiological human tumor/tissue models based on decellularized tissue for improved preclinical testing.
ALTEX. 2020;38(2):289-306.

Kuntz M, Kohlfürst DS, Feiterna-Sperling C, Krüger R, Baumann U, Buchtala L, Elling R, Grote V, Hübner J, Hufnagel M, Kaiser-Labusch P, Liese J, Otto EM, Rose MA, Schneider C, Schuster V, Seidl M, Sommerburg O, Vogel M, von Bernuth H, Weiß M, Zimmermann T, Nieters A, Zenz W, Henneke P; NTMkids Consortium (2020)
Risk Factors for Complicated Lymphadenitis Caused by Nontuberculous Mycobacteria in Children.
Emerg Infect Dis. 2020;26(3):579-586.

Li MX, Sauer A, Holl-Wieden A, Pabst T, Neubauer H (2020)
Diagnostic value of diffusion-weighted MRI for imaging synovitis in pediatric patients with inflammatory conditions of the knee joint.
World J Pediatr 2020;16(1):60-67.

Morbach H, Naumann-Bartsch N, Oommen PT, Schulz A, Seidemann K, Speckmann C, Sykora KW, von Kries R, Niehues T (2020) 
Incidence of SCID in Germany from 2014 to 2015 an ESPED* Survey on Behalf of the API*** Erhebungseinheit für Seltene Pädiatrische Erkrankungen in Deutschland (German Paediatric Surveillance Unit) ** Arbeitsgemeinschaft Pädiatrische Immunologie.
J Clin Immunol. 2020;(5):708-717.

Prelog M (2020) 
Treg and Th17 cells: kinship with consequences.
Arthritis und Rheuma. 2020;40:118-123.

Rose MA, Barker M, Liese J, Adams O, Ankermann T, Baumann U, Brinkmann F, Bruns R, Dahlheim M, Ewig S, Forster J, Hofmann G, Kemen C, Lück C, Nadal D, Nüßlein T, Regamey N, Riedler J, Schmidt S, Schwerk N, Seidenberg J, Tenenbaum T, Trapp S, van der Linden M (2020)
S2k-Leitlinie Management der ambulant erworbenen Pneumonie bei Kindern und Jugendlichen (pädiatrische ambulant erworbene Pneumonie, pCAP) [Guidelines for the Management of Community Acquired Pneumonia in Children and Adolescents (Pediatric Community Acquired Pneumonia, pCAP) - Issued under the Responsibility of the German Society for Pediatric Infectious Diseases (DGPI) and the German Society for Pediatric Pulmonology (GPP)].
Pneumologie. 2020;74(8):515-544.

Schnabel A, Unger E, Brück N, Berner R, Range U, Holl-Wieden A, Morbach H, Leszczynska A, Bau V, Hedrich CM (2020)
High-dose intravenous methylprednisolone in juvenile non-infectious uveitis: A retrospective analysis.
Clin Immunol. 2020;211:108327. 

Seitel T, Cagol L, Prelog M, Frivolt K, Krahl A, Trenkel S, Speth F, Mayer B, Almanzar G, Koletzko S, Debatin KM, Mertens T, Posovszky C (2020)
Varicella-zoster-virus vaccination of immunosuppressed children with inflammatory bowel disease or autoimmune hepatitis: A prospective observational study.
Vaccine. 2020;38(50):8024-8031.

Shai S, Perez-Becker R, Andres O, Bakhtiar S, Bauman U, von Bernuth H, Classen CF, Dückers G, El-Helou SM, Gangfuß A, Ghosh S, Grimbacher B, Hauck F, Hoenig M, Husain RA, Kindle G, Kipfmueller F, Klemann C, Krüger R, Lainka E, Lehmberg K, Lohrmann F, Morbach H, Naumann-Bartsch N, Oommen PT, Schulz A, Seidemann K, Speckmann C, Sykora KW, von Kries R, Niehues T (2020)
Incidence of SCID in Germany from 2014 to 2015 an ESPED* Survey on Behalf of the API*** Erhebungseinheit für Seltene Pädiatrische Erkrankungen in Deutschland (German Paediatric Surveillance Unit) ** Arbeitsgemeinschaft Pädiatrische Immunologie.
J Clin Immunol 2020;(5):708-717.

Streng A, Hartmann K, Armann J, Berner R, Liese JG (2020)
COVID-19 bei hospitalisierten Kindern und Jugendlichen [COVID-19 in hospitalized children and adolescents].
Monatsschr Kinderheilkd 2020;168:615-627.

2019

Almanzar G, Kienle F, Schmalzing M, Maas A, Tony HP, Prelog M (2019) Tofacitinib modulates the VZV-specific CD4+ T cell immune response in vitro in lymphocytes of patients with rheumatoid arthritis. Rheumatology (Oxford). 2019;58:2051-2060.

Almanzar G, Schmalzing M, Klein M, Hilligardt D, Morris P, Höfner K, El Hajj N, Kneitz H, Wild V, Rosenwald A, Benout S, Hamm H, Tony HP, Haaf T, Goebeler M, Prelog M (2019) Memory CD4+ T cells which lacking expression of CCR7 promote pro-inflammatory cytokine production in patients with diffuse cutaneous systemic sclerosis (dcSSc). Eur J Dermatol 2019;29:468-476.

Ehl S, Bogdan C, Niehues T, Burchard G, Baumann U, Hecht J, et al (2019) Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019;623:378.

El-Helou SM, Biegner AK, Bode S, Ehl SR, Heeg M, Maccari ME, Ritterbusch H, Speckmann C, Rusch S, Scheible R, Warnatz K, Atschekzei F, Beider R, Ernst D, Gerschmann S, Jablonka A, Mielke G, Schmidt RE, Schürmann G, Sogkas G, Baumann UH, Klemann C, Viemann D, von Bernuth H, Krüger R, Hanitsch LG, Scheibenbogen CM, Wittke K, Albert MH, Eichinger A, Hauck F, Klein C, Rack-Hoch A, Sollinger FM, Avila A, Borte M, Borte S, Fasshauer M, Hauenherm A, Kellner N, Müller AH, Ülzen A, Bader P, Bakhtiar S, Lee JY, Heß U, Schubert R, Wölke S, Zielen S, Ghosh S, Laws HJ, Neubert J, Oommen PT, Hönig M, Schulz A, Steinmann S, Schwarz K, Dückers G, Lamers B, Langemeyer V, Niehues T, Shai S, Graf D, Müglich C, Schmalzing MT, Schwaneck EC, Tony HP, Dirks J, Haase G, Liese JG, Morbach H, Foell D, Hellige A, Wittkowski H, Masjosthusmann K, Mohr M, Geberzahn L, Hedrich CM, Müller C, Rösen-Wolff A, Roesler J, Zimmermann A, Behrends U, Rieber N, Schauer U, Handgretinger R, Holzer U, Henes J, Kanz L, Boesecke C, Rockstroh JK, Schwarze-Zander C, Wasmuth JC, Dilloo D, Hülsmann B, Schönberger S, Schreiber S, Zeuner R, Ankermann T, von Bismarck P, Huppertz HI, Kaiser-Labusch P, Greil J, Jakoby D, Kulozik AE, Metzler M, Naumann-Bartsch N, Sobik B, Graf N, Heine S, Kobbe R, Lehmberg K, Müller I, Herrmann F, Horneff G, Klein A, Peitz J, Schmidt N, Bielack S, Groß-Wieltsch U, Classen CF, Klasen J, Deutz P, Kamitz D, Lassay L, Tenbrock K, Wagner N, Bernbeck B, Brummel B, Lara-Villacanas E, Münstermann E, Schneider DT, Tietsch N, Westkemper M, Weiß M, Kramm C, Kühnle I, Kullmann S, Girschick H, Specker C, Vinnemeier-Laubenthal E, Haenicke H, Schulz C, Schweigerer L, Müller TG, Stiefel M, Belohradsky BH, Soetedjo V, Kindle G, Grimbacher B (2019) The German National Registry of Primary Immunodeficiencies (2012-2017). Front Immunol. 2019 Jul 19;10:1272.

Hagemann C, Krämer A, Grote V, Liese JG, Streng A (2019) Specific Varicella-Related Complications and Their Decrease in Hospitalized Children after the Introduction of General Varicella Vaccination: Results from a Multicenter Pediatric Hospital Surveillance Study in Bavaria (Germany). Infect Dis Ther. 2019;84:597-611.

Hetzer B, Orth-Höller D, Würzner R, Kreidl P, Lackner M, Müller T, Knabl L, Geisler-Moroder DR, Mellmann A, Sesli Ö, Holzknecht J, Noce D, Boonpala O, Akarathum N, Chotinaruemol S, Prelog M, Oberdorfer P (2019) Enhanced acquisition of antibiotic-resistant intestinal E. coli during the first year of life assessed in a prospective cohort study. Antimicrob Resist Infect Control. 2019;8:79.

Hofmann CE, Harmatz P, Vockley J, Högler W, Nakayama H, Bishop N, et al (2019) Efficacy and Safety of Asfotase Alfa in Infants and Young Children With Hypophosphatasia: A Phase 2 Open-Label Study. J Clin Endocrinol Metab. 2019;1047:2735-47.

Ickrath P, Morbach H, Schwaneck EC, Gehrke T, Scherzad A, Hagen R, Hackenberg S (2019) Rezidivierende Infektionen bei Patienten mit primären Immundefekten im oberen Aerodigestivtrakt [Recurrent infections of the upper aerodigestive tract in patients with primary immunodeficiency]. HNO 2019;67(11):819-824.

Liese JG, Schoen C, van der Linden M, Lehmann L, Goettler D, Keller S, et al (2019) Changes in the incidence and bacterial aetiology of paediatric parapneumonic pleural effusions/empyema in Germany, 2010-2017: a nationwide surveillance study. Clin Microbiol Infect. 2019;257:857-64.

Nothhaft M, Klepper J, Kneitz H, Meyer T, Hamm H, Morbach H (2019) Hemorrhagic Bullous Henoch-Schönlein Purpura: Case Report and Review of the Literature. Front Pediatr. 2019 Jan 22;6:413.

Schnabel A, Unger E, Brück N, Berner R, Range U, Holl-Wieden A, Morbach H, Leszczynska A, Bau V, Hedrich CM (2019) High-dose intravenous methylprednisolone in juvenile non-infectious uveitis: A retrospective analysis. Clin Immunol. 2020 Feb;211:108327. doi: 10.1016/j.clim.2019.108327. Epub 2019 Dec 18.

Spoulou V, Alain S, Gabutti G, Giaquinto C, Liese J, Martinon-Torres F, et al (2019) Implementing Universal Varicella Vaccination in Europe: The Path Forward. Pediatr Infect Dis J. 2019;382:181-8.

Streng A, Goettler D, Haerlein M, Lehmann L, Ulrich K, Prifert C, et al (2019) Spread and clinical severity of respiratory syncytial virus A genotype ON1 in Germany, 2011-2017. BMC Infect Dis. 2019;191:613.

Whyte MP, Leung E, Wilcox WR, Liese J, Argente J, Martos-Moreno G, et al (2019) Natural History of Perinatal and Infantile Hypophosphatasia: A Retrospective Study. J Pediatr. 2019;209:116-24.e4.

2018

Brandt D, Sohr E, Pablik J, Schnabel A, Kapplusch F, Mäbert K, Girschick JH, Morbach H, Thielemann F, Hofmann SR, Hedrich CM (2018) CD14+ monocytes contribute to inflammation in chronic nonbacterial osteomyelitis (CNO) through increased NLRP3 inflammasome expression. Clin Immunol 2018;196:77-84

Klenke D, Quast A, Prelog M, Holl-Wieden A, Riekert M, Stellzig-Eisenhauer A, Meyer-Marcotty P (2018) TMJ pathomorphology in patients with JIA-radiographic parameters for early diagnosis. Head Face Med 2018;14:15

Köstner K, Prelog M, Almanzar G, Fesq H, Haas JP, Hügle B (2018) Successful use of secukinumab in a 4-year-old patient with deficiency of interleukin-36 antagonist. Rheumatology (Oxford) 2018;57:936-938

Liese JG, Schoen C, van der Linden M, Lehmann L, Goettler D, Keller S, Maier A, Segerer F, Rose MA, Streng A (2018) Changes in the incidence and bacterial aetiology of paediatric parapneumonic pleural effusions/empyema in Germany, 2010-2017: A nationwide surveillance study. Clin Microbiol Infect 2018 doi: 10.1016/j.cmi.2018.10.020 [Epub ahead of print]

Omeñaca F, Vázquez L, Garcia-Corbeira P, Mesaros N, Hanssens L, Dolhain J, Puente Gómez I, Liese JG, Knuf M (2018) Immunization of preterm infants with GSK’s hexavalent combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type b conjugate vaccine: A review of safety and immunogenicity. Vaccine 2018;36:986-996

Spoulou V, Alain S, Gabutti G, Giaquinto C, Liese J, Martinon-Torres F, Vesikari T (2018)(2018) Implementing universal varicella vaccination in Europe. The path forward. Pediatr Infect Dis J 2019;38:181-188

Streng A, Prifert C, Weissbrich B, Sauerbrei A, Schmidt-Ott R, Liese JG (2018) Subtype-specific clinical presentation, medical treatment and family impact of influenza in children 1-5 years of age treated in outpatient practices in Germany during three postpandemic years, 2013-2015. Pediatr Infect Dis J 2018;37:861-867

2017

Carbonell-Estrany X, Fullarton JR, Gooch KL, Gouyon J-B, Lanari M, Rodgers-Gray BS, Thwaites RJ, Vo PG, Liese JG. (2017) The influence of birth weight amongst 33-35 weeks gestational age (wGA) infants on the risk of respiratory syncytial virus (RSV) hospitalisation: a pooled analysis. J Matern Fetal Neonatal Med 30(2):134-140.

Hagemann C, Seeger K, Krämer A, Liese JG, Streng A. (2017) Entwicklung der Varizellen-Impfraten und mögliche Einflussfaktoren auf die Impfentscheidung der Eltern im Münchner Raum in den Jahren 2009-201 nach Einführung der allgemeinen Varizellenimpfung. Gesundheitswesen 79(4):286-295.

Hagemann C, Streng A, Kraemer A, Liese JG. (2017) Heterogeneity in coverage for measles and varicella vaccination in toddlers – analysis of factors influencing parental acceptance. BMC Public Health 17:724.

Hofmann SR, Böttger F, Range U, Lück C, Morbach H, Girschick HJ, Suttorp M, Hedrich CM. (2017) Serum Interleukin-6 and CCL11/Eotaxin May Be Suitable Biomarkers for the Diagnosis of Chronic Nonbacterial Osteomyelitis. Front Pediatr 5:256.

Hofmann SR, Kapplusch F, Girschick HJ, Morbach H, Pablik J, Ferguson PJ, Hedrich CM. (2017) Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment. Curr Osteoporos Rep 15(6):542-554.

Mentrup B, Girschick H, Jakob F, Hofmann C. (2017) A homozygous intronic branch-point deletion in the ALPL gene causes infantile hypophosphatasia. Bone 94:75-83.

Prelog M. (2017) Tonsillitis – wann und wie behandeln. Der Allgemeinarzt 14:1-7.

Seefried L, Baumann J, Hemsley S, Hofmann C, Kunstmann E, Kiese B, Huang Y, Chivers S, Valentin MA, Borah B, Roubenoff R, Junker U, Jakob F. (2017) Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia. J Clin Invest 127(6):2148-2158.

Segerer F, Seeger K, Maier A, Hagemann C, Schoen C, van der Linden M, Streng A, Rose MA, Liese JG. (2017) Therapy of 645 children with parapneumonic effusion and empyema – a  German nationwide surveillance study. Pediatr Pulmonol 52:540-547.

Silwedel C, Frieauff E, Thomas W, Liese JG, Speer CP. (2017) Secondary haemophagocytic lymphohistiocytosis triggered by postnatally acquired cytomegalovirus infection in a late preterm infant. Infection 45(3):355-359.

Streng A, Grote V, Rack-Hoch A, Liese JG. (2017) Decline of neurological varicella complications in children during the first seven years after the introduction of universal varicella vaccination in Germany, 2005-2011. Pediatr Infect Dis J 36(1):79-86.

Streng A, Liese JG. (2017) Nach der Pandemie ist vor der Pandemie? Krankheitslast durch Influenza A(H1N1)pdm09 bei Kindern in Deutschland nach dem Jahr 2009. Kinder- und Jugendmedizin 17:247-255.

Ugor E, Simon D, Almanzar G, Pap R, Najbauer J, Németh P, Balogh P, Prelog M, Czirják L, Berki T. (2017) Increased proportions of functionally impaired regulatory T cell subsets in systemic sclerosis. Clin Immunol 184:54-62.

2016

Almanzar G, Klein M, Schmalzing M, Hilligardt D, El Hajj N, Kneitz H, Wild V, Rosenwald A, Benoit S, Hamm H, Tony HP, Haaf T, Goebeler M, Prelog M. (2016) Disease Manifestation and Inflammatory Activity as Modulators of Th17/Treg Balance and RORC/FoxP3 Methylation in Systemic Sclerosis. Int Arch Allergy Immunol 171:141-154.

Almanzar G, Mayerl C, Seitz JC, Höfner K, Brunner A, Wild V, Jahn D, Geier A, Fassnacht M, Prelog M. (2016) Expression of 11beta-hydroxysteroid-dehydrogenase type 2 in human thymus. Steroids 110:35-40.

Almanzar G, Schmalzing M, Trippen R, Höfner K, Weißbrich B, Geissinger E, Meyer T, Liese J, Tony HP, Prelog M. (2016) Significant IFNγ responses of CD8+ T cells in CMV-seropositive individuals with autoimmune arthritis J Clin Virol 77:77-84.

Daschkey S, Bienemann K, Schuster V, Kreth HW, Linka RM, Hönscheid A, Fritz G, Johannes C, Fleckenstein B, Kempkes B, Gombert M, Ginzel S, Borkhardt A. (2016) Fatal Lymphoproliferative Disease in Two Siblings Lacking Functional FAAP24. J Clin Immunol 2016;36(7):684-92.

Hofmann C, Seefried L, Jakob F. (2016) Asfotase alfa: enzyme replacement therapy for the treatment of bone disease in hypophosphatasia. Drugs of Today 52(5):1-16.

Hofmann SR, Kubasch AS, Range U, Laass MW, Morbach H, Girschick HJ, Hedrich CM. (2016) Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO). Rheumatol Int 36(6):769-779.

Hofmann SR, Schnabel A, Rösen-Wolff A, Morbach H, Girschick HJ, Hedrich CM. (2016) Chronic Nonbacterial Osteomyelitis: Pathophysiological Concepts and Current Treatment Strategies. J Rheumatol 43(11):1956-1964.

Klein M, Schmalzing M, Almanzar G, Benoit S, Hamm H, Tony HP, Goebeler M, Prelog M. (2016) Contribution of CD8+ T cells to inflammatory cytokine production in systemic sclerosis (SSc). Autoimmunity 49:532-546.

Mentrup B, Girschick H, Jakob F, Hofmann C. (2016) A homozygous intronic branch-point deletion in the ALPL gene causes infantile hypophosphatasia. Bone 94:75-83.

Noster R, de Koning HD, Maier E, Prelog M, Lainka E, Zielinski CE. (2016) Dysregulation of  proinflammatory versus anti-inflammatory human TH17 cell functionalities in the autoinflammatory Schnitzler syndrome. J Allergy Clin Immunol 138:1161-1169.

Prelog M, Hilligardt D, Schmidt CA, Przybylski GK, Leierer J, Almanzar G, El Hajj N, Lesch KP, Arolt V, Zwanzger P, Haaf T, Domschke K. (2016) Hypermethylation of FOXP3 Promoter and Premature Aging of the Immune System in Female Patients with Panic Disorder? PLoS One 11:e0157930.

Prelog M, Gorth P, Zwazl I, Kleines M, Streng A, Zlamy M, Heinz-Erian P, Wiedermann U. (2016) Universal Mass Vaccination Against Rotavirus: Indirect Effects on Rotavirus Infections in Neonates and Unvaccinated Young Infants Not Eligible for Vaccination. J Infect Dis 214:546-555.

Streng A, Wiegering V, Liese JG. (2016) Varicella in paediatric oncology patients in the post-vaccine era – analysis of routine hospital data from Bavaria (Germany), 2005-2011. Pediatr Hematol Oncol. 33(7-8):468-479.

Whyte MP, Rockman-Greenberg C, Ozono K, Riese R, Moseley S, Melian A, Thompson DD, Bishop N, Hofmann C. (2016) Asfotase alfa treatment improves survival for perinatal and infantile hypophosphatasia. J Clin Endocrinol Metab 101(1):334–342.

Zlamy M, Almanzar G, Parson W, Schmidt C, Leierer J, Weinberger B, Jeller V, Unsinn K, Eyrich M, Würzner R, Prelog M. (2016) Efforts of the human immune system to maintain the peripheral CD8+ T cell compartment after childhood thymectomy. Immun Ageing 13:3.

2015

Almanzar G, Schönlaub J, Hammerer-Lercher A, Koppelstaetter C, Bernhard D, Prelog M. (2015) Influence of the delivery modus on subpopulations and replication of lymphocytes in mothers and newborns. Early Hum Dev 91(12):663-670.

Eberhardt CS, Haas JP, Girschick H, Schwarz T, Morbach H, Rösen-Wolff A, Foell D, Dannecker G, Schepp C, Ganser G, Honke N, Eggermann T, Müller-Berghaus J, Wagner N, Ohl K, Tenbrock K. (2015) No association of IL-12p49 pro1.1 polymorphism with juvenile idiopathic arthritis. Pediatr Rheumatol Online J 13(1):61.

Girschick H, Wolf C, Morbach H, Hertzberg C, Lee-Kirsch MA. (2015) Severe immune dysregulation with neurological impairment and minor bone changes in a child with spondyloenchondro-dysplasia due to wo novel mutations in the ACP5 gene. Pediatr Rheumatol Online 13(1):37.

Graser S, Mentrup B, Schneider D, Klein-Hitpass L, Jakob F, Hofmann C. (2015) Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line. Bone 79:150-61.

Herbst M, Gazendam R, Reimnitz D, Sawalle-Belohradsky J, Groll A, Schlegel PG Belohradsky B, Renner E, Klepper J, Grimbacher B, Kuijpers T, Liese J. (2015) Chronic Candida albicans meningitis in a 4-year-old girl with a homozygous mutation in the CARD9 gene (Q295X). Pediatr Infect Dis J 34(9):999-1002.

Hofmann C, Jakob F, Seefried L, Mentrup B, Graser S, Plotkin H, Girschick HJ, Liese J. (2015) Recombinant enzyme replacement therapy in hypophosphatasia. Subcell Biochem 76:323-341.

Hofmann SR, Kubasch AS, Ioannidis C, Rösen-Wolff A, Girschick HJ, Morbach H, Hedrich CM. (2015) Altered expression of IL-10 family cytokines in monocytes from CRMO patients results in enhanced IL-1b expression and release. Clin Immunol 161(2):300-307.

Holl K, Rosenlund M, Giaquinto C, Sifverdal SA, Carmona A, Larcombe J, Garcia-Sicilia J, Fuat A, Muñoz ME, Arroba ML, Sloesen B, Vollmar J, Pirçon JY, Liese JG. (2015) The impact of childhood acute otitis media on parental quality of life in a prospective observational cohort study. Clin Drug Investig 35(10):613-624.

León-Calvijo MA, Leal-Castro AL, Almanzar-Reina GA, Rosas-Pérez JE, García-Castañeda JE, Rivera-Monroy ZJ. (2015) Antibacterial activity of synthetic peptides derived from lactoferricin against Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212. Biomed Res Int 453826.

Liese J, Prelog M. (2015) Impfen und Allergien. Impfkompendium. Hrsg. Spiess, Heininger, Jilg, Georg Thieme Verlag KG 45:306-314.

Liese J, Streng A: Varizellen. In: Spiess, Heininger Jilg (Hrsg) (2015) Impfkompendium, 8. Auflage. Georg-Thieme-Verlag Stuttgart, New York, 298-303.

Ombrello MJ, Remmers EF, Tachmazidou I, et al, Schwarz T. (2015) International Childhood Arthritis Genetics (INCHARGE) Consortium; British Society of Pediatric and Adolescent Rheumatology BSPAR Study Group: HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis. Proc Natl Acad Sci U S A 112(52):15970-15975.

Prelog M. (2015) Immunologie der Entzündung. Kinder- und Jugendmedizin, Schattauer GmbH, Verlag für Medizin und Naturwissenschaften 5:303-312.

Rieber N, Singh A, Öz H, Carevic M, Bouzani M, Amich J, Ost M, Ye Z, Ballbach M, Schäfer I, Mezger M, Klimosch SN, Weber AN, Handgretinger R, Krappmann S, Liese J, Engeholm M, Schüle R, Salih HR,Marodi L, Speckmann C, Grimbacher B, Ruland J, Brown GD, Beilhack A, Loeffler J, Hartl D. (2015) Pathogenic fungi regulate immunity by inducing neutrophilic myeloid-derived suppressor cells. Cell Host Microbe 17(4):507-514.

Streng A, Prifert C, Weissbrich B, Liese JG; Bavarian PICU Study Group on Influenza and Other Viral ARI. (2015) Continued high incidence of children with severe influenza A(H1N1)pdm09 admitted to paediatric intensive care units in Germany during the first three post-pandemic influenza seasons, 2010/11-2012/13. BMC Infect Dis 15:573.

Whyte MP, Rockman-Greenberg C, Ozono K, Riese R, Moseley S, Melian A, Thompson DD, Bishop N, Hofmann C. (2015) Asfotase Alfa Treatment Improves Survival for Perinatal and Infantile Hypophosphatasia. J Clin Endocrinol Metab Epub.

2014

Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B. (2014) Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect. Nature Commun 5:4746.

Gazendam RP, van Hamme JL, Tool AT, van Houdt M, Verkuijlen PJ, Herbst M, Liese JG, van de Verdoonk FL, Roos D, van den Berg TK, Kuijpers TW. (2014) Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects. Blood 124:590-59.

Hofmann C, Wurm M, Schwarz T, Neubauer H, Beer M, Girschick H, Morbach H. (2014) A standardized clinical and radiological follow-up of patients with chronic non bacterial Osteomyelitis treated with pamidronate. Clin Exp Rheumatol Jul-Aug;32(4):604.

Krumbholz A, Neubert A, Joel S, Girschick H, Huppertz HI, Kaiser P, Liese J, Streng A, Niehues T, Peters J, Sauerbrey A, Schroten H, Tenebaum T, Wirth S, Zell R, Sauerbrei A. (2014) Prevalence of hepatitis E virus antibodies in children in Germany. Pediatr Infect Dis J 33:258-26.

Liese JG, Silfverdal SA, Giaquinto C, Carmona A, Larcombe JH, Garcia-Sicilia J, Fuat A, Garces-Sanchez M, Arroba Basanta ML, Hiraldo EM, Cantarutti L, Kroeniger W, Vollmar J, Holl K, Pirçon JY, Roselund MR. (2014) Incidence and clinical presentation of acute otitis media in children aged <6 years in European medical practices. Epidemiol Infect 142:1778-1788 doi:10.1017/S095026881300274.

Liese J, Streng A: Acht Jahre generelle Varizellenimpfung – Akzeptanz, Erfolge, Probleme und Ausblick. In: Bayerisches Staatsministerium für Gesundheit und Pflege (Hrsg. (2014) Impfen – eine gesamtgesellschaftliche Verantwortung. Berichtsband zur 3. Nationalen Impfkonferenz 2013. Asterion Germany GmbH, Viernheim, 26-28; www.nationale-impfkonferenz.de

Rose MA, Damm O, Greiner W, Knuf M, Wutzler P, Liese JG, Krüger H, Wahn U, Schaberg T, Schwehm M, Kochmann TF, Eichner M. (2014) The epidemiological impact of childhood influenza vaccination using live-attenuated influenza vaccine (LAIV) in Germany: predictions of a simulation study. BMC Infect Dis 14:40; doi: 10.1186/1471-2334-14-40.

Sauerbrei A, Langenhan T, Brandstädt A, Schmidt-Ott R, Krumbholz A, von Kries R, Girschick H, Huppertz H-I, Kaiser P, Liese J, Streng A, Niehus T, Peters J, Sauerbrey A, Schroten H, Tenenbaum T, Wirth S, Wutzler P. (2014) Prevalence of antibodies against influenza A and B viruses in children in Germany, 2008 to 2010. Euro Surveill. 19(5):pii=2068.

Streng A, Liese JG. (2014) Decline of varicella vaccination in German surveillance regions after recommendation of separate first-dose vaccination for varicella and measles-mumps-rubella. Vaccine 32:897-900.

Streng A, Liese JG. (2014) Fifteen years of routine childhood varicella vaccination in the United States – strong decrease in the burden of varicella disease and no negative effects on the population level thus far Editorial. Translational Pediatrics 2014;3(4):268-272;doi: 10.3978/j.issn.2224-4336.2014.10.02.

Mornet E, Hofmann C, Bloch-Zupan A, Girschick H, Le Merrer M. (2014) Clinical utility gene card for: Hypophosphatasia – update 2013. Eur J Hum Genet. Apr;22(4).

Morbach H, Girschick HJ: Nichtbakterielle Osteomyelitis. In: Wagner N, Dannecker G (Hrsg). (2014) Pädiatriche Rheumatologie. Springer-Verlag Berlin, Heidelberg, New York, 524-529.

2013

Almanzar G, Ottensmeier B, Liese J, Prelog M (2013)
Assessment of IgG avidity against pertussis toxin and filamentous hemagglutininin via an adapted enzyme-linked immunosorbent assay (ELISA) using ammonium thiocyanate.
J Immunol Methods 387:36-42.

Almanzar G, Zlamy M, Koppelstaetter C, Brunner A, Jeller V, Duftner C, Dejaco C, Brunner J, Prelog M (2013)
Increased replication of CD4+ naive T cells and changes in T cell homeostasis in a case of acute exacerbation of juvenile idiopathic arthritis: a case comparison study.
J Med Case Rep 21;7:135.

Almanzar G, Eberle G, Lassacher A, Specht C, Koppelstaetter C, Heinz-Erian P, Trawöger R, Bernhard D, Prelog M (2013)
Maternal cigarette smoking and its effect on neonatal lymphocyte subpopulations and replication.
BMC Pediatr 18;13:57.

Andres O, Strehl K, Kölsch U, Kunzmann S, Lebrun AH, Stroh T, Schwarz K, Morbach H, von Bernuth H, Liese J (2013)
Even in pneumococcal sepsis CD62L shedding on granulocytes proves to be a reliable functional test for the diagnosis of interleukin-1 receptor-associated kinase-4 deficiency.
Pediatr Infect Dis J 32:1017-9.

Bringmann G, Thomale K, Bischof S, Schneider C, Schultheis M, Schwarz T, Moll H, Schurigt U (2013)
A novel Leishmania major amastigote assay in 96-well format for rapid drug screening and its use for discovery and evaluation of a new class of leishmanicidal quinolinium salts.
Antimicrob Agents Chemother 57:3003-11.

Carbonell-Estrany X, Fullarton JR, Gooch KL, Vo PG, Figueras-Aloy J, Lanari M, Gouyon JB, Liese JG (2013)
Effects of parental and household smoking on the risk of respiratory syncytial virus (RSV) hospitalisation in late-preterm infants and the potential impact of RSV prophylaxis.
J Matern Fetal Neonatal Med 26:926-31.

Hedrich CM, Hofmann SR, Pablik J, Morbach H, Girschick HJ (2013)
Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO).
Pediatr Rheumatol Online J.23;11:47.

Hedrich CM, Hahn G, Girschick HJ, Morbach H (2013)
A clinical and pathomechanistic profile of chronic nonbacterial osteomyelitis/chronic recurrent multifocal osteomyelitis and challenges facing the field.
Expert Rev Clin Immunol 9:845-54.

Hofmann C, Girschick HJ, Mentrup B, Graser S, Seefried L, Liese J, Jakob F (2013)
Clinical aspects of hypophosphatasia:an update.
Clin Rev Bone Miner Metab 11:60-70.

Hofmann C, Liese J, Schwarz T, Kunzmann S, Wirbelauer J, Nowak J, Hamann J, Girschick H, Graser S, Dietz K, Zeck S, Jakob F, Mentrup B (2013)
Compound heterozygosity of two functional null mutations in the ALPL gene associated with deleterious neurological outcome in an infant with hypophosphatasia.
Bone 55:150-7.

Krumbholz A, Neubert A, Girschick H, Huppertz HI, Kaiser P, Liese J, Streng A, Niehus T, Peters J, Sauerbrey A, Schroten H, Tenenbaum T, Wirth S, Sauerbrei A (2013)
Prevalence of antibodies against hepatitis A virus among children and adolescents in Germany.
Med Microbiol Immunol 202:417-24.

Liese J, Abele-Horn M, Beer M, Forster J, Heininger U, Nadal D, Rose M, Scholz H (2013)
Diagnose und Behandlung der Pneumonie im Kindesalter.
Monatsschrift Kinderheilkunde 8:703-712.

Liese JG, Cohen C, Rack A, Pirzer K, Eber S, Blum M, Greenberg M, Streng A (2013)
The effectiveness of varicella vaccination in children in Germany. A case-control study.
Pediatr Infect Dis J 32:998-1004.

Morbach H, Girschick HJ (2013)
B-cell targeted therapy for children and adolescents with rheumatic diseases.
Z Rheumatol 72:347-53.

Morbach H, Hedrich CM, Beer M, Girschick HJ (2013)
Autoinflammatory bone disorders.
Clin Immunol 147:185-96.

Prelog M, Almanzar G, Rieber N, Ottensmeier B, Zlamy M, Liese J (2013)
Differences in IgG antibody avidity after an acellular pertussis (aP) booster in adolescents after a whole cell (wcP) or a aP primary vaccination.
Vaccine 31:387-93.

Prelog M, Egli A, Zlamy M, Hirsch HH (2013)
JC and BK polyomavirus-specific Immunoglobulin G responses in patients thymectomized in early childhood.
J Clin Virol 58:553-558.

Prelog M (2013)
Differential approaches for vaccination from childhood to old age.
Gerontology 59:230-9.

Prelog M, Schönlaub J, Würzner R, Koppelstaetter C, Almanzar G, Brunner A, Gasser M, Prommegger R, Häusler G, Kapelari K, Högler W (2013)
Lower CD28+ T cell proportions were associated with CMV-seropositivity in patients with Hashimoto's thyroiditis.
BMC Endocr Disord 5;13:34.

Prelog M, Schönlaub J, Jeller V, Almanzar G, Höfner K, Gruber S, Eiwegger T, Würzner R (2013)
Reduced varicella-zoster-virus (VZV)-specific lymphocytes and IgG antibody avidity in solid organ transplant recipients.
Vaccine 31:2420-6.


Prifert C, Streng A, Krempl CD, Liese J, Weissbrich B (2013)
Novel Respiratory Syncytial Virus A genotype, Germany, 2011-2012.
Emerg Infect Dis 19:1029-30.

Schwarz T, Remer KA, Nahrendorf W, Masic A, Siewe L, Müller W, Roers A, Moll H (2013)
T cell-derived IL-10 determines leishmaniasis disease outcome and is suppresses by a dendritic cell based vaccine.
PLoS Pathog 9:e1003476.

Segerer F, Morbach H, Hassold N, Kleinert S, Tony HP, Roesler J, Liese J (2013)
A 58-year-old man with respiratory insufficiency after a 50-year history of hypersensitivity pneumonitis and pulmonary Aspergillus infections.
J Allergy Clin Immunol Pract 1:677-80.

Simon A, Muller A, Kaiser P, Topfner N, Berner R, Laws HJ, Knorr M, Hufnagel M, Beyersdorff A, Heister P, Becker C, Liese J, Tenenbaum T (2013)
The Paed IC project-Antibiotic Stewardship and Hospital Hygiene to Prevent Infection with Resistant Pathogens.
Klin Padiatr 225:93-95.

Straßburg HM (2013)
Vaccination ethics and health care.
Klin Padiatr 225:1-2.

Streng A, Grote V, Carr D, Hagemann C, Liese JG (2013)
Varicella routine vaccination and the effects on varicella epidemiology – results from the Bavarian Varicella Surveillance Project (BaVariPro), 2006-2011.
BMC Infect Dis 13:303.

Zlamy M, Kofler S, Orth D, Würzner R, Heinz-Erian P, Streng A, Prelog M (2013)
The impact of Rotavirus mass vaccination on hospitalization rates, nosocomial Rotavirus gastroenteritis and secondary blood stream infections.
BMC Infect Dis 13:112

2012

Brunner J, Prelog M, Riedl M, Giner T, Hofer J, Würzner R, Zimmerhackl LB (2012)
Analysis of the classical, alternative, and mannose binding lectin pathway of the complement system in the pathogenesis of oligoarticular juvenile idiopathic arthritis.

Rheumatol Int 32:1815-8.

Eltermann T, Wössner R, Liese J, Wieg C, Wirbelauer J, Thomas W (2012)
Fatal pertussis in a preterm with hyperleukocytosis and necrotizing enterocolitis: considerations on pathogenesis and prevention.
Klin Padiatr. 224:461-2.

Graser S, Hofmann C, Jakob F, Mentrup B (2012)
Generation and characterization of a neuroblastoma cell line stably expressing the tissue-nonspecific alkaline phosphatase enzyme TNSALP.
Bone. 50 1:S175-S176.

Hofmann SR, Morbach H, Schwarz T, Rösen-Wolff A, Girschick HJ, Hedrich CM (2012)
Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression.
Clin Immunol 145:69-76.

Hofmann C, Schwarz T, Kunzmann S, Wirbelauer J, Beer M, Girschick H, Willascheck C, Buchhorn R, Kreher N, Plotkin H, Landy H, Liese J (2012)
Enzyme replacement therapy in different clinical phenotypes of hypophosphatasia – presentation of two cases.
Bull Group Int Rech Sci Stomatol Odontol 2012;51(1):e36.

Krudewig J, Baumann U, Bernuth von H, Borte M, Burkhard-Meier U, Dueckers G, Foerster-Waldl E, Franke K, Habermehl P, Hönig M, Kern W, Kösters K, Kugel K, Lehrnbecher T, Liese J, Marks R, Müller GA, Müller R, Nadal D, Peter HH, Pfeiffer-Kascha D, Schneider M, Sitter H, Späth P, Wahn V, Welte T, Niehues T (2012)
Interdisciplinary AWMF Guideline for the treatment of primary antibody deficiencies. 
Klin Padiatr 224:404-15.

Lam TT, Claus H, Elias J, Hellenbrand W, Imöhl M, Prelog M, Sing A, van der Linden M, Vogel U (2012)
Infections with Pneumococci, Meningococci, H. influenza and Diphtheria in Germany: the RKI Reference Network for Invasive Bacterial Infections (IBI) at the 5th Würzburg Workshop on Epidemiology, Prevention and Therapy for Invasive Meningococcal Diseases 2010 (Meeting Report).
Gesundheitswesen 74:747-53.

Mayerl C, Prelog M (2012)
Immunosenescence and juvenile idiopathic arthritis.
Autoimm Rev 1:297-300.

Mentrup B, Sabrautzki S, Hofmann C, de Angelis MH, Jakob F (2012)
In vitro characterization of TNSALP mutations from two novel mouse models for hypophosphatasia.
Bone 50 1:S168-S168.

Morbach H, Schneider P, Schwarz T, Hofmann C, Raab P, Neubauer H, Düren C, Beer M, Girschick HJ (2012)
Comparison of magnetic resonance imaging and 99mTechnetium-labelled methylene diphosphonate bone scintigraphy in the initial assessment of chronic non-bacterial osteomyelitis of childhood and adolescents.
Clin Exp Rheumatol 30:578-82.

Neubauer H, Evangelista L, Morbach H, Girschick H, Prelog M, Köstler H, Hahn D, Beer M (2012)
Diffusion-weighted MRI of bone marrow oedema, soft tissue oedema and synovitis in paediatric patients: feasibility and initial experience.
Pediatr Rheumatol Online 10:20.

Neubauer H, Platzer I, Mueller VR, Meyer T, Liese J, Koestler H, Hahn D, Beer M (2012)
Diffusion-weighted MRI of abscess formations in children and young adults.
World J Pediatr 8:229-34.

Roesler J, Segerer F, Morbach H, Kleinert S, Thieme S, Rösen-Wolff A, Liese JG (2012)
P67-phox (NCF2) lacking exons 11 and 12 is functionally active and leads to an extremely late diagnosis of chronic granulomatous disease (CGD).
PLoS One 7:e34296.

Simon A, Mühlenborn E, Prelog M, Schenk W, Holzapfel J, Ebinger F, Klabunde-Cherwon A, Faber J, Groll A, Masjosthusmann K, Dohna-Schwake C, Beutel K, Lehrnbecher T, Ammann R, Müller A (2012)
Use of linezolid in neonatal and pediatric inpatient facilities-results of a retrospective multicenter survey.
Eur J Clin Micr Infect Dis 31:1435-42.

Wieching A, Benser J, Kohlhauser-Vollmuth C, Weissbrich B, Streng A, Liese J (2012)
Clinical characteristics of pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Northern Bavaria, Germany.
BMC Research Notes 5:304.

Zlamy M, Hofer J, Elias J, Vogel U, Frosch M, Jungraithmayr T, Zimmerhackl LB, Prelog M (2012)
Immunogenicity of meningococcus C vaccination in a patient with atipica hemolytic uremic syndrome (aHUS) on eculizumab therapy.
Pediatr Transpl 16:E246-50
.

2011

Beck C, Girschick HJ, Morbach H, Schwarz T, Frenkel J, van Gijn ME(2011)
Mutations of the IL-1 receptor antagonist gene are not associated with chronic nonbacterial osteomyelitis of childhood and adolescence.
Clin Exp Rheumatol 29:1040-3.

Beck C, Morbach H, Wirth C, Beer M, Girschick HJ (2011)
Whole-body MRI in the childhood form of hypophosphatasia.
Rheumatol Int. 31:1315-20.

Benser J, Streng A, Liese J (2011)
Bedeutung der Influenza im Kindesalter.
Kinderärztl Praxis 82:28-30.

Farmand S, Baumann U, von Bernuth H, Borte M, Foerster-Waldl E, Franke K, Habermehl P, Kapaun P, Klock G, Liese J, Marks R, Müller R, Nebe T, Niehues T, Schuster V, Warnatz K, Witte T, Ehl S, Schulze I (2011)
Interdisciplinary AWMF guideline for the diagnostics of primary immunodeficiency.
Klin Padiatr 223:378-85.

Guiso N, Liese J, Plotkin S (2011)
The Global Pertussis initiative: meeting report from the fourth regional roundtable meeting.
Hum Vaccin 7:481-8.

Hofmann SR, Schwarz T, Möller JC, Morbach H, Schnabel A, Rösen-Wolff A, Girschick HJ, Hedrich CM (2011)
Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced IL10 promoter phosphorylation, and reduced myeloid IL-10 expression.
Clin Immunol 141:317-27.

Kunze U, the ISW TBE (Prelog M et al.) (2011)
Tick-borne encephalitis: the impact of epidemiology, changing lifestyle, and environmental factors. Conference report of the 12th Annual Meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE).
Vaccine 29:1355-6.

Liese JG (2011)
Challenges in the differential diagnosis of aseptic meningo-encephalitis in children.
Klin Padiatr 223:207-8.

Liese J. (2011)
Pertussis.Eine Kinderkrankheit wird erwachsen und erfordert neue Präventionsstrategien.
Kinder Jugendmed 3:144-6.

Mentrup B, Marschall C, Barvencik F, Amling M, Jakob F, Beck C (2011)
Functional characterization of a novel mutation localized in the start codon of the tissue-nonspecific alkaline phosphatase gene.
Bone 48:1401-8.

Morbach H, Wiegering V, Richl P, Schwarz T, Suffa N, Eichhorn EM, Eyrich M, Girschick HJ (2011)
Activated memory B cells may function as antigen-presenting cells in the joints of children with juvenile idiopathic arthritis.
Arthritis Rheum 63:3458-66.

Neubauer H, Morbach H, Schwarz T, Wirth C, Girschick HJ, Beer M (2011)
Popliteal cysts in paediatric patients: clinical characteristics and imaging features on ultrasound and MRI.
Arthritis 2011:751593.

Plotkin SA, Liese J, Madhi SA, Ortiz E (2011)
A DTaP-IPV//PRP~T vaccine (Pentaxim): a review of 16 years' clinical experience.
Expert Rev Vaccines 10:981-1005.

Prelog M (2011)
Immune-aging and autoimmune disease in children.
Curr Immunol Rev 7:116-23.

Prelog M, Schönlaub J, Zimmerhackl LB (2011)
Aciclovir and Varicella-zoster-immunoglobulin in solid organ transplant recipients.
Pediatr Nephrol 26:663-73.

Rieber N, Graf A, Hartl D, Urschel S, Belohradsky BH, Liese J (2011)
Acellular pertussis booster in adolescents induces Th1 and memory CD8+ T cell immune response.
PLoS One. 6:e17271.

Simões EA, Carbonell-Estrany X, Fullarton JR, Rossi GA, Barberi I, Lanari M; European RSV Risk Factor Study Group (2011)
European risk factors' model to predict hospitalization of premature infants born 33-35 weeks' gestational age with respiratory syncytial virus: validation with Italian data.
J Matern Fetal Neonatal Med 24:152-7.

Streng A, Grote V, Liese JG (2011)
Severe influenza cases in paediatric intensive care units in Germany during the pre-pandemic seasons 2005 to 2008.
BMC Infect Dis 11:233.

Von Kries R, Weiss S, Falkenhorst G, Wirth S, Kaiser P, Huppertz HI, Tenenbaum T, Schroten H, Streng A, Liese J, Shai S, Niehues T, Girschick H, Kuscher E, Sauerbrey A, Peters J, Wirsing von König CH, Rückinger S, Hampl W, Michel D, Mertens T (2011)
Post-pandemic seroprevalence of pandemic influenza A (H1N1) 2009 infection (swine flu) among children <18 years in Germany.
PLoS One 6:e23955.

Weiß S, Streng A, Kries RV, Liese J, Wirth S, Jenke AC (2011)
Incidence of intussusception in early infancy: a capture-recapture estimate for Germany.
Klin Padiatr 223:419-423.

Wiegering V, Kaiser J, Tappe D, Weissbrich B, Morbach H, Girschick HJ (2011)
Gastroenteritis in childhood: a retrospective study of 650 hospitalized pediatric patients.
Int J Infect Dis 15:e401-7.

Wiegering V, Schick J, Beer M, Weissbrich B, Gattenlöhner S, Girschick HJ, Liese J, Schlegel PG, Eyrich M (2011)
Varicella-zoster virus infections in immunocompromised patients - a single centre 6-years analysis.
BMC Pediatr 2011;11:31.

Zlamy M, Elias J, Vogel U, Frosch M, Jeller V, Cortina G, Jungraithmayr T, Prelog M (2011)
Immunogenicity of conjugate Meningococcus C vaccine in pediatric solid organ transplant recipients.
Vaccine 29:6163-.

2010

Albers HM, Brinkman DM, Kamphuis SS, van Suijlekom-Smit LW, van Rossum MA, Hoppenreijs EP, Girschick HJ, Wouters C, Saurenmann RK, Houwing-Duistermaat JJ, Huizinga TW, Schilham MW, ten Cate R (2010)
Clinical course and prognostic value of disease activity in the first two years in different subtypes of juvenile idiopathic arthritis.
Arthritis Care Res (Hoboken) 62:204-212.

Appay V, Sauce D, Prelog M (2010)
The role of the thymus in immunosenescence: lessons from the study of thymectomized individuals.
Aging (Albany NY) 2:78-81.

Arguedas A, Kvaerner K, Liese J, Schilder AG, Pelton SI (2010)
Otitis media across nine countries: disease burden and management.
Int J Pediatr Otorhinolaryngol 74:1419-1424.

Beck C, Morbach H, Beer M, Stenzel M, Tappe D, Gattenlohner S, Hofmann U, Raab P, Girschick HJ (2010)
Chronic nonbacterial osteomyelitis in childhood: prospective follow-up during the first year of anti-inflammatory treatment.
Arthritis Res Ther 12:R74.

Beck C, Morbach H, Wirth C, Beer M, Girschick HJ (2010)
Whole-body MRI in the childhood form of hypophosphatasia.
Rheumatol Int.

Brunner J, Moschovakis G, Prelog M, Walder G, Wuerzner R, Zimmerhackl LB (2010)
Lyme neuroborreliosis: aetiology and diagnosis of facial palsy in children from Tyrol.
Klin Padiatr 222:302-307.

Carbonell-Estrany X, Simões EA, Dagan R, Hall CB, Harris B, Hultquist M, Connor EM, Losonsky GA; Motavizumab Study Group (2010)
Motavizumab for prophylaxis of respiratory syncytial virus in high-risk children: a noninferiority trial.
Pediatrics 125:e35-51.

Humrich JY, Morbach H, Undeutsch R, Enghard P, Rosenberger S, Weigert O, Kloke L, Heimann J, Gaber T, Brandenburg S, Scheffold A, Huehn J, Radbruch A, Burmester GR, Riemekasten G (2010)
Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.
Proc Natl Acad Sci U S A 107:204-209.

Kohl LJ, Streng A, Grote V, Koletzko S, Liese JG (2010)
Intussusception-associated hospitalisations in southern Germany.
Eur J Pediatr 169:1487-1493.

Kümmerle-Deschner JB, Tyrrell PN, Reess F, Kötter I, Lohse P, Girschick H, Huemer C, Horneff G, Haas JP, Koitschev A, Deuter C, Benseler SM (2010)
Risk factors for severe Muckle-Wells syndrome.
Arthritis Rheum 62:3783-91.

Liese JG, Rieber N, Malzer T, Ocak M, Johnson DR, Decker MD (2010)
Reactogenicity of tetanus, diphtheria, 5-component acellular pertussis vaccine administered as a sixth consecutive acellular pertussis vaccine dose to adolescents.
Pediatr Infect Dis J 29:1067-1071
.

Morbach H, Dannecker H, Kerkau T, Girschick HJ (2010)
Prevalence of antibodies against mutated citrullinated vimentin and cyclic citrullinated peptide in children with juvenile idiopathic arthritis.
Clin Exp Rheumatol 28:800.

Morbach H, Dick A, Beck C, Stenzel M, Muller-Hermelink HK, Raab P, Girschick HJ (2010)
Association of chronic non-bacterial osteomyelitis with Crohn's disease but not with CARD15 gene variants.
Rheumatol Int 30:617-621.

Morbach H, Eichhorn EM, Liese JG, Girschick HJ (2010)
Reference values for B cell subpopulations from infancy to adulthood.
Clin Exp Immunol 162:271-279.

Mornet E, Beck C, Bloch-Zupan A, Girschick H, Le Merrer M (2010)
Clinical utility gene card for: hypophosphatasia.
Eur J Hum Genet 19.

Prelog M, Zimmerhackl LB (2010)
Varicella vaccination in pediatric kidney and liver transplantation.
Pediatr Transplant 14:41-47.

Rack AL, Grote V, Streng A, Belohradsky BH, Heinen F, von Kries R, Liese JG (2010)
Neurologic varicella complications before routine immunization in Germany.
Pediatr Neurol 42:40-48.

Stoevesandt J, Morbach H, Martin TM, Zierhut M, Girschick H, Hamm H (2010)
Sporadic Blau syndrome with onset of widespread granulomatous dermatitis in the newborn period.
Pediatr Dermatol 27:69-73.

Streng A, Seeger K, Grote V, Liese JG (2010)
Varicella vaccination coverage in Bavaria (Germany) after general vaccine recommendation in 2004.
Vaccine 28:5738-5745.

Vergison A, Dagan R, Arguedas A, Bonhoeffer J, Cohen R, Dhooge I, Hoberman A, Liese J, Marchisio P, Palmu AA, Ray GT, Sanders EA, Simoes EA, Uhari M, van Eldere J, Pelton SI (2010)
Otitis media and its consequences: beyond the earache.
Lancet Infect Dis 10: 195-203.

Von Chamier G, Holl-Wieden A, Stenzel M, Raab P, Darge K, Girschick HJ, Beer M (2010)
Pitfalls in diagnostics of hip pain: osteoid osteoma and osteoblastoma. Rheumatol Int 30:395-400.

Wiegering V, Balling G, Wirbelauer J, Sturm A, Girschick HJ (2010)
Post varicella disseminated intravascular coagulation and transient protein S deficiency in an otherwise healthy 6-year-old boy: a case report.
Infection 38:505-508.

Wiegering V, Girschick HJ, Morbach H (2010): B-cell pathophysiology in juvenile idiopathic arthritis. Arthritis Article ID 759868.

Wiegering V, Morbach H, Dick A, Girschick HJ (2010)
Crohn's disease during etanercept therapy in juvenile idiopathic arthritis: a case report and review of the literature.
Rheumatol Int 30:801-804.

Zlamy M, Wurzner R, Holzmann H, Brandstatter A, Jeller V, Zimmerhackl LB, Prelog M (2010)
Antibody dynamics after tick-borne encephalitis and measles-mumps-rubella vaccination in children post early thymectomy.
Vaccine 28:8053-8060. 

Buchbeiträge

2022

Hedrich CM, Morbach H, Girschick HJ (2022) 
Nichbakterielle Osteomyelitis bei Kindern und Jugendlichen.
Pädiatrische Rheumatologie 2022, 3. Auflage, Hrsg. Wagner N, Dannecker G, Kallinic T, Springer
.

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